Cyclooxygenase-2-derived prostaglandin E2 promotes injury-induced vascular neointimal hyperplasia through the E-prostanoid 3 receptor

Circulation Research

Volumn 113, Issue 2, 2013, Pages 104-114

  Zhang, Jian ^a   Zou, Fangfang ^a,b   Tang, Juan ^a   Zhang, Qianqian ^a   Gong, Yanjun ^a   Wang, Qingsong ^a   Shen, Yujun ^a   Xiong, Lixia ^b   Breyer, Richard M ^c   Lazarus, Michael ^d   Funk, Colin D ^e   Yu, Ying ^a  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^b NANCHANG UNIVERSITY   (China)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d OSAKA BIOSCIENCE INSTITUTE   (Japan)

^e QUEEN S UNIVERSITY   (Canada)

Author keywords

EP3; neointima formation; polarity; prostaglandin E2; vascular smooth muscle cell migration

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GLYCOGEN SYNTHASE KINASE 3BETA; GUANOSINE TRIPHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN E RECEPTOR 3; PROSTAGLANDIN E RECEPTOR 3 ALPHA; PROSTAGLANDIN E RECEPTOR 3 BETA; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL REACTIVITY; CELL MIGRATION; CELL POLARITY; CONTROLLED STUDY; ENZYME ACTIVITY; KNOCKOUT MOUSE; MOUSE; NEOINTIMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESTENOSIS; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR NEOINTIMAL HYPERPLASIA; VASCULAR SMOOTH MUSCLE;

EP3; NEOINTIMA FORMATION; POLARITY; PROSTAGLANDIN E2; VASCULAR SMOOTH MUSCLE CELL MIGRATION;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; FEMORAL ARTERY; HYPERPLASIA; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; NEOINTIMA; RECEPTORS, PROSTAGLANDIN E, EP3 SUBTYPE;

EID: 84880548444     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.113.301033     Document Type: Article

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