Upregulation of β-1,4-Galactosyltransferase i in Rat Spinal Cord with Experimental Autoimmune Encephalomyelitis

Journal of Molecular Neuroscience

Volumn 49, Issue 3, 2013, Pages 437-445

  Zhao, Jianmei ^a,b   Gao, Ying ^b   Cheng, Chun ^b   Yan, Meijuan ^b   Wang, Jian ^a  

^a CHILDREN S HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b NANTONG UNIVERSITY   (China)

Author keywords

1,4 galactosyltransferase I; Experimental autoimmune encephalomyelitis; Multiple sclerosis; Rat; Spinal cord

Indexed keywords

BETA 1,4 GALACTOSYLTRANSFERASE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FREUND ADJUVANT; GLYCOSYLTRANSFERASE; UNCLASSIFIED DRUG; BETA 1,4 GALACTOSYLTRANSFERASE I; BETA-1,4-GALACTOSYLTRANSFERASE I; GALACTOSE; GALACTOSYLTRANSFERASE; GLYCOPROTEIN; MYELIN BASIC PROTEIN; NERVE PROTEIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GUINEA PIG; IMMUNOHISTOCHEMISTRY; MOLECULAR WEIGHT; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; RAT; SPINAL CORD; UPREGULATION; WESTERN BLOTTING; WHITE MATTER; ANIMAL; BIOSYNTHESIS; ENZYME INDUCTION; ENZYMOLOGY; GENETICS; GLYCOSYLATION; IMMUNOLOGY; LEWIS RAT; MACROPHAGE; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROTEIN PROCESSING;

RATTUS; RICINUS COMMUNIS;

ANIMALS; E-SELECTIN; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME INDUCTION; FEMALE; GALACTOSE; GALACTOSYLTRANSFERASES; GLYCOPROTEINS; GLYCOSYLATION; GUINEA PIGS; MACROPHAGES; MYELIN BASIC PROTEIN; NERVE TISSUE PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, INBRED LEW; SPINAL CORD; UP-REGULATION;

MLCS; MLOWN;

EID: 84880575138     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9824-3     Document Type: Article

References (58)

