메뉴 건너뛰기




Volumn 13, Issue , 2013, Pages

Potassium channel openers and prostacyclin play a crucial role in mediating the vasorelaxant activity of Gynura procumbens

Author keywords

Calcium channel; Gynura procumbens; Potassium channel; Prostacylin; Vasodilation

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 4 AMINOPYRIDINE; ATROPINE; BUTANOLIC FRACTION; CAFFEINE; CALCIUM; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; FLAVANOID; GLIBENCLAMIDE; INDOMETACIN; METHYLENE BLUE; N(G) NITROARGININE METHYL ESTER; NORADRENALIN; PHENYLEPHRINE; POTASSIUM; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; POTASSIUM CHLORIDE; PROPANOL; PROSTACYCLIN; SUB FRACTION F1; SUB FRACTION F2; SUB FRACTION F3; SUB FRACTION F4; SUB FRACTION F5; SUB FRACTION F6; SUB FRACTION F7; SUB FRACTION F8; TETRYLAMMONIUM; UNCLASSIFIED DRUG;

EID: 84880335204     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-13-188     Document Type: Article
Times cited : (26)

References (44)
  • 2
    • 27144435569 scopus 로고    scopus 로고
    • International Society of Hypertension (ISH) statement on management of hypertension
    • Norman K, Shanthi M, Neil P, Judith W. International Society of Hypertension (ISH) statement on management of hypertension. J Hypertens 2003, 21:1983-1992.
    • (2003) J Hypertens , vol.21 , pp. 1983-1992
    • Norman, K.1    Shanthi, M.2    Neil, P.3    Judith, W.4
  • 3
    • 84879282831 scopus 로고
    • Hemodynamic and endocrine changes associated with captopril in diuretic resistant patients
    • 10.1016/0002-9343(82)90724-0, 6751080
    • Fusita T, Ando K, Noda H, Sato Y, Yamashita N, Yamashita K. Hemodynamic and endocrine changes associated with captopril in diuretic resistant patients. Am J Med 1982, 73:341-347. 10.1016/0002-9343(82)90724-0, 6751080.
    • (1982) Am J Med , vol.73 , pp. 341-347
    • Fusita, T.1    Ando, K.2    Noda, H.3    Sato, Y.4    Yamashita, N.5    Yamashita, K.6
  • 4
    • 26444560139 scopus 로고
    • Hydralazine in hypertension
    • 10.1016/0002-8703(64)90408-9, 14110653
    • Freis ED. Hydralazine in hypertension. Am Heart J 1964, 67:133-134. 10.1016/0002-8703(64)90408-9, 14110653.
    • (1964) Am Heart J , vol.67 , pp. 133-134
    • Freis, E.D.1
  • 6
    • 71949097507 scopus 로고    scopus 로고
    • Micropropagation of Gynura procumbens (Lour.) Merr. an important medicinal plant
    • Chan LK, Lim SY, Pan LP. Micropropagation of Gynura procumbens (Lour.) Merr. an important medicinal plant. Journal of Medicinal Plants Research 2009, 3:105-111.
    • (2009) Journal of Medicinal Plants Research , vol.3 , pp. 105-111
    • Chan, L.K.1    Lim, S.Y.2    Pan, L.P.3
  • 7
    • 0034060889 scopus 로고    scopus 로고
    • Effects of an ethanolic extract of Gynura procumbens on serum glucose, cholesterol and triglyceride levels in normal and Steptozotocin-induced diabetic rats
    • Zhang XF, Tan BKH. Effects of an ethanolic extract of Gynura procumbens on serum glucose, cholesterol and triglyceride levels in normal and Steptozotocin-induced diabetic rats. Singapore Med J 2000, 41:9-13.
    • (2000) Singapore Med J , vol.41 , pp. 9-13
    • Zhang, X.F.1    Tan, B.K.H.2
  • 8
    • 0038385269 scopus 로고    scopus 로고
    • Flavonoid identification and hypoglycaemic studies of the butanol fraction from Gynura procumbens
    • Akowuah GA, Sadikum A, Mariam A. Flavonoid identification and hypoglycaemic studies of the butanol fraction from Gynura procumbens. Pharm Biol 2002, 40:405-410.
