메뉴 건너뛰기




Volumn 210, Issue 7, 2013, Pages 1447-1462

T cell-derived inducible nitric oxide synthase switches offth17 cell differentiation

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; N ACETYL S NITROSOPENICILLAMINE; N6 (1 IMINOETHYL)LYSINE; NEURONAL NITRIC OXIDE SYNTHASE; RETINOID RELATED ORPHAN RECEPTOR GAMMA;

EID: 84880662741     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20122494     Document Type: Article
Times cited : (101)

References (51)
  • 1
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E., Y. Carrier, W. Gao, T. Korn, T.B. Strom, M. Oukka, H.L. Weiner, and V.K. Kuchroo. 2006. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 441:235-238. http://dx.doi.org/10.1038/nature04753
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 2
    • 35348960243 scopus 로고    scopus 로고
    • Th17: the third member of the effector T cell trilogy
    • Bettelli, E., T. Korn, and V.K. Kuchroo. 2007. Th17: the third member of the effector T cell trilogy. Curr. Opin. Immunol. 19:652-657. http://dx.doi.org/10.1016/j.coi.2007.07.020
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 652-657
    • Bettelli, E.1    Korn, T.2    Kuchroo, V.K.3
  • 3
    • 0032482189 scopus 로고    scopus 로고
    • The multiplex function of nitric oxide in (auto)immunity
    • Bogdan, C. 1998. The multiplex function of nitric oxide in (auto)immunity. J. Exp. Med. 187:1361-1365. http://dx.doi.org/10.1084/jem.187.9.1361
    • (1998) J. Exp. Med. , vol.187 , pp. 1361-1365
    • Bogdan, C.1
  • 4
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • Bogdan, C. 2001. Nitric oxide and the immune response. Nat. Immunol. 2:907-916. http://dx.doi.org/10.1038/ni1001-907
    • (2001) Nat. Immunol , vol.2 , pp. 907-916
    • Bogdan, C.1
  • 5
    • 0033968432 scopus 로고    scopus 로고
    • The role of nitric oxide in innate immunity
    • Bogdan, C., M. Röllinghoff, and A. Diefenbach. 2000. The role of nitric oxide in innate immunity. Immunol. Rev. 173:17-26. http://dx.doi.org/10.1034/j.1600-065X.2000.917307.x
    • (2000) Immunol. Rev. , vol.173 , pp. 17-26
    • Bogdan, C.1    Röllinghoff, M.2    Diefenbach, A.3
  • 8
    • 79952229169 scopus 로고    scopus 로고
    • Nitric oxide controls an inflammatory-like Ly6C(hi)PDCA1+ DC subset that regulates Th1 immune responses
    • Giordano, D., C. Li, M.S. Suthar, K.E. Draves, D.Y. Ma, M. Gale Jr., and E.A. Clark. 2011. Nitric oxide controls an inflammatory-like Ly6C(hi)PDCA1+ DC subset that regulates Th1 immune responses. J. Leukoc. Biol. 89:443-455. http://dx.doi.org/10.1189/jlb.0610329
    • (2011) J. Leukoc. Biol. , vol.89 , pp. 443-455
    • Giordano, D.1    Li, C.2    Suthar, M.S.3    Draves, K.E.4    Ma, D.Y.5    Gale Jr., M.6    Clark, E.A.7
  • 9
    • 0028902552 scopus 로고
    • Nitric oxide synthases: properties and catalytic mechanism
    • Griffith, O.W., and D.J. Stuehr. 1995. Nitric oxide synthases: properties and catalytic mechanism. Annu. Rev. Physiol. 57:707-736. http://dx.doi.org/10.1146/annurev.ph.57.030195.003423
    • (1995) Annu. Rev. Physiol. , vol.57 , pp. 707-736
    • Griffith, O.W.1    Stuehr, D.J.2
  • 11
