DNA cytosine C5 methyltransferase Dnmt1: Catalysis-dependent release of allosteric inhibition

Biochemistry

Volumn 44, Issue 27, 2005, Pages 9472-9485

  Svedruzic, Zeljko M ^a,b   Reich, Norbert O ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CATALYSIS; DNA; ENZYME KINETICS; MUTAGENESIS; ORGANIC SOLVENTS;

CYTOSINE; GUANINE; METHYL TRANSFER; METHYLATION;

ENZYMES;

DNA; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; TRITIUM; BACTERIAL DNA; DNA (CYTOSINE 5 ) METHYLTRANSFERASE 1; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; DNA MODIFICATION METHYLASE HHAI; POLY D(I C); POLY D(I-C); POLY[DEOXY(CYTIDYLATE GUANYLATE)]; POLYDEOXYRIBONUCLEOTIDE; S ADENOSYLMETHIONINE; SITE SPECIFIC DNA METHYLTRANSFERASE (CYTOSINE SPECIFIC);

ALLOSTERISM; ARTICLE; CATALYSIS; DNA BINDING; DNA METHYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ESCHERICHIA COLI; MICHAELIS MENTEN KINETICS; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; DEUTERIUM HYDROGEN EXCHANGE; DRUG ANTAGONISM; ENZYME ACTIVATION; ENZYME SPECIFICITY; ENZYMOLOGY; ERYTHROLEUKEMIA; KINETICS; METABOLISM; MOUSE; SPECTROFLUOROMETRY; TUMOR CELL LINE;

ALLOSTERIC REGULATION; ANIMALS; CATALYSIS; CELL LINE, TUMOR; DEUTERIUM EXCHANGE MEASUREMENT; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA, BACTERIAL; ENZYME ACTIVATION; KINETICS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; MICE; POLYDEOXYRIBONUCLEOTIDES; S-ADENOSYLMETHIONINE; SITE-SPECIFIC DNA METHYLTRANSFERASE (CYTOSINE-SPECIFIC); SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY; TRITIUM;

EID: 21844479555     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050295z     Document Type: Article

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