-
1
-
-
0033948968
-
Protective effect of melatonin against the 1-methyl-4-phenylpyridinium-induced inhibition of complex I of the mitochondrial respiratory chain
-
Absi E., Ayala A., Machado A. and Parrado J. (2000). Protective effect of melatonin against the 1-methyl-4-phenylpyridinium-induced inhibition of complex I of the mitochondrial respiratory chain. J. Pineal Res. 29, 40-47.
-
(2000)
J. Pineal Res.
, vol.29
, pp. 40-47
-
-
Absi, E.1
Ayala, A.2
McHado, A.3
Parrado, J.4
-
2
-
-
34247502759
-
Melatonin: Effects on dopaminergic and serotonergic neurons of the caudate nucleus of the striatum of male Syrian hamsters
-
Alexiuk N.A. and Vriend J. (2007). Melatonin: effects on dopaminergic and serotonergic neurons of the caudate nucleus of the striatum of male Syrian hamsters. J. Neural Transm. 114, 549-554.
-
(2007)
J. Neural Transm.
, vol.114
, pp. 549-554
-
-
Alexiuk, N.A.1
Vriend, J.2
-
3
-
-
39449113020
-
Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and alphasynuclein-deleted mice
-
Alvarez-Fischer D., Henze C., Strenzke C., Westrich J., Ferger B., Hoglinger G.U., Oertel W.H. and Hartmann A. (2008). Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and alphasynuclein-deleted mice. Exp. Neurol. 210, 182-193.
-
(2008)
Exp. Neurol.
, vol.210
, pp. 182-193
-
-
Alvarez-Fischer, D.1
Henze, C.2
Strenzke, C.3
Westrich, J.4
Ferger, B.5
Hoglinger, G.U.6
Oertel, W.H.7
Hartmann, A.8
-
4
-
-
0034469172
-
DNA-dependent protein kinase is not required for efficient lentivirus integration
-
Baekelandt V., Claeys A., Cherepanov P., De Clercq E., De Strooper B., Nuttin B. and Debyser Z. (2000). DNA-dependent protein kinase is not required for efficient lentivirus integration. J. Virol. 74, 11278-11285.
-
(2000)
J. Virol.
, vol.74
, pp. 11278-11285
-
-
Baekelandt, V.1
Claeys, A.2
Cherepanov, P.3
de Clercq, E.4
de Strooper, B.5
Nuttin, B.6
Debyser, Z.7
-
5
-
-
0036247444
-
Characterization of lentiviral vectormediated gene transfer in adult mouse brain
-
Baekelandt V. Claeys A., Eggermont K., Lauwers E., De Strooper B., Nuttin B. and Debyser Z. (2002). Characterization of lentiviral vectormediated gene transfer in adult mouse brain. Hum. Gene Ther. 13, 841-853.
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 841-853
-
-
Baekelandt, V.1
Claeys, A.2
Eggermont, K.3
Lauwers, E.4
de Strooper, B.5
Nuttin, B.6
Debyser, Z.7
-
6
-
-
0029032902
-
Melatonin stimulates brain glutathione peroxidase activity
-
Barlow-Walden L.R., Reiter R.J., Abe M., Pablos M., Menendez-Pelaez A., Chen L.D. and Poeggeler B. (1995). Melatonin stimulates brain glutathione peroxidase activity. Neurochem. Int. 26, 497-502.
-
(1995)
Neurochem. Int.
, vol.26
, pp. 497-502
-
-
Barlow-Walden, L.R.1
Reiter, R.J.2
Abe, M.3
Pablos, M.4
Menendez-Pelaez, A.5
Chen, L.D.6
Poeggeler, B.7
-
7
-
-
0343517507
-
Lentiviral vectors as a gene delivery system in the mouse midbrain: Cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF
-
Bensadoun J.C., Déglon N., Tseng J.L., Ridet J.L., Zurn A.D. and Aebischer P. (2000). Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF. Exp. Neurol. 164, 15-24.
-
(2000)
Exp. Neurol.
, vol.164
, pp. 15-24
-
-
Bensadoun, J.C.1
Déglon, N.2
Tseng, J.L.3
Ridet, J.L.4
Zurn, A.D.5
Aebischer, P.6
-
8
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R., Sherer T.B., MacKenzie G., Garcia-Osuna M., Panov A.V. and Greenamyre J.T. (2000). Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. 3, 1301-1306.
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
McKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
9
-
-
33745612296
-
Intersecting pathways to neurodegeneration in Parkinson's disease: Effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system
-
Betarbet R., Canet-Aviles R.M., Sherer T.B., Mastroberardino P.G., McLendon C., Kim J.H., Lund S., Na H.M., Taylor G., Bence N.F., Kopito R., Seo B.B., Yagi T., Yagi A., Klinefelter G., Cookson M.R. and Greenamyre J.T. (2006). Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system. Neurobiol. Dis. 22, 404-420.