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington, L.E., R.D. Hatton, P.R. Mangan, H. Turner, T.L. Murphy, K.M. Murphy, and C.T. Weaver. 2005. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 6:1123-1132. http://dx.doi.org/10.1038/ni1254
    • (2005) Nat. Immunol. , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 12
    • 0031795118 scopus 로고    scopus 로고
    • Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages
    • <4062::AID-IMMU4062>3.0.CO;2-K
    • Huang, F.P., W. Niedbala, X.Q. Wei, D. Xu, G.J. Feng, J.H. Robinson, C. Lam, and F.Y. Liew. 1998. Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages. Eur. J. Immunol. 28:4062-4070. http://dx.doi.org/10.1002/(SICI)1521-4141(199812)28:12<4062::AID-IMMU4062>3.0.CO;2-K
    • (1998) Eur. J. Immunol. , vol.28 , pp. 4062-4070
    • Huang, F.P.1    Niedbala, W.2    Wei, X.Q.3    Xu, D.4    Feng, G.J.5    Robinson, J.H.6    Lam, C.7    Liew, F.Y.8
  • 14
    • 13244284790 scopus 로고    scopus 로고
    • Pathophysiological functions of nitric oxide-mediated protein modifications
    • Ischiropoulos, H., and A. Gow. 2005. Pathophysiological functions of nitric oxide-mediated protein modifications. Toxicology. 208:299-303. http://dx.doi.org/10.1016/j.tox.2004.11.018
    • (2005) Toxicology , vol.208 , pp. 299-303
    • Ischiropoulos, H.1    Gow, A.2
  • 15
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
    • Ivanov, I.I., B.S. McKenzie, L. Zhou, C.E. Tadokoro, A. Lepelley, J.J. Lafaille, D.J. Cua, and D.R. Littman. 2006. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell. 126:1121-1133. http://dx.doi.org/10.1016/j.cell.2006.07.035
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3    Tadokoro, C.E.4    Lepelley, A.5    Lafaille, J.J.6    Cua, D.J.7    Littman, D.R.8
  • 16
    • 4444221709 scopus 로고    scopus 로고
    • T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation
    • Jackson, S.H., S. Devadas, J. Kwon, L.A. Pinto, and M.S. Williams. 2004. T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation. Nat. Immunol. 5:818-827. http://dx.doi.org/10.1038/ni1096
    • (2004) Nat. Immunol. , vol.5 , pp. 818-827
    • Jackson, S.H.1    Devadas, S.2    Kwon, J.3    Pinto, L.A.4    Williams, M.S.5
  • 17
    • 33644850478 scopus 로고    scopus 로고
    • Nitration of tyrosine 92 mediates the activation of rat microsomal glutathione s-transferase by peroxynitrite
    • Ji, Y., I. Neverova, J.E. Van Eyk, and B.M. Bennett. 2006. Nitration of tyrosine 92 mediates the activation of rat microsomal glutathione s-transferase by peroxynitrite. J. Biol. Chem. 281:1986-1991. http://dx.doi.org/10.1074/jbc. M509480200
    • (2006) J. Biol. Chem. , vol.281 , pp. 1986-1991
    • Ji, Y.1    Neverova, I.2    Van Eyk, J.E.3    Bennett, B.M.4
  • 18
    • 12844264783 scopus 로고    scopus 로고
    • S-Nitrosoglutathione reduces inflammation and protects brain against focal cerebral ischemia in a rat model of experimental stroke
    • Khan, M., B. Sekhon, S. Giri, M. Jatana, A.G. Gilg, K. Ayasolla, C. Elango, A.K. Singh, and I. Singh. 2005. S-Nitrosoglutathione reduces inflammation and protects brain against focal cerebral ischemia in a rat model of experimental stroke. J. Cereb. Blood Flow Metab. 25:177-192. http://dx.doi.org/10.1038/sj.jcbfm.9600012
    • (2005) J. Cereb. Blood Flow Metab , vol.25 , pp. 177-192
