Trypsin-Mediated 18O/16O labeling for biomarker discovery

Methods in Molecular Biology

Volumn 1002, Issue , 2013, Pages 133-149

  Ye, Xiaoying ^a   Chan, King C ^b   Prieto, Darue A ^a   Luke, Brian T ^a   Johann Jr , Donald J ^c   Stockwin, Luke H ^a   Newton, Dianne L ^a   Blonder, Josip ^a  

^a FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^b Laboratory of Proteomics and Analytical Technologies   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

18O 16O stable isotope labeling; Hypoxia biomarker; Mass spectrometry; Melanoma; Quantitative shotgun proteomics

Indexed keywords

BIOLOGICAL MARKER; MEMBRANE PROTEIN; OXYGEN; OXYGEN 18; TRYPSIN; PROTEIN; TUMOR MARKER;

ANIMAL CELL; BODY FLUID; CANCER CELL CULTURE; CATION EXCHANGE; CELL HYPOXIA; DRUG MIXTURE; HYPOXIA; LIQUID CHROMATOGRAPHY; MELANOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEOMICS; REVERSED PHASE LIQUID CHROMATOGRAPHY; REVIEW; SOLUBILIZATION; TANDEM MASS SPECTROMETRY; ARTICLE; CELL MEMBRANE; CHEMISTRY; HUMAN; ISOTOPE LABELING; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; TUMOR CELL LINE; PROCEDURES;

CELL HYPOXIA; CELL LINE, TUMOR; CELL MEMBRANE; CHROMATOGRAPHY, LIQUID; HUMANS; ISOTOPE LABELING; MASS SPECTROMETRY; MELANOMA; OXYGEN ISOTOPES; PROTEINS; PROTEOMICS; TRYPSIN; TUMOR MARKERS, BIOLOGICAL;

EID: 84880602589     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-360-2_12     Document Type: Review

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