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Volumn 12, Issue 8, 2013, Pages 605-611

ATM-deficient human neural stem cells as an in vitro model system to study neurodegeneration

Author keywords

ATM; DNA damage response; Hypoxia; IPS cells; Neural stem cells; Neurodegeneration

Indexed keywords

ATM PROTEIN;

EID: 84880624619     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2013.04.013     Document Type: Article
Times cited : (18)

References (50)
  • 1
    • 3242876404 scopus 로고    scopus 로고
    • Ataxia-telangiectasia, an evolving phenotype
    • Chun H.H., Gatti R.A. Ataxia-telangiectasia, an evolving phenotype. DNA Repair 2004, 3:1187-1196.
    • (2004) DNA Repair , vol.3 , pp. 1187-1196
    • Chun, H.H.1    Gatti, R.A.2
  • 2
    • 84856866360 scopus 로고    scopus 로고
    • ATM and the molecular pathogenesis of ataxia telangiectasia
    • McKinnon.P.J. ATM and the molecular pathogenesis of ataxia telangiectasia. Annu. Rev. Pathol. 2012, 7:303-321.
    • (2012) Annu. Rev. Pathol. , vol.7 , pp. 303-321
    • McKinnon, P.J.1
  • 3
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: safeguarding genome integrity
    • Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 2003, 3:155-168.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 4
    • 34247483506 scopus 로고    scopus 로고
    • ATM activation and DNA damage response
    • Lavin M.F., Kozlov S. ATM activation and DNA damage response. Cell Cycle 2007, 6:931-942.
    • (2007) Cell Cycle , vol.6 , pp. 931-942
    • Lavin, M.F.1    Kozlov, S.2
  • 5
    • 52449114574 scopus 로고    scopus 로고
    • Ataxia-telangiectasia. From a rare disorder to a paradigm for cell signalling and cancer
    • Lavin M.F. Ataxia-telangiectasia. From a rare disorder to a paradigm for cell signalling and cancer. Nat. Rev. Mol. Cell Biol. 2008, 9:759-769.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 759-769
    • Lavin, M.F.1
  • 6
    • 34247159940 scopus 로고    scopus 로고
    • Responding to DNA double strand breaks in the nervous system
    • Lee Y., McKinnon.P.J. Responding to DNA double strand breaks in the nervous system. Neuroscience 2007, 145:1365-1374.
    • (2007) Neuroscience , vol.145 , pp. 1365-1374
    • Lee, Y.1    McKinnon, P.J.2
  • 7
    • 44949085340 scopus 로고    scopus 로고
    • The role of the DNA damage response in neuronal development, organization and maintenance
    • Barzilai A., Biton S., Shiloh Y. The role of the DNA damage response in neuronal development, organization and maintenance. DNA Repair 2008, 7:1010-1027.
    • (2008) DNA Repair , vol.7 , pp. 1010-1027
    • Barzilai, A.1    Biton, S.2    Shiloh, Y.3
  • 8
    • 0036012789 scopus 로고    scopus 로고
    • ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage
    • Barzilai A., Rotman G., Shiloh Y. ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage. DNA Repair 2002, 1:3-25.
    • (2002) DNA Repair , vol.1 , pp. 3-25
    • Barzilai, A.1    Rotman, G.2    Shiloh, Y.3
  • 9
    • 27944476980 scopus 로고    scopus 로고
    • ATM deficiency induces oxidative stress and endoplasmic reticulum stress in astrocytes
    • Liu N., Stoica G., Yan M., Scofield V.L., Qiang W., Lynn W.S., Wong P.K. ATM deficiency induces oxidative stress and endoplasmic reticulum stress in astrocytes. Lab. Invest. 2005, 85:1471-1480.
    • (2005) Lab. Invest. , vol.85 , pp. 1471-1480
    • Liu, N.1    Stoica, G.2    Yan, M.3    Scofield, V.L.4    Qiang, W.5    Lynn, W.S.6    Wong, P.K.7
  • 10
    • 3442902484 scopus 로고    scopus 로고
    • Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in ATM-deficient mice
    • Reliene R., Fischer E., Schiestl R.H. Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in ATM-deficient mice. Cancer Res. 2004, 64:5148-5153.
    • (2004) Cancer Res. , vol.64 , pp. 5148-5153
    • Reliene, R.1    Fischer, E.2    Schiestl, R.H.3
  • 11
    • 33646764926 scopus 로고    scopus 로고
    • N-acetylcysteine selectively protects cerebellar granule cells from 4-hydroxynonenal-induced cell death
    • Arakawa M., Ushimaru N., Osada N., Oda T., Ishige K., Ito Y. N-acetylcysteine selectively protects cerebellar granule cells from 4-hydroxynonenal-induced cell death. Neurosci. Res. 2006, 55:255-263.
