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Volumn 30, Issue 3, 2013, Pages 1030-1034

Perspective: Opportunities in recalcitrant, rare and neglected tumors

Author keywords

Neglected tumors; Pancreatic cancer; Rare tumors; Recalicitrant tumors; Sarcoma small cell lung cancer

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; CASPASE 10; CISPLATIN; DEATH RECEPTOR 5; ERLOTINIB; ETOPOSIDE; FAS ANTIGEN; FAS LIGAND; GEMCITABINE; MICRORNA; TOPOTECAN;

EID: 84880627913     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2581     Document Type: Review
Times cited : (9)

References (51)
  • 4
    • 84902042512 scopus 로고    scopus 로고
    • Comparison of progression-free survival (PFS) and tumor response as endpoints for predicting overall survival (OS) in untreated extensive-stage small cell lung cancer (ED-SCLC): Findings based on North Central Cancer Treatment Group (NCCTG) trials
    • Foster NR, Qi Y, Krook JE, Kugler JW, Kuross SA, Jett JR, Molina JR, Schild SE, Adjei AA and Mandrekar SJ: Comparison of progression-free survival (PFS) and tumor response as endpoints for predicting overall survival (OS) in untreated extensive-stage small cell lung cancer (ED-SCLC): findings based on North Central Cancer Treatment Group (NCCTG) trials. J Clin Oncol 27 (Suppl 15): 8085, 2009.
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL. 15 , pp. 8085
    • Foster, N.R.1    Qi, Y.2    Krook, J.E.3    Kugler, J.W.4    Kuross, S.A.5    Jett, J.R.6    Molina, J.R.7    Schild, S.E.8    Adjei, A.A.9    Mandrekar, S.J.10
  • 8
    • 84858602107 scopus 로고    scopus 로고
    • Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma
    • Provenzano PP, Cuevas C, Chang AE, Goel VK, Von Hoff DD and Hingorani SR: Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma. Cancer Cell 21: 418-429, 2012.
    • (2012) Cancer Cell , vol.21 , pp. 418-429
    • Provenzano, P.P.1    Cuevas, C.2    Chang, A.E.3    Goel, V.K.4    Von Hoff, D.D.5    Hingorani, S.R.6
  • 9
    • 77951755278 scopus 로고    scopus 로고
    • Pancreatic cancer
    • Hidalgo M: Pancreatic cancer. N Engl J Med 362: 1605-1617, 2010.
    • (2010) N Engl J Med , vol.362 , pp. 1605-1617
    • Hidalgo, M.1
  • 10
    • 84860658205 scopus 로고    scopus 로고
    • Searching for molecular targets in sarcoma
    • Teicher BA: Searching for molecular targets in sarcoma. Biochem Pharmacol 84: 1-10, 2012.
    • (2012) Biochem Pharmacol , vol.84 , pp. 1-10
    • Teicher, B.A.1
  • 12
    • 70649099227 scopus 로고    scopus 로고
    • Twenty-seven years of phase III trials for patients with extensive disease small-cell lung cancer: Disappointing results
    • Oze I, Hotta K, Kiura K, Ochi N, Takigawa N, Fujiwara Y, Tabata M and Tanimoto M: Twenty-seven years of phase III trials for patients with extensive disease small-cell lung cancer: disappointing results. PLoS One 4: e7835, 2009.
    • (2009) PLoS One , vol.4
    • Oze, I.1    Hotta, K.2    Kiura, K.3    Ochi, N.4    Takigawa, N.5    Fujiwara, Y.6    Tabata, M.7    Tanimoto, M.8
  • 13
    • 0023267965 scopus 로고
    • Myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course
    • Johnson BE, Ihde DC, Makuch RW, Gazdar AF, Carney DN, Loe H, Russell E, Nau MN and Minna JD: myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course. J Clin Invest 79: 1629-1634, 1987.
    • (1987) J Clin Invest , vol.79 , pp. 1629-1634
    • Johnson, B.E.1    Ihde, D.C.2    Makuch, R.W.3    Gazdar, A.F.4    Carney, D.N.5    Loe, H.6    Russell, E.7    Nau, M.N.8    Minna, J.D.9
  • 17
    • 0141834796 scopus 로고    scopus 로고
    • Hedgehog signaling: Progenitor phenotype in small cell lung cancer
    • Watkins DN, Berman DM and Baylin SB: Hedgehog signaling: progenitor phenotype in small cell lung cancer. Cell Cycle 2: 196-198, 2003.
    • (2003) Cell Cycle , vol.2 , pp. 196-198
    • Watkins, D.N.1    Berman, D.M.2    Baylin, S.B.3
  • 18
    • 77954405026 scopus 로고    scopus 로고
    • The molecular pathogenesis of small cell lung cancer
    • D'Angelo SP and Pietanza MC: The molecular pathogenesis of small cell lung cancer. Cancer Biol Ther 10: 1-10, 2010.
    • (2010) Cancer Biol Ther , vol.10 , pp. 1-10
    • D'Angelo, S.P.1    Pietanza, M.C.2
  • 19
    • 79951529195 scopus 로고    scopus 로고
