L-type CaV1.2 deletion in the cochlea but not in the brainstem reduces noise vulnerability: Implication for CaV1.2 mediated control of cochlear BDNF expression

Frontiers in Molecular Neuroscience

Volumn , Issue JULY, 2013, Pages

  Zuccotti, Annalisa ^a,f   Lee, Sze Chim ^a   Campanelli, Dario ^a   Singer, Wibke ^a   Satheesh, Somisetty Venkata ^b   Patriarchi, Tommaso ^d   Geisler, Hyun Soon ^a   Köpschall, Iris ^a   Rohbock, Karin ^a   Nothwang, Hans Gerd ^b   Hu, Jing ^c   Hell, Johannes W ^d   Schimmang, Thomas ^e   Rüttiger, Lukas ^a   Knipper, Marlies ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF OLDENBURG   (Germany)

^c Centre for Integrative Neuroscience   (Germany)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF VALLADOLID   (Spain)

^f UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

ABR; BDNF; CaV1.2; Inner ear; L VGCCs; SOC

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM CHANNEL CAV1.2; CALCIUM CHANNEL L TYPE; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUDITORY STIMULATION; AUDITORY SYSTEM; AUDITORY THRESHOLD; BRAIN STEM; COCHLEA; COCHLEAR NERVE; CONTROLLED STUDY; CORRELATION ANALYSIS; DORSAL COCHLEAR NUCLEUS; EGR2 GENE; EVOKED BRAIN STEM AUDITORY RESPONSE; FEEDBACK SYSTEM; GENE; GENE DELETION; HEARING IMPAIRMENT; INFERIOR COLLICULUS; KNOCKOUT MOUSE; MOUSE; NOISE; NOISE VULNERABILITY; NONHUMAN; PAX2 GENE; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SPIRAL GANGLION;

EID: 84880620993     PISSN: 16625099     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnmol.2013.00020     Document Type: Article

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