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Volumn 191, Issue 3, 2013, Pages 1383-1392

Increased saturated fatty acids in obesity alter resolution of inflammation in part by stimulating prostaglandin production

Author keywords

[No Author keywords available]

Indexed keywords

6 ISOPROPOXY 9 OXO 2 XANTHENECARBOXYLIC ACID; CYCLIC AMP; CYCLOOXYGENASE 2; DP1 PROTEIN; PALMITIC ACID; PROSTAGLANDIN; PROSTAGLANDIN D2; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E2; PROSTANOID; PROSTANOID RECEPTOR; SATURATED FATTY ACID; UNCLASSIFIED DRUG;

EID: 84880651211     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1203369     Document Type: Article
Times cited : (74)

References (59)
  • 1
    • 11844253332 scopus 로고    scopus 로고
    • Prevalence of overweight and obesity among adults with diagnosed diabetes: United states, 1988-1994 and 1999-2002
    • Centers for Disease Control and Prevention (CDC)
    • Centers for Disease Control and Prevention (CDC). 2004. Prevalence of overweight and obesity among adults with diagnosed diabetes: United States, 1988-1994 and 1999-2002. MMWR Morb. Mortal. Wkly. Rep. 53: 1066-1068.
    • (2004) MMWR Morb. Mortal. Wkly. Rep , vol.53 , pp. 1066-1068
  • 2
    • 33745107554 scopus 로고    scopus 로고
    • Mechanisms of disease: Hepatic steatosis in type 2 diabetes: Pathogenesis and clinical relevance
    • Roden, M. 2006. Mechanisms of disease: hepatic steatosis in type 2 diabetes: pathogenesis and clinical relevance. Nat. Clin. Pract. Endocrinol. Metab. 2: 335-348.
    • (2006) Nat. Clin. Pract. Endocrinol. Metab , vol.2 , pp. 335-348
    • Roden, M.1
  • 3
    • 84855353573 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2012 update: A report from the american heart association
    • American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Roger, V. L., A. S. Go, D. M. Lloyd-Jones, E. J. Benjamin, J. D. Berry, W. B. Borden, D. M. Bravata, S. Dai, E. S. Ford, C. S. Fox, et al; American Heart Association Statistics Committee and Stroke Statistics Subcommittee. 2012. Heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation 125: e2-e220.
    • (2012) Circulation , vol.125
    • Roger, V.L.1    Go, A.S.2    Lloyd-Jones, D.M.3    Benjamin, E.J.4    Berry, J.D.5    Borden, W.B.6    Bravata, D.M.7    Dai, S.8    Ford, E.S.9    Fox, C.S.10
  • 4
    • 0036725464 scopus 로고    scopus 로고
    • Interaction between free fatty acids and glucose metabolism
    • Boden, G. 2002. Interaction between free fatty acids and glucose metabolism. Curr. Opin. Clin. Nutr. Metab. Care 5: 545-549.
    • (2002) Curr. Opin. Clin. Nutr. Metab. Care , vol.5 , pp. 545-549
    • Boden, G.1
  • 5
    • 8844255630 scopus 로고    scopus 로고
    • Free fatty acids in obesity and type 2 diabetes: Defining their role in the development of insulin resistance and b-cell dysfunction. Eur
    • Boden, G., and G. I. Shulman. 2002. Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and b-cell dysfunction. Eur. J. Clin. Invest. 32(Suppl. 3): 14-23.
    • (2002) J. Clin. Invest , vol.32 , Issue.SUPPL.. 3 , pp. 14-23
    • Boden, G.1    Shulman, G.I.2
  • 7
    • 0035859801 scopus 로고    scopus 로고
    • Circulating nonesterified fatty acid level as a predictive risk factor for sudden death in the population
    • Jouven, X., M. A. Charles, M. Desnos, and P. Ducimetiére. 2001. Circulating nonesterified fatty acid level as a predictive risk factor for sudden death in the population. Circulation 104: 756-761.
    • (2001) Circulation , vol.104 , pp. 756-761
    • Jouven, X.1    Charles, M.A.2    Desnos, M.3    Ducimetiére, P.4
  • 8
    • 56749164791 scopus 로고    scopus 로고
    • Nutrient sensing and inflammation in metabolic diseases
    • Hotamisligil, G. S., and E. Erbay. 2008. Nutrient sensing and inflammation in metabolic diseases. Nat. Rev. Immunol. 8: 923-934.