    • (2002) Pharm Biol , vol.40 , pp. 405-410
    • Akowuah, G.A.1    Sadikum, A.2    Mariam, A.3
  • 11
    • 77951935453 scopus 로고    scopus 로고
    • Anti-ulcerogenic activity of Gynura procumbens leaf extract against experimentally-induced gastric lesions in rats
    • Mahmood AA, Mariod AA, Fouad A, Ibrahim SAW. Anti-ulcerogenic activity of Gynura procumbens leaf extract against experimentally-induced gastric lesions in rats. Journal of Medicinal Plants Research 2010, 4:686-691.
    • (2010) Journal of Medicinal Plants Research , vol.4 , pp. 686-691
    • Mahmood, A.A.1    Mariod, A.A.2    Fouad, A.3    Ibrahim, S.A.W.4
  • 12
    • 80052034243 scopus 로고    scopus 로고
    • Inhibition effect of Gynura procumbens extract on UV-B-induced matrix-metalloproteinase expression in human dermal fibroblasts
    • 10.1016/j.jep.2011.04.072, 21672616
    • Kim J, Lee CW, Kim EK, Lee SJ, Park NJ, Kim HS, Kim HK, Cha K, Jang YP, Kim JW. Inhibition effect of Gynura procumbens extract on UV-B-induced matrix-metalloproteinase expression in human dermal fibroblasts. J Ethnopharmacol 2011, 137:427-433. 10.1016/j.jep.2011.04.072, 21672616.
    • (2011) J Ethnopharmacol , vol.137 , pp. 427-433
    • Kim, J.1    Lee, C.W.2    Kim, E.K.3    Lee, S.J.4    Park, N.J.5    Kim, H.S.6    Kim, H.K.7    Cha, K.8    Jang, Y.P.9    Kim, J.W.10
  • 13
    • 67349167120 scopus 로고    scopus 로고
    • Toxicology evaluation of standardized methanol extract of Gynura procumbens
    • 10.1016/j.jep.2009.03.011, 19429368
    • Rosidah, Yam MF, Amirin S, Ahmad M, Akowuah GA, Zaini MA. Toxicology evaluation of standardized methanol extract of Gynura procumbens. J Ethnopharmacol 2009, 123:244-249. 10.1016/j.jep.2009.03.011, 19429368.
    • (2009) J Ethnopharmacol , vol.123 , pp. 244-249
    • Rosidah1    Yam, M.F.2    Amirin, S.3    Ahmad, M.4    Akowuah, G.A.5    Zaini, M.A.6
  • 16
    • 34147129657 scopus 로고    scopus 로고
    • Inhibition of angiotensin-converting enzyme activity by a partially purified fraction of Gynura procumbens in spontaneously hypertensive rats
    • 10.1159/000100391, 17409755
    • Hoe SZ, Kamaruddin MY, Lam SK. Inhibition of angiotensin-converting enzyme activity by a partially purified fraction of Gynura procumbens in spontaneously hypertensive rats. Med Princ Pract 2007, 16:203-208. 10.1159/000100391, 17409755.
    • (2007) Med Princ Pract , vol.16 , pp. 203-208
    • Hoe, S.Z.1    Kamaruddin, M.Y.2    Lam, S.K.3
  • 17
    • 79952939087 scopus 로고    scopus 로고
    • Gynura procumbens Merr. decreases blood pressure in rats by vasodilatation via inhibition of calcium channels
    • 10.1590/S1807-59322011000100025, 3044591, 21437451
    • Hoe SZ, Lee CN, Mok SL, Kamaruddin MY, Lam SK. Gynura procumbens Merr. decreases blood pressure in rats by vasodilatation via inhibition of calcium channels. Clinics 2011, 66:143-150. 10.1590/S1807-59322011000100025, 3044591, 21437451.
