Impaired lipid accumulation in the liver of Tsc2-heterozygous mice during liver regeneration

Biochemical and Biophysical Research Communications

Volumn 437, Issue 1, 2013, Pages 146-150

  Obayashi, Yoko ^a   Campbell, Jean S ^a   Fausto, Nelson ^a   Yeung, Raymond S ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Lipid; Liver regeneration; MTOR; P70S6K; TSC2; Tuberin

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; TUBERIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENERGY BALANCE; ENERGY RESOURCE; ENZYME ACTIVATION; HETEROZYGOTE; HYPOTHESIS; IMMUNOPRECIPITATION; LIPID LIVER LEVEL; LIPID STORAGE; LIPID VESICLE; LIPIDOSIS; LIVER REGENERATION; MALE; MORTALITY; MOUSE; NONHUMAN; PARTIAL HEPATECTOMY; PH; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SHAM PROCEDURE; WESTERN BLOTTING; WILD TYPE;

4-(2-AMINOETHYL) BENZENESULFONYL FLUORIDE HYDROCHLORIDE; 5′AMP-ACTIVATED PROTEIN KINASE; AEBSF; AMPK; C57 BLACK 6; C57BL/6; ERK; EXTRACELLULAR SIGNAL-REGULATED KINASE; GAP; GTPASE-ACTIVATING PROTEIN; LIPID; LIVER REGENERATION; MAMMALIAN TARGET OF RAPAMYCIN; MAPK; MITOGEN-ACTIVATED PROTEIN KINASE; MTOR; P70 RIBOSOMAL S6 KINASE; P70S6K; P90 RIBOSOMAL S6 KINASE; P90 RSK; PARTIAL HEPATECTOMY; PH; RAS HOMOLOG ENRICHED IN BRAIN; RHEB; SH; SHAM OPERATION; TSC; TSC2; TUBERIN; TUBEROUS SCLEROSIS;

ANIMALS; BODY WEIGHT; ENZYME ACTIVATION; HEPATECTOMY; HETEROZYGOTE; LIPID METABOLISM; LIVER; LIVER REGENERATION; MALE; MICE; MICE, INBRED C57BL; ORGAN SIZE; PHOSPHORYLATION; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TIME FACTORS; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

MUS;

EID: 84880511015     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.06.056     Document Type: Article

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