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Volumn 1290, Issue 1, 2013, Pages 1-11

What is new for resveratrol? Is a new set of recommendations necessary?

Author keywords

Clinical trials; Human health; Human use; Resveratrol

Indexed keywords

CURCUMIN; GENISTEIN; LONGEVINEX; POLYGONUM CUSPIDATUM EXTRACT; QUERCETIN; RESVERATROL; UNCLASSIFIED DRUG;

EID: 84880392788     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/nyas.12173     Document Type: Article
Times cited : (38)

References (40)
  • 1
    • 59049088773 scopus 로고
    • Resveratrol, a new phenolic compound from Veratrum grandiflorum
    • Takaoka, M. 1939. Resveratrol, a new phenolic compound from Veratrum grandiflorum. Nippon Kagaku Kaichi 60: 1090-1100.
    • (1939) Nippon Kagaku Kaichi , vol.60 , pp. 1090-1100
    • Takaoka, M.1
  • 2
    • 0019940467 scopus 로고
    • Effects of stilbene components of the roots of Polygonum cuspidatum Sieb. et Zucc. on lipid metabolism
    • Arichi, H., Y. Kimura, H. Okuda, et al. 1982. Effects of stilbene components of the roots of Polygonum cuspidatum Sieb. et Zucc. on lipid metabolism. Chem. Pharm. Bull. 30: 1766-1770.
    • (1982) Chem. Pharm. Bull. , vol.30 , pp. 1766-1770
    • Arichi, H.1    Kimura, Y.2    Okuda, H.3
  • 3
    • 0002256765 scopus 로고
    • Concentration of the phytoalexin resveratrol in wine
    • Siemann, E.H. & L.L. Creasy. 1992. Concentration of the phytoalexin resveratrol in wine. Amer. J. Enol. Viticult. 43: 49-52.
    • (1992) Amer. J. Enol. Viticult. , vol.43 , pp. 49-52
    • Siemann, E.H.1    Creasy, L.L.2
  • 4
    • 0027447124 scopus 로고
    • Inhibition of human LDL oxidation by resveratrol
    • Frankel, E.N., A.L. Waterhouse & J.E. Kinsella. 1993. Inhibition of human LDL oxidation by resveratrol. Lancet 341: 1103-1104.
    • (1993) Lancet , vol.341 , pp. 1103-1104
    • Frankel, E.N.1    Waterhouse, A.L.2    Kinsella, J.E.3
  • 5
    • 0031561513 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
    • Jang, M., L. Cai, G.O. Udeani, et al. 1997. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 275: 218-220.
    • (1997) Science , vol.275 , pp. 218-220
    • Jang, M.1    Cai, L.2    Udeani, G.O.3
  • 6
    • 0141719702 scopus 로고    scopus 로고
    • Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
    • Howitz, K.T., K.J. Bitterman, H.Y. Cohen, et al. 2003. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425: 191-196.
    • (2003) Nature , vol.425 , pp. 191-196
    • Howitz, K.T.1    Bitterman, K.J.2    Cohen, H.Y.3
  • 7
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • Baur, J. A., K.J. Pearson, N.L. Price, et al. 2006. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444: 337-342.
    • (2006) Nature , vol.444 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3
  • 8
    • 33845399894 scopus 로고    scopus 로고
    • Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
    • Lagouge, M., C. Argmann, Z. Gerhart-Hines, et al. 2006. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell 127: 1109-1122.
    • (2006) Cell , vol.127 , pp. 1109-1122
    • Lagouge, M.1    Argmann, C.2    Gerhart-Hines, Z.3
  • 9
    • 0018137952 scopus 로고
    • Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles
    • Wattenberg, L.W. & W.D. Loub. 1978. Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles. Cancer Res. 38: 1410-1413.
    • (1978) Cancer Res. , vol.38 , pp. 1410-1413
    • Wattenberg, L.W.1    Loub, W.D.2
  • 10
    • 84873040404 scopus 로고    scopus 로고
    • Resveratrol exerts differential effects in vitro and in vivo against ovarian cancer cells
    • Stakleff, K.S., T. Sloan, D. Blanco, et al. 2012. Resveratrol exerts differential effects in vitro and in vivo against ovarian cancer cells. Asian Pac. J. Cancer Prev. 13: 1333-1340.
    • (2012) Asian Pac. J. Cancer Prev. , vol.13 , pp. 1333-1340
    • Stakleff, K.S.1    Sloan, T.2    Blanco, D.3
  • 11
    • 79959261445 scopus 로고    scopus 로고
    • What is new for an old molecule? Systematic review and recommendations on the use of resveratrol
    • Vang, O., N. Ahmad, C.A. Baile, et al. 2011. What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. PLoS ONE 6: e19881.
