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Volumn 32, Issue 6, 2011, Pages 366-375

Structural and functional differences between L-type calcium channels: Crucial issues for future selective targeting

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALMODULIN; CAV1.2 CALCIUM CHANNEL; CAV1.3 CALCIUM CHANNEL; DILTIAZEM; NIFEDIPINE; NIMODIPINE; STROMAL INTERACTION MOLECULE 1; UNCLASSIFIED DRUG; VERAPAMIL; VOLTAGE GATED CALCIUM CHANNEL;

EID: 79957685488     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2011.02.012     Document Type: Review
Times cited : (66)

References (94)
  • 1
    • 29844439240 scopus 로고    scopus 로고
    • International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels
    • Catterall, W.A. et al. (2005) International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels. Pharmacol. Rev. 57, 411-425
    • (2005) Pharmacol. Rev. , vol.57 , pp. 411-425
    • Catterall, W.A.1
  • 2
    • 59449106920 scopus 로고    scopus 로고
    • Expression and 1,4-dihydropyridine-binding properties of brain L-type calcium channel isoforms
    • Sinnegger-Brauns, M.J. et al. (2009) Expression and 1,4-dihydropyridine- binding properties of brain L-type calcium channel isoforms. Mol. Pharmacol. 75, 407-414
    • (2009) Mol. Pharmacol. , vol.75 , pp. 407-414
    • Sinnegger-Brauns, M.J.1
  • 3
    • 77955564204 scopus 로고    scopus 로고
    • Channelopathies in Cav1.1 Cav1. 3, and Cav1. 4 voltage-gated L-type Ca2+ channels
    • Striessnig, J. et al. (2010) Channelopathies in Cav1.1 Cav1. 3, and Cav1. 4 voltage-gated L-type Ca2+ channels. Pflugers Arch. 460, 361-374
    • (2010) Pflugers Arch. , vol.460 , pp. 361-374
    • Striessnig, J.1
  • 4
    • 55749094173 scopus 로고    scopus 로고
    • Exploring the function and pharmacotherapeutic potential of voltage-gated Ca2+ channels with gene knockout models
    • Striessnig, J. and Koschak, A. (2008) Exploring the function and pharmacotherapeutic potential of voltage-gated Ca2+ channels with gene knockout models. Channels (Austin) 2, 233-251
    • (2008) Channels (Austin) , vol.2 , pp. 233-251
    • Striessnig, J.1    Koschak, A.2
  • 5
    • 77955589558 scopus 로고    scopus 로고
    • CaV1.2 channelopathies: From arrhythmias to autism, bipolar disorder, and immunodeficiency
    • Liao, P. and Soong, T.W. (2010) CaV1.2 channelopathies: from arrhythmias to autism, bipolar disorder, and immunodeficiency. Pflugers Arch. 460, 353-359
    • (2010) Pflugers Arch. , vol.460 , pp. 353-359
    • Liao, P.1    Soong, T.W.2
  • 6
    • 78650676678 scopus 로고    scopus 로고
    • Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness
    • Baig, S.M. et al. (2011) Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness. Nat. Neurosci. 14, 77-84
    • (2011) Nat. Neurosci. , vol.14 , pp. 77-84
    • Baig, S.M.1
  • 7
    • 34248995257 scopus 로고    scopus 로고
    • The action potential in mammalian central neurons
    • Bean, B.P. (2007) The action potential in mammalian central neurons. Nat. Rev. Neurosci. 8, 451-465
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 451-465
    • Bean, B.P.1
  • 8
    • 34347359673 scopus 로고    scopus 로고
    • 'Rejuvenation' protects neurons in mouse models of Parkinson's disease
    • Chan, C.S. et al. (2007) 'Rejuvenation' protects neurons in mouse models of Parkinson's disease. Nature 447, 1081-1086
    • (2007) Nature , vol.447 , pp. 1081-1086
    • Chan, C.S.1
  • 9
    • 33846453291 scopus 로고    scopus 로고
    • Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons
    • DOI 10.1523/JNEUROSCI.4341-06.2007
    • Puopolo, M. et al. (2007) Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons. J. Neurosci. 27, 645-656 (Pubitemid 46143768)
    • (2007) Journal of Neuroscience , vol.27 , Issue.3 , pp. 645-656
    • Puopolo, M.1    Raviola, E.2    Bean, B.P.3
  • 10
    • 50349096521 scopus 로고    scopus 로고
    • Genesis and regulation of the heart automaticity
    • Mangoni, M.E. and Nargeot, J. (2008) Genesis and regulation of the heart automaticity. Physiol. Rev. 88, 919-982
    • (2008) Physiol. Rev. , vol.88 , pp. 919-982
    • Mangoni, M.E.1    Nargeot, J.2
  • 11
    • 74949101892 scopus 로고    scopus 로고
