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Volumn 48, Issue 8, 2013, Pages 570-583

Use of ultrasound contrast agent microbubbles in preclinical research : Recommendations for small animal imaging

Author keywords

Microbubble; Recommendations; Small animal imaging; Ultrasound contrast agent; Ultrasound molecular imaging

Indexed keywords

ECHO CONTRAST MEDIUM; ISOFLURANE; MICROMARKER; NITROGEN; PERFLUBUTANE; PERFLUTREN; SONOVUE; TARGESTAR; UNCLASSIFIED DRUG; VISISTAR;

EID: 84880311732     PISSN: 00209996     EISSN: 15360210     Source Type: Journal    
DOI: 10.1097/RLI.0b013e318289f854     Document Type: Review
Times cited : (50)

References (68)
  • 1
    • 58149242457 scopus 로고    scopus 로고
    • Dexfenfluramine discontinuous treatment does not worsen hypoxia-induced pulmonary vascular remodeling but activates RhoA/ROCK pathway: Consequences on pulmonary hypertension
    • Desbuards N, Antier D, Rochefort GY, et al. Dexfenfluramine discontinuous treatment does not worsen hypoxia-induced pulmonary vascular remodeling but activates RhoA/ROCK pathway: Consequences on pulmonary hypertension. Eur J Pharmacol. 2009;602:355-363.
    • (2009) Eur J Pharmacol. , vol.602 , pp. 355-363
    • Desbuards, N.1    Antier, D.2    Rochefort, G.Y.3
  • 2
    • 48949117176 scopus 로고    scopus 로고
    • Echocardiography, a non-invasive method for the assessment of cardiac function and morphology in preclinical drug toxicology and safety pharmacology
    • Hanton G, Eder V, Rochefort G, et al. Echocardiography, a non-invasive method for the assessment of cardiac function and morphology in preclinical drug toxicology and safety pharmacology. Expert Opin Drug Metab Toxicol. 2008;4:681-696.
    • (2008) Expert Opin Drug Metab Toxicol. , vol.4 , pp. 681-696
    • Hanton, G.1    Eder, V.2    Rochefort, G.3
  • 3
    • 52049113198 scopus 로고    scopus 로고
    • Vessel fractions in tumor xenografts depicted by flow- or contrast-sensitive three-dimensional high-frequency Doppler ultrasound respond differently to antiangiogenic treatment
    • Palmowski M, Huppert J, Hauff P, et al. Vessel fractions in tumor xenografts depicted by flow- or contrast-sensitive three-dimensional high-frequency Doppler ultrasound respond differently to antiangiogenic treatment. Cancer Res. 2008; 68:7042-7049.
    • (2008) Cancer Res. , vol.68 , pp. 7042-7049
    • Palmowski, M.1    Huppert, J.2    Hauff, P.3
  • 4
    • 63649118905 scopus 로고    scopus 로고
    • Ultrasound contrast microbubbles in imaging and therapy: Physical principles and engineering
    • Qin S, Caskey CF, Ferrara KW. Ultrasound contrast microbubbles in imaging and therapy: Physical principles and engineering. Phys Med Biol. 2009; 54:R27-R57.
    • (2009) Phys Med Biol. , vol.54
    • Qin, S.1    Caskey, C.F.2    Ferrara, K.W.3
  • 6
    • 77953267632 scopus 로고    scopus 로고
    • Molecular ultrasound imaging: Current status and future directions
    • Deshpande N, Needles A,Willmann JK. Molecular ultrasound imaging: Current status and future directions. Clin Radiol. 2010;65:567-581.
    • (2010) Clin Radiol. , vol.65 , pp. 567-581
    • Deshpande, N.1    Needles, A.2    Willmann, J.K.3
  • 7
    • 77955147104 scopus 로고    scopus 로고
    • Science to practice: The dawn of molecular US imaging for clinical cancer imaging
    • Kiessling F. Science to practice: The dawn of molecular US imaging for clinical cancer imaging. Radiology. 2010;256:331-333.
    • (2010) Radiology. , vol.256 , pp. 331-333
    • Kiessling, F.1
  • 8
    • 74949107510 scopus 로고    scopus 로고
    • BR55: A lipopeptide-based VEGFR2- targeted ultrasound contrast agent for molecular imaging of angiogenesis