-
(2006)
Neurobiol. Dis.
, vol.22
, pp. 404-420
-
-
Betarbet, R.1
Canet-Aviles, R.M.2
Sherer, T.B.3
Mastroberardino, P.G.4
McLendon, C.5
Kim, J.H.6
Lund, S.7
Na, H.M.8
Taylor, G.9
Bence, N.F.10
Kopito, R.11
Seo, B.B.12
Yagi, T.13
Yagi, A.14
Klinefelter, G.15
Cookson, M.R.16
Greenamyre, J.T.17
-
10
-
-
1842411367
-
Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector
-
Blömer U., Naldini L., Kafri T., Trono D., Verma I.M. and Gage F.H. (1997). Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector. J. Virol. 71, 6641-6649.
-
(1997)
J. Virol.
, vol.71
, pp. 6641-6649
-
-
Blömer, U.1
Naldini, L.2
Kafri, T.3
Trono, D.4
Verma, I.M.5
Gage, F.H.6
-
13
-
-
64449085359
-
A highly reproducible rotenone model of Parkinson's disease
-
Cannon J.R., Tapias V., Na H.M., Honick A.S., Drolet R.E., Greenamyre J.T. (2009). A highly reproducible rotenone model of Parkinson's disease. Neurobiol. Dis. 34, 279-290.
-
(2009)
Neurobiol. Dis.
, vol.34
, pp. 279-290
-
-
Cannon, J.R.1
Tapias, V.2
Na, H.M.3
Honick, A.S.4
Drolet, R.E.5
Greenamyre, J.T.6
-
14
-
-
50549091192
-
Melatonin attenuates tyrosine hydroxylase loss and hypolocomotion in MPTP-lesioned rats
-
Capitelli C., Sereniki A., Lima M.M., Reksidler A.B., Tufik S. and Vital M.A. (2008). Melatonin attenuates tyrosine hydroxylase loss and hypolocomotion in MPTP-lesioned rats. Eur. J. Pharmacol. 594, 101-108.
-
(2008)
Eur. J. Pharmacol.
, vol.594
, pp. 101-108
-
-
Capitelli, C.1
Sereniki, A.2
Lima, M.M.3
Reksidler, A.B.4
Tufik, S.5
Vital, M.A.6
-
15
-
-
77956232379
-
Rasagiline protects against alpha-synuclein induced sensitivity to oxidative stress in dopaminergic cells
-
Chau K.Y., Cooper J.M. and Schapira A.H. (2010). Rasagiline protects against alpha-synuclein induced sensitivity to oxidative stress in dopaminergic cells. Neurochem. Int. 57, 525-529.
-
(2010)
Neurochem. Int.
, vol.57
, pp. 525-529
-
-
Chau, K.Y.1
Cooper, J.M.2
Schapira, A.H.3
-
16
-
-
0027686249
-
Oxidative stress, glutamate, and neurodegenerative disorders
-
Coyle J.T. and Puttfarcken P. (1993). Oxidative stress, glutamate, and neurodegenerative disorders. Science 262, 689-695.
-
(1993)
Science
, vol.262
, pp. 689-695
-
-
Coyle, J.T.1
Puttfarcken, P.2
-
17
-
-
0032816549
-
The substantia nigra of the human brain. II. Patterns of loss of dopaminecontaining neurons in Parkinson's disease
-
Damier P., Hirsch E.C., Agid Y. and Graybiel A.M. (1999). The substantia nigra of the human brain. II. Patterns of loss of dopaminecontaining neurons in Parkinson's disease. Brain 122, 1437-1448.
-
(1999)
Brain
, vol.122
, pp. 1437-1448
-
-
Damier, P.1
Hirsch, E.C.2
Agid, Y.3
Graybiel, A.M.4
-
18
-
-
0037195109
-
Resistance of alpha-synuclein null mice to the parkinsonian neurotoxin MPTP
-
Dauer W., Kholodilov N., Vila M., Trillat A.C., Goodchild R., Larsen K.E., Staal R., Tieu K., Schmitz Y., Yuan C.A., Rocha M., Jackson-Lewis V., Hersch S., Sulzer D., Przedborski S., Burke R. and Hen R. (2002). Resistance of alpha-synuclein null mice to the parkinsonian neurotoxin MPTP. Proc. Natl. Acad. Sci. USA 99, 14524-14529.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 14524-14529
-
-
Dauer, W.1
Kholodilov, N.2
Vila, M.3
Trillat, A.C.4
Goodchild, R.5
Larsen, K.E.6
Staal, R.7
Tieu, K.8
Schmitz, Y.9
Yuan, C.A.10
Rocha, M.11
Jackson-Lewis, V.12
Hersch, S.13
Sulzer, D.14
Przedborski, S.15
Burke, R.16
Hen, R.17
-
19
-
-
0033977265
-
Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease
-
Déglon N., Tseng J.L., Bensadoun J.C., Zurn A.D., Arsenijevic Y., Pereira de Almeida L., Zufferey R., Trono D. and Aebischer P. (2000). Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease. Hum. Gene Ther. 11, 179-190.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 179-190
-
-
Déglon, N.1
Tseng, J.L.2
Bensadoun, J.C.3
Zurn, A.D.4
Arsenijevic, Y.5
Pereira de Almeida, L.6
Zufferey, R.7
Trono, D.8
Aebischer, P.9
-
20
-
-
15744391811
-
Peroxynitrite in the pathogenesis of Parkinson's disease and the neuroprotective role of metallothioneins
-
Ebadi M., Sharma S.K., Ghafourifar P., Brown-Borg H. and El Refaey H. (2005). Peroxynitrite in the pathogenesis of Parkinson's disease and the neuroprotective role of metallothioneins. Methods Enzymol. 396, 276-298.
