Lack of brain-derived neurotrophic factor hampers inner hair cell synapse physiology, but protects against noise-induced hearing loss

Journal of Neuroscience

Volumn 32, Issue 25, 2012, Pages 8545-8553

  Zuccotti, Annalisa ^a,e   Kuhn, Stephanie ^b   Johnson, Stuart L ^b   Franz, Christoph ^a   Singer, Wibke ^a   Hecker, Dietmar ^c   Geisler, Hyun Soon ^a   Köpschall, Iris ^a   Rohbock, Karin ^a   Gutsche, Katja ^d   Dlugaiczyk, Julia ^c   Schick, Bernhard ^c   Marcotti, Walter ^b   Rüttiger, Lukas ^c   Schimmang, Thomas ^d   Knipper, Marlies ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c SAARLAND UNIVERSITY   (Germany)

^d Universidad de Valladolid and Consejo Superior de Investigaciones Científicas   (Spain)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; COCHLEA; COCHLEAR NERVE; CONTROLLED STUDY; DISTORTION PRODUCT OTOACOUSTIC EMISSION; ELECTROPHYSIOLOGY; EVOKED BRAIN STEM AUDITORY RESPONSE; EXOCYTOSIS; FEMALE; HAIR CELL; HEARING LOSS; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MALE; MEMBRANE CONDUCTANCE; MEMBRANE STEADY POTENTIAL; MOUSE; NOISE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RNA PROBE; SYNAPSE; WAVEFORM; WESTERN BLOTTING;

ANIMALS; BETA-GALACTOSIDASE; BLOTTING, NORTHERN; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL COUNT; COCHLEA; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; EXOCYTOSIS; HAIR CELLS, AUDITORY, INNER; HEARING LOSS, NOISE-INDUCED; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; NOISE; OTOACOUSTIC EMISSIONS, SPONTANEOUS; PAX2 TRANSCRIPTION FACTOR; SYNAPSES;

EID: 84862848814     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1247-12.2012     Document Type: Article

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