1. Amado M, Almeida R, Schwientek T, Clausen H (1999) Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. Biochim Biophys Acta 1473:35-53
2. Appeddu PA, Shur BD (1994a) Control of stable lamellipodia formation by expression of cell surface beta 1,4-galactosyltransferase cytoplasmic domains. J Cell Sci 107:2535-2545
3. Appeddu PA, Shur BD (1994b) Molecular analysis of cell surface beta-1,4-galactosyltransferase function during cell migration. Proc Natl Acad Sci USA 91:2095-2099
4. Asano M, Nakae S, Kotani N, Shirafuji N, Nambu A, Hashimoto N, Kawashima H, Hirose M, Miyasaka M, Takasaki S, Iwakura Y (2003) Impaired selectin-ligand biosynthesis and reduced inflammatory responses in beta-1,4- galactosyltransferase-I-deficient mice. Blood 102:1678-1685
5. Borsig L, Kleene R, Dinter A, Berger EG (1996) Immunodetection of alpha 1-3 fucosyltransferase (FucT-V). Eur J Cell Biol 70:42-53
6. Brand-Schieber E, Werner P, Scemes E (2005) Connexin43, the major gap junction protein of astrocytes, is down-regulated in inflamed white matter in an animal model of multiple sclerosis. J Neurosci Res 80(6):798-808
7. Butcher EC (1991) Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67:1033
8. Chiaretti A, Genovese O, Aloe L, Antonelli A, Piastra M, Polidori G, Di Rocco C (2005) Interleukin 1beta and interleukin 6 relationship with pediatric head trauma severity and outcome. Childs Nerv. Syst. 21:185-193
9. Clarkson AN, Rahman R, Appleton I (2004) Inflammation and autoimmunity as a central theme in neurodegenerative disorders: fact or fiction? Curr Opin Investig Drugs 5:706-713
10. Close BE, Colley KJ (1998) In vivo autopolysialylation and localization of the polysialyltransferases PST and STX. J Biol Chem 273:34586-34593
11. Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T (1995) Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. FASEB J 9:899-909
12. Dijkstra CD, Dopp EA, Joling P, Kraal G (1985) The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3. Immunology 54:589-599
13. Eckstein DJ, Shur BD (1992) Cell surface beta-1,4-galactosyltransferase is associated with the detergent-insoluble cytoskeleton on migrating mesenchymal cells. Exp Cell Res 201:83-90
14. Eikelenboom P, Veerhuis R (1999) The importance of inflammatory mechanisms for the development of Alzheimer's disease. Exp Gerontol 34:453-461
15. Engelhardt B, Ransohoff RM (2005) The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms. Trends Immunol 26:485-495
16. Evans SC, Lopez LC, Shur BD (1993) Dominant negative mutation in cell surface beta 1,4-galactosyltransferase inhibits cell-cell and cellmatrix interactions. J Cell Biol 120:1045-1057
17. Ewing C, Bernard CCA (1998) Insight into the aetiology and pathogenesis of multiple sclerosis. Immunol Cell Biol 76:47-54
18. Glasgow LR, Paulson JC, Hill RL (1977) Systematic purification of five glycosidases from Streptococcus (Diplococcus) pneumoniae. J Biol Chem 252:8615-8623
19. Hamada Y, Ikata T, Katoh S, Nakauchi K, Niwa M, Kawai Y, Fukuzawa K (1996) Involvement of an intercellular adhesion molecule 1-dependent pathway in the pathogenesis of secondary changes after spinal cord injury in rats. J Neurochem 66:1525-1531
20. Hammarberg H, Lidman O, Lundberg C, Eltayeb SY, Gielen AW, Muhallab S, Svenningsson A, Linda H, van Der Meide PH, Cullheim S, Olsson T, Piehl F (2000) Neuroprotection by encephalomyelitis: rescue of mechanically injured neurons and neurotrophin production by CNS-infiltrating T and natural killer cells. J Neurosci 20:5283-5291
21. Hathaway HJ, Evans SC, Shur BD (2003) Mutational analysis of the cytoplasmic domain of beta-1,4-galactosyltransferase I: influence of phosphorylation on cell surface expression. J Cell Sci 116:4319-4330
22. Hemmer B, Kieseier B, Cepok S, Hartung HP (2003) New immunopathologic insights into multiple sclerosis. Curr Neurol Neurosci Rep 3:246-255
23. Hennet T (2002) The galactosyltransferase family. Cell Mol Life Sci 59:1081-1095
24. Hohlfeld R, Wekerle H (2001) Immunological update on multiple sclerosis. Curr Opin Neurol 14:299-304
25. Honegger CG, Langemann H (1989) Some pathophysiological aspects of experimental autoimmune encephalomyelitis. Schweiz Rundschau Med Prax 78:964-966
26. Huang D, Han Y, Rani MR, Glabinski A, Trebst C, Sørensen T, Tani M, Wang J, Chien P, O'Bryan S, Bielecki B, Zhou ZL, Majumder S, Ransohoff RM (2000) Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation. Immunol Rev 177:52-67
27. Koshinaga M, Whittemore SR (1995) The temporal and spatial activation of microglia in fiber tracts undergoing anterograde and retrograde degeneration following spinal cord lesion. J Neurotrauma 12:209-222
28. Lowe JB (1997) Selectin ligands, leukocyte trafficking, and fucosyltransferase genes. Kidney Int 51:1418-1426
29. Luster AD (1998) Chemokines - chemotactic cytokines that mediate inflammation. N Engl J Med 338:436-445
30. Mackay CR, Imhof BA (1993) Cell adhesion in the immune system. Immunol Today 14:99-102