    • Loss of Cav1.3 channels reveals the critical role of L-type and BK channel coupling in pacemaking mouse adrenal chromaffin cells
    • Marcantoni, A. et al. (2010) Loss of Cav1.3 channels reveals the critical role of L-type and BK channel coupling in pacemaking mouse adrenal chromaffin cells. J. Neurosci. 30, 491-504
    • (2010) J. Neurosci. , vol.30 , pp. 491-504
    • Marcantoni, A.1
  • 12
    • 0242475156 scopus 로고    scopus 로고
    • Sodium and calcium currents shape action potentials in immature mouse inner hair cells
    • DOI 10.1113/jphysiol.2003.043612
    • Marcotti, W. et al. (2003) Sodium and calcium currents shape action potentials in immature mouse inner hair cells. J. Physiol. 552, 743-761 (Pubitemid 37428417)
    • (2003) Journal of Physiology , vol.552 , Issue.3 , pp. 743-761
    • Marcotti, W.1    Johnson, S.L.2    Rusch, A.3    Kros, C.J.4
  • 13
    • 51049090202 scopus 로고    scopus 로고
    • Modulation of voltage- and Ca2+-dependent gating of CaV1.3 L-type calcium channels by alternative splicing of a C-terminal regulatory domain
    • Singh, A. et al. (2008) Modulation of voltage- and Ca2+-dependent gating of CaV1.3 L-type calcium channels by alternative splicing of a C-terminal regulatory domain. J. Biol. Chem. 283, 20733-20744
    • (2008) J. Biol. Chem. , vol.283 , pp. 20733-20744
    • Singh, A.1
  • 14
    • 78650966433 scopus 로고    scopus 로고
    • Ca(v)1.3 and BK channels for timing and regulating cell firing
    • Vandael, D.H. et al. (2010) Ca(v)1.3 and BK channels for timing and regulating cell firing. Mol. Neurobiol. 42, 185-198
    • (2010) Mol. Neurobiol. , vol.42 , pp. 185-198
    • Vandael, D.H.1
  • 15
    • 0031434002 scopus 로고    scopus 로고
    • Hair cell-specific splicing of mRNA for the alpha1D subunit of voltage-gated Ca2+ channels in the chicken's cochlea
    • Kollmar, R. et al. (1997) Hair cell-specific splicing of mRNA for the alpha1D subunit of voltage-gated Ca2+ channels in the chicken's cochlea. Proc. Natl. Acad. Sci. U.S.A. 94, 14889-14893
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 14889-14893
    • Kollmar, R.1
  • 16
    • 9644264030 scopus 로고    scopus 로고
    • Smooth muscle-selective alternatively spliced exon generates functional variation in Cav1.2 calcium channels
    • Liao, P. et al. (2004) Smooth muscle-selective alternatively spliced exon generates functional variation in Cav1.2 calcium channels. J. Biol. Chem. 279, 50329-50335
    • (2004) J. Biol. Chem. , vol.279 , pp. 50329-50335
    • Liao, P.1
  • 17
    • 68649099001 scopus 로고    scopus 로고
    • Calcium channel diversity: Multiple roles of calcium channel subunits
    • Dolphin, A.C. (2009) Calcium channel diversity: multiple roles of calcium channel subunits. Curr. Opin. Neurobiol. 19, 237-244
    • (2009) Curr. Opin. Neurobiol. , vol.19 , pp. 237-244
    • Dolphin, A.C.1
  • 18
    • 67649739370 scopus 로고    scopus 로고
    • Pore stability and gating in voltage-activated calcium channels
    • Hering, S. et al. (2008) Pore stability and gating in voltage-activated calcium channels. Channels (Austin) 2, 61-69
    • (2008) Channels (Austin) , vol.2 , pp. 61-69
    • Hering, S.1
  • 19
    • 66449097492 scopus 로고    scopus 로고
    • Coupled and independent contributions of residues in IS6 and IIS6 to activation gating of CaV1.2
    • Kudrnac, M. et al. (2009) Coupled and independent contributions of residues in IS6 and IIS6 to activation gating of CaV1.2. J. Biol. Chem. 284, 12276-12284
    • (2009) J. Biol. Chem. , vol.284 , pp. 12276-12284
    • Kudrnac, M.1
  • 20
    • 78751643127 scopus 로고    scopus 로고
    • Physicochemical properties of pore residues predict activation gating of Ca(V)1.2: A correlation mutation analysis
    • Beyl, S. et al. (2011) Physicochemical properties of pore residues predict activation gating of Ca(V)1.2: a correlation mutation analysis. Pflugers Arch. 461, 53-63
    • (2011) Pflugers Arch. , vol.461 , pp. 53-63
    • Beyl, S.1
  • 21
    • 1542298943 scopus 로고    scopus 로고
    • 2+ channels
    • DOI 10.1016/S0896-6273(04)00081-9, PII S0896627304000819
    • Kim, J. et al. (2004) Identification of the components controlling inactivation of voltage-gated Ca2+ channels. Neuron 41, 745-754 (Pubitemid 38326837)
