Detection of γ-H2AX, a biomarker for DNA double-strand breaks, in urinary bladders of N-butyl-N-(4-Hydroxybutyl)-nitrosamine- treated rats

Journal of Toxicologic Pathology

Volumn 26, Issue 2, 2013, Pages 215-221

  Toyoda, Takeshi ^a   Akagi, Jun ichi ^a   Cho, Young Man ^a   Mizuta, Yasuko ^a   Onami, Saeko ^a   Suzuki, Isamu ^a   Ogawa, Kumiko ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

H2AX; DNA repair; Double strand breaks; N butyl N (4 hydroxybutyl) nitrosamine; Urinary bladder

Indexed keywords

EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; GAMMA HISTONE H2AX; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MRE11 PROTEIN; N BUTYL N (4 HYDROXYBUTYL)NITROSAMINE; NUCLEAR PROTEIN; PROTEIN APE1; PROTEIN DDB1; PROTEIN MLH1; PROTEIN MSH6; PROTEIN SMC1; PROTEIN TREX1; RAD18 PROTEIN; UNCLASSIFIED DRUG; XRCC1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CANCER; BLADDER CARCINOGENESIS; BLADDER EPITHELIUM; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EARLY DIAGNOSIS; EPITHELIUM CELL; GENOTOXICITY; HISTONE PHOSPHORYLATION; HISTOPATHOLOGY; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; UROTHELIUM;

EID: 84880644480     PISSN: 09149198     EISSN: None     Source Type: Journal    
DOI: 10.1293/tox.26.215     Document Type: Article

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