Biosynthesis of nucleoside analogues via thermostable nucleoside phosphorylase

Applied Microbiology and Biotechnology

Volumn 97, Issue 15, 2013, Pages 6769-6778

  Zhu, Shaozhou ^a   Song, Dawei ^a   Gong, Cuiyu ^a   Tang, Pingwah ^a   Li, Xingzhou ^b   Wang, Jianjun ^c   Zheng, Guojun ^a  

^a BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

^b BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

^c INSTITUTE OF MICROBIOLOGY   (China)

Author keywords

Biosynthesis; Nucleoside analogues; Purine nucleoside phosphorylase; Thermostable; Uridine phosphorylase

Indexed keywords

HIGH-TEMPERATURE REACTION; NUCLEOSIDE ANALOGUES; NUCLEOSIDE PHOSPHORYLASE; OPTIMUM TEMPERATURE; PURINE NUCLEOSIDE PHOSPHORYLASE; SUBSTRATE SPECIFICITY; THERMOSTABLE; URIDINE PHOSPHORYLASE;

BIOCHEMISTRY; BIOSYNTHESIS; ENZYMES; ESCHERICHIA COLI; PHOSPHORYLATION;

BIOMOLECULES;

NUCLEOSIDE ANALOG; NUCLEOSIDE PHOSPHORYLASE; PURINE NUCLEOSIDE PHOSPHORYLASE; URIDINE PHOSPHORYLASE; ZIDOVUDINE;

CATALYSIS; CATALYST; COLIFORM BACTERIUM; DRUG; ENZYME ACTIVITY; NUMERICAL MODEL; OXIC CONDITIONS; SUBSTRATE; TEMPERATURE EFFECT;

ANTIVIRAL THERAPY; ARTICLE; BIOSYNTHESIS; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME SPECIFICITY; ESCHERICHIA COLI; HIGH TEMPERATURE PROCEDURES; NONHUMAN; PROTEIN EXPRESSION; THERMOSTABILITY;

CLONING, MOLECULAR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME STABILITY; KINETICS; MODELS, MOLECULAR; PENTOSYLTRANSFERASES; SUBSTRATE SPECIFICITY;

AEROPYRUM PERNIX; CRENARCHAEOTA; ESCHERICHIA COLI;

EID: 84880507667     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4542-x     Document Type: Article

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