Olig2-induced neural stem cell differentiation involves downregulation of Wnt signaling and induction of Dickkopf-1 expression

PLoS ONE

Volumn 3, Issue 12, 2008, Pages

  Ahn, Sung Min ^a   Byun, Kyunghee ^a   Kim, Deokhoon ^a   Lee, Kiyoung ^a   Yoo, Jong Shin ^b   Kim, Seung U ^a,c   Jho, Eek Hoon ^d   Simpson, Richard J ^e   Lee, Bonghee ^a  

^a Gachon University College of Medicine   (South Korea)

^b Korea Basic Science Institute (KBSI)   (South Korea)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d University of Seoul   (South Korea)

^e WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DICKKOPF 1 PROTEIN; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; TUMOR SUPPRESSOR PROTEIN; WNT PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BETA CATENIN; DKK1 PROTEIN, HUMAN; NERVE PROTEIN; OLIG2 PROTEIN, HUMAN; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTE; CANCER STEM CELL; CELL IMMORTALIZATION; CELL PROLIFERATION; CELL RENEWAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOWN REGULATION; DRUG MECHANISM; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; LYMPHOID CELL LINE; MICROARRAY ANALYSIS; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; OLIGODENDROGLIA; PROTEIN EXPRESSION; PROTEIN INDUCTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; CELL CULTURE; CELL DIFFERENTIATION; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; PHOSPHORYLATION; PHYSIOLOGY; STEM CELL; TISSUE DISTRIBUTION; VALIDATION STUDY;

BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BETA CATENIN; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DOWN-REGULATION; GENE EXPRESSION PROFILING; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; NERVE TISSUE PROTEINS; NEUROGENESIS; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STEM CELLS; TISSUE DISTRIBUTION; WNT PROTEINS;

EID: 58049097515     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003917     Document Type: Article

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