-
(2005)
Methods Enzymol.
, vol.396
, pp. 276-298
-
-
Ebadi, M.1
Sharma, S.K.2
Ghafourifar, P.3
Brown-Borg, H.4
El Refaey, H.5
-
21
-
-
78549282095
-
Antiinflammatory activity of melatonin in central nervous system
-
Esposito E. and Cuzzocrea S. (2010). Antiinflammatory activity of melatonin in central nervous system. Curr. Neuropharmacol. 8, 228-242.
-
(2010)
Curr. Neuropharmacol.
, vol.8
, pp. 228-242
-
-
Esposito, E.1
Cuzzocrea, S.2
-
22
-
-
0034040751
-
Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
-
Follenzi A., Ailles L.E., Bakovic S., Geuna M. and Naldini L. (2000). Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences. Nat. Genet. 25, 217-222.
-
(2000)
Nat. Genet.
, vol.25
, pp. 217-222
-
-
Follenzi, A.1
Ailles, L.E.2
Bakovic, S.3
Geuna, M.4
Naldini, L.5
-
23
-
-
0030877835
-
Dopamine transporter is required for in vivo MPTP neurotoxicity: Evidence from mice lacking the transporter
-
Gainetdinov R.R., Fumagalli F., Jones S.R. and Caron M.G. (1997). Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter. J. Neurochem. 69, 1322-1325.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1322-1325
-
-
Gainetdinov, R.R.1
Fumagalli, F.2
Jones, S.R.3
Caron, M.G.4
-
24
-
-
79960380554
-
Melatonin as a natural ally against oxidative stress: A physicochemical examination
-
Galano A., Tan D.X. and Reiter R.J. (2011). Melatonin as a natural ally against oxidative stress: a physicochemical examination. J. Pineal Res. 51, 1-16.
-
(2011)
J. Pineal Res.
, vol.51
, pp. 1-16
-
-
Galano, A.1
Tan, D.X.2
Reiter, R.J.3
-
25
-
-
0024434128
-
Midbrain dopaminergic cell loss in Parkinson's disease: Computer visualization
-
German D.C., Manaye K., Smith W.K., Woodward D.J. and Saper C.B. (1989). Midbrain dopaminergic cell loss in Parkinson's disease: computer visualization. Ann. Neurol. 26, 507-514.
-
(1989)
Ann. Neurol.
, vol.26
, pp. 507-514
-
-
German, D.C.1
Manaye, K.2
Smith, W.K.3
Woodward, D.J.4
Saper, C.B.5
-
26
-
-
10744221260
-
Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation
-
Gispert S., Del Turco D., Garrett L., Chen A., Bernard D.J., Hamm-Clement J., Korf H.W., Deller T., Braak H., Auburger G. and Nussbaum R.L. (2003). Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation. Mol. Cell. Neurosci. 24, 419-429.
-
(2003)
Mol. Cell. Neurosci.
, vol.24
, pp. 419-429
-
-
Gispert, S.1
Del Turco, D.2
Garrett, L.3
Chen, A.4
Bernard, D.J.5
Hamm-Clement, J.6
Korf, H.W.7
Deller, T.8
Braak, H.9
Auburger, G.10
Nussbaum, R.L.11
-
27
-
-
77952303591
-
Phenotype, compartmental organization and differential vulnerability of nigral dopaminergic neurons
-
González-Hernández T., Afonso-Oramas D. and Cruz-Muros I. (2009). Phenotype, compartmental organization and differential vulnerability of nigral dopaminergic neurons. J. Neural Transm. Suppl. 73: 21-37.
