Enantioselective synthesis and antiviral activity of purine and pyrimidine cyclopentenyl C-nucleosides

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 2, 2007, Pages 839-846

  Rao, Jagadeeshwar R ^a   Schinazi, Raymond F ^b   Chu, Chung K ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antiviral activity; Carbocyclic C nucleosides; Enantioselective synthesis

Indexed keywords

2,3 (ISOPROPYLIDENEDIOXY) 4 (TRITYLOXYMETHYL) 4 CYCLOPENTEN 1 OL; 5 (2',3' DIHYDROXY 4' CYCLOPENTEN 1' YL)URACIL; 5 (2',3' DIHYDROXY 4' HYDROXYMETHYL 4' CYCLOPENTEN 1' YL)ISOCYTOSINE; 9 (2',3' DIHYDROXY 4' HYDROXYMETHYL 4' CYCLOPENTEN 1' YL)DEAZAGUANOSINE; 9 DEAZANEPLANOCIN A; ANTIVIRUS AGENT; CYCLOPENTENE DERIVATIVE; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; RIBOSE; ZIDOVUDINE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; COWPOX VIRUS; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG SENSITIVITY; DRUG SYNTHESIS; ENANTIOSELECTIVITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IN VITRO STUDY; NONHUMAN; PUNTA TORO VIRUS; SARS CORONAVIRUS; VIRUS; WEST NILE FLAVIVIRUS;

ANIMALS; ANTI-HIV AGENTS; ANTIVIRAL AGENTS; CERCOPITHECUS AETHIOPS; CYCLOPENTANES; DRUG SCREENING ASSAYS, ANTITUMOR; HIV-1; HUMANS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOSIDES; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM; VERO CELLS; VIRUSES;

COWPOX VIRUS;

EID: 33845342222     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.10.043     Document Type: Article

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