Genetic variation in aldo-keto reductase 1D1 (AKR1D1) affects the expression and activity of multiple cytochrome P450s

Drug Metabolism and Disposition

Volumn 41, Issue 8, 2013, Pages 1538-1547

  Chaudhry, Amarjit S ^a   Thirumaran, Ranjit K ^a   Yasuda, Kazuto ^a   Yang, Xia ^b   Fan, Yiping ^a   Strom, Stephen C ^c   Schuetz, Erin G ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALDO KETO REDUCTASE 1D1; BILE ACID; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; FARNESOID X RECEPTOR; LUCIFERASE; MESSENGER RNA; OXIDOREDUCTASE; PREGNANE X RECEPTOR; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; AMINO ACID SEQUENCE; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME ANALYSIS; GENE EXPRESSION; GENE REGULATORY NETWORK; GENE SILENCING; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER MICROSOME; LIVER PARENCHYMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; RNA STABILITY; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION REGULATION;

ALTERNATIVE SPLICING; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENETIC VARIATION; HEP G2 CELLS; HEPATOCYTES; HUMANS; LIVER; OXIDOREDUCTASES; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA, MESSENGER;

EID: 84880671190     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.113.051672     Document Type: Article

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