-
(2009)
J. Neural Transm. Suppl.
, vol.73
, pp. 21-37
-
-
González-Hernández, T.1
Afonso-Oramas, D.2
Cruz-Muros, I.3
-
28
-
-
0141702110
-
Neuroprotective role of melatonin in oxidative stress vulnerable brain
-
Gupta Y.K., Gupta M. and Kohli K. (2003). Neuroprotective role of melatonin in oxidative stress vulnerable brain. Indian J. Physiol. Pharmacol. 47, 373-386.
-
(2003)
Indian J. Physiol. Pharmacol.
, vol.47
, pp. 373-386
-
-
Gupta, Y.K.1
Gupta, M.2
Kohli, K.3
-
29
-
-
33846921608
-
Melatonin inhibits maneb-induced aggregation of asynuclein in rat pheochromocytoma cells
-
Ishido M. (2007). Melatonin inhibits maneb-induced aggregation of asynuclein in rat pheochromocytoma cells. J. Pineal Res. 42, 125-130.
-
(2007)
J. Pineal Res.
, vol.42
, pp. 125-130
-
-
Ishido, M.1
-
30
-
-
0031839674
-
Effect of melatonin on methamphetamine-and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity and methamphetamine-induced behavioral sensitization
-
Itzhak Y., Martin J.L., Black M.D. and Ali S.F. (1998). Effect of melatonin on methamphetamine-and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity and methamphetamine-induced behavioral sensitization. Neuropharmacology 37, 781-791.
-
(1998)
Neuropharmacology
, vol.37
, pp. 781-791
-
-
Itzhak, Y.1
Martin, J.L.2
Black, M.D.3
Ali, S.F.4
-
31
-
-
0026514643
-
What process causes nigral cell death in Parkinson's disease
-
Jenner P. (1992). What process causes nigral cell death in Parkinson's disease? Neurol. Clin. 10, 387-403.
-
(1992)
Neurol. Clin.
, vol.10
, pp. 387-403
-
-
Jenner, P.1
-
32
-
-
34548523836
-
2-and Sin-1-induced cell death
-
2-and Sin-1-induced cell death. Neurobiol. Aging 28, 1709-1717.
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 1709-1717
-
-
Jiang, H.1
Wu, Y.C.2
Nakamura, M.3
Liang, Y.4
Tanaka, Y.5
Holmes, S.6
Dawson, V.L.7
Dawson, T.M.8
Ross, C.A.9
Smith, W.W.10
-
33
-
-
0037040491
-
Human alpha-synuclein overexpression increases intracellular reactive oxygen species levels and susceptibility to dopamine
-
Junn E. and Mouradian M.M. (2002). Human alpha-synuclein overexpression increases intracellular reactive oxygen species levels and susceptibility to dopamine. Neurosci. Lett. 320, 146-150.
-
(2002)
Neurosci. Lett.
, vol.320
, pp. 146-150
-
-
Junn, E.1
Mouradian, M.M.2
-
34
-
-
0036550101
-
Parkinson-like neurodegeneration induced by targeted overexpression of alphasynuclein in the nigrostriatal system
-
Kirik D., Rosenblad C., Burger C., Lundberg C., Johansen T.E., Muzyczka N., Mandel R.J. and Björklund A. (2002). Parkinson-like neurodegeneration induced by targeted overexpression of alphasynuclein in the nigrostriatal system. J. Neurosci. 22, 2780-2791.
-
(2002)
J. Neurosci.
, vol.22
, pp. 2780-2791
-
-
Kirik, D.1
Rosenblad, C.2
Burger, C.3
Lundberg, C.4
Johansen, T.E.5
Muzyczka, N.6
Mandel, R.J.7
Björklund, A.8
-
35
-
-
0345269757
-
Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: A new primate model of Parkinson's disease
-
Kirik D., Annett L.E., Burger C., Muzyczka N., Mandel R.J. and Björklund A. (2003). Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease. Proc. Natl. Acad. Sci. USA 100, 2884-2889.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2884-2889
-
-
Kirik, D.1
Annett, L.E.2
Burger, C.3
Muzyczka, N.4
Mandel, R.J.5
Björklund, A.6
-
36
-
-
0036202813
-
Dopaminergic cell loss induced by human A30P alpha-synuclein gene transfer to the rat substantia nigra
-
Klein R.L., King M.A., Hamby M.E. and Meyer E.M. (2002). Dopaminergic cell loss induced by human A30P alpha-synuclein gene transfer to the rat substantia nigra. Hum. Gene Ther. 13, 605-612.
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 605-612
-
-
Klein, R.L.1
King, M.A.2
Hamby, M.E.3
Meyer, E.M.4
-
38
-
-
43049165779
-
Melatonin inhibits amphetamine-induced increase in alpha-synuclein and decrease in phosphorylated tyrosine hydroxylase in SK-N-SH cells
-
Klongpanichapak S., Phansuwan-Pujito P., Ebadi M. and Govitrapong P. (2008). Melatonin inhibits amphetamine-induced increase in alpha-synuclein and decrease in phosphorylated tyrosine hydroxylase in SK-N-SH cells. Neurosci. Lett. 436, 309-313.
