메뉴 건너뛰기




Volumn 45, Issue 4, 2010, Pages 468-476

Propranolol impairs liver regeneration after partial hepatectomy in C57Bl/6-mice by transient attenuation of hepatic lipid accumulation and increased apoptosis

Author keywords

Beta adrenergic inhibition; Hepatic fat accumulation; Hepatocyte transplantation; Liver regeneration; Partial hepatectomy

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLINE; KI 67 ANTIGEN; LIPID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROPRANOLOL; TRIACYLGLYCEROL;

EID: 77949907112     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365520903583848     Document Type: Article
Times cited : (35)

References (40)
  • 1
    • 33646021275 scopus 로고    scopus 로고
    • Mild hepatic steatosis is not a major risk factor for hepatectomy and regenerative power is not impaired
    • Cho JY, Suh KS, Kwon CH, Yi NJ, Lee KU. Mild hepatic steatosis is not a major risk factor for hepatectomy and regenerative power is not impaired. Surgery 2006;139:508-515
    • (2006) Surgery , vol.139 , pp. 508-515
    • Cho, J.Y.1    Suh, K.S.2    Kwon, C.H.3    Yi, N.J.4    Lee, K.U.5
  • 2
    • 33845948392 scopus 로고    scopus 로고
    • Severe steatosis increases hepatocellular injury and impairs liver regeneration in a rat model of partial hepatectomy
    • Vetelainen R, van Vliet AK, van Gulik TM. Severe steatosis increases hepatocellular injury and impairs liver regeneration in a rat model of partial hepatectomy. Ann Surg 2007; 245:44-50.
    • (2007) Ann Surg , vol.245 , pp. 44-50
    • Vetelainen, R.1    Van Vliet, A.K.2    Van Gulik, T.M.3
  • 4
    • 0033985856 scopus 로고    scopus 로고
    • Failure of regeneration of the steatotic rat liver: Disruption at two different levels in the regeneration pathway
    • Selzner M, Clavien PA. Failure of regeneration of the steatotic rat liver: disruption at two different levels in the regeneration pathway. Hepatology 2000;31:35-42.
    • (2000) Hepatology , vol.31 , pp. 35-42
    • Selzner, M.1    Clavien, P.A.2
  • 6
    • 10644240816 scopus 로고    scopus 로고
    • Probing Prometheus fat fueling the fire?
    • Farrell GC. Probing Prometheus: fat fueling the fire? Hepatology 2004;40:1252-1255
    • (2004) Hepatology , vol.40 , pp. 1252-1255
    • Farrell, G.C.1
  • 7
    • 36349029605 scopus 로고    scopus 로고
    • Had Prometheus known, would he have preferred to be obese?
    • Mitchell C, Gilgenkrantz H. Had Prometheus known, would he have preferred to be obese? J Gastroenterol Hepatol 2007;22:2053-2054
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 2053-2054
    • Mitchell, C.1    Gilgenkrantz, H.2
  • 8
    • 10644248333 scopus 로고    scopus 로고
    • Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice
    • Shteyer E, Liao Y, Muglia LJ, Hruz PW, Rudnick DA. Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice. Hepatology 2004;40:1322-1332
    • (2004) Hepatology , vol.40 , pp. 1322-1332
    • Shteyer, E.1    Liao, Y.2    Muglia, L.J.3    Hruz, P.W.4    Rudnick, D.A.5
  • 9
    • 33748759828 scopus 로고    scopus 로고
    • Cell biology. A metabolic push to proliferate
    • Brasaemle DL. Cell biology. A metabolic push to proliferate. Science 2006;313:1581-1582
    • (2006) Science , vol.313 , pp. 1581-1582
    • Brasaemle, D.L.1
  • 10
    • 0021998372 scopus 로고
    • Alpha-adrenergic regulation of the activity of thymidylate synthetase and thymidine kinase during liver regeneration after partial hepatectomy
    • Nakata R, Tsukamoto I, Nanme M, Makino S, Miyoshi M, Kojo S. Alpha-adrenergic regulation of the activity of thymidylate synthetase and thymidine kinase during liver regeneration after partial hepatectomy. Eur J Pharmacol 1985; 114:355-360
    • (1985) Eur J Pharmacol , vol.114 , pp. 355-360