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 923-934
    • Hotamisligil, G.S.1    Erbay, E.2
  • 9
    • 33750584214 scopus 로고    scopus 로고
    • Tlr4 links innate immunity and fatty acid-induced insulin resistance
    • Shi, H., M. V. Kokoeva, K. Inouye, I. Tzameli, H. Yin, and J. S. Flier. 2006. TLR4 links innate immunity and fatty acid-induced insulin resistance. J. Clin. Invest. 116: 3015-3025.
    • (2006) J. Clin. Invest , vol.116 , pp. 3015-3025
    • Shi, H.1    Kokoeva, M.V.2    Inouye, K.3    Tzameli, I.4    Yin, H.5    Flier, J.S.6
  • 10
    • 36849005372 scopus 로고    scopus 로고
    • A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via toll-like receptors 2 and 4 and jnk-dependent pathways
    • Nguyen, M. T., S. Favelyukis, A. K. Nguyen, D. Reichart, P. A. Scott, A. Jenn, R. Liu-Bryan, C. K. Glass, J. G. Neels, and J. M. Olefsky. 2007. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J. Biol. Chem. 282: 35279-35292.
    • (2007) J. Biol. Chem , vol.282 , pp. 35279-35292
    • Nguyen, M.T.1    Favelyukis, S.2    Nguyen, A.K.3    Reichart, D.4    Scott, P.A.5    Jenn, A.6    Wedgwood, R.J.7    Glass, C.K.8    Neels, J.G.9    Olefsky, J.M.10
  • 12
    • 79955038882 scopus 로고    scopus 로고
    • Fatty acid-induced nlrp3-Asc inflammasome activation interferes with insulin signaling
    • Wen, H., D. Gris, Y. Lei, S. Jha, L. Zhang, M. T. Huang, W. J. Brickey, and J. P. Ting. 2011. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat. Immunol. 12: 408-415.
    • (2011) Nat. Immunol , Issue.12 , pp. 408-415
    • Wen, H.1    Gris, D.2    Lei, Y.3    Jha, S.4    Zhang, L.5    Huang, M.T.6    Brickey, W.J.7    Ting, J.P.8
  • 13
    • 74049093243 scopus 로고    scopus 로고
    • The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression
    • Tabas, I., A. Tall, and D. Accili. 2010. The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression. Circ. Res. 106: 58-67.
    • (2010) Circ. Res , Issue.106 , pp. 58-67
    • Tabas, I.1    Tall, A.2    Accili, D.3
  • 15
    • 84873050854 scopus 로고    scopus 로고
    • Proresolution therapy for the treatment of delayed healing of diabetic wounds
    • Tang, Y., M. J. Zhang, J. Hellmann, M. Kosuri, A. Bhatnagar, and M. Spite. 2013. Proresolution therapy for the treatment of delayed healing of diabetic wounds. Diabetes 62: 618-627.
    • (2013) Diabetes , vol.62 , pp. 618-627
    • Tang, Y.1    Zhang, M.J.2    Hellmann, J.3    Kosuri, M.4    Bhatnagar, A.5    Spite, M.6
  • 16
    • 0037961580 scopus 로고    scopus 로고
    • Diabetic foot ulcers
    • Jeffcoate, W. J., and K. G. Harding. 2003. Diabetic foot ulcers. Lancet 361: 1545-1551.
    • (2003) Lancet , vol.361 , pp. 1545-1551
    • Jeffcoate, W.J.1    Harding, K.G.2
  • 17
    • 84865297442 scopus 로고    scopus 로고
    • The inflammation highway: Metabolism accelerates inflammatory traffic in obesity
    • Johnson, A. R., J. J. Milner, and L. Makowski. 2012. The inflammation highway: metabolism accelerates inflammatory traffic in obesity. Immunol. Rev. 249: 218-238.
    • (2012) Immunol. Rev , Issue.249 , pp. 218-238
    • Johnson, A.R.1    Milner, J.J.2    Makowski, L.3
  • 18
    • 42649089790 scopus 로고    scopus 로고
    • Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators
    • Serhan, C. N., N. Chiang, and T. E. Van Dyke. 2008. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat. Rev. Immunol. 8: 349-361.
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 349-361
    • Serhan, C.N.1    Chiang, N.2    Van Dyke, T.E.3
  • 19
    • 78650695097 scopus 로고    scopus 로고
    • Old and new generation lipid mediators in acute inflammation and resolution
    • Stables, M. J., and D.W. Gilroy. 2011. Old and new generation lipid mediators in acute inflammation and resolution. Prog. Lipid Res. 50: 35-51.