    • Pochon S, Tardy I, Bussat P, et al. BR55: A lipopeptide-based VEGFR2- targeted ultrasound contrast agent for molecular imaging of angiogenesis. Invest Radiol. 2010;45:89-95.
    • (2010) Invest Radiol. , vol.45 , pp. 89-95
    • Pochon, S.1    Tardy, I.2    Bussat, P.3
  • 9
    • 77955133884 scopus 로고    scopus 로고
    • Antiangiogenic cancer therapy: Monitoring with molecular US and a clinically translatable contrast agent (BR55
    • Pysz MA, Foygel K, Rosenberg J, et al. Antiangiogenic cancer therapy: Monitoring with molecular US and a clinically translatable contrast agent (BR55). Radiology. 2010;256:519-527.
    • (2010) Radiology. , vol.256 , pp. 519-527
    • Pysz, M.A.1    Foygel, K.2    Rosenberg, J.3
  • 10
    • 77957269295 scopus 로고    scopus 로고
    • Ultrasound molecular imaging of VEGFR2 in a rat prostate tumor model using BR55
    • Tardy I, Pochon S, Theraulaz M, et al. Ultrasound molecular imaging of VEGFR2 in a rat prostate tumor model using BR55. Invest Radiol. 2010; 45:573-578.
    • (2010) Invest Radiol. , vol.45 , pp. 573-578
    • Tardy, I.1    Pochon, S.2    Theraulaz, M.3
  • 11
    • 79952448809 scopus 로고    scopus 로고
    • Ultrasound molecular imaging of tumor angiogenesis with an integrin targeted microbubble contrast agent
    • Anderson CR, Hu X, Zhang H, et al. Ultrasound molecular imaging of tumor angiogenesis with an integrin targeted microbubble contrast agent. Invest Radiol. 2011;46:215-224.
    • (2011) Invest Radiol. , vol.46 , pp. 215-224
    • Anderson, C.R.1    Hu, X.2    Zhang, H.3
  • 12
    • 77950344627 scopus 로고    scopus 로고
    • Targeted contrast-enhanced ultrasound imaging of tumor angiogenesis with contrast microbubbles conjugated to integrin-binding knottin peptides
    • Willmann JK, Kimura RH, Deshpande N, et al. Targeted contrast-enhanced ultrasound imaging of tumor angiogenesis with contrast microbubbles conjugated to integrin-binding knottin peptides. J Nucl Med. 2010;51:433-440.
    • (2010) J Nucl Med. , vol.51 , pp. 433-440
    • Willmann, J.K.1    Kimura, R.H.2    Deshpande, N.3
  • 13
    • 51549083693 scopus 로고    scopus 로고
    • Dual-targeted contrast agent for US assessment of tumor angiogenesis in vivo
    • Willmann JK, Lutz AM, Paulmurugan R, et al. Dual-targeted contrast agent for US assessment of tumor angiogenesis in vivo. Radiology. 2008;248:936-944.
    • (2008) Radiology. , vol.248 , pp. 936-944
    • Willmann, J.K.1    Lutz, A.M.2    Paulmurugan, R.3
  • 14
    • 70350621516 scopus 로고    scopus 로고
    • Dual targeting improves microbubble contrast agent adhesion to VCAM-1 and P-selectin under flow
    • Ferrante EA, Pickard JE, Rychak J, et al. Dual targeting improves microbubble contrast agent adhesion to VCAM-1 and P-selectin under flow. J Control Release. 2009;140:100-107.
    • (2009) J Control Release. , vol.140 , pp. 100-107
    • Ferrante, E.A.1    Pickard, J.E.2    Rychak, J.3
  • 15
    • 73849092887 scopus 로고    scopus 로고
    • Molecular imaging of the initial inflammatory response in atherosclerosis: Implications for early detection of disease
    • Kaufmann BA, Carr CL, Belcik JT, et al. Molecular imaging of the initial inflammatory response in atherosclerosis: Implications for early detection of disease. Arterioscler Thromb Vasc Biol. 2010;30:54-59.
    • (2010) Arterioscler Thromb Vasc Biol. , vol.30 , pp. 54-59
    • Kaufmann, B.A.1    Carr, C.L.2    Belcik, J.T.3
  • 16
    • 34948901570 scopus 로고    scopus 로고
    • Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow
    • Klibanov AL, Rychak JJ, Yang WC, et al. Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow. Contrast Media Mol Imaging. 2006;1:259-266.