    • Integrated metabolome and transriptome analysis of the NCI60 dataset
    • Su G, Burant CF, Beecher CW, Athey BD and Meng F: Integrated metabolome and transriptome analysis of the NCI60 dataset. BMC Bioinformatics 12 (Suppl 1): S36, 2011.
    • (2011) BMC Bioinformatics , vol.12 , Issue.SUPPL. 1
    • Su, G.1    Burant, C.F.2    Beecher, C.W.3    Athey, B.D.4    Meng, F.5
  • 22
    • 34548091013 scopus 로고    scopus 로고
    • Anticancer medicines in development: Assessment of bioactivity profiles within the National Cancer Institute anticancer screening data
    • Covell DG, Huang R and Wallqvist A: Anticancer medicines in development: assessment of bioactivity profiles within the National Cancer Institute anticancer screening data. Mol Cancer Ther 6: 2261-2270, 2007.
    • (2007) Mol Cancer Ther , vol.6 , pp. 2261-2270
    • Covell, D.G.1    Huang, R.2    Wallqvist, A.3
  • 23
    • 33749011163 scopus 로고    scopus 로고
    • The NCI60 human tumor cell line anticancer drug screen
    • Shoemaker RH: The NCI60 human tumor cell line anticancer drug screen. Nat Rev Cancer 6: 813-823, 2006.
    • (2006) Nat Rev Cancer , vol.6 , pp. 813-823
    • Shoemaker, R.H.1
  • 24
    • 77955036485 scopus 로고    scopus 로고
    • Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1
    • Fer ND, Shoemaker RH and Monks A: Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1. J Exp Clin Cancer Res 29: 91, 2010.
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 91
    • Fer, N.D.1    Shoemaker, R.H.2    Monks, A.3
  • 27
    • 70349334004 scopus 로고    scopus 로고
    • Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts
    • Monks A, Hose C, Pezzoli P, Kondapaka S, Vasant G, Petersen KD, Sehested M, Monteforte J and Shoemaker RH: Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts. Anticancer Drugs 20: 682-692, 2009.
    • (2009) Anticancer Drugs , vol.20 , pp. 682-692
    • Monks, A.1    Hose, C.2    Pezzoli, P.3    Kondapaka, S.4    Vasant, G.5    Petersen, K.D.6    Sehested, M.7    Monteforte, J.8    Shoemaker, R.H.9
  • 29
    • 33745957772 scopus 로고    scopus 로고
    • Drug-induced expression of nonsteroidal anti-inflammatory drug-activated gene/macrophage inhibitory cytokine-1/prostate-derived factor, a putative suppressor, inhibits tumor growth
    • Martinez JM, Sali T, Okazaki R, Anna C, Hollingshead M, Hose C, Monks A, Walker NJ, Baek SJ and Eling TE: Drug-induced expression of nonsteroidal anti-inflammatory drug-activated gene/macrophage inhibitory cytokine-1/prostate- derived factor, a putative suppressor, inhibits tumor growth. J Pharmacol Exp Ther 18: 899-906, 2006.
    • (2006) J Pharmacol Exp Ther , vol.18 , pp. 899-906
    • Martinez, J.M.1    Sali, T.2    Okazaki, R.3    Anna, C.4    Hollingshead, M.5    Hose, C.6    Monks, A.7    Walker, N.J.8    Baek, S.J.9    Eling, T.E.10
  • 31
    • 77956286559 scopus 로고    scopus 로고
    • Aminoflavone, a ligand of the aryl hydrocarbon receptor, inhibits HIF-1α expression in an AhR-independent fashion
    • Terzuoli E, Puppo M, Rapisarda A, Uranchimeg B, Cao L, Burger AM, Ziche M and Melillo G: Aminoflavone, a ligand of the aryl hydrocarbon receptor, inhibits HIF-1α expression in an AhR-independent fashion. Cancer Res 70: 6837-6848, 2010.
    • (2010) Cancer Res , vol.70 , pp. 6837-6848
    • Terzuoli, E.1    Puppo, M.2    Rapisarda, A.3    Uranchimeg, B.4    Cao, L.5    Burger, A.M.6    Ziche, M.7    Melillo, G.8
  • 33
    • 84863422466 scopus 로고    scopus 로고
    • Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia
    • Rapisarda A and Melillo G: Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia. Nat Rev Clin Oncol 9: 378-390, 2012.
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 378-390
    • Rapisarda, A.1    Melillo, G.2
  • 34
    • 84860792754 scopus 로고    scopus 로고
    • Role of the VEGF/VEGFR axis in cancer biology and therapy
    • Rapisarda A and Melillo G: Role of the VEGF/VEGFR axis in cancer biology and therapy. Adv Cancer Res 114: 237-267, 2012.
    • (2012) Adv Cancer Res , vol.114 , pp. 237-267
    • Rapisarda, A.1    Melillo, G.2
  • 35
    • 84880610232 scopus 로고    scopus 로고
    • Combination strategies targeting hypoxia inducible factor 1 (HIF-1) for cancer therapy