    • (2004) Neuron , vol.41 , Issue.5 , pp. 745-754
    • Kim, J.1    Ghosh, S.2    Nunziato, D.A.3    Pitt, G.S.4
  • 22
    • 77649143136 scopus 로고    scopus 로고
    • Molecular endpoints of Ca2+/calmodulin-and voltage-dependent inactivation of Ca(v)1.3 channels
    • Tadross, M.R. et al. (2010) Molecular endpoints of Ca2+/calmodulin-and voltage-dependent inactivation of Ca(v)1.3 channels. J. Gen. Physiol. 135, 197-215
    • (2010) J. Gen. Physiol. , vol.135 , pp. 197-215
    • Tadross, M.R.1
  • 23
    • 33644684859 scopus 로고    scopus 로고
    • Structural determinants of L-type channel activation in segment IIS6 revealed by a retinal disorder
    • Hohaus, A. et al. (2005) Structural determinants of L-type channel activation in segment IIS6 revealed by a retinal disorder. J. Biol. Chem. 280, 38471-38477
    • (2005) J. Biol. Chem. , vol.280 , pp. 38471-38477
    • Hohaus, A.1
  • 24
    • 33646149627 scopus 로고    scopus 로고
    • A novel molecular inactivation determinant of voltage-gated CaV1.2 L-type Ca2+ channel
    • Livneh, A. et al. (2006) A novel molecular inactivation determinant of voltage-gated CaV1.2 L-type Ca2+ channel. Neuroscience 139, 1275-1287
    • (2006) Neuroscience , vol.139 , pp. 1275-1287
    • Livneh, A.1
  • 25
    • 0027236205 scopus 로고
    • 2+ conductances in guinea-pig substantia nigra pars compacta neurones
    • Nedergaard, S. et al. (1993) Nifedipine- and omega-conotoxin-sensitive Ca2+ conductances in guinea-pig substantia nigra pars compacta neurones. J. Physiol. 466, 727-747 (Pubitemid 23225251)
    • (1993) Journal of Physiology , vol.466 , pp. 727-747
    • Nedergaard, S.1    Flatman, J.A.2    Engberg, I.3
  • 26
    • 0027943813 scopus 로고
    • Effects of dihydropyridine calcium antagonists on rat midbrain dopaminergic neurones
    • Mercuri, N.B. et al. (1994) Effects of dihydropyridine calcium antagonists on rat midbrain dopaminergic neurones. Br. J. Pharmacol. 113, 831-838
    • (1994) Br. J. Pharmacol. , vol.113 , pp. 831-838
    • Mercuri, N.B.1
  • 27
    • 0035114299 scopus 로고    scopus 로고
    • Immunohistochemical localization of voltage-gated calcium channels in substantia nigra dopamine neurons
    • Takada, M. et al. (2001) Immunohistochemical localization of voltage-gated calcium channels in substantia nigra dopamine neurons. Eur. J. Neurosci. 13, 757-762
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 757-762
    • Takada, M.1
  • 28
    • 77954323103 scopus 로고    scopus 로고
    • Alternative splicing modulates diltiazem sensitivity of cardiac and vascular smooth muscle Ca(v)1.2 calcium channels
    • Zhang, H.Y. et al. (2010) Alternative splicing modulates diltiazem sensitivity of cardiac and vascular smooth muscle Ca(v)1.2 calcium channels. Br. J. Pharmacol. 160, 1631-1640
    • (2010) Br. J. Pharmacol. , vol.160 , pp. 1631-1640
    • Zhang, H.Y.1
  • 29
    • 0034794289 scopus 로고    scopus 로고
    • Requirement for the L-type Ca(2+) channel alpha(1D) subunit in postnatal pancreatic beta cell generation
    • Namkung, Y. et al. (2001) Requirement for the L-type Ca(2+) channel alpha(1D) subunit in postnatal pancreatic beta cell generation. J. Clin. Invest. 108, 1015-1022
    • (2001) J. Clin. Invest. , vol.108 , pp. 1015-1022
    • Namkung, Y.1
  • 30
    • 25644448104 scopus 로고    scopus 로고
    • Maintenance of stimulus-secretion coupling and single beta-cell function in cryopreserved-thawed human islets of Langerhans
    • DOI 10.1007/s00424-005-1401-y
    • Misler, S. et al. (2005) Maintenance of stimulus-secretion coupling and single beta-cell function in cryopreserved-thawed human islets of Langerhans. Pflugers Arch. 450, 395-404 (Pubitemid 41380698)
    • (2005) Pflugers Archiv European Journal of Physiology , vol.450 , Issue.6 , pp. 395-404
    • Misler, S.1    Dickey, A.2    Barnett, D.W.3
  • 31
    • 77953920801 scopus 로고    scopus 로고
    • Calcium signaling in the islets
    • Islam, M.S. (2010) Calcium signaling in the islets. Adv. Exp. Med. Biol. 654, 235-259
    • (2010) Adv. Exp. Med. Biol. , vol.654 , pp. 235-259
    • Islam, M.S.1
  • 32
    • 48249083049 scopus 로고    scopus 로고
    • Voltage-gated ion channels in human pancreatic beta-cells: Electrophysiological characterization and role in insulin secretion