    • (2006) Contrast Media Mol Imaging. , vol.1 , pp. 259-266
    • Klibanov, A.L.1    Rychak, J.J.2    Yang, W.C.3
  • 17
    • 33846421119 scopus 로고    scopus 로고
    • Myocardial ischemic memory imaging with molecular echocardiography
    • Villanueva FS, Lu E, Bowry S, et al. Myocardial ischemic memory imaging with molecular echocardiography. Circulation. 2007;115:345-352.
    • (2007) Circulation. , vol.115 , pp. 345-352
    • Villanueva, F.S.1    Lu, E.2    Bowry, S.3
  • 18
    • 23044493517 scopus 로고    scopus 로고
    • Ultrasound derived imaging and quantification of cell adhesion molecules in experimental autoimmune encephalomyelitis (EAE) by sensitive particle acoustic quantification (SPAQ
    • Reinhardt M, Hauff P, Linker RA, et al. Ultrasound derived imaging and quantification of cell adhesion molecules in experimental autoimmune encephalomyelitis (EAE) by sensitive particle acoustic quantification (SPAQ). NeuroImage. 2005;27:267-278.
    • (2005) NeuroImage. , vol.27 , pp. 267-278
    • Reinhardt, M.1    Hauff, P.2    Linker, R.A.3
  • 19
    • 39749095082 scopus 로고    scopus 로고
    • Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS)-update 2008
    • Claudon M, Cosgrove D, Albrecht T, et al. Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS)-update 2008. Ultraschall Med. 2008;29:28-44.
    • (2008) Ultraschall Med. , vol.29 , pp. 28-44
    • Claudon, M.1    Cosgrove, D.2    Albrecht, T.3
  • 20
    • 60749111476 scopus 로고    scopus 로고
    • Guidelines for contrast enhanced ultrasound (CEUS)-update 2008 [in French]
    • Correas JM, Tranquart F, Claudon M. Guidelines for contrast enhanced ultrasound (CEUS)-update 2008 [in French]. J Radiol. 2009;90:123-138.
    • (2009) J Radiol. , vol.90 , pp. 123-138
    • Correas, J.M.1    Tranquart, F.2    Claudon, M.3
  • 21
    • 77957033839 scopus 로고    scopus 로고
    • EFSUMB-guidelines for CEUS are directive and effective [in German]
    • Seitz K. EFSUMB-guidelines for CEUS are directive and effective [in German]. Ultraschall Med. 2010;31:225-227.
    • (2010) Ultraschall Med. , vol.31 , pp. 225-227
    • Seitz, K.1
  • 22
    • 79952505974 scopus 로고    scopus 로고
    • Pitfalls and artefacts using contrast enhanced ultrasound
    • Dietrich CF, Ignee A, Hocke M, et al. Pitfalls and artefacts using contrast enhanced ultrasound. Z Gastroenterol. 2011;49:350-356.
    • (2011) Z Gastroenterol. , vol.49 , pp. 350-356
    • Dietrich, C.F.1    Ignee, A.2    Hocke, M.3
  • 23
    • 34948816575 scopus 로고    scopus 로고
    • In vivo characterization of murine myocardial perfusion with myocardial contrast echocardiography: Validation and application in nitric oxide synthase 3 deficient mice
    • Raher MJ, Thibault H, Poh KK, et al. In vivo characterization of murine myocardial perfusion with myocardial contrast echocardiography: Validation and application in nitric oxide synthase 3 deficient mice. Circulation. 2007; 116:1250-1257.
    • (2007) Circulation. , vol.116 , pp. 1250-1257
    • Raher, M.J.1    Thibault, H.2    Poh, K.K.3
  • 25
    • 77957253179 scopus 로고    scopus 로고
    • ScVEGF microbubble ultrasound contrast agents: A novel probe for ultrasound molecular imaging of tumor angiogenesis
    • Anderson CR, Rychak JJ, Backer M, et al. scVEGF microbubble ultrasound contrast agents: A novel probe for ultrasound molecular imaging of tumor angiogenesis. Invest Radiol. 2010;45:579-585.
    • (2010) Invest Radiol. , vol.45 , pp. 579-585
    • Anderson, C.R.1    Rychak, J.J.2    Backer, M.3
  • 26
    • 77957259579 scopus 로고    scopus 로고