    • (2011) Prog. Lipid Res , Issue.50 , pp. 35-51
    • Stables, M.J.1    Gilroy, D.W.2
  • 20
    • 34748817976 scopus 로고    scopus 로고
    • Membrane prostaglandin e synthase-1: A novel therapeutic target
    • Samuelsson, B., R. Morgenstern, and P. J. Jakobsson. 2007. Membrane prostaglandin E synthase-1: a novel therapeutic target. Pharmacol. Rev. 59: 207-224.
    • (2007) Pharmacol. Rev , vol.59 , pp. 207-224
    • Samuelsson, B.1    Morgenstern, R.2    Jakobsson, P.J.3
  • 21
    • 77950365906 scopus 로고    scopus 로고
    • Nonresolving inflammation
    • Nathan, C., and A. Ding. 2010. Nonresolving inflammation. Cell 140: 871-882.
    • (2010) Cell , vol.140 , pp. 871-882
    • Nathan, C.1    Ding, A.2
  • 23
    • 80755180853 scopus 로고    scopus 로고
    • Beginnings of a good apoptotic meal: The find-me and eat-me signaling pathways
    • Ravichandran, K. S. 2011. Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways. Immunity 35: 445-455.
    • (2011) Immunity , vol.35 , pp. 445-455
    • Ravichandran, K.S.1
  • 24
    • 84862883553 scopus 로고    scopus 로고
    • Information processing during phagocytosis
    • Underhill, D. M., and H. S. Goodridge. 2012. Information processing during phagocytosis. Nat. Rev. Immunol. 12: 492-502.
    • (2012) Nat. Rev. Immunol , Issue.12 , pp. 492-502
    • Underhill, D.M.1    Goodridge, H.S.2
  • 25
    • 80052185387 scopus 로고    scopus 로고
    • Metabolomics-lipidomics of eicosanoids and docosanoids generated by phagocytes
    • Chapter 14: Unit 14.26
    • Yang, R., N. Chiang, S. F. Oh, and C. N. Serhan. 2011. Metabolomics-lipidomics of eicosanoids and docosanoids generated by phagocytes. Curr. Protoc. Immunol. Chapter 14: Unit 14.26.
    • (2011) Curr. Protoc. Immunol
    • Yang, R.1    Chiang, N.2    Oh, S.F.3    Serhan, C.N.4
  • 26
    • 0021908138 scopus 로고
    • Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide
    • Haslett, C., L. A. Guthrie, M. M. Kopaniak, R. B. Johnston, Jr., and P. M. Henson. 1985. Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide. Am. J. Pathol. 119: 101-110.
    • (1985) Am. J. Pathol , vol.119 , pp. 101-110
    • Haslett, C.1    Guthrie, L.A.2    Kopaniak, M.M.3    Johnston Jr., R.B.4    Henson, P.M.5
  • 27
    • 72949092179 scopus 로고    scopus 로고
    • Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet
    • Li, S., Y. Sun, C. P. Liang, E. B. Thorp, S. Han, A. W. Jehle, V. Saraswathi, B. Pridgen, J. E. Kanter, R. Li, et al. 2009. Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet. Circ. Res. 105: 1072-1082.
    • (2009) Circ. Res , vol.105 , pp. 1072-1082
    • Li, S.1    Sun, Y.2    Liang, C.P.3    Thorp, E.B.4    Han, S.5    Jehle, A.W.6    Saraswathi, V.7    Pridgen, B.8    Kanter, J.E.9    Li, R.10
  • 29
    • 72449150930 scopus 로고    scopus 로고
    • Neutrophil apoptosis: A target for enhancing the resolution of inflammation
    • Filep, J. G., and D. El Kebir. 2009. Neutrophil apoptosis: a target for enhancing the resolution of inflammation. J. Cell. Biochem. 108: 1039-1046.
    • (2009) J. Cell. Biochem , vol.108 , pp. 1039-1046
    • Filep, J.G.1    El Kebir, D.2
  • 30
    • 0035036669 scopus 로고    scopus 로고
    • Role of extracellular signal-regulated kinase and phosphatidylinositol-3 kinase in chemoattractant and lps delay of constitutive neutrophil apoptosis
    • Klein, J. B., A. Buridi, P. Y. Coxon, M. J. Rane, T. Manning, R. Kettritz, and K. R. McLeish. 2001. Role of extracellular signal-regulated kinase and phosphatidylinositol-3 kinase in chemoattractant and LPS delay of constitutive neutrophil apoptosis. Cell. Signal. 13: 335-343.