    • Khan, M.1    Sekhon, B.2    Giri, S.3    Jatana, M.4    Gilg, A.G.5    Ayasolla, K.6    Elango, C.7    Singh, A.K.8    Singh, I.9
  • 19
    • 33746861531 scopus 로고    scopus 로고
    • Cerebrovascular protection by various nitric oxide donors in rats after experimental stroke
    • Khan, M., M. Jatana, C. Elango, A.S. Paintlia, A.K. Singh, and I. Singh. 2006. Cerebrovascular protection by various nitric oxide donors in rats after experimental stroke. Nitric Oxide. 15:114-124. http://dx.doi.org/10.1016/j.niox.2006.01.008
    • (2006) Nitric Oxide , vol.15 , pp. 114-124
    • Khan, M.1    Jatana, M.2    Elango, C.3    Paintlia, A.S.4    Singh, A.K.5    Singh, I.6
  • 20
    • 34547232503 scopus 로고    scopus 로고
    • IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
    • Korn, T., E. Bettelli, W. Gao, A. Awasthi, A. Jäger, T.B. Strom, M. Oukka, and V.K. Kuchroo. 2007. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature. 448:484-487. http://dx.doi.org/10.1038/nature05970
    • (2007) Nature , vol.448 , pp. 484-487
    • Korn, T.1    Bettelli, E.2    Gao, W.3    Awasthi, A.4    Jäger, A.5    Strom, T.B.6    Oukka, M.7    Kuchroo, V.K.8
  • 22
    • 79959566034 scopus 로고    scopus 로고
    • Nitric oxide modulates TGF-beta-directive signals to suppress Foxp3+ regulatory T cell differentiation and potentiate Th1 development
    • Lee, S.W., H. Choi, S.Y. Eun, S. Fukuyama, and M. Croft. 2011. Nitric oxide modulates TGF-beta-directive signals to suppress Foxp3+ regulatory T cell differentiation and potentiate Th1 development. J. Immunol. 186: 6972-6980. http://dx.doi.org/10.4049/jimmunol.1100485
    • (2011) J. Immunol , vol.186 , pp. 6972-6980
    • Lee, S.W.1    Choi, H.2    Eun, S.Y.3    Fukuyama, S.4    Croft, M.5
  • 23
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • Liang, S.C., X.Y. Tan, D.P. Luxenberg, R. Karim, K. Dunussi-Joannopoulos, M. Collins, and L.A. Fouser. 2006. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J. Exp. Med. 203:2271-2279. http://dx.doi.org/10.1084/jem.20061308
    • (2006) J. Exp. Med. , vol.203 , pp. 2271-2279
    • Liang, S.C.1    Tan, X.Y.2    Luxenberg, D.P.3    Karim, R.4    Dunussi-Joannopoulos, K.5    Collins, M.6    Fouser, L.A.7
  • 25
    • 60749107176 scopus 로고    scopus 로고
    • The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo
    • McGeachy, M.J., Y. Chen, C.M. Tato, A. Laurence, B. Joyce-Shaikh, W.M. Blumenschein, T.K. McClanahan, J.J. O'Shea, and D.J. Cua. 2009. The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nat. Immunol. 10:314-324. http://dx.doi.org/10.1038/ni.1698
    • (2009) Nat. Immunol. , vol.10 , pp. 314-324
    • McGeachy, M.J.1    Chen, Y.2    Tato, C.M.3    Laurence, A.4    Joyce-Shaikh, B.5    Blumenschein, W.M.6    McClanahan, T.K.7    O'Shea, J.J.8    Cua, D.J.9
  • 26
    • 0025883342 scopus 로고
    • Nitric oxide: physiology, pathophysiology, and pharmacology
    • Moncada, S., R.M. Palmer, and E.A. Higgs. 1991. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43:109-142.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 27
    • 77954563433 scopus 로고    scopus 로고
    • S-nitrosoglutathione a physiologic nitric oxide carrier attenuates experimental autoimmune encephalomyelitis