    • (2006) Neurosci. Res. , vol.55 , pp. 255-263
    • Arakawa, M.1    Ushimaru, N.2    Osada, N.3    Oda, T.4    Ishige, K.5    Ito, Y.6
  • 14
    • 14944346310 scopus 로고    scopus 로고
    • Loss of neuronal cell cycle control in ataxia-telangiectasia: a unified disease mechanism
    • Yang Y., Herrup K. Loss of neuronal cell cycle control in ataxia-telangiectasia: a unified disease mechanism. J. Neurosci. 2005, 25:2522-2529.
    • (2005) J. Neurosci. , vol.25 , pp. 2522-2529
    • Yang, Y.1    Herrup, K.2
  • 15
    • 33845742491 scopus 로고    scopus 로고
    • Constitutive expression and cytoplasmic compartmentalization of ATM protein in differentiated human neuron-like SH-SY5Y cells
    • Boehrs J.K., He J., Halaby M., Yang D. Constitutive expression and cytoplasmic compartmentalization of ATM protein in differentiated human neuron-like SH-SY5Y cells. J. Neurochem. 2007, 100:337-345.
    • (2007) J. Neurochem. , vol.100 , pp. 337-345
    • Boehrs, J.K.1    He, J.2    Halaby, M.3    Yang, D.4
  • 16
    • 35348979671 scopus 로고    scopus 로고
    • ATM, the Mre11/Rad50/Nbs1 complex, and topoisomerase I are concentrated in the nucleus of purkinje neurons in the juvenile human brain
    • Gorodetsky E., Calkins S., Ahn J., Brooks P.J. ATM, the Mre11/Rad50/Nbs1 complex, and topoisomerase I are concentrated in the nucleus of purkinje neurons in the juvenile human brain. DNA Repair 2007, 6:1698-1707.
    • (2007) DNA Repair , vol.6 , pp. 1698-1707
    • Gorodetsky, E.1    Calkins, S.2    Ahn, J.3    Brooks, P.J.4
  • 17
    • 72449147303 scopus 로고    scopus 로고
    • Cytoplasmic ATM in neurons modulates synaptic function
    • Li J., Han Y.R., Plummer M.R., Herrup K. Cytoplasmic ATM in neurons modulates synaptic function. Curr. Biol. 2009, 19:2091-2096.
    • (2009) Curr. Biol. , vol.19 , pp. 2091-2096
    • Li, J.1    Han, Y.R.2    Plummer, M.R.3    Herrup, K.4
  • 18
    • 84860692938 scopus 로고    scopus 로고
    • Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia
    • Li J., Chen J., Ricupero C.L., Hart R.P., Schwartz M.S., Kusnecov A., Herrup K. Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia. Nat. Med. 2012, 18:783-790.
    • (2012) Nat. Med. , vol.18 , pp. 783-790
    • Li, J.1    Chen, J.2    Ricupero, C.L.3    Hart, R.P.4    Schwartz, M.S.5    Kusnecov, A.6    Herrup, K.7
  • 19
    • 80053125089 scopus 로고    scopus 로고
    • The neuro-glial-vascular interrelations in genomic instability symptoms
    • Barzilai A. The neuro-glial-vascular interrelations in genomic instability symptoms. Mech. Ageing Dev. 2011, 132:395-404.
    • (2011) Mech. Ageing Dev. , vol.132 , pp. 395-404
    • Barzilai, A.1
  • 23
    • 34748919514 scopus 로고    scopus 로고
    • A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes
    • De Filippis L., Lamorte G., Snyder E.Y., Malgaroli A., Vescovi A.L. A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes. Stem Cells 2007, 25:2312-2321.
    • (2007) Stem Cells , vol.25 , pp. 2312-2321
    • Filippis, L.D.1    Lamorte, G.2    Snyder, E.Y.3    Malgaroli, A.4    Vescovi, A.L.5
  • 26
    • 67349278773 scopus 로고    scopus 로고
    • DNA-damage response, survival and differentiation in vitro of a human neural stem cell line in relation to ATM expression
    • Carlessi L., De Filippis L., Lecis D., Vescovi A., Delia D. DNA-damage response, survival and differentiation in vitro of a human neural stem cell line in relation to ATM expression. Cell Death Differ. 2009, 16:795-806.
    • (2009) Cell Death Differ. , vol.16 , pp. 795-806
    • Carlessi, L.1    De Filippis, L.2    Lecis, D.3    Vescovi, A.4    Delia, D.5
  • 28
    • 77956327999 scopus 로고    scopus 로고
    • Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants
    • Adams B.R., Golding S.E., Rao R.R., Valerie K. Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants. PLoS ONE 2010, 5:e10001.
    • (2010) PLoS ONE , vol.5
    • Adams, B.R.1    Golding, S.E.2    Rao, R.R.3    Valerie, K.4
  • 32
    • 77952722363 scopus 로고    scopus 로고
    • The checkpoint kinase ATM protects against stress-induced elevation of cyclin D1 and potential cell death in neurons