    • Braun, M. et al. (2008) Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterization and role in insulin secretion. Diabetes 57, 1618-1628
    • (2008) Diabetes , vol.57 , pp. 1618-1628
    • Braun, M.1
  • 33
    • 77953945190 scopus 로고    scopus 로고
    • Electrophysiology of islet cells
    • Drews, G. et al. (2010) Electrophysiology of islet cells. Adv. Exp. Med. Biol. 654, 115-163
    • (2010) Adv. Exp. Med. Biol. , vol.654 , pp. 115-163
    • Drews, G.1
  • 34
    • 33645808245 scopus 로고    scopus 로고
    • Characterization of voltage-dependent sodium and calcium channels in mouse pancreatic A- and B-cells
    • Vignali, S. et al. (2006) Characterization of voltage-dependent sodium and calcium channels in mouse pancreatic A- and B-cells. J. Physiol. 572, 691-706
    • (2006) J. Physiol. , vol.572 , pp. 691-706
    • Vignali, S.1
  • 35
  • 36
    • 0029088566 scopus 로고
    • CACN4, the major alpha 1 subunit isoform of voltage-dependent calcium channels in pancreatic beta-cells: A minireview of current progress
    • Seino, S. (1995) CACN4, the major alpha 1 subunit isoform of voltage-dependent calcium channels in pancreatic beta-cells: a minireview of current progress. Diabetes Res. Clin. Pract. 28 (Suppl.), S99-103
    • (1995) Diabetes Res. Clin. Pract. , vol.28 , Issue.SUPPL.
    • Seino, S.1
  • 37
    • 71949109145 scopus 로고    scopus 로고
    • The making of synaptic ribbons: How they are built and what they do
    • Schmitz, F. (2009) The making of synaptic ribbons: how they are built and what they do. Neuroscientist 15, 611-624
    • (2009) Neuroscientist , vol.15 , pp. 611-624
    • Schmitz, F.1
  • 38
    • 34247867883 scopus 로고    scopus 로고
    • L-type calcium channels are preferentially coupled to endocytosis in bovine chromaffin cells
    • Rosa, J.M. et al. (2007) L-type calcium channels are preferentially coupled to endocytosis in bovine chromaffin cells. Biochem. Biophys. Res. Commun. 357, 834-839
    • (2007) Biochem. Biophys. Res. Commun. , vol.357 , pp. 834-839
    • Rosa, J.M.1
  • 39
    • 18744384968 scopus 로고    scopus 로고
    • Fast vesicle replenishment allows indefatigable signalling at the first auditory synapse
    • DOI 10.1038/nature03567
    • Griesinger, C.B. et al. (2005) Fast vesicle replenishment allows indefatigable signalling at the first auditory synapse. Nature 435, 212-215 (Pubitemid 40685947)
    • (2005) Nature , vol.435 , Issue.7039 , pp. 212-215
    • Griesinger, C.B.1    Richards, C.D.2    Ashmore, J.F.3
  • 40
    • 78650830600 scopus 로고    scopus 로고
    • Ca(V)1. 3 as pacemaker channels in adrenal chromaffin cells: Specific role on exo- And endocytosis?
    • Comunanza, V. et al. (2010) Ca(V)1. 3 as pacemaker channels in adrenal chromaffin cells: specific role on exo- and endocytosis? Channels (Austin) 4, 440-446
    • (2010) Channels (Austin) , vol.4 , pp. 440-446
    • Comunanza, V.1
  • 41
    • 77952029221 scopus 로고    scopus 로고
    • Deciphering the splicing code
    • Barash, Y. et al. (2010) Deciphering the splicing code. Nature 465, 53-59
    • (2010) Nature , vol.465 , pp. 53-59
    • Barash, Y.1
  • 42
    • 42449087363 scopus 로고    scopus 로고
    • Ca(v)1 L-type Ca2+ channel signaling complexes in neurons
    • Calin-Jageman, I. and Lee, A. (2008) Ca(v)1 L-type Ca2+ channel signaling complexes in neurons. J. Neurochem. 105, 573-583
    • (2008) J. Neurochem. , vol.105 , pp. 573-583
    • Calin-Jageman, I.1    Lee, A.2
  • 43
    • 38149103473 scopus 로고    scopus 로고
    • Ultrastructural evidence for pre- And postsynaptic localization of Cav1.2 L-type Ca2+ channels in the rat hippocampus
    • Tippens, A.L. et al. (2008) Ultrastructural evidence for pre- and postsynaptic localization of Cav1.2 L-type Ca2+ channels in the rat hippocampus. J. Comp. Neurol. 506, 569-583
    • (2008) J. Comp. Neurol. , vol.506 , pp. 569-583
    • Tippens, A.L.1
  • 44
    • 54449092370 scopus 로고    scopus 로고
    • cAMP/PKA signaling and RIM1alpha mediate presynaptic LTP in the lateral amygdala
    • Fourcaudot, E. et al. (2008) cAMP/PKA signaling and RIM1alpha mediate presynaptic LTP in the lateral amygdala. Proc. Natl. Acad. Sci. U.S.A. 105, 15130-15135
