Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele

BMC Genomics

Volumn 14, Issue 1, 2013, Pages

  Smagulova, Fatima ^a,c   Brick, Kevin ^b   Pu, Yongmei ^a   Sengupta, Uttara ^a,d   Camerini Otero, R Daniel ^b   Petukhova, Galina V ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c UNIVERSITÉ DE RENNES 1   (France)

^d ST MARK S HOSPITAL   (United Kingdom)

Author keywords

Double stranded DNA breaks; Homologous recombination; Recombination hotspots; SPO11; Subtelomeres

Indexed keywords

HISTONE H2AX; PROTEIN MLH1; SPO11 PROTEIN; TRANSCRIPTION FACTOR GAL4;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CELL POPULATION; CHROMOSOME PAIRING; CHROMOSOME STRUCTURE; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; FEMALE; GENE CLUSTER; GENE FREQUENCY; GENE MUTATION; GENE REPRESSION; GENETIC ASSOCIATION; GENETIC RECOMBINATION; HOMOLOGOUS RECOMBINATION; MALE; MITOTIC RECOMBINATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POSTTRANSCRIPTIONAL GENE SILENCING; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PSEUDOAUTOSOMAL REGION; SPO11 GENE; SUBTELOMERE; SYNAPTONEMAL COMPLEX; TRANSCRIPTION INITIATION SITE; X CHROMOSOME; Y CHROMOSOME;

ALLELES; ANIMALS; BINDING SITES; CHROMOSOME PAIRING; CLUSTER ANALYSIS; DNA BREAKS, DOUBLE-STRANDED; ENDODEOXYRIBONUCLEASES; GENE KNOCK-IN TECHNIQUES; GENOMICS; MICE; RECOMBINATION, GENETIC; TELOMERE;

MAMMALIA; MUS; SACCHAROMYCES; SACCHAROMYCETALES;

EID: 84880334340     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-14-493     Document Type: Article

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