    • (2011) PLoS ONE , vol.6
    • Vang, O.1    Ahmad, N.2    Baile, C.A.3
  • 12
    • 68049147267 scopus 로고    scopus 로고
    • Safety studies conducted on high-purity trans-resveratrol in experimental animals
    • Williams, L.D., G.A. Burdock, J.A. Edwards, et al. 2009. Safety studies conducted on high-purity trans-resveratrol in experimental animals. Food Chem. Toxicol. 49: 2170-2182.
    • (2009) Food Chem. Toxicol. , vol.49 , pp. 2170-2182
    • Williams, L.D.1    Burdock, G.A.2    Edwards, J.A.3
  • 13
    • 80052910300 scopus 로고    scopus 로고
    • Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients
    • Brasnyo, P., G.A. Molnar, M. Mohas, et al. 2011. Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients. Br. J. Nutr. 106: 383-389.
    • (2011) Br. J. Nutr. , vol.106 , pp. 383-389
    • Brasnyo, P.1    Molnar, G.A.2    Mohas, M.3
  • 14
    • 84860558348 scopus 로고    scopus 로고
    • Cardioprotection by resveratrol: a human clinical trial in patients with stable coronary artery disease
    • Magyar, K., R. Halmosi, A. Palfi, et al. 2012. Cardioprotection by resveratrol: a human clinical trial in patients with stable coronary artery disease. Clin. Hemorheol. Microcirc. 50: 179-187.
    • (2012) Clin. Hemorheol. Microcirc. , vol.50 , pp. 179-187
    • Magyar, K.1    Halmosi, R.2    Palfi, A.3
  • 15
    • 78549288940 scopus 로고    scopus 로고
    • Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics, and effect on the insulin-like growth factor axis
    • Brown, V.A., K.R. Patel, M. Viskaduraki, et al. 2010. Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics, and effect on the insulin-like growth factor axis. Cancer Res. 70: 9003-9011.
    • (2010) Cancer Res. , vol.70 , pp. 9003-9011
    • Brown, V.A.1    Patel, K.R.2    Viskaduraki, M.3
  • 16
    • 80052572943 scopus 로고    scopus 로고
    • Phase I randomised double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases-safety, pharmacokinetics andpharmacodynamics
    • Howells, L.M., D.P. Berry, P.J. Elliott, et al. 2011. Phase I randomised double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases-safety, pharmacokinetics andpharmacodynamics. Cancer Prev. Res. 4: 1419-1425.
    • (2011) Cancer Prev. Res. , vol.4 , pp. 1419-1425
    • Howells, L.M.1    Berry, D.P.2    Elliott, P.J.3
  • 18
    • 77953032816 scopus 로고    scopus 로고
    • Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation
    • Kennedy, D.O., E.L. Wightman, J.L. Reay, et al. 2010. Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation. Am. J. Clin. Nutr. 91: 1590-1597.
    • (2010) Am. J. Clin. Nutr. , vol.91 , pp. 1590-1597
    • Kennedy, D.O.1    Wightman, E.L.2    Reay, J.L.3
  • 19
    • 84950170835 scopus 로고    scopus 로고
    • Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure
    • Wong, R.H.X., P.R.C. Howe, J.D. Buckley, et al. 2011. Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure. Nutr. Metab. Cardiovasc. Dis. 21: 851-856.
    • (2011) Nutr. Metab. Cardiovasc. Dis. , vol.21 , pp. 851-856
    • Wong, R.H.X.1    Howe, P.R.C.2    Buckley, J.D.3
  • 20
    • 84869129105 scopus 로고    scopus 로고
    • Intake of a resveratrol-containing dietary supplement has no impact on DNA stability in healthy subjects
    • Heger, A., F. Ferk, A. Nersesyan, et al. 2012. Intake of a resveratrol-containing dietary supplement has no impact on DNA stability in healthy subjects. Mutat. Res. 749: 82-86.
    • (2012) Mutat. Res. , vol.749 , pp. 82-86
    • Heger, A.1    Ferk, F.2    Nersesyan, A.3
  • 21
    • 77957355158 scopus 로고    scopus 로고
    • Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients
    • Patel, K.R., V.A. Brown, D.J. Jones, et al. 2010. Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients. Cancer Res. 70: 7392-7399.
    • (2010) Cancer Res. , vol.70 , pp. 7392-7399
    • Patel, K.R.1    Brown, V.A.2    Jones, D.J.3
  • 22
    • 84861697559 scopus 로고    scopus 로고
    • Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: A triple-blind, 6-month follow-up, placebo-controlled, randomized trial