    • Hitomi M., Stacey D.W. The checkpoint kinase ATM protects against stress-induced elevation of cyclin D1 and potential cell death in neurons. Cytometry Part A 2010, 77A:524-533.
    • (2010) Cytometry Part A , vol.77 A , pp. 524-533
    • Hitomi, M.1    Stacey, D.W.2
  • 36
    • 58549092574 scopus 로고    scopus 로고
    • DNA repair deficiency and neurological disease
    • McKinnon.P.J. DNA repair deficiency and neurological disease. Nat. Rev. Neurosci. 2009, 10:100-112.
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 100-112
    • McKinnon, P.J.1
  • 37
    • 33745186920 scopus 로고    scopus 로고
    • Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells
    • Biton S., Dar I., Mittelman L., Pereg Y., Barzilai A., Shiloh Y. Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells. J. Biol. Chem. 2006, 281:17482-17491.
    • (2006) J. Biol. Chem. , vol.281 , pp. 17482-17491
    • Biton, S.1    Dar, I.2    Mittelman, L.3    Pereg, Y.4    Barzilai, A.5    Shiloh, Y.6
  • 38
    • 68549104117 scopus 로고    scopus 로고
    • The role of oxygen in regulating neural stem cells in development and disease
    • Panchision D.M. The role of oxygen in regulating neural stem cells in development and disease. J. Cell. Physiol. 2009, 220:562-568.
    • (2009) J. Cell. Physiol. , vol.220 , pp. 562-568
    • Panchision, D.M.1
  • 39
    • 80051786375 scopus 로고    scopus 로고
    • Hypoxia in the regulation of neural stem cells
    • De Filippis L., Delia D. Hypoxia in the regulation of neural stem cells. Cell. Mol. Life Sci. 2011, 68:2831-2844.
    • (2011) Cell. Mol. Life Sci. , vol.68 , pp. 2831-2844
    • De Filippis, L.1    Delia, D.2
  • 40
    • 77956186783 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes
    • Hamanaka R.B., Chandel N.S. Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes. Trends Biochem. Sci. 2010, 35:505-513.
    • (2010) Trends Biochem. Sci. , vol.35 , pp. 505-513
    • Hamanaka, R.B.1    Chandel, N.S.2
  • 41
    • 70549092785 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species regulate hypoxic signaling
    • Hamanaka R.B., Chandel N.S. Mitochondrial reactive oxygen species regulate hypoxic signaling. Curr. Opin. Cell Biol. 2009, 21:894-899.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 894-899
    • Hamanaka, R.B.1    Chandel, N.S.2
  • 42
    • 37349014081 scopus 로고    scopus 로고
    • Tel2 regulates the stability of PI3K-related protein kinases
    • Takai H., Wang R.C., Takai K.K., Yang H., de Lange T. Tel2 regulates the stability of PI3K-related protein kinases. Cell 2007, 131:1248-1259.
    • (2007) Cell , vol.131 , pp. 1248-1259
    • Takai, H.1    Wang, R.C.2    Takai, K.K.3    Yang, H.4    de Lange, T.5
  • 44
    • 34547942307 scopus 로고    scopus 로고
    • Characteristics of neural stem cells expanded in lowered oxygen and the potential role of hypoxia-inducible factor-1Alpha
    • Zhang C.P., Zhu L.L., Zhao T., Zhao H., Huang X., Ma X., Wang H., Fan M. Characteristics of neural stem cells expanded in lowered oxygen and the potential role of hypoxia-inducible factor-1Alpha. Neurosignals 2006, 15:259-265.
    • (2006) Neurosignals , vol.15 , pp. 259-265
    • Zhang, C.P.1    Zhu, L.L.2    Zhao, T.3    Zhao, H.4    Huang, X.5    Ma, X.6    Wang, H.7    Fan, M.8
  • 48
    • 34247135646 scopus 로고    scopus 로고
    • Adult-onset ataxia-telangiectasia. A clinical and therapeutic observation
    • Gazulla J., Benavente I., Sarasa Barrio M. Adult-onset ataxia-telangiectasia. A clinical and therapeutic observation. Neurologia 2006, 21:447-451.
    • (2006) Neurologia , vol.21 , pp. 447-451
    • Gazulla, J.1    Benavente, I.2    Sarasa Barrio, M.3
  • 50
    • 0742305862 scopus 로고    scopus 로고
    • Using human neural stem cells to model neurological disease
    • Jakel R.J., Schneider B.L., Svendsen C.N. Using human neural stem cells to model neurological disease. Nat. Rev. Genet. 2004, 5:136-144.
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 136-144
    • Jakel, R.J.1    Schneider, B.L.2    Svendsen, C.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.