    • (2011) Clinics , vol.66 , pp. 143-150
    • Hoe, S.Z.1    Lee, C.N.2    Mok, S.L.3    Kamaruddin, M.Y.4    Lam, S.K.5
  • 18
    • 34249659071 scopus 로고    scopus 로고
    • Cardiovascular effects of the aqueous extract from Caesalpinia ferrea: Involvement of ATP-sensitive potassium channels
    • 10.1016/j.vph.2007.03.005, 17481959
    • Menezes IAC, Moreira IJA, Carvalho AA, Antoniollo AR, Santos MRV. Cardiovascular effects of the aqueous extract from Caesalpinia ferrea: Involvement of ATP-sensitive potassium channels. Vascul Pharmacol 2007, 47:41-47. 10.1016/j.vph.2007.03.005, 17481959.
    • (2007) Vascul Pharmacol , vol.47 , pp. 41-47
    • Menezes, I.A.C.1    Moreira, I.J.A.2    Carvalho, A.A.3    Antoniollo, A.R.4    Santos, M.R.V.5
  • 19
    • 78049264371 scopus 로고    scopus 로고
    • Hypotensive activity of an n-butanol extract and their purified compounds from leaves of Phyllanthus acidus (L.) Skeels in rats
    • 10.1016/j.ejphar.2010.09.038, 20868659
    • Leeya Y, Mulvany MJ, Queiroz EF, Marston A, Hostettmann KC, Jansakul C. Hypotensive activity of an n-butanol extract and their purified compounds from leaves of Phyllanthus acidus (L.) Skeels in rats. Eur J Pharmacol 2010, 649:301-313. 10.1016/j.ejphar.2010.09.038, 20868659.
    • (2010) Eur J Pharmacol , vol.649 , pp. 301-313
    • Leeya, Y.1    Mulvany, M.J.2    Queiroz, E.F.3    Marston, A.4    Hostettmann, K.C.5    Jansakul, C.6
  • 21
    • 0021187398 scopus 로고
    • Induction of Ca2+ influx and intracellular Ca2+ released in isolated rat aorta and mesenteric resistance vessels by norepinephrine activation of alpha-1-receptors
    • Cauvin C, Malik S. Induction of Ca2+ influx and intracellular Ca2+ released in isolated rat aorta and mesenteric resistance vessels by norepinephrine activation of alpha-1-receptors. J Pharmacol Exp Ther 1984, 230:413-418.
    • (1984) J Pharmacol Exp Ther , vol.230 , pp. 413-418
    • Cauvin, C.1    Malik, S.2
  • 23
    • 0021129775 scopus 로고
    • Calcium channels in smooth muscle
    • Karaki H, Weiss GB. Calcium channels in smooth muscle. Gastroenterology 1984, 87:960-970.
    • (1984) Gastroenterology , vol.87 , pp. 960-970
    • Karaki, H.1    Weiss, G.B.2
  • 24
    • 0019395657 scopus 로고
    • Evidence for two separated Ca2+ pathways in smooth muscle plasmalemma
    • 10.1007/BF01870817, 7241573
    • Meisheri KD, Hwang O, van Breemen C. Evidence for two separated Ca2+ pathways in smooth muscle plasmalemma. J Membr Biol 1981, 59:19-25. 10.1007/BF01870817, 7241573.
    • (1981) J Membr Biol , vol.59 , pp. 19-25
    • Meisheri, K.D.1    Hwang, O.2    van Breemen, C.3
  • 25
    • 0022560161 scopus 로고
    • Ca2+ compartments in saponin-skined cultured vascular smooth muscle cells
    • 10.1085/jgp.87.3.369, 2217615, 3514788
    • Yamamoto H, van Breemen C. Ca2+ compartments in saponin-skined cultured vascular smooth muscle cells. J Gen Physiol 1986, 87:369-389. 10.1085/jgp.87.3.369, 2217615, 3514788.
    • (1986) J Gen Physiol , vol.87 , pp. 369-389
    • Yamamoto, H.1    van Breemen, C.2
  • 26
    • 22044445432 scopus 로고    scopus 로고
    • Luteolin induces vasorelaxation in rat thoracic aorta via calcum and potassium channels
    • Jiang H, Xia Q, Wang X, Song J, Bruce IC. Luteolin induces vasorelaxation in rat thoracic aorta via calcum and potassium channels. Pharmazie 2005, 60:444-447.