    • Tome-Carneiro, J., M. Gonzalvez, M. Larrosa, et al. 2012. Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: A triple-blind, 6-month follow-up, placebo-controlled, randomized trial. Mol. Nutr. Food Res. 56: 810-821.
    • (2012) Mol. Nutr. Food Res. , vol.56 , pp. 810-821
    • Tome-Carneiro, J.1    Gonzalvez, M.2    Larrosa, M.3
  • 23
    • 80455143206 scopus 로고    scopus 로고
    • Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
    • Timmers, S., E. Konings, L. Bilet, et al. 2011. Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab. 14: 612-622.
    • (2011) Cell Metab. , vol.14 , pp. 612-622
    • Timmers, S.1    Konings, E.2    Bilet, L.3
  • 24
    • 84887211967 scopus 로고    scopus 로고
    • Resveratrol improves glucose metabolism in older adults with IGT [abstract]
    • Crandall, J.P., V. Oram, G. Trandafirescu, et al. 2010. Resveratrol improves glucose metabolism in older adults with IGT [abstract]. Diabetes 59: A201.
    • (2010) Diabetes , vol.59
    • Crandall, J.P.1    Oram, V.2    Trandafirescu, G.3
  • 25
    • 84870851275 scopus 로고    scopus 로고
    • Oral resveratrol and calcium fructoborate supplementation in subjects with stable angina pectoris: effects on lipid profiles, inflammation markers, and quality of life
    • Militaru, C., I. Donoiu, A. Craciun, et al. 2013. Oral resveratrol and calcium fructoborate supplementation in subjects with stable angina pectoris: effects on lipid profiles, inflammation markers, and quality of life. Nutrition 29: 178-183.
    • (2013) Nutrition , vol.29 , pp. 178-183
    • Militaru, C.1    Donoiu, I.2    Craciun, A.3
  • 26
    • 84871445402 scopus 로고    scopus 로고
    • Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance
    • Yoshino, J., C. Conte, L. Fontana, et al. 2012. Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance. Cell Metab. 15: 658-664.
    • (2012) Cell Metab. , vol.15 , pp. 658-664
    • Yoshino, J.1    Conte, C.2    Fontana, L.3
  • 27
    • 84875431034 scopus 로고    scopus 로고
    • High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition
    • DOI: 10.2337/db12-0975.
    • Poulsen, M.M., P.F. Vestergaard, B.F. Clasen, et al. 2013. High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition. Diabetes DOI: 10.2337/db12-0975.
    • (2013) Diabetes
    • Poulsen, M.M.1    Vestergaard, P.F.2    Clasen, B.F.3
  • 28
    • 77956412951 scopus 로고    scopus 로고
    • Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study
    • Chow, H.H., L.L. Garland, C.H. Hsu, et al. 2010. Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study. Cancer Prev. Res. 3: 1168-1175.
    • (2010) Cancer Prev. Res. , vol.3 , pp. 1168-1175
    • Chow, H.H.1    Garland, L.L.2    Hsu, C.H.3
  • 29
    • 79952136521 scopus 로고    scopus 로고
    • Resveratrol-containing gel for the treatment of acne vulgaris: a single-blind, vehicle-controlled, pilot study
    • Fabbrocini, G., S. Staibano, G. De Rosa, et al. 2011. Resveratrol-containing gel for the treatment of acne vulgaris: a single-blind, vehicle-controlled, pilot study. Am. J. Clin. Dermatol. 12: 133-141.
    • (2011) Am. J. Clin. Dermatol. , vol.12 , pp. 133-141
    • Fabbrocini, G.1    Staibano, S.2    De Rosa, G.3
  • 30
    • 79955675928 scopus 로고    scopus 로고
    • A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal
    • Ghanim, H., C.L. Sia, K. Korzeniewski, et al. 2011. A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal. J. Clin. Endocrinol. Metab. 96: 1409-1414.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , pp. 1409-1414
    • Ghanim, H.1    Sia, C.L.2    Korzeniewski, K.3
  • 31
    • 82455220960 scopus 로고    scopus 로고
    • Modified resveratrol Longevinex improves endothelial function in adults with metabolic syndrome receiving standard treatment
    • Fujitaka, K., H. Otani, F. Jo, et al. 2011. Modified resveratrol Longevinex improves endothelial function in adults with metabolic syndrome receiving standard treatment. Nutr. Res. 31: 842-847.
    • (2011) Nutr. Res. , vol.31 , pp. 842-847
    • Fujitaka, K.1    Otani, H.2    Jo, F.3
  • 32
    • 84863980958 scopus 로고    scopus 로고