-
(2008)
Neurosci. Lett.
, vol.436
, pp. 309-313
-
-
Klongpanichapak, S.1
Phansuwan-Pujito, P.2
Ebadi, M.3
Govitrapong, P.4
-
39
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger R., Kuhn W., Muller T., Woitalla D., Graeber M., Kösel S., Przuntek H., Epplen J.T., Schöls L. and Riess O. (1998). Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat. Genet. 18, 106-108.
-
(1998)
Nat. Genet.
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kösel, S.6
Przuntek, H.7
Epplen, J.T.8
Schöls, L.9
Riess, O.10
-
40
-
-
0032497504
-
Parkinson's disease. First of two parts
-
Lang A.E. and Lozano A.M. (1998). Parkinson's disease. First of two parts. N. Engl. J. Med. 339, 1044-1053.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1044-1053
-
-
Lang, A.E.1
Lozano, A.M.2
-
41
-
-
0041625923
-
Neuropathology and neurodegeneration in rodent brain induced by lentiviral vector-mediated overexpression of alpha-synuclein
-
Lauwers E., Debyser Z., Van Dorpe J., De Strooper B., Nuttin B. and Baekelandt V. (2003). Neuropathology and neurodegeneration in rodent brain induced by lentiviral vector-mediated overexpression of alpha-synuclein. Brain. Pathol. 13, 364-372.
-
(2003)
Brain. Pathol.
, vol.13
, pp. 364-372
-
-
Lauwers, E.1
Debyser, Z.2
van Dorpe, J.3
de Strooper, B.4
Nuttin, B.5
Baekelandt, V.6
-
42
-
-
33845482072
-
Non-invasive imaging of neuropathology in a rat model of alpha-synuclein overexpression
-
Lauwers E., Bequé D., Van Laere K., Nuyts J., Bormans G., Mortelmans L., Casteels C., Vercammen L., Bockstael O., Nuttin B., Debyser Z. and Baekelandt V. (2007). Non-invasive imaging of neuropathology in a rat model of alpha-synuclein overexpression. Neurobiol. Aging 28, 248-257.
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 248-257
-
-
Lauwers, E.1
Bequé, D.2
van Laere, K.3
Nuyts, J.4
Bormans, G.5
Mortelmans, L.6
Casteels, C.7
Vercammen, L.8
Bockstael, O.9
Nuttin, B.10
Debyser, Z.11
Baekelandt, V.12
-
43
-
-
34447558382
-
Melatonin attenuates arsenite-induced apoptosis in rat brain: Involvement of mitochondrial and endoplasmic reticulum pathways and aggregation of alpha-synuclein
-
Lin A.M., Fang S.F., Chao P.L. and Yang C.H. (2007). Melatonin attenuates arsenite-induced apoptosis in rat brain: involvement of mitochondrial and endoplasmic reticulum pathways and aggregation of alpha-synuclein. J. Pineal Res. 43, 163-171.
-
(2007)
J. Pineal Res.
, vol.43
, pp. 163-171
-
-
Lin, A.M.1
Fang, S.F.2
Chao, P.L.3
Yang, C.H.4
-
44
-
-
39149122800
-
Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-induced parkinsonian rats
-
Lin C.H., Huang J.Y., Ching C.H. and Chuang J.I. (2008). Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-induced parkinsonian rats. J. Pineal Res. 44, 205-213.
-
(2008)
J. Pineal Res.
, vol.44
, pp. 205-213
-
-
Lin, C.H.1
Huang, J.Y.2
Ching, C.H.3
Chuang, J.I.4
-
45
-
-
0036679197
-
(alpha)-synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease
-
Lo Bianco C., Ridet J.L., Schneider B.L., Deglon N. and Aebischer P. (2002). (alpha)-synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease. Proc. Natl. Acad. Sci. USA 99, 10813-10818.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10813-10818
-
-
Lo Bianco, C.1
Ridet, J.L.2
Schneider, B.L.3
Deglon, N.4
Aebischer, P.5
-
46
-
-
10644281090
-
Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease
-
Lo Bianco C., Schneider B.L., Bauer M., Sajadi A., Brice A., Iwatsubo T. and Aebischer P. (2004). Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease. Proc. Natl. Acad. Sci. USA 101, 17510-17515.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 17510-17515
-
-
Lo Bianco, C.1
Schneider, B.L.2
Bauer, M.3
Sajadi, A.4
Brice, A.5
Iwatsubo, T.6
Aebischer, P.7
-
47
-
-
0022447043
-
Prevention of the nigrostriatal toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by inhibitors of 3,4-dihydroxyphenylethylamine transport
-
Mayer R.A., Kindt M.V. and Heikkila R.E. (1986). Prevention of the nigrostriatal toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by inhibitors of 3,4-dihydroxyphenylethylamine transport. J. Neurochem. 47, 1073-1079.