    • (2001) Cell. Signal , vol.13 , pp. 335-343
    • Klein, J.B.1    Buridi, A.2    Coxon, P.Y.3    Rane, M.J.4    Manning, T.5    Kettritz, R.6    McLeish, K.R.7
  • 32
    • 4444262310 scopus 로고    scopus 로고
    • Pharmacology and signaling of prostaglandin receptors: Multiple roles in inflammation and immune modulation
    • Hata, A. N., and R. M. Breyer. 2004. Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation. Pharmacol. Ther. 103: 147-166.
    • (2004) Pharmacol. Ther , vol.103 , pp. 147-166
    • Hata, A.N.1    Breyer, R.M.2
  • 34
    • 2942722569 scopus 로고    scopus 로고
    • Prostaglandin e2 inhibits alveolar macrophage phagocytosis through an e-prostanoid 2 receptor-mediated increase in intracellular cyclic amp
    • Aronoff, D. M., C. Canetti, and M. Peters-Golden. 2004. Prostaglandin E2 inhibits alveolar macrophage phagocytosis through an E-prostanoid 2 receptor-mediated increase in intracellular cyclic AMP. J. Immunol. 173: 559-565.
    • (2004) J. Immunol , vol.173 , pp. 559-565
    • Aronoff, D.M.1    Canetti, C.2    Roose-Girma, M.3
  • 36
    • 0036320896 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic cells by macrophages from nod mice is reduced
    • O'Brien, B. A., Y. Huang, X. Geng, J. P. Dutz, and D. T. Finegood. 2002. Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced. Diabetes 51: 2481-2488.
    • (2002) Diabetes , vol.51 , pp. 2481-2488
    • O'Brien, B.A.1    Huang, Y.2    Geng, X.3    Dutz, J.P.4    Finegood, D.T.5
  • 38
    • 80051842679 scopus 로고    scopus 로고
    • Phagocytic activity is impaired in type 2 diabetes mellitus and increases after metabolic improvement
    • Lecube, A., G. Pachón, J. Petriz, C. Hernández, and R. Simó . 2011. Phagocytic activity is impaired in type 2 diabetes mellitus and increases after metabolic improvement. PLoS ONE 6: e23366.
    • (2011) PLoS ONE , vol.6
    • Lecube, A.1    Pachón, G.2    Petriz, J.3    Hernández, C.4    Wedgwood, R.J.5
  • 41
    • 0021211061 scopus 로고
    • Alterations in fc receptor function of macrophages from streptozotocin-induced diabetic rats
    • Abrass, C. K., and M. Hori. 1984. Alterations in Fc receptor function of macrophages from streptozotocin-induced diabetic rats. J. Immunol. 133: 1307-1312.
    • (1984) J. Immunol , vol.133 , pp. 1307-1312
    • Abrass, C.K.1    Hori, M.2
  • 42
    • 0035907302 scopus 로고    scopus 로고
    • Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through toll-like receptor 4
    • Lee, J. Y., K. H. Sohn, S. H. Rhee, and D. Hwang. 2001. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J. Biol. Chem. 276: 16683-16689.
    • (2001) J. Biol. Chem , vol.276 , pp. 16683-16689
    • Lee, J.Y.1    Sohn, K.H.2    Rhee, S.H.3    Hwang, D.4
  • 44
    • 79956290893 scopus 로고    scopus 로고
    • Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer
    • Dong, L., A. J. Vecchio, N. P. Sharma, B. J. Jurban, M. G. Malkowski, and W. L. Smith. 2011. Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer. J. Biol. Chem. 286: 19035-19046.
    • (2011) J. Biol. Chem , vol.286 , pp. 19035-19046
    • Dong, L.1    Vecchio, A.J.2    Sharma, N.P.3    Jurban, B.J.4    Malkowski, M.G.5    Smith, W.L.6
  • 45
    • 65649108576 scopus 로고    scopus 로고
    • Cyclooxygenase allosterism, fatty acid-mediated cross-talk between monomers of cyclooxygenase homodimers
    • Yuan, C., R. S. Sidhu, D. V. Kuklev, Y. Kado, M.Wada, I. Song, andW. L. Smith. 2009. Cyclooxygenase allosterism, fatty acid-mediated cross-talk between monomers of cyclooxygenase homodimers. J. Biol. Chem. 284: 10046-10055.