    • One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease
    • Tome-Carneiro, J., M. Gonzalvez, M. Larrosa, et al. 2012. One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease. Am. J. Cardiol. 110: 356-363.
    • (2012) Am. J. Cardiol. , vol.110 , pp. 356-363
    • Tome-Carneiro, J.1    Gonzalvez, M.2    Larrosa, M.3
  • 33
    • 84872876538 scopus 로고    scopus 로고
    • Resveratrol-procyanidin blend: nutraceutical and antiaging efficacy evaluated in a placebocontrolled, double-blind study
    • Buonocore, D., A. Lazzeretti, P. Tocabens, et al. 2012. Resveratrol-procyanidin blend: nutraceutical and antiaging efficacy evaluated in a placebocontrolled, double-blind study. Clin Cosmet. Investig. Dermatol. 5: 159-165.
    • (2012) Clin Cosmet. Investig. Dermatol. , vol.5 , pp. 159-165
    • Buonocore, D.1    Lazzeretti, A.2    Tocabens, P.3
  • 34
    • 79958099432 scopus 로고    scopus 로고
    • Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer
    • Nguyen, A.V., M. Martinez, M.J. Stamos, et al. 2009. Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer. Cancer Manag. Res. 1: 25-37.
    • (2009) Cancer Manag. Res. , vol.1 , pp. 25-37
    • Nguyen, A.V.1    Martinez, M.2    Stamos, M.J.3
  • 35
    • 84863230448 scopus 로고    scopus 로고
    • Red versus white wine as a nutritional aromatase inhibitor in premenopausal women: a pilot study
    • Shufelt, C., C.N. Merz, Y. Yang, et al. 2012. Red versus white wine as a nutritional aromatase inhibitor in premenopausal women: a pilot study. J. Womens Health (Larchmt.) 21: 281-284.
    • (2012) J. Womens Health (Larchmt.) , vol.21 , pp. 281-284
    • Shufelt, C.1    Merz, C.N.2    Yang, Y.3
  • 36
    • 78049518309 scopus 로고    scopus 로고
    • Dietary grape-derived resveratrol for colon cancer prevention [abstract]
    • Abstr. 3622.
    • Martinez, M., C. Hope, K. Planutis, et al. 2010. Dietary grape-derived resveratrol for colon cancer prevention [abstract]. J. Clin. Oncol. 28, 15S, Abstr. 3622.
    • (2010) J. Clin. Oncol. , vol.28
    • Martinez, M.1    Hope, C.2    Planutis, K.3
  • 37
    • 77956585215 scopus 로고    scopus 로고
    • An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol
    • Ghanim, H., C.L. Sia, S. Abuaysheh, et al. 2010. An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J. Clin. Endocrinol. Metab. 95: E1-E8.
    • (2010) J. Clin. Endocrinol. Metab. , vol.95
    • Ghanim, H.1    Sia, C.L.2    Abuaysheh, S.3
  • 38
    • 77950493668 scopus 로고    scopus 로고
    • An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach
    • Bakker, G.C.M., M.J. van Erk, L. Pellis, et al. 2010. An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach. Am. J. Clin. Nutr. 91: 1044-1059.
    • (2010) Am. J. Clin. Nutr. , vol.91 , pp. 1044-1059
    • Bakker, G.C.M.1    van Erk, M.J.2    Pellis, L.3
  • 39
    • 84863515154 scopus 로고    scopus 로고
    • Effect of the intake of resveratrol, resveratrol phosphate, and catechin-rich grape seed extract on markers of oxidative stress and gene expression in adult obese subjects
    • De Groote, D., K. Van Belleghem, J. Deviere, et al. 2012. Effect of the intake of resveratrol, resveratrol phosphate, and catechin-rich grape seed extract on markers of oxidative stress and gene expression in adult obese subjects. Ann. Nutr. Metab. 61: 15-24.
    • (2012) Ann. Nutr. Metab. , vol.61 , pp. 15-24
    • De Groote, D.1    Van Belleghem, K.2    Deviere, J.3
  • 40
    • 84856384386 scopus 로고    scopus 로고
    • Differential effects of polyphenols and alcohol of red wine on the expression of adhesion molecules and inflammatory cytokines related to atherosclerosis: a randomized clinical trial
    • Chiva-Blanch, G., M. Urpi-Sarda, R. Llorach, et al. 2012. Differential effects of polyphenols and alcohol of red wine on the expression of adhesion molecules and inflammatory cytokines related to atherosclerosis: a randomized clinical trial. Am. J. Clin. Nutr. 95: 326-334.
    • (2012) Am. J. Clin. Nutr. , vol.95 , pp. 326-334
    • Chiva-Blanch, G.1    Urpi-Sarda, M.2    Llorach, R.3


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