-
(1986)
J. Neurochem.
, vol.47
, pp. 1073-1079
-
-
Mayer, R.A.1
Kindt, M.V.2
Heikkila, R.E.3
-
49
-
-
0035824271
-
Chronic administration of pharmacological levels of melatonin does not ameliorate the MPTPinduced degeneration of the nigrostriatal pathway
-
Morgan W.W. and Nelson J.F. (2001). Chronic administration of pharmacological levels of melatonin does not ameliorate the MPTPinduced degeneration of the nigrostriatal pathway. Brain. Res. 921, 115-121.
-
(2001)
Brain. Res.
, vol.921
, pp. 115-121
-
-
Morgan, W.W.1
Nelson, J.F.2
-
50
-
-
38949146348
-
Mitochondrial dysfunction and oxidative stress in Parkinson's disease
-
Onyango I.G. (2008). Mitochondrial dysfunction and oxidative stress in Parkinson's disease. Neurochem. Res. 33, 589-597.
-
(2008)
Neurochem. Res.
, vol.33
, pp. 589-597
-
-
Onyango, I.G.1
-
51
-
-
0029385216
-
Melatonin stimulates the activity of the detoxifying enzyme glutathione peroxidase in several tissues of chicks
-
Pablos M.I., Agapito M.T., Gutierrez R., Recio J.M., Reiter R.J., Barlow-Walden L., Acuña-Castroviejo D. and Menendez-Pelaez A. (1995). Melatonin stimulates the activity of the detoxifying enzyme glutathione peroxidase in several tissues of chicks. J. Pineal Res. 19, 111-115.
-
(1995)
J. Pineal Res.
, vol.19
, pp. 111-115
-
-
Pablos, M.I.1
Agapito, M.T.2
Gutierrez, R.3
Recio, J.M.4
Reiter, R.J.5
Barlow-Walden, L.6
Acuña-Castroviejo, D.7
Menendez-Pelaez, A.8
-
52
-
-
68949151944
-
Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells
-
Parihar M.S., Parihar A., Fujita M., Hashimoto M. and Ghafourifar P. (2009). Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells. Int. J. Biochem. Cell. Biol. 41, 2015-2024.
-
(2009)
Int. J. Biochem. Cell. Biol.
, vol.41
, pp. 2015-2024
-
-
Parihar, M.S.1
Parihar, A.2
Fujita, M.3
Hashimoto, M.4
Ghafourifar, P.5
-
53
-
-
0037137702
-
Parkin protects against the toxicity associated with mutant alphasynuclein: Proteasome dysfunction selectively affects catecholaminergic neurons
-
Petrucelli L., O'Farrell C., Lockhart P.J., Baptista M., Kehoe K., Vink L., Choi P., Wolozin B., Farrer M., Hardy J. and Cookson M.R. (2002). Parkin protects against the toxicity associated with mutant alphasynuclein: proteasome dysfunction selectively affects catecholaminergic neurons. Neuron 36, 1007-1019.
-
(2002)
Neuron
, vol.36
, pp. 1007-1019
-
-
Petrucelli, L.1
O'Farrell, C.2
Lockhart, P.J.3
Baptista, M.4
Kehoe, K.5
Vink, L.6
Choi, P.7
Wolozin, B.8
Farrer, M.9
Hardy, J.10
Cookson, M.R.11
-
54
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos M.H., Lavedan C., Leroy E., Ide S.E., Dehejia A., Dutra A., Pike B., Root H., Rubenstein J., Boyer R., Stenroos E.S., Chandrasekharappa S., Athanassiadou A., Papapetropoulos T., Johnson W.G., Lazzarini A.M., Duvoisin R.C., Di Iorio G., Golbe L.I. and Nussbaum R.L. (1997). Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276, 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
55
-
-
41149131090
-
Differential effects of overexpression of wild-type and mutant human alpha-synuclein on MPP+-induced neurotoxicity in PC12 cells
-
Qian J.J., Cheng Y.B., Yang Y.P., Mao C.J., Qin Z.H., Li K. and Liu C.F. (2008). Differential effects of overexpression of wild-type and mutant human alpha-synuclein on MPP+-induced neurotoxicity in PC12 cells. Neurosci. Lett. 435, 142-146.
-
(2008)
Neurosci. Lett.
, vol.435
, pp. 142-146
-
-
Qian, J.J.1
Cheng, Y.B.2
Yang, Y.P.3
Mao, C.J.4
Qin, Z.H.5
Li, K.6
Liu, C.F.7
-
56
-
-
1642562820
-
Regulation of antioxidant enzymes: A significant role for melatonin
-
Rodriguez C., Mayo J.C., Sainz R.M., Antolín I., Herrera F., Martín V. and Reiter R.J. (2004). Regulation of antioxidant enzymes: a significant role for melatonin. J. Pineal Res. 36, 1-9.