    • (2009) J. Biol. Chem , vol.284 , pp. 10046-10055
    • Yuan, C.1    Sidhu, R.S.2    Kuklev, D.V.3    Kado, Y.4    Wada, M.5    Song, I.6    Smith, W.L.7
  • 47
    • 11844252117 scopus 로고    scopus 로고
    • Cutting edge: Macrophage inhibition by cyclic amp (camp): Differential roles of protein kinase a and exchange protein directly activated by camp-1
    • Aronoff, D. M., C. Canetti, C. H. Serezani, M. Luo, and M. Peters-Golden. 2005. Cutting edge: macrophage inhibition by cyclic AMP (cAMP): differential roles of protein kinase A and exchange protein directly activated by cAMP-1. J. Immunol. 174: 595-599.
    • (2005) J. Immunol , vol.174 , pp. 595-599
    • Aronoff, D.M.1    Canetti, C.2    Serezani, C.H.3    Luo, M.4    Roose-Girma, M.5
  • 48
    • 33744899583 scopus 로고    scopus 로고
    • The cyclic amp-epac1-rap1 pathway is dissociated from regulation of effector functions in monocytes but acquires immunoregulatory function in mature macrophages
    • Bryn, T., M. Mahic, J. M. Enserink, F. Schwede, E. M. Aandahl, and K. Taskén. 2006. The cyclic AMP-Epac1-Rap1 pathway is dissociated from regulation of effector functions in monocytes but acquires immunoregulatory function in mature macrophages. J. Immunol. 176: 7361-7370.
    • (2006) J. Immunol , vol.176 , pp. 7361-7370
    • Bryn, T.1    Mahic, M.2    Enserink, J.M.3    Schwede, F.4    Aandahl, E.M.5    Taskén, K.6
  • 49
    • 0033894983 scopus 로고    scopus 로고
    • Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: Prolonged persistence of neutrophils and macrophages during the late phase of repair
    • Wetzler, C., H. Kämpfer, B. Stallmeyer, J. Pfeilschifter, and S. Frank. 2000. Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: prolonged persistence of neutrophils and macrophages during the late phase of repair. J. Invest. Dermatol. 115: 245-253.
    • (2000) J. Invest. Dermatol , vol.115 , pp. 245-253
    • Wetzler, C.1    Kämpfer, H.2    Stallmeyer, B.3    Pfeilschifter, J.4    Frank, S.5
  • 53
    • 0034916569 scopus 로고    scopus 로고
    • Lipid mediator class switching during acute inflammation: Signals in resolution
    • Levy, B. D., C. B. Clish, B. Schmidt, K. Gronert, and C. N. Serhan. 2001. Lipid mediator class switching during acute inflammation: signals in resolution. Nat. Immunol. 2: 612-619.
    • (2001) Nat. Immunol , vol.2 , pp. 612-619
    • Levy, B.D.1    Clish, C.B.2    Schmidt, B.3    Gronert, K.4    Serhan, C.N.5
  • 54
    • 34250357688 scopus 로고    scopus 로고
    • Resolvin e1 and protectin d1 activate inflammation-resolution programmes
    • Schwab, J. M., N. Chiang, M. Arita, and C. N. Serhan. 2007. Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature 447: 869-874.
    • (2007) Nature , vol.447 , pp. 869-874
    • Schwab, J.M.1    Chiang, N.2    Arita, M.3    Serhan, C.N.4
  • 55
    • 0036080959 scopus 로고    scopus 로고
    • Lipoxins induce actin reorganization in monocytes and macrophages but not in neutrophils: Differential involvement of rho gtpases
    • Maderna, P., D. C. Cottell, G. Berlasconi, N. A. Petasis, H. R. Brady, and C. Godson. 2002. Lipoxins induce actin reorganization in monocytes and macrophages but not in neutrophils: differential involvement of rho GTPases. Am. J. Pathol. 160: 2275-2283.
    • (2002) Am. J. Pathol , vol.160 , pp. 2275-2283
    • Maderna, P.1    Cottell, D.C.2    Berlasconi, G.3    Petasis, N.A.4    Brady, H.R.5    Godson, C.6
  • 58
    • 84880510658 scopus 로고    scopus 로고
    • Obesity and respiratory infections: Does excess adiposity weigh down host defense?
    • Mancuso, P. 2013. Obesity and respiratory infections: does excess adiposity weigh down host defense? Pulm. Pharmacol. Ther. 26: 412-419.
    • (2013) Pulm. Pharmacol. Ther , Issue.26 , pp. 412-419
    • Mancuso, P.1


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