    • Nakata, R.1    Tsukamoto, I.2    Nanme, M.3    Makino, S.4    Miyoshi, M.5    Kojo, S.6
  • 11
    • 0030582209 scopus 로고    scopus 로고
    • Control of thymidine kinase during liver regeneration after partial hepatectomy
    • Tsukamoto I, Wakabayashi M, Takebayashi K, Nomura S. Control of thymidine kinase during liver regeneration after partial hepatectomy. Biochim Biophys Acta 1996;1290: 267-272
    • (1996) Biochim Biophys Acta , vol.1290 , pp. 267-272
    • Tsukamoto, I.1    Wakabayashi, M.2    Takebayashi, K.3    Nomura, S.4
  • 12
    • 0031419443 scopus 로고    scopus 로고
    • Lee SK. dlpropranolol negatively regulates the transcription of proliferating cell nuclear antigen (PCNA)-gene and thereby suppresses DNA synthesis in regenerating rat liver
    • Hong JH, Hwang ES, Lee CH, Lee YH, Lee SK. dlpropranolol negatively regulates the transcription of proliferating cell nuclear antigen (PCNA)-gene and thereby suppresses DNA synthesis in regenerating rat liver. Biochem Mol Biol Int 1997;42:103-112
    • (1997) Biochem Mol Biol Int , vol.42 , pp. 103-112
    • Hong, J.H.1    Hwang, E.S.2    Lee, C.H.3    Lee, Y.H.4
  • 13
    • 0022341001 scopus 로고
    • The possible cyclic AMPdependence of an early prereplicative event that determines mitosis in regenerating rat liver
    • Rixon RH, Whitfield JF. The possible cyclic AMPdependence of an early prereplicative event that determines mitosis in regenerating rat liver. J Cell Physiol 1985;124: 397-402.
    • (1985) J Cell Physiol , vol.124 , pp. 397-402
    • Rixon, R.H.1    Whitfield, J.F.2
  • 14
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen PO. Preparation of isolated rat liver cells. Methods Cell Biol 1976;13:29-83.
    • (1976) Methods Cell Biol , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 15
    • 0025297413 scopus 로고
    • Effect of epidermal growth factor on the expression of protooncogenes c-myc and c-Ha-ras in short-term primary hepatocyte culture
    • Kost DP, Michalopoulos GK. Effect of epidermal growth factor on the expression of protooncogenes c-myc and c-Ha-ras in short-term primary hepatocyte culture. J Cell Physiol 1990;144:122-127
    • (1990) J Cell Physiol , vol.144 , pp. 122-127
    • Kost, D.P.1    Michalopoulos, G.K.2
  • 16
    • 0029928703 scopus 로고    scopus 로고
    • Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium
    • Block GD, Locker J, Bowen WC, Petersen BE, Katyal S, Strom SC, et al. Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium. J Cell Biol 1996; 132:1133-1149
    • (1996) J Cell Biol , vol.132 , pp. 1133-1149
    • Block, G.D.1    Locker, J.2    Bowen, W.C.3    Petersen, B.E.4    Katyal, S.5    Strom, S.C.6
  • 17
    • 0034607108 scopus 로고    scopus 로고
    • Serum-free, long-term cultures of human hepatocytes: Maintenance of cell morphology, transcription factors, and liver-specific functions
    • Runge D, Runge DM, Jager D, Lubecki KA, Beer Stolz D, Karathanasis S, et al. Serum-free, long-term cultures of human hepatocytes: maintenance of cell morphology, transcription factors, and liver-specific functions. Biochem Biophys Res Commun 2000;269:46-53.
    • (2000) Biochem Biophys Res Commun , vol.269 , pp. 46-53
    • Runge, D.1    Runge, D.M.2    Jager, D.3    Lubecki, K.A.4    Beer Stolz, D.5    Karathanasis, S.6
  • 18
    • 0036468677 scopus 로고    scopus 로고
    • Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
    • Lois C, Hong EJ, Pease S, Brown EJ, Baltimore D. Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science 2002;295: 868-872
    • (2002) Science , vol.295 , pp. 868-872
    • Lois, C.1    Hong, E.J.2    Pease, S.3    Brown, E.J.4    Baltimore, D.5
  • 19
    • 34547281072 scopus 로고    scopus 로고
    • Hepatocyte differentiation of mesenchymal stem cells from rat peritoneal adipose tissue in vitro and in vivo
