Nifedipine inhibits angiotensin II-induced cardiac fibrosis via downregulating Nox4-derived ROS generation and suppressing ERK1/2, JNK signaling pathways

Pharmazie

Volumn 68, Issue 6, 2013, Pages 435-441

  Jia, Yanyan ^a   Xu, Jian ^a   Yu, Yang ^a   Guo, Jinlei ^a   Liu, Peiqing ^a   Chen, Shaorui ^a   Jiang, Jianmin ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; CONNECTIVE TISSUE GROWTH FACTOR; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NIFEDIPINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CELL PROLIFERATION; DOWN REGULATION; EXTRACELLULAR MATRIX; FIBROBLAST; HEART MUSCLE FIBROSIS; UPREGULATION;

ACTINS; ANGIOTENSIN II; ANIMALS; BLOTTING, WESTERN; CALCIUM CHANNEL BLOCKERS; CALCIUM SIGNALING; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SEPARATION; CONNECTIVE TISSUE GROWTH FACTOR; DOWN-REGULATION; FIBRONECTINS; FIBROSIS; FLUORESCENT ANTIBODY TECHNIQUE; HEART DISEASES; MALE; MAP KINASE SIGNALING SYSTEM; NADPH OXIDASE; NIFEDIPINE; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; VASOCONSTRICTOR AGENTS;

EID: 84880491983     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2013.2873     Document Type: Article

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