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 15130-15135
    • Fourcaudot, E.1
  • 46
    • 55849130994 scopus 로고    scopus 로고
    • Communication between the synapse and the nucleus in neuronal development, plasticity, and disease
    • Cohen, S. and Greenberg, M.E. (2008) Communication between the synapse and the nucleus in neuronal development, plasticity, and disease. Annu. Rev. Cell Dev. Biol. 24, 183-209
    • (2008) Annu. Rev. Cell Dev. Biol. , vol.24 , pp. 183-209
    • Cohen, S.1    Greenberg, M.E.2
  • 47
    • 33646446634 scopus 로고    scopus 로고
    • Regulation of voltage-gated Ca2+ channels by calmodulin
    • Halling, D.B. et al. (2006) Regulation of voltage-gated Ca2+ channels by calmodulin. Sci. STKE 2006, er1
    • (2006) Sci. STKE , vol.2006
    • Halling, D.B.1
  • 49
    • 77953439656 scopus 로고    scopus 로고
    • Facilitation of murine cardiac L-type Ca(v)1.2 channel is modulated by calmodulin kinase II-dependent phosphorylation of S1512 and S1570
    • Blaich, A. et al. (2010) Facilitation of murine cardiac L-type Ca(v)1.2 channel is modulated by calmodulin kinase II-dependent phosphorylation of S1512 and S1570. Proc. Natl. Acad. Sci. U.S.A. 107, 10285-10289
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 10285-10289
    • Blaich, A.1
  • 50
    • 77950974013 scopus 로고    scopus 로고
    • Ca2+-dependent facilitation of Cav1.3 Ca2+ channels by densin and Ca2+/calmodulin-dependent protein kinase II
    • Jenkins, M.A. et al. (2010) Ca2+-dependent facilitation of Cav1.3 Ca2+ channels by densin and Ca2+/calmodulin-dependent protein kinase II. J. Neurosci. 30, 5125-5135
    • (2010) J. Neurosci. , vol.30 , pp. 5125-5135
    • Jenkins, M.A.1
  • 51
    • 33745614665 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 modulation of CaV1.3 calcium channels depends on Ca2+ release from IP3-sensitive stores and calcium/calmodulin kinase II phosphorylation of the alpha1 subunit EF hand
    • Gao, L. et al. (2006) Insulin-like growth factor-1 modulation of CaV1.3 calcium channels depends on Ca2+ release from IP3-sensitive stores and calcium/calmodulin kinase II phosphorylation of the alpha1 subunit EF hand. J. Neurosci. 26, 6259-6268
    • (2006) J. Neurosci. , vol.26 , pp. 6259-6268
    • Gao, L.1
  • 53
    • 33646698386 scopus 로고    scopus 로고
    • Ca1.2 and CaV1.3 neuronal L-type calcium channels: Differential targeting and signaling to pCREB
    • Zhang, H. et al. (2006) Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB. Eur. J. Neurosci. 23, 2297-2310
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 2297-2310
    • Zhang, H.1
  • 54
    • 77953024862 scopus 로고    scopus 로고
    • Physiologic gating properties of unitary cardiac L-type Ca2+ channels
    • Josephson, I.R. et al. (2010) Physiologic gating properties of unitary cardiac L-type Ca2+ channels. Biochem. Biophys. Res. Commun. 396, 763-766
    • (2010) Biochem. Biophys. Res. Commun. , vol.396 , pp. 763-766
    • Josephson, I.R.1
  • 55
    • 34848851969 scopus 로고    scopus 로고
    • Postsynaptic secretion of BDNF and NT-3 from hippocampal neurons depends on calcium-calmodulin kinase II signaling and proceeds via delayed fusion pore opening
    • DOI 10.1523/JNEUROSCI.0692-07.2007
    • Kolarow, R. et al. (2007) Postsynaptic secretion of BDNF and NT-3 from hippocampal neurons depends on calcium calmodulin kinase II signaling and proceeds via delayed fusion pore opening. J. Neurosci. 27, 10350-10364 (Pubitemid 47501996)
    • (2007) Journal of Neuroscience , vol.27 , Issue.39 , pp. 10350-10364
    • Kolarow, R.1    Brigadski, T.2    Lessmann, V.3
  • 56
    • 36349037017 scopus 로고    scopus 로고
    • Functional interaction of neuronal Cav1.3 L-type calcium channel with ryanodine receptor type 2 in the rat hippocampus
    • Kim, S. et al. (2007) Functional interaction of neuronal Cav1.3 L-type calcium channel with ryanodine receptor type 2 in the rat hippocampus. J. Biol. Chem. 282, 32877-32889
    • (2007) J. Biol. Chem. , vol.282 , pp. 32877-32889
    • Kim, S.1
  • 58
    • 0036310678 scopus 로고    scopus 로고
    • A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells
    • Barg, S. et al. (2002) A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells. Diabetes 51 (Suppl. 1), S74-82