-
(2004)
J. Pineal Res.
, vol.36
, pp. 1-9
-
-
Rodriguez, C.1
Mayo, J.C.2
Sainz, R.M.3
Antolín, I.4
Herrera, F.5
Martín, V.6
Reiter, R.J.7
-
57
-
-
83555174870
-
Melatonin reduces the expression of alpha-synuclein in the dopamine containing neuronal regions of amphetamine-treated postnatal rats
-
Sae-Ung K., Uéda K., Govitrapong P. and Phansuwan-Pujito P. (2012). Melatonin reduces the expression of alpha-synuclein in the dopamine containing neuronal regions of amphetamine-treated postnatal rats. J. Pineal Res. 52, 128-137.
-
(2012)
J. Pineal Res.
, vol.52
, pp. 128-137
-
-
Sae-Ung, K.1
Uéda, K.2
Govitrapong, P.3
Phansuwan-Pujito, P.4
-
58
-
-
33744982893
-
Etiology of Parkinson's disease
-
Schapira A.H. (2006). Etiology of Parkinson's disease. Neurology 66, S10-S23.
-
(2006)
Neurology
, vol.66
-
-
Schapira, A.H.1
-
59
-
-
0030175258
-
Unilateral 6-hydroxydopamine lesions of meso-striatal dopamine neurons and their physiological sequelae
-
Schwarting R.K. and Huston J.P. (1996). Unilateral 6-hydroxydopamine lesions of meso-striatal dopamine neurons and their physiological sequelae. Prog. Neurobiol. 49, 215-266.
-
(1996)
Prog. Neurobiol.
, vol.49
, pp. 215-266
-
-
Schwarting, R.K.1
Huston, J.P.2
-
60
-
-
31344477300
-
Physiological neuroprotection by melatonin in a 6-hydroxydopamine model of Parkinson's disease
-
Sharma R., McMillan C.R., Tenn C.C. and Niles L.P. (2006). Physiological neuroprotection by melatonin in a 6-hydroxydopamine model of Parkinson's disease. Brain Res. 1068, 230-236.
-
(2006)
Brain Res.
, vol.1068
, pp. 230-236
-
-
Sharma, R.1
McMillan, C.R.2
Tenn, C.C.3
Niles, L.P.4
-
61
-
-
0037104723
-
An in vitro model of Parkinson's disease: Linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage
-
Sherer T.B., Betarbet R., Stout A.K., Lund S., Baptista M., Panov A.V., Cookson M.R. and Greenamyre J.T. (2002). An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage. J. Neurosci. 22, 7006-7015.
-
(2002)
J. Neurosci.
, vol.22
, pp. 7006-7015
-
-
Sherer, T.B.1
Betarbet, R.2
Stout, A.K.3
Lund, S.4
Baptista, M.5
Panov, A.V.6
Cookson, M.R.7
Greenamyre, J.T.8
-
62
-
-
79951634450
-
Melatonin or silymarin reduces maneb-and paraquatinduced Parkinson's disease phenotype in the mouse
-
Singhal N.K., Srivastava G., Patel D.K., Jain S.K. and Singh M.P. (2011). Melatonin or silymarin reduces maneb-and paraquatinduced Parkinson's disease phenotype in the mouse. J. Pineal Res. 50, 97-109.
-
(2011)
J. Pineal Res.
, vol.50
, pp. 97-109
-
-
Singhal, N.K.1
Srivastava, G.2
Patel, D.K.3
Jain, S.K.4
Singh, M.P.5
-
63
-
-
84856721686
-
Melatonin as a neuroprotective agent in the rodent models of Parkinson's disease: Is it all set to irrefutable clinical translation? Mol
-
Singhal N.K., Srivastava G., Agrawal S., Jain S.K., Singh M.P. (2012). Melatonin as a neuroprotective agent in the rodent models of Parkinson's disease: is it all set to irrefutable clinical translation? Mol. Neurobiol. 45, 186-199.
-
(2012)
Neurobiol.
, vol.45
, pp. 186-199
-
-
Singhal, N.K.1
Srivastava, G.2
Agrawal, S.3
Jain, S.K.4
Singh, M.P.5
-
65
-
-
27744510015
-
Role of melatonin in neurodegenerative diseases
-
Srinivasan V., Pandi-Perumal S.R., Maestroni G.J., Esquifino A.I., Hardeland R. and Cardinali D.P. (2005). Role of melatonin in neurodegenerative diseases. Neurotox. Res. 7, 293-318.
-
(2005)
Neurotox. Res.