31. Mandel U, Hassan H, Therkildsen MH, Rygaard J, Jakobsen MH, Juhl BR, Dabelsteen E, Clausen H (1999) Expression of polypeptide GalNAc-transferases in stratified epithelia and squamous cell carcinomas: immunohistological evaluation using monoclonal antibodies to three members of the GalNAc-transferase family. Glycobiology 9:43-52
32. Mantovani A, Bussolino F, Introna M (1997) Cytokine regulation of endothelial cell function: from molecular level to the bedside. Immunol Today 18:231-240
33. Marker PC, Stephan JP, Lee J, Bald L, Mather JP, Cunha GR (2001) Fucosyltransferase 1 and H-type complex carbohydrates modulate epithelial cell proliferation during prostatic branching morphogenesis. Dev Biol 233:95-108
34. McEver RP, Moore KL, Cummings RD (1995) Leukocyte trafficking mediated by selectin-carbohydrate interactions. J Biol Chem 270:11025-11028
35. Means ED, Anderson DK (1983) Neuronophagia by leukocytes in experimental spinal cord injury. J Neuropathol Exp Neurol 42:707-719
36. Miller SD, Karpus WJ (1994) The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases. Immunol Today 15:356-361
37. Mori R, Kondo T, Nishie T, Ohshima T, Asano M (2004) Impairment of skin wound healing in beta-1,4-galactosyltransferase-deficient mice with reduced leukocyte recruitment. Am J Pathol 164(4):1303-14
38. Niu S, Fei M, Cheng C, Yan M, Gao S, Chen M, Wang H, Li X, Yu X, Qian J, Qin J, Zhao J, Gu J, Shen A (2008) Altered beta-1,4-galactosyltransferase I expression during early inflammation after spinal cord contusion injury. J Chem Neuroanat 35:245-256
39. Owens T (2003) The enigma of multiple sclerosis: inflammation and neurodegeneration cause heterogeneous dysfunction and damage. Curr Opin Neurol 16:259-265
40. Popovich PG, Wei P, Stokes BT (1997) Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats. J Comp Neurol 377:443-464
41. Qian J, Cheng C, Liu H, Chen J, Yan M, Niu S, Qin J, Sun L, Liu L, Gu J, Shen A (2007) Expression of beta-1,4-galactosyltransferase-I in rat during inflammation. Inflammation 30:59-68
42. Raine CS, Cannella B, Hauser SL, Genain CP (1999) Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: a case for antigen-specific antibody mediation. Ann Neurol 46:144-160
43. Rajan AJ, Gao YL, Raine CS, Brosnan CF (1996) A pathogenic role for gamma delta T cells in relapsing-remitting experimental autoimmune encephalomyelitiin the SJL mouse. J Immunol 157:941-949
44. Secor VH, Secor WE, Gutekunst CA, Brown MA (2000) Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis. J Exp Med 191:813-822
45. Shen A, Chen J, Qian J, Zhu J, Hu L, Yan M, Zhou D, Gao Y, Yang J, Ding F, Cheng C (2009) Elevated beta1,4-galactosyltransferase-I induced by the intraspinal injection of lipopolysaccharide. Glycoconj J 26:19-31
46. Shur BD, Evans S, Lu Q (1998) Cell surface galactosyltransferase: current issues. Glycoconj J 15:537-548
47. Sospedra M, Martin R (2005) Immunology of multiple sclerosis. Annu Rev Immunol 23:683-747
48. Springer TA (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301
49. Stampachiacchiere B, Aloe L (2005) Differential modulatory effect of NGF on MHC class I and class II expression in spinal cord cells of EAE rats. J Neuroimmunol 169:20-30
50. Stoolman LM (1993) Adhesion molecules involved in leukocyte recruitment and lymphocyte recirculation. Chest 103:79S-86S
51. Taoka Y, Okajima K, Uchiba M, Murakami K, Kushimoto S, Johno M, Naruo M, Okabe H, Takatsuki K (1997) Role of neutrophils in spinal cord injury in the rat. Neuroscience 79:1177-1182
52. Teismann P, Schulz JB (2004) Cellular pathology of Parkinson's disease: astrocytes, microglia and inflammation. Cell Tissue Res 318:149-161
53. Venkatesh YP, Lambert JM (1997) Galactose-induced dimerization of blocked ricin at acidic pH: evidence for a third galactose-binding site in ricin B-chain. Glycobiology 7:329-335
54. Villarroya H, Marie Y, Ouallet JC, Le Saux F, Tchélingérian JL, Baumann JL (1997) Expression of TNF alpha in central neurons of Lewis rat spinal cord after EAE induction. J Neurosci Res 49(5):592-599
55. Xu JA, Hsu CY, Liu TH, Hogan EL, Perot PL Jr, Tai HH (1990) Leukotriene B4 release and polymorphonuclear cell infiltration in spinal cord injury. J Neurochem 55:907-912
56. Yan M, Xia C, Niu S, Shao X, Cheng C, Zhao J, Shen A (2007) The role of TNF-alpha and its receptors in the production of beta-1,4 galactosyltransferase I and V mRNAs by rat primary astrocytes. J Mol Neurosci 33:155-162
57. Yan M, Xia C, Niu S, Cheng C, Shao X, Shen A (2008) The role of TNF-alpha and its receptors in the production of beta-1,4-galactosyltransferase I mRNA by rat primary Type-2 astrocytes. Cell Mol Neurobiol 28(2):223-236
58. Zingarelli B, Hake PW, Yang Z, O'Connor M, Denenberg A, Wong HR (2002) Absence of inducible nitric oxide synthase modulates early reperfusion- induced NF-kappaB and AP-1 activation and enhances myocardial damage. FASEB J 16:327-342