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 1
    • Barg, S.1
  • 59
    • 33751032385 scopus 로고    scopus 로고
    • Calcium microdomains: Organization and function
    • Berridge, M.J. (2006) Calcium microdomains: organization and function. Cell Calcium 40, 405-412
    • (2006) Cell Calcium , vol.40 , pp. 405-412
    • Berridge, M.J.1
  • 60
    • 77953282058 scopus 로고    scopus 로고
    • Induction of fear extinction with hippocampalinfralimbic BDNF
    • Peters, J. et al. (2010) Induction of fear extinction with hippocampalinfralimbic BDNF. Science 328, 1288-1290
    • (2010) Science , vol.328 , pp. 1288-1290
    • Peters, J.1
  • 62
    • 77954117096 scopus 로고    scopus 로고
    • Homeostatic switch in hebbian plasticity and fear learning after sustained loss of Cav1.2 calcium channels
    • Langwieser, N. et al. (2010) Homeostatic switch in hebbian plasticity and fear learning after sustained loss of Cav1.2 calcium channels. J. Neurosci. 30, 8367-8375
    • (2010) J. Neurosci. , vol.30 , pp. 8367-8375
    • Langwieser, N.1
  • 63
    • 8544271710 scopus 로고    scopus 로고
    • Ca(2+)-induced Ca(2+) release via inositol 1,4,5-trisphosphate receptors is amplified by protein kinase A and triggers exocytosis in pancreatic beta-cells
    • Dyachok, O. and Gylfe, E. (2004) Ca(2+)-induced Ca(2+) release via inositol 1,4,5-trisphosphate receptors is amplified by protein kinase A and triggers exocytosis in pancreatic beta-cells. J. Biol. Chem. 279, 45455-45461
    • (2004) J. Biol. Chem. , vol.279 , pp. 45455-45461
    • Dyachok, O.1    Gylfe, E.2
  • 64
    • 64749108983 scopus 로고    scopus 로고
    • The role of mammalian cardiac t-tubules in excitation-contraction coupling: Experimental and computational approaches
    • Orchard, C.H. et al. (2009) The role of mammalian cardiac t-tubules in excitation-contraction coupling: experimental and computational approaches. Exp. Physiol. 94, 509-519
    • (2009) Exp. Physiol. , vol.94 , pp. 509-519
    • Orchard, C.H.1
  • 65
    • 34447512735 scopus 로고    scopus 로고
    • Ca2+ entry-independent effects of L-type Ca2+ channel modulators on Ca2+ sparks in ventricular myocytes
    • Copello, J.A. et al. (2007) Ca2+ entry-independent effects of L-type Ca2+ channel modulators on Ca2+ sparks in ventricular myocytes. Am. J. Physiol. Cell Physiol. 292, C2129-2140
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292
    • Copello, J.A.1
  • 67
    • 0035846944 scopus 로고    scopus 로고
    • Alternative splicing in intracellular loop connecting domains II and III of the alpha 1 subunit of Cav1.2 Ca2+ channels predicts two-domain polypeptides with unique Cterminal tails
    • Wielowieyski, P.A. et al. (2001) Alternative splicing in intracellular loop connecting domains II and III of the alpha 1 subunit of Cav1.2 Ca2+ channels predicts two-domain polypeptides with unique Cterminal tails. J. Biol. Chem. 276, 1398-1406
    • (2001) J. Biol. Chem. , vol.276 , pp. 1398-1406
    • Wielowieyski, P.A.1
  • 68
    • 77957349183 scopus 로고    scopus 로고
    • The calcium store sensor STIM1, reciprocally controls Orai and CaV1. 2 channels
    • Wang, Y. et al. (2010) The calcium store sensor STIM1, reciprocally controls Orai and CaV1. 2 channels. Science 330, 105-109
    • (2010) Science , vol.330 , pp. 105-109
    • Wang, Y.1
  • 69
    • 77957332175 scopus 로고    scopus 로고
    • The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels
    • Park, C.Y. et al. (2010) The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. Science 330, 101-105
    • (2010) Science , vol.330 , pp. 101-105
    • Park, C.Y.1
  • 70
    • 67649121812 scopus 로고    scopus 로고
    • Homeostatic and stimulus-induced coupling of the L-type Ca2+ channel to the ryanodine receptor in the hippocampal neuron in slices
    • Berrout, J. and Isokawa, M. (2009) Homeostatic and stimulus-induced coupling of the L-type Ca2+ channel to the ryanodine receptor in the hippocampal neuron in slices. Cell Calcium 46, 30-38
    • (2009) Cell Calcium , vol.46 , pp. 30-38
    • Berrout, J.1    Isokawa, M.2
  • 71
    • 77956040602 scopus 로고    scopus 로고
    • High-quality binary interactome mapping