    • Nath, N., O. Morinaga, and I. Singh. 2010. S-nitrosoglutathione a physiologic nitric oxide carrier attenuates experimental autoimmune encephalomyelitis. J. Neuroimmune Pharmacol. 5:240-251. http://dx.doi.org/10.1007/s11481-009-9187-x
    • (2010) J. Neuroimmune Pharmacol. , vol.5 , pp. 240-251
    • Nath, N.1    Morinaga, O.2    Singh, I.3
  • 28
    • 33750374586 scopus 로고    scopus 로고
    • Role of nitric oxide in the regulation of T cell functions
    • Niedbala, W., B. Cai, and F.Y. Liew. 2006. Role of nitric oxide in the regulation of T cell functions. Ann. Rheum. Dis. 65:iii37-iii40. http://dx.doi.org/10.1136/ard.2006.058446
    • (2006) Ann. Rheum. Dis. , vol.65
    • Niedbala, W.1    Cai, B.2    Liew, F.Y.3
  • 31
    • 0031056103 scopus 로고    scopus 로고
    • Nitric oxide via an inducible isoform of nitric oxide synthase is a possible factor to eliminate inflammatory cells from the central nervous system of mice with experimental allergic encephalomyelitis
    • Okuda, Y., S. Sakoda, H. Fujimura, and T. Yanagihara. 1997. Nitric oxide via an inducible isoform of nitric oxide synthase is a possible factor to eliminate inflammatory cells from the central nervous system of mice with experimental allergic encephalomyelitis. J. Neuroimmunol. 73:107-116. http://dx.doi.org/10.1016/S0165-5728(96)00194-4
    • (1997) J. Neuroimmunol. , vol.73 , pp. 107-116
    • Okuda, Y.1    Sakoda, S.2    Fujimura, H.3    Yanagihara, T.4
  • 32
    • 79956279442 scopus 로고    scopus 로고
    • Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation
    • Ouyang, X., R. Zhang, J. Yang, Q. Li, L. Qin, C. Zhu, J. Liu, H. Ning, M.S. Shin, M. Gupta, et al. 2011. Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation. Nat Commun. 2:314. http://dx.doi.org/10.1038/ncomms1311
    • (2011) Nat Commun. , vol.2 , pp. 314
    • Ouyang, X.1    Zhang, R.2    Yang, J.3    Li, Q.4    Qin, L.5    Zhu, C.6    Liu, J.7    Ning, H.8    Shin, M.S.9    Gupta, M.10
  • 33
    • 33744984393 scopus 로고    scopus 로고
    • Pharmacological strategies for the regulation of inducible nitric oxide synthase: neurodegenerative versus neuroprotective mechanisms
    • Pannu, R., and I. Singh. 2006. Pharmacological strategies for the regulation of inducible nitric oxide synthase: neurodegenerative versus neuroprotective mechanisms. Neurochem. Int. 49:170-182. http://dx.doi.org/10.1016/j.neuint.2006.04.010
    • (2006) Neurochem. Int. , vol.49 , pp. 170-182
    • Pannu, R.1    Singh, I.2
  • 34
    • 0027517545 scopus 로고
    • Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice
    • Powrie, F., M.W. Leach, S. Mauze, L.B. Caddle, and R.L. Coffman. 1993. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. Int. Immunol. 5:1461-1471. http://dx.doi.org/10.1093/intimm/5.11.1461
    • (1993) Int. Immunol. , vol.5 , pp. 1461-1471
    • Powrie, F.1    Leach, M.W.2    Mauze, S.3    Caddle, L.B.4    Coffman, R.L.5
  • 35
    • 33751559370 scopus 로고    scopus 로고
    • GSNO attenuates EAE disease by S-nitrosylation-mediated modulation of endothelial- monocyte interactions
    • Prasad, R., S. Giri, N. Nath, I. Singh, and A.K. Singh. 2007. GSNO attenuates EAE disease by S-nitrosylation-mediated modulation of endothelial- monocyte interactions. Glia. 55:65-77. http://dx.doi.org/10.1002/glia.20436