    • (2005) Pharmazie , vol.60 , pp. 444-447
    • Jiang, H.1    Xia, Q.2    Wang, X.3    Song, J.4    Bruce, I.C.5
  • 27
    • 0030611208 scopus 로고    scopus 로고
    • Capacitative Ca2+ entry associated wuth the α1-adrenoceptors in rat aorta. Nauyn Shmiedeberg's Arch
    • Noguera MA, Ivora MD, Chulia S, D'Ocon P. Capacitative Ca2+ entry associated wuth the α1-adrenoceptors in rat aorta. Nauyn Shmiedeberg's Arch. Pharmacol 1997, 356:83-89.
    • (1997) Pharmacol , vol.356 , pp. 83-89
    • Noguera, M.A.1    Ivora, M.D.2    Chulia, S.3    D'Ocon, P.4
  • 28
    • 0026782044 scopus 로고
    • Mechanisms of caffeine induced contraction and relaxation of rat aortic smooth muscle
    • 1175678, 1338095
    • Watanabe C, Yamamoto H, Hirano K, Kobayashi S, Kanaide H. Mechanisms of caffeine induced contraction and relaxation of rat aortic smooth muscle. J Physiol 1992, 456:193-213. 1175678, 1338095.
    • (1992) J Physiol , vol.456 , pp. 193-213
    • Watanabe, C.1    Yamamoto, H.2    Hirano, K.3    Kobayashi, S.4    Kanaide, H.5
  • 29
    • 0027397544 scopus 로고
    • Inositol triphoshate and calcium signalling
    • 10.1038/361315a0, 8381210
    • Berridge MJ. Inositol triphoshate and calcium signalling. Nature 1993, 361:315-325. 10.1038/361315a0, 8381210.
    • (1993) Nature , vol.361 , pp. 315-325
    • Berridge, M.J.1
  • 30
    • 0027240615 scopus 로고
    • Do K+ channel openers relax smooth muscle by opening K+ channels?
    • Quast U. Do K+ channel openers relax smooth muscle by opening K+ channels?. Trends Pharmacol Sc 1993, 14:332-337.
    • (1993) Trends Pharmacol Sc , vol.14 , pp. 332-337
    • Quast, U.1
  • 31
    • 45749103308 scopus 로고    scopus 로고
    • Physiological roles of K+ channels in vascular smooth muscle cell
    • 10.1540/jsmr.44.65, 18552454
    • Eun AK, Jin H, In DJ, Won SP. Physiological roles of K+ channels in vascular smooth muscle cell. J Smooth Muscle Res 2008, 44:65-81. 10.1540/jsmr.44.65, 18552454.
    • (2008) J Smooth Muscle Res , vol.44 , pp. 65-81
    • Eun, A.K.1    Jin, H.2    In, D.J.3    Won, S.P.4
  • 32
    • 0029108913 scopus 로고
    • Physiological roles and properties of potassium channels in arterial smooth muscle
    • Nelson MT, Quayle JM. Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol Cell Physiol 1995, 268:799-822.
    • (1995) Am J Physiol Cell Physiol , vol.268 , pp. 799-822
    • Nelson, M.T.1    Quayle, J.M.2
  • 33
    • 77954632792 scopus 로고    scopus 로고
    • United States of America: McGraw-Hill Companies, Inc, 21
    • William FG. Review of Medical Physiology 2003, United States of America: McGraw-Hill Companies, Inc, 21.
    • (2003) Review of Medical Physiology
    • William, F.G.1
  • 34
    • 0025830419 scopus 로고
    • Cyclic GMP stimulates Na+/Ca2+ exchange in vascular smooth muscle cells in primary culture
    • Furukawa K, Ohshima N, Tawada-Iwata Y, Shigekawa M. Cyclic GMP stimulates Na+/Ca2+ exchange in vascular smooth muscle cells in primary culture. J Biol Chem 1991, 266:12337-12341.
    • (1991) J Biol Chem , vol.266 , pp. 12337-12341
    • Furukawa, K.1    Ohshima, N.2    Tawada-Iwata, Y.3    Shigekawa, M.4
  • 35
    • 0017094798 scopus 로고
    • An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
    • 10.1038/263663a0, 802670
    • Moncada S, Gryglewski RJ, Bunting S, Vane JR. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature 1976, 263:663-665. 10.1038/263663a0, 802670.