    • Dreze, M. et al. (2010) High-quality binary interactome mapping. Methods Enzymol. 470, 281-315
    • (2010) Methods Enzymol. , vol.470 , pp. 281-315
    • Dreze, M.1
  • 72
    • 52049125960 scopus 로고    scopus 로고
    • Control of K(Ca) channels by calcium nano/microdomains
    • Fakler, B. and Adelman, J.P. (2008) Control of K(Ca) channels by calcium nano/microdomains. Neuron 59, 873-881
    • (2008) Neuron , vol.59 , pp. 873-881
    • Fakler, B.1    Adelman, J.P.2
  • 73
    • 33846045555 scopus 로고    scopus 로고
    • Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2
    • Lu, L. et al. (2007) Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2. Circ. Res. 100, 112-120
    • (2007) Circ. Res. , vol.100 , pp. 112-120
    • Lu, L.1
  • 74
    • 0345491881 scopus 로고    scopus 로고
    • v1.3 Channels Are Essential for Development and Presynaptic Activity of Cochlear Inner Hair Cells
    • Brandt, A. et al. (2003) CaV1.3 channels are essential for development and presynaptic activity of cochlear inner hair cells. J. Neurosci. 23, 10832-10840 (Pubitemid 37499690)
    • (2003) Journal of Neuroscience , vol.23 , Issue.34 , pp. 10832-10840
    • Brandt, A.1    Striessnig, J.2    Moser, T.3
  • 75
    • 70349855214 scopus 로고    scopus 로고
    • Daily electrical silencing in the mammalian circadian clock
    • Belle, M.D. et al. (2009) Daily electrical silencing in the mammalian circadian clock. Science 326, 281-284
    • (2009) Science , vol.326 , pp. 281-284
    • Belle, M.D.1
  • 76
    • 0027059034 scopus 로고
    • Mapping of a human brain voltage-gated calcium channel to human chromosome 12p13-pter
    • DOI 10.1016/S0888-7543(05)80135-1
    • Sun, W. et al. (1992) Mapping of a human brain voltage-gated calcium channel to human chromosome 12p13-pter. Genomics 14, 1092-1094 (Pubitemid 23053051)
    • (1992) Genomics , vol.14 , Issue.4 , pp. 1092-1094
    • Sun, W.1    McPherson, J.D.2    Hoang, D.Q.3    Wasmuth, J.J.4    Evans, G.A.5    Montal, M.6
  • 77
    • 0026706497 scopus 로고
    • Assignment of the gene encoding the alpha 1 subunit of the neuroendocrine/brain-type calcium channel (CACNL1A2) to human chromosome 3, band p14.3
    • Seino, S. et al. (1992) Assignment of the gene encoding the alpha 1 subunit of the neuroendocrine/brain-type calcium channel (CACNL1A2) to human chromosome 3, band p14.3. Genomics 13, 1375-1377
    • (1992) Genomics , vol.13 , pp. 1375-1377
    • Seino, S.1
  • 79
    • 20444426877 scopus 로고    scopus 로고
    • Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations
    • discussion 8086-8088
    • Splawski, I. et al. (2005) Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations. Proc. Natl. Acad. Sci. U.S.A. 102, 8089-8096 discussion 8086-8088
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 8089-8096
    • Splawski, I.1
  • 80
    • 77449148751 scopus 로고    scopus 로고
    • CACNA1C gene polymorphisms, cardiovascular disease outcomes, and treatment response
    • Beitelshees, A.L. et al. (2009) CACNA1C gene polymorphisms, cardiovascular disease outcomes, and treatment response. Circ. Cardiovasc. Genet. 2, 362-370
    • (2009) Circ. Cardiovasc. Genet. , vol.2 , pp. 362-370
    • Beitelshees, A.L.1
  • 81
    • 0345492460 scopus 로고    scopus 로고
    • A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International Verapamil-Trandolapril Study (INVEST): A randomized controlled trial
    • Pepine, C.J. et al. (2003) A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International Verapamil-Trandolapril Study (INVEST): a randomized controlled trial. JAMA 290, 2805-2816
    • (2003) JAMA , vol.290 , pp. 2805-2816
    • Pepine, C.J.1
  • 82
    • 68849093429 scopus 로고    scopus 로고
    • Effects of CYP3A5, MDR1 and CACNA1C polymorphisms on the oral disposition and response of nimodipine in a Chinese cohort
    • Zhao, Y. et al. (2009) Effects of CYP3A5, MDR1 and CACNA1C polymorphisms on the oral disposition and response of nimodipine in a Chinese cohort. Eur. J. Clin. Pharmacol. 65, 579-584
    • (2009) Eur. J. Clin. Pharmacol. , vol.65 , pp. 579-584
    • Zhao, Y.1
  • 83
    • 33646021938 scopus 로고    scopus 로고
    • CACNA1C polymorphisms are associated with the efficacy of calcium channel blockers in the treatment of hypertension