    • Sgodda M, Aurich H, Kleist S, Aurich I, Konig S, Dollinger MM, et al. Hepatocyte differentiation of mesenchymal stem cells from rat peritoneal adipose tissue in vitro and in vivo. Exp Cell Res 2007;313:2875-2886
    • (2007) Exp Cell Res , vol.313 , pp. 2875-2886
    • Sgodda, M.1    Aurich, H.2    Kleist, S.3    Aurich, I.4    Konig, S.5    Dollinger, M.M.6
  • 20
    • 0027405261 scopus 로고
    • Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts
    • Carr TP, Andresen CJ, Rudel LL. Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts. Clin Biochem 1993;26:39-42.
    • (1993) Clin Biochem , vol.26 , pp. 39-42
    • Carr, T.P.1    Andresen, C.J.2    Rudel, L.L.3
  • 22
    • 0034030450 scopus 로고    scopus 로고
    • The extent of synchronous initiation and termination of DNA synthesis in regenerating mouse liver is dependent on connexin32 expressing gap junctions
    • Temme A, Ott T, Dombrowski F, Willecke K. The extent of synchronous initiation and termination of DNA synthesis in regenerating mouse liver is dependent on connexin32 expressing gap junctions. J Hepatol 2000;32:627-635
    • (2000) J Hepatol , vol.32 , pp. 627-635
    • Temme, A.1    Ott, T.2    Dombrowski, F.3    Willecke, K.4
  • 23
    • 33646756587 scopus 로고    scopus 로고
    • Identification of factors contributing to hepatomegaly in severely burned children
    • Barrow RE, Hawkins HK, Aarsland A, Cox R, Rosenblatt J, Barrow LN, et al. Identification of factors contributing to hepatomegaly in severely burned children. Shock 2005;24: 523-528
    • (2005) Shock , vol.24 , pp. 523-528
    • Barrow, R.E.1    Hawkins, H.K.2    Aarsland, A.3    Cox, R.4    Rosenblatt, J.5    Barrow, L.N.6
  • 24
    • 0029947931 scopus 로고    scopus 로고
    • Beta-blockade lowers peripheral lipolysis in burn patients receiving growth hormone. Rate of hepatic very low density lipoprotein triglyceride secretion remains unchanged
    • Aarsland A, Chinkes D, Wolfe RR, Barrow RE, Nelson SO, Pierre E, et al. Beta-blockade lowers peripheral lipolysis in burn patients receiving growth hormone. Rate of hepatic very low density lipoprotein triglyceride secretion remains unchanged. Ann Surg 1996;223:777-787
    • (1996) Ann Surg , vol.223 , pp. 777-787
    • Aarsland, A.1    Chinkes, D.2    Wolfe, R.R.3    Barrow, R.E.4    Nelson, S.O.5    Pierre, E.6
  • 25
    • 0036325113 scopus 로고    scopus 로고
    • Propranolol decreases splanchnic triacylglycerol storage in burn patients receiving a high-carbohydrate diet
    • Morio B, Irtun O, Herndon DN, Wolfe RR. Propranolol decreases splanchnic triacylglycerol storage in burn patients receiving a high-carbohydrate diet. Ann Surg 2002;236: 218-225
    • (2002) Ann Surg , vol.236 , pp. 218-225
    • Morio, B.1    Irtun, O.2    Herndon, D.N.3    Wolfe, R.R.4
  • 27
    • 59849093845 scopus 로고    scopus 로고
    • Mild hypothermia does not affect liver regeneration after partial hepatectomy in mice
    • Arab JP, Pizarro M, Solis N, Sun H, Thevananther S, Arrese M. Mild hypothermia does not affect liver regeneration after partial hepatectomy in mice. Liver Int 2009; 29:344-348
    • (2009) Liver Int , vol.29 , pp. 344-348
    • Arab, J.P.1    Pizarro, M.2    Solis, N.3    Sun, H.4    Thevananther, S.5    Arrese, M.6
  • 28
    • 11144352722 scopus 로고    scopus 로고
    • Cdk1 and Cdk2 complexes (cyclin dependent kinases) in apoptosis: A role beyond the cell cycle
    • Golsteyn RM. Cdk1 and Cdk2 complexes (cyclin dependent kinases) in apoptosis: a role beyond the cell cycle. Cancer Lett 2005;217:129-138
    • (2005) Cancer Lett , vol.217 , pp. 129-138
    • Golsteyn, R.M.1
  • 29
    • 0036172085 scopus 로고    scopus 로고
    • Recovery of liver mass without proliferation of hepatocytes after partial hepatectomy in Skp2-deficient mice