    • (2007) Glia , vol.55 , pp. 65-77
    • Prasad, R.1    Giri, S.2    Nath, N.3    Singh, I.4    Singh, A.K.5
  • 36
    • 1642570319 scopus 로고    scopus 로고
    • Nitric oxide, oxidants, and protein tyrosine nitration
    • USA
    • Radi, R. 2004. Nitric oxide, oxidants, and protein tyrosine nitration. Proc. Natl. Acad. Sci. USA. 101:4003-4008. http://dx.doi.org/10.1073/pnas.0307446101
    • (2004) Proc. Natl. Acad. Sci. , vol.101 , pp. 4003-4008
    • Radi, R.1
  • 37
    • 33747593830 scopus 로고    scopus 로고
    • Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
    • Stumhofer, J.S., A. Laurence, E.H. Wilson, E. Huang, C.M. Tato, L.M. Johnson, A.V. Villarino, Q. Huang, A. Yoshimura, D. Sehy, et al. 2006. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat. Immunol. 7:937-945. http://dx.doi.org/10.1038/ni1376
    • (2006) Nat. Immunol. , vol.7 , pp. 937-945
    • Stumhofer, J.S.1    Laurence, A.2    Wilson, E.H.3    Huang, E.4    Tato, C.M.5    Johnson, L.M.6    Villarino, A.V.7    Huang, Q.8    Yoshimura, A.9    Sehy, D.10
  • 38
    • 0029559627 scopus 로고
    • Lack of inducible nitric oxide synthase activity in T cell clones and T lymphocytes from naive and Leishmania major-infected mice
    • Thüring, H., S. Stenger, D. Gmehling, M. Röllinghoff, and C. Bogdan. 1995. Lack of inducible nitric oxide synthase activity in T cell clones and T lymphocytes from naive and Leishmania major-infected mice. Eur. J. Immunol. 25:3229-3234. http://dx.doi.org/10.1002/eji.1830251205
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3229-3234
    • Thüring, H.1    Stenger, S.2    Gmehling, D.3    Röllinghoff, M.4    Bogdan, C.5
  • 40
    • 32244442562 scopus 로고    scopus 로고
    • TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen, M., R.J. Hocking, C.J. Atkins, R.M. Locksley, and B. Stockinger. 2006. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity. 24:179-189. http://dx.doi.org/10.1016/j.immuni.2006.01.001
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 42
    • 33744984785 scopus 로고    scopus 로고
    • Th17: an effector CD4 T cell lineage with regulatory T cell ties
    • Weaver, C.T., L.E. Harrington, P.R. Mangan, M. Gavrieli, and K.M. Murphy. 2006. Th17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity. 24:677-688. http://dx.doi.org/10.1016/j.immuni.2006.06.002
    • (2006) Immunity , vol.24 , pp. 677-688
    • Weaver, C.T.1    Harrington, L.E.2    Mangan, P.R.3    Gavrieli, M.4    Murphy, K.M.5
  • 43
    • 81355148789 scopus 로고    scopus 로고
    • Deciphering the role of Th17 cells in human disease
    • Wilke, C.M., K. Bishop, D. Fox, and W. Zou. 2011. Deciphering the role of Th17 cells in human disease. Trends Immunol. 32:603-611. http://dx.doi.org/10.1016/j.it.2011.08.003
    • (2011) Trends Immunol. , vol.32 , pp. 603-611
    • Wilke, C.M.1    Bishop, K.2    Fox, D.3    Zou, W.4
  • 44
    • 0032534664 scopus 로고    scopus 로고
    • Nitric oxide synthase plays a signaling role in TCR-triggered apoptotic death
    • Williams, M.S., S. Noguchi, P.A. Henkart, and Y. Osawa. 1998. Nitric oxide synthase plays a signaling role in TCR-triggered apoptotic death. J. Immunol. 161:6526-6531.