    • Bremer, T. et al. (2006) CACNA1C polymorphisms are associated with the efficacy of calcium channel blockers in the treatment of hypertension. Pharmacogenomics 7, 271-279
    • (2006) Pharmacogenomics , vol.7 , pp. 271-279
    • Bremer, T.1
  • 84
    • 65649121868 scopus 로고    scopus 로고
    • Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers
    • Kamide, K. et al. (2009) Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers. Circ. J. 73, 732-740
    • (2009) Circ. J. , vol.73 , pp. 732-740
    • Kamide, K.1
  • 85
    • 77954510735 scopus 로고    scopus 로고
    • The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia
    • Green, E.K. et al. (2010) The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Mol. Psychiatry 15, 1016-1022
    • (2010) Mol. Psychiatry , vol.15 , pp. 1016-1022
    • Green, E.K.1
  • 86
    • 78851470987 scopus 로고    scopus 로고
    • L-type calcium channels, psychiatric disorders: A brief review
    • Casamassima, F. et al. (2010) L-type calcium channels, psychiatric disorders: A brief review. Am. J. Med. Genet. B: Neuropsychiatr. Genet. 153B, 1373-1390
    • (2010) Am. J. Med. Genet. B: Neuropsychiatr. Genet. , vol.153 B , pp. 1373-1390
    • Casamassima, F.1
  • 87
    • 77955550908 scopus 로고    scopus 로고
    • Variations in FKBP5 and BDNF genes are suggestively associated with depression in a Swedish population-based cohort
    • Lavebratt, C. et al. (2010) Variations in FKBP5 and BDNF genes are suggestively associated with depression in a Swedish population-based cohort. J. Affect. Disord. 125, 249-255
    • (2010) J. Affect. Disord. , vol.125 , pp. 249-255
    • Lavebratt, C.1
  • 88
    • 84934438895 scopus 로고    scopus 로고
    • Systems biology approaches and tools for analysis of interactomes and multi-target drugs
    • Schrattenholz, A. et al. (2010) Systems biology approaches and tools for analysis of interactomes and multi-target drugs. Methods Mol. Biol. 662, 29-58
    • (2010) Methods Mol. Biol. , vol.662 , pp. 29-58
    • Schrattenholz, A.1
  • 89
    • 78449290661 scopus 로고    scopus 로고
    • The spliceosomal proteome: At the heart of the largest cellular ribonucleoprotein machine
    • Valadkhan, S. and Jaladat, Y. (2010) The spliceosomal proteome: at the heart of the largest cellular ribonucleoprotein machine. Proteomics 10, 4128-4141
    • (2010) Proteomics , vol.10 , pp. 4128-4141
    • Valadkhan, S.1    Jaladat, Y.2
  • 90
    • 77958549006 scopus 로고    scopus 로고
    • Large-scale protein interactome mapping: Strategies and opportunities
    • Lievens, S. et al. (2010) Large-scale protein interactome mapping: strategies and opportunities. Expert Rev. Proteomics 7, 679-690
    • (2010) Expert Rev. Proteomics , vol.7 , pp. 679-690
    • Lievens, S.1
  • 91
    • 0031719884 scopus 로고    scopus 로고
    • Molecular basis of drug interaction with L-type Ca2+ channels
    • Mitterdorfer, J. et al. (1998) Molecular basis of drug interaction with L-type Ca2+ channels. J. Bioenerg. Biomembr. 30, 319-334
    • (1998) J. Bioenerg. Biomembr. , vol.30 , pp. 319-334
    • Mitterdorfer, J.1
  • 92
    • 22644444450 scopus 로고    scopus 로고
    • Voltage-dependent calcium channels
    • Lacinova, L. (2005) Voltage-dependent calcium channels. Gen. Physiol. Biophys. 24 (Suppl. 1), 1-78
    • (2005) Gen. Physiol. Biophys. , vol.24 , Issue.SUPPL. 1 , pp. 1-78
    • Lacinova, L.1
  • 93
    • 11244328061 scopus 로고    scopus 로고
    • FPL 64176 modification of Ca(V)1.2 L-type calcium channels: Dissociation of effects on ionic current and gating current
    • McDonough, S.I. et al. (2005) FPL 64176 modification of Ca(V)1.2 L-type calcium channels: dissociation of effects on ionic current and gating current. Biophys. J. 88, 211-223
    • (2005) Biophys. J. , vol.88 , pp. 211-223
    • McDonough, S.I.1
  • 94
    • 26444466613 scopus 로고    scopus 로고
    • Splicing for alternative structures of Cav1.2 Ca2+ channels in cardiac and smooth muscles
    • Liao, P. et al. (2005) Splicing for alternative structures of Cav1.2 Ca2+ channels in cardiac and smooth muscles. Cardiovasc. Res. 68, 197-203
    • (2005) Cardiovasc. Res. , vol.68 , pp. 197-203
    • Liao, P.1


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