    • (1976) Nature , vol.263 , pp. 663-665
    • Moncada, S.1    Gryglewski, R.J.2    Bunting, S.3    Vane, J.R.4
  • 36
    • 0022559202 scopus 로고
    • Prostaglandin Biosynthesis and its Compartmentation in Vascular Smooth Muscle and Endothelial Cells
    • 10.1146/annurev.ph.48.030186.001343, 3085582
    • Smith WL. Prostaglandin Biosynthesis and its Compartmentation in Vascular Smooth Muscle and Endothelial Cells. Annu Rev Physiol 1986, 48:251-262. 10.1146/annurev.ph.48.030186.001343, 3085582.
    • (1986) Annu Rev Physiol , vol.48 , pp. 251-262
    • Smith, W.L.1
  • 37
    • 0032888049 scopus 로고    scopus 로고
    • Molecular and genetic basis of β2 -adrenergic receptor function
    • Stephen BL. Molecular and genetic basis of β2 -adrenergic receptor function. J Allergy Clin Immunol 1999, 104:42-46.
    • (1999) J Allergy Clin Immunol , vol.104 , pp. 42-46
    • Stephen, B.L.1
  • 38
    • 0031774720 scopus 로고    scopus 로고
    • International Union of Pharmacology. XVII. Classification of Muscarinic Acetylcholine Receptors
    • Caufield MP, Birdsall NJMB. International Union of Pharmacology. XVII. Classification of Muscarinic Acetylcholine Receptors. Pharmacol Rev 1998, 50:279-288.
    • (1998) Pharmacol Rev , vol.50 , pp. 279-288
    • Caufield, M.P.1    Birdsall, N.J.M.B.2
  • 39
    • 0023832466 scopus 로고
    • Effects of flavonoids on nonenzymic lipid peroxidation: Structure activity relationship
    • Ratty AK, Das NP. Effects of flavonoids on nonenzymic lipid peroxidation: Structure activity relationship. Biochem Med Metabol BioL 1988, 39:69-79.
    • (1988) Biochem Med Metabol BioL , vol.39 , pp. 69-79
    • Ratty, A.K.1    Das, N.P.2
  • 40
    • 0016906546 scopus 로고
    • The Flavonoids. A class of semi-essential food components: Their role in human nutrition
    • Kuhnau J. The Flavonoids. A class of semi-essential food components: Their role in human nutrition. Wld. Rev. Nutr. Diet 1976, 24:117-191.
    • (1976) Wld. Rev. Nutr. Diet , vol.24 , pp. 117-191
    • Kuhnau, J.1
  • 41
    • 84865322403 scopus 로고    scopus 로고
    • Antihypertensive properties of flavonoid-rich apple peel extract
    • 10.1016/j.foodchem.2012.07.023, 22980808
    • Balasuriya N, Rupasinghe HPV. Antihypertensive properties of flavonoid-rich apple peel extract. Food Chem 2012, 135:2320-2325. 10.1016/j.foodchem.2012.07.023, 22980808.
    • (2012) Food Chem , vol.135 , pp. 2320-2325
    • Balasuriya, N.1    Rupasinghe, H.P.V.2
  • 42
    • 84864643200 scopus 로고    scopus 로고
    • Evaluation of mechanism for antihypertensive action of Clerodendrum colebrookianum Walp., used by folklore healers in north-east India
    • 10.1016/j.jep.2012.06.025, 22732729
    • Lokesh D, Amitsankar D. Evaluation of mechanism for antihypertensive action of Clerodendrum colebrookianum Walp., used by folklore healers in north-east India. J Ethnopharmacol 2012, 143:207-212. 10.1016/j.jep.2012.06.025, 22732729.
    • (2012) J Ethnopharmacol , vol.143 , pp. 207-212
    • Lokesh, D.1    Amitsankar, D.2
  • 44
    • 0029867672 scopus 로고    scopus 로고
    • Flavonoids-Chemistry, metabolism, cardioprotective effects, and dietary sources
    • Cook NC, Samman S. Flavonoids-Chemistry, metabolism, cardioprotective effects, and dietary sources. J Nutr Biochem 1996, 7:66-76.
    • (1996) J Nutr Biochem , vol.7 , pp. 66-76
    • Cook, N.C.1    Samman, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.