    • (1998) J. Immunol. , vol.161 , pp. 6526-6531
    • Williams, M.S.1    Noguchi, S.2    Henkart, P.A.3    Osawa, Y.4
  • 45
    • 0030601323 scopus 로고    scopus 로고
    • Suppression of IFN-gamma production from Listeria monocytogenes-specific T cells by endogenously produced nitric oxide
    • Xiong, H., I. Kawamura, T. Nishibori, and M. Mitsuyama. 1996. Suppression of IFN-gamma production from Listeria monocytogenes-specific T cells by endogenously produced nitric oxide. Cell. Immunol. 172:118-125. http://dx.doi.org/10.1006/cimm.1996.0222
    • (1996) Cell. Immunol. , vol.172 , pp. 118-125
    • Xiong, H.1    Kawamura, I.2    Nishibori, T.3    Mitsuyama, M.4
  • 46
    • 1642304742 scopus 로고    scopus 로고
    • Inhibition of interleukin-12 p40 transcription and NFkappaB activation by nitric oxide in murine macrophages and dendritic cells
    • Xiong, H., C. Zhu, F. Li, R. Hegazi, K. He, M. Babyatsky, A.J. Bauer, and S.E. Plevy. 2004. Inhibition of interleukin-12 p40 transcription and NFkappaB activation by nitric oxide in murine macrophages and dendritic cells. J. Biol. Chem. 279:10776-10783. http://dx.doi.org/10.1074/jbc. M313416200
    • (2004) J. Biol. Chem. , vol.279 , pp. 10776-10783
    • Xiong, H.1    Zhu, C.2    Li, F.3    Hegazi, R.4    He, K.5    Babyatsky, M.6    Bauer, A.J.7    Plevy, S.E.8
  • 49
    • 33846906224 scopus 로고    scopus 로고
    • Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
    • Zheng, Y., D.M. Danilenko, P. Valdez, I. Kasman, J. Eastham-Anderson, J. Wu, and W. Ouyang. 2007. Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature. 445:648-651. http://dx.doi.org/10.1038/nature05505
    • (2007) Nature , vol.445 , pp. 648-651
    • Zheng, Y.1    Danilenko, D.M.2    Valdez, P.3    Kasman, I.4    Eastham-Anderson, J.5    Wu, J.6    Ouyang, W.7
  • 50
    • 34547188748 scopus 로고    scopus 로고
    • IL-6 programs T(H)- 17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
    • Zhou, L., I.I. Ivanov, R. Spolski, R. Min, K. Shenderov, T. Egawa, D.E. Levy, W.J. Leonard, and D.R. Littman. 2007. IL-6 programs T(H)- 17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat. Immunol. 8:967-974. http://dx.doi.org/10.1038/ni1488
    • (2007) Nat. Immunol. , vol.8 , pp. 967-974
    • Zhou, L.1    Ivanov, I.I.2    Spolski, R.3    Min, R.4    Shenderov, K.5    Egawa, T.6    Levy, D.E.7    Leonard, W.J.8    Littman, D.R.9
  • 51
    • 0028941990 scopus 로고
    • Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalomyelitis
    • Zielasek, J., S. Jung, R. Gold, F.Y. Liew, K.V. Toyka, and H.P. Hartung. 1995. Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalomyelitis. J. Neuroimmunol. 58:81-88. http://dx.doi.org/10.1016/0165-5728(94) 00192-
    • (1995) J. Neuroimmunol. , vol.58 , pp. 81-88
    • Zielasek, J.1    Jung, S.2    Gold, R.3    Liew, F.Y.4    Toyka, K.V.5    Hartung, H.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.