, vol.7
, pp. 293-318
-
-
Srinivasan, V.1
Pandi-Perumal, S.R.2
Maestroni, G.J.3
Esquifino, A.I.4
Hardeland, R.5
Cardinali, D.P.6
-
66
-
-
74049134972
-
Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model
-
Tapias V., Cannon J.R. and Greenamyre J.T. (2010). Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model. J. Neurosci. Res. 88, 420-427.
-
(2010)
J. Neurosci. Res.
, vol.88
, pp. 420-427
-
-
Tapias, V.1
Cannon, J.R.2
Greenamyre, J.T.3
-
67
-
-
5444255433
-
Neurotoxicant-induced animal models of Parkinson's disease: Understanding the role of rotenone, maneb and paraquat in neurodegeneration
-
Uversky V.N. (2004). Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration. Cell. Tissue Res. 318, 225-241.
-
(2004)
Cell. Tissue Res.
, vol.318
, pp. 225-241
-
-
Uversky, V.N.1
-
68
-
-
0000785747
-
Melatonin fails to protect against long-term MPTP-induced dopamine depletion in mouse striatum
-
van der Schyf C.J., Castagnoli K., Palmer S., Hazelwood L. and Castagnoli N. Jr (2000). Melatonin fails to protect against long-term MPTP-induced dopamine depletion in mouse striatum. Neurotox. Res. 1, 261-269.
-
(2000)
Neurotox. Res.
, vol.1
, pp. 261-269
-
-
van der Schyf, C.J.1
Castagnoli, K.2
Palmer, S.3
Hazelwood, L.4
Castagnoli Jr., N.5
-
69
-
-
0037448010
-
2in a human neuroblastoma divided cell line transfected with alpha-synuclein and its familial Parkinson's disease-linked mutants
-
2in a human neuroblastoma divided cell line transfected with alpha-synuclein and its familial Parkinson's disease-linked mutants. Neurosci. Lett. 342, 124-128.
-
(2003)
Neurosci. Lett.
, vol.342
, pp. 124-128
-
-
Wersinger, C.1
Sidhu, A.2
-
70
-
-
10744230149
-
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia
-
Zarranz J.J., Alegre J., Gomez-Esteban J.C., Lezcano E., Ros R., Ampuero I., Vidal L., Hoenicka J., Rodriguez O., Atarés B., Llorens V., Gomez Tortosa E., del Ser T., Muñoz D.G. and de Yebenes JG. (2004). The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. Ann. Neurol. 55, 164-173.
-
(2004)
Ann. Neurol.
, vol.55
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
Vidal, L.7
Hoenicka, J.8
Rodriguez, O.9
Atarés, B.10
Llorens, V.11
Gomez Tortosa, E.12
del Ser, T.13
Muñoz, D.G.14
de Yebenes, J.G.15
-
71
-
-
0034646513
-
HIV-1 genome nuclear import is mediated by a central DNA flap
-
Zennou V., Petit C., Guetard D., Nerhbass U., Montagnier L. and Charneau P. (2000). HIV-1 genome nuclear import is mediated by a central DNA flap. Cell 101, 173-185.
-
(2000)
Cell
, vol.101
, pp. 173-185
-
-
Zennou, V.1
Petit, C.2
Guetard, D.3
Nerhbass, U.4
Montagnier, L.5
Charneau, P.6
-
72
-
-
0035562519
-
Melatonin-dopamine interactions: From basic neurochemistry to a clinical setting
-
Zisapel N. (2001). Melatonin-dopamine interactions: from basic neurochemistry to a clinical setting. Cell. Mol. Neurobiol. 21, 605-616.
-
(2001)
Cell. Mol. Neurobiol.
, vol.21
, pp. 605-616
-
-
Zisapel, N.1
-
73
-
-
0031743608
-
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
-
Zufferey R., Dull T., Mandel R.J., Bukovsky A., Quiroz D., Naldini L. and Trono D. (1998). Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J. Virol. 72, 9873-9880.
-
(1998)
J. Virol.
, vol.72
, pp. 9873-9880
-
-
Zufferey, R.1
Dull, T.2
Mandel, R.J.3
Bukovsky, A.4
Quiroz, D.5
Naldini, L.6
Trono, D.7
-
74
-
-
0030819379
-
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
-
Zufferey R., Nagy D., Mandel R.J., Naldini L. and Trono D. (1997). Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat. Biotech. 15, 871-875.
-
(1997)
Nat. Biotech.
, vol.15
, pp. 871-875
-
-
Zufferey, R.1
Nagy, D.2
Mandel, R.J.3
Naldini, L.4
Trono, D.5
-
75
-
-
0032978712
-
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
-
Zufferey R., Donello J.E., Trono D. and Hope T.J. (1999). Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J. Virol. 73, 2886-2892.
-
(1999)
J. Virol.
, vol.73
, pp. 2886-2892
-
-
Zufferey, R.1
Donello, J.E.2
Trono, D.3
Hope, T.J.4
|