    • Bagley RG (ed). Springer Science+Business Media, LLC
    • Rapisarda A and Melillo G: Combination strategies targeting hypoxia inducible factor 1 (HIF-1) for cancer therapy. In: The Tumor Microenvironment. Series: Cancer Drug Discovery and Development. Bagley RG (ed). Springer Science+Business Media, LLC 2010.
    • (2010) The Tumor Microenvironment. Series: Cancer Drug Discovery and Development
    • Rapisarda, A.1    Melillo, G.2
  • 36
    • 72849115544 scopus 로고    scopus 로고
    • Development of HIF-1 inhibitors for cancer therapy
    • Onnis B, Rapisarda A and Melillo G: Development of HIF-1 inhibitors for cancer therapy. J Cell Mol Med 13: 2780-2786, 2009.
    • (2009) J Cell Mol Med , vol.13 , pp. 2780-2786
    • Onnis, B.1    Rapisarda, A.2    Melillo, G.3
  • 37
    • 74849127957 scopus 로고    scopus 로고
    • Antiangiogenic agents and HIF-1 inhibitors meet at the crossroads
    • Rapisarda A, Shoemaker RH and Melillo G: Antiangiogenic agents and HIF-1 inhibitors meet at the crossroads. Cell Cycle 8: 4040-4043, 2009.
    • (2009) Cell Cycle , vol.8 , pp. 4040-4043
    • Rapisarda, A.1    Shoemaker, R.H.2    Melillo, G.3
  • 38
    • 67349129399 scopus 로고    scopus 로고
    • Role of the hypoxic tumor microenvironment in the resistance to anti-angiogenic therapies
    • Rapisarda A and Melillo G: Role of the hypoxic tumor microenvironment in the resistance to anti-angiogenic therapies. Drug Resist Updat 12: 74-80, 2009.
    • (2009) Drug Resist Updat , vol.12 , pp. 74-80
    • Rapisarda, A.1    Melillo, G.2
  • 39
    • 62349092879 scopus 로고    scopus 로고
    • ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC
    • Stockwin LH, Yu SX, Stotler H, Hollingshead MG and Newton DL: ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC. BMC Cancer 9: 63, 2009.
    • (2009) BMC Cancer , vol.9 , pp. 63
    • Stockwin, L.H.1    Yu, S.X.2    Stotler, H.3    Hollingshead, M.G.4    Newton, D.L.5
  • 40
    • 68249142819 scopus 로고    scopus 로고
    • Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction
    • Stockwin LH, Han B, Yu SX, Hollingshead MG, ElSohly MA, Gul G, Slade D, Galal A and Newton DL: Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction. Int J Cancer 125: 1266-1275, 2009.
    • (2009) Int J Cancer , vol.125 , pp. 1266-1275
    • Stockwin, L.H.1    Han, B.2    Yu, S.X.3    Hollingshead, M.G.4    Elsohly, M.A.5    Gul, G.6    Slade, D.7    Galal, A.8    Newton, D.L.9
  • 42
    • 77955443849 scopus 로고    scopus 로고
    • Proteomic analysis of nuclei isolated from cancer cell lines treated with indenoisoquinoline NSC 724998, a novel topoisomerase i inhibitor
    • Han B, Stockwin LH, Hancock C, Yu SX, Hollingshead MG and Newton DL: Proteomic analysis of nuclei isolated from cancer cell lines treated with indenoisoquinoline NSC 724998, a novel topoisomerase I inhibitor. J Proteome Res 9: 4016-4027, 2010.
    • (2010) J Proteome Res , vol.9 , pp. 4016-4027
    • Han, B.1    Stockwin, L.H.2    Hancock, C.3    Yu, S.X.4    Hollingshead, M.G.5    Newton, D.L.6
  • 48
    • 58549110422 scopus 로고    scopus 로고
    • Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity
    • Galal AM, Gul W, Slade D, Ross SA, Feng S, Hollingshead MG, Alley MC, Kaur G and ElSohly MA: Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity. Bioorg Med Chem 17: 741-751, 2009.
    • (2009) Bioorg Med Chem , vol.17 , pp. 741-751
    • Galal, A.M.1    Gul, W.2    Slade, D.3    Ross, S.A.4    Feng, S.5    Hollingshead, M.G.6    Alley, M.C.7    Kaur, G.8    ElSohly, M.A.9
  • 51
    • 34748854847 scopus 로고    scopus 로고
    • Identification of a bis-guanylhydrazone [4,4'-diacetyldiphenylurea-bis (guanylhydrazone); NSC 109555] as a novel chemotype for inhibition of Ckh2 kinase
    • Jobson AG, Cardellina JH, Scudiero D, Kondapaka S, Zhang H, Kim H, Shoemaker R and Pommier Y: Identification of a bis-guanylhydrazone [4,4'-diacetyldiphenylurea-bis (guanylhydrazone); NSC 109555] as a novel chemotype for inhibition of Ckh2 kinase. Mol Pharmacol 72: 876-884, 2007.
    • (2007) Mol Pharmacol , vol.72 , pp. 876-884
    • Jobson, A.G.1    Cardellina, J.H.2    Scudiero, D.3    Kondapaka, S.4    Zhang, H.5    Kim, H.6    Shoemaker, R.7    Pommier, Y.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.