    • Minamishima YA, Nakayama K, Nakayama K. Recovery of liver mass without proliferation of hepatocytes after partial hepatectomy in Skp2-deficient mice. Cancer Res 2002; 62:995-999
    • (2002) Cancer Res , vol.62 , pp. 995-999
    • Minamishima, Y.A.1    Nakayama, K.2    Nakayama, K.3
  • 30
    • 67650348339 scopus 로고    scopus 로고
    • Evaluation of the metabolism of propranolol by linear ion trap technology in mouse, rat, dog, monkey, and human cryopreserved hepatocytes
    • Baughman TM, Talarico CL, Soglia JR. Evaluation of the metabolism of propranolol by linear ion trap technology in mouse, rat, dog, monkey, and human cryopreserved hepatocytes. Rapid Commun Mass Spectrom 2009;23:2146-2150
    • (2009) Rapid Commun Mass Spectrom , vol.23 , pp. 2146-2150
    • Baughman, T.M.1    Talarico, C.L.2    Soglia, J.R.3
  • 31
    • 0018578890 scopus 로고
    • Pharmacokinetics of propranolol in the cat and comparisons with humans and three other species
    • Weidler DJ, Jallad NS, Garg DC, Wagner JG. Pharmacokinetics of propranolol in the cat and comparisons with humans and three other species. Res Commun Chem Pathol Pharmacol 1979;26:105-114
    • (1979) Res Commun Chem Pathol Pharmacol , vol.26 , pp. 105-114
    • Weidler, D.J.1    Jallad, N.S.2    Garg, D.C.3    Wagner, J.G.4
  • 32
    • 54449099984 scopus 로고    scopus 로고
    • Altered hepatic triglyceride content after partial hepatectomy without impaired liver regeneration in multiple murine genetic models
    • Newberry EP, Kennedy SM, Xie Y, Luo J, Stanley SE, Semenkovich CF. Altered hepatic triglyceride content after partial hepatectomy without impaired liver regeneration in multiple murine genetic models. Hepatology 2008;48:1097-1105
    • (2008) Hepatology , vol.48 , pp. 1097-1105
    • Newberry, E.P.1    Kennedy, S.M.2    Xie, Y.3    Luo, J.4    Stanley, S.E.5    Semenkovich, C.F.6
  • 35
    • 30944439355 scopus 로고    scopus 로고
    • Trimming the fat from liver regeneration
    • Rudnick AR. Trimming the fat from liver regeneration. Hepatology 2005;42:1001-1003
    • (2005) Hepatology , vol.42 , pp. 1001-1003
    • Rudnick, A.R.1
  • 36
    • 69349105535 scopus 로고    scopus 로고
    • Adiponectin deficiency impairs liver regeneration through attenuating STAT3 phosphorylation in mice
    • Shu RZ, Zhang F, Wang F, Feng DC, Li XH, Ren WH, et al. Adiponectin deficiency impairs liver regeneration through attenuating STAT3 phosphorylation in mice. Lab Invest 2009;89:1043-1052
    • (2009) Lab Invest , vol.89 , pp. 1043-1052
    • Shu, R.Z.1    Zhang, F.2    Wang, F.3    Feng, D.C.4    Li, X.H.5    Ren, W.H.6
  • 38
    • 26644468647 scopus 로고    scopus 로고
    • Hepatocyte transplantation
    • (in German)
    • Christ B, Fleig WE. Hepatocyte transplantation. Med Klin (Munich) 2005;100:650-655 (in German).
    • (2005) Med Klin (Munich) , vol.100 , pp. 650-655
    • Christ, B.1    Fleig, W.E.2
  • 39
    • 33746908526 scopus 로고    scopus 로고
    • Present status and perspectives of cell-based therapies for liver diseases
    • Nussler A, Konig S, Ott M, Sokal E, Christ B, Thasler W, et al. Present status and perspectives of cell-based therapies for liver diseases. J Hepatol 2006;45:144-159
    • (2006) J Hepatol , vol.45 , pp. 144-159
    • Nussler, A.1    Konig, S.2    Ott, M.3    Sokal, E.4    Christ, B.5    Thasler, W.6
  • 40
    • 0344142526 scopus 로고    scopus 로고
    • Hepatocyte transplantation for the treatment of human disease
    • Strom SC, Chowdhury JR, Fox IJ. Hepatocyte transplantation for the treatment of human disease. Semin Liver Dis 1999;19:39-48.
    • (1999) Semin Liver Dis , vol.19 , pp. 39-48
    • Strom, S.C.1    Chowdhury, J.R.2    Fox, I.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.