Genoprotection and genotoxicity of green tea (Camellia sinensis): Are they two sides of the same redox coin?

Redox Report

Volumn 18, Issue 4, 2013, Pages 150-154

  Ho, Cyrus K ^a   Siu Wai, Choi ^a   Siu, Parco M ^a   Benzie, Iris F ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

ARE; DNA damage; Genoprotection; Green tea; HO 1; Hydrogen peroxide; Oxidative stress; Pro oxidant; Redox tone

Indexed keywords

CATALASE; CATECHIN; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; HEME OXYGENASE 1; HYDROGEN PEROXIDE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; PHOSPHATE BUFFERED SALINE; POLYPHENOL; TRANSCRIPTION FACTOR NRF2;

ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; AUTOOXIDATION; COLORIMETRY; COMET ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; GENE EXPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TEMPERATURE; INCUBATION TIME; NORMAL HUMAN; OXIDATION REDUCTION STATE; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TEA;

ANTIOXIDANT RESPONSE ELEMENTS; ANTIOXIDANTS; CAMELLIA SINENSIS; CATALASE; DNA DAMAGE; HEALTHY VOLUNTEERS; HUMANS; HYDROGEN PEROXIDE; LYMPHOCYTES; OXIDANTS; OXIDATION-REDUCTION; TEA;

EID: 84880395062     PISSN: 13510002     EISSN: 17432928     Source Type: Journal    
DOI: 10.1179/1351000213Y.0000000051     Document Type: Article

References (32)

1. Huo C, Wan SB, Lam WH, Li L, Wang Z, Landis-Piwowar KR, et al. The challenge of developing green tea polyphenols as therapeutic agents. Inflammopharmacology 2008;16:248-52.
2. Serafini M, Miglio C, Peluso I, Petrosino T. Modulation of plasma non enzymatic antioxidant capacity (NEAC) by plant foods: the role of polyphenols. Curr Top Med Chem 2011; 11(14):1821-46.
3. Wang ZM, Zhou B, Wang YS, Gong QY, Wang QM, Yan JJ, et al. Black and green tea consumption and the risk of coronary artery disease: a meta-analysis. Am J Clin Nutr 2011;93(3):506-15.
4. Del Rio D, Calani L, Scazzina F, Jechiu L, Cordero C, Brighenti F. Bioavailability of catechins from ready-to-drink tea. J Nutr 2010;26:528-33.
5. Benzie IFF, Szeto YT, Strain JJ, Tomlinson B. Consumption of green tea causes rapid increase in plasma antioxidant power in humans. Nutr Cancer 1999;34(1):83-7.
6. Fung TS, Ho CK, Choi SW, Chung WY, Benzie IFF. Comparison of catechin profiles in human plasma and urine after single dosing and regular intake of green tea (Camellia sinensis). Br J Nutr 2012;30:1-9.
7. Han KC, Wong WC, Benzie IFF. Genoprotective effects of green tea (Camellia sinensis) in human subjects: results of a controlled supplementation trial. Br J Nutr 2011;1:1-8.
8. Kanadzu M, Lu YQ, Morimoto K. Dual function of (-)-epigallocatechin gallate (ECGC) in healthy human lymphocytes. Cancer Lett 2006;241:250-5.
9. Halliwell B, Gutteridge JMC. Free radicals in biology and medicine. USA: Oxford University Press; 2007.
10. Galati G, Lin A, Sultan AM, O'Brien PJ. Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins. Free Radic Biol Med 2006;40(4):570-80.
11. Lambert JD, Kennett MJ, Sang S, Reuhl KR, Ju J, Yang CS. Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice. Food Chem Toxicol 2010;48(1):409-16.
12. Martin KR, Appel CL. Polyphenols as dietary supplements: a double-edged sword. Nutr Diet Suppl 2010;2:1-12.
13. Inoue H, Akiyama S, Maeda-Tamamoto M, Nesumi A, Tanaka T, Murakami A. High-dose green tea polyphenols induce nephrotoxicity in dextran sulfate sodium-induced colitis mice by down-regulation of antioxidant enzymes and heat-shock protein expressions. Cell Stress Chaperones 2011;16(6):653-62.
14. Soares MP, Bach FH. Heme oxygenase-1: from biology to therapeutic potential. Trends Mol Med 2008;15(2):50-8.
15. Surh YJ, Kundu JK, Na HK. Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotection genes by some chemopreventive phytochemicals. Planta Med 2008;74:1526-39.
16. Benzie IFF, Wachtel-Galor S. Vegetarian diets and public health: biomarker and redox connections. Antiox Redox Signal 2010;13: 1575-91.
17. Ho CK, Choi SW, Siu PM, Benzie IFF. Cryopreservation and storage effects on cell number s and DNA damage in human lymphocytes. Biopreserv Biobank 2011;9(4):343-7.
18. Collins AR, Oscoz AA, Brunborg G, Gaivão I, Giovannelli L, Kruszewski M, et al. The comet assay: topical issues. Mutagenesis 2008;23(3):143-51.
19. Røge R, Thorsen J, Tørring C, Ozbay A, Møller BK, Carstens J. Commonly used reference genes are actively regulated in in vitro stimulated lymphocytes. Scand J Immunol 2007;65(2):202-9.
20. Jiang ZY, Hun JV, Wolff SP. Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low density lipoprotein. Anal Biochem 1992;202(2):2099-117.
21. Yuen JW, Benzie IFF. Hydrogen peroxide in urine as a potential biomarker of whole body oxidative stress. Free Radic Res 2003; 37(11):1209-13.
22. Pfaffl MW, Horgan GW, Dempfle L. Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucl Acids Res 2002;30(9):e36.
23. King HC, Shinha AA. Gene expression profile analysis by DNA microarrays: promise and pitfalls. JAMA 2001;286(18):2280-8.
24. Zajchowski DA, Bartholdi MF, Gong Y, Webster L, Liu HL, Munishkin A, et al. Identification of gene expression profiles that predict the aggressive behavior of breast cancer cells. Cancer Res 2001;61(13):5168-78.
25. Tu Y, Stolovitzky G, Klein U. Quantitative noise analysis for gene expression microarray experiments. Proc Natl Acad Sci 2002;99(22):14031-6.
26. Bosio A, Knörr C, Janssen U, Gebel S, Haussmann H, Müller T. Kinetics of gene expression profiling in Swiss 3T3 cells exposed to aqueous extracts of cigarette smoke. Carcinogenesis 2002; 23(5):741-8.
27. Reichard JF, Motz GT, Puga A. Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1. Nucleic Acids Res 2007;35(2):7074-86.
28. Bergström P, Andersson HC, Gao Y, Karlsson JO, Nodin C, Anderson MF, et al. Repeated transient sulforaphane stimulation in astrocytes leads to prolonged Nrf2-mediated gene expression and protection from superoxide-induced damage. Neuropharmacology 2011;60:343-53.
29. Collins AR, Azqueta A. DNA repair as a biomarker in human biomonitoring studies: further applications of the comet assay. Mutat Res 2012;736(1-2):122-9.
30. Koketsu S, Watanabe T, Nagawa H. Expression of DNA repair protein: MYH, NTH1, and MTH1 in colorectal cancer. Hepatogastroenterology 2004;51(57):638-42.
31. Zhang QM, Yonekura S, Takao M, Yasui A, Sugiyama H, Yonei S. DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the hNEIL1 and hNTH1 enzymes in human cells. DNA Repair 2005;4:71-9.
32. Williams RJ, Spencer JPE, Rice-Evans C. Flavonoids: antioxidants or signalling molecules. Free Radic Biol Med 2004;36: 838-49.