    • An ultrasound contrast agent targeted to P-selectin detects activated platelets at supra-arterial shear flow conditions
    • Guenther F, von zur Muhlen C, Ferrante EA, et al. An ultrasound contrast agent targeted to P-selectin detects activated platelets at supra-arterial shear flow conditions. Invest Radiol. 2010;45:586-591.
    • (2010) Invest Radiol. , vol.45 , pp. 586-591
    • Guenther, F.1    Von Zur Muhlen, C.2    Ferrante, E.A.3
  • 27
    • 39549106031 scopus 로고    scopus 로고
    • US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice
    • Willmann JK, Paulmurugan R, Chen K, et al. US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice. Radiology. 2008;246:508-518.
    • (2008) Radiology. , vol.246 , pp. 508-518
    • Willmann, J.K.1    Paulmurugan, R.2    Chen, K.3
  • 29
    • 84860109665 scopus 로고    scopus 로고
    • Quantitative contrast-enhanced ultrasound imaging: A review of sources of variability
    • Tang MX, Mulvana H, Gauthier T, et al. Quantitative contrast-enhanced ultrasound imaging: A review of sources of variability. Interface Focus. 2011; 1:520-539.
    • (2011) Interface Focus. , vol.1 , pp. 520-539
    • Tang, M.X.1    Mulvana, H.2    Gauthier, T.3
  • 30
    • 23844438613 scopus 로고    scopus 로고
    • Assessment of microvascular perfusion changes in a rat breast tumor model using SonoVue to monitor the effects of different anti-angiogenic therapies
    • Broillet A, Hantson J, Ruegg C, et al. Assessment of microvascular perfusion changes in a rat breast tumor model using SonoVue to monitor the effects of different anti-angiogenic therapies. Acad Radiol. 2005;12(suppl 1):S28-S33.
    • (2005) Acad Radiol. , vol.12 , Issue.SUPPL. 1
    • Broillet, A.1    Hantson, J.2    Ruegg, C.3
  • 31
    • 77449158077 scopus 로고    scopus 로고
    • Noninvasive contrast-enhanced US quantitative assessment of tumor microcirculation in a murine model: Effect of discontinuing anti-VEGF therapy
    • Guibal A, Taillade L, Mule S, et al. Noninvasive contrast-enhanced US quantitative assessment of tumor microcirculation in a murine model: Effect of discontinuing anti-VEGF therapy. Radiology. 2010;254:420-429.
    • (2010) Radiology. , vol.254 , pp. 420-429
    • Guibal, A.1    Taillade, L.2    Mule, S.3
  • 32
    • 77955543678 scopus 로고    scopus 로고
    • Contrast ultrasonography: Necessity of linear data processing for the quantification of tumor vascularization
    • Peronneau P, Lassau N, Leguerney I, et al. Contrast ultrasonography: Necessity of linear data processing for the quantification of tumor vascularization. Ultraschall Med. 2010;31:370-378.
    • (2010) Ultraschall Med. , vol.31 , pp. 370-378
    • Peronneau, P.1    Lassau, N.2    Leguerney, I.3
  • 33
    • 29244442914 scopus 로고    scopus 로고
    • Quantitative analysis of myocardial perfusion in rats by contrast echocardiography
    • Thibault H, Lafitte S, Timperley J, et al. Quantitative analysis of myocardial perfusion in rats by contrast echocardiography. J Am Soc Echocardiogr. 2005; 18:1321-1328.
    • (2005) J Am Soc Echocardiogr. , vol.18 , pp. 1321-1328
    • Thibault, H.1    Lafitte, S.2    Timperley, J.3
  • 34
    • 78650947247 scopus 로고    scopus 로고
    • Contrast enhanced maximum intensity projection ultrasound imaging for assessing angiogenesis in murine glioma and breast tumor models: A comparative study
    • Forsberg F, Ro RJ, Fox TB, et al. Contrast enhanced maximum intensity projection ultrasound imaging for assessing angiogenesis in murine glioma and breast tumor models: A comparative study. Ultrasonics. 2011;51:382-389.
    • (2011) Ultrasonics. , vol.51 , pp. 382-389
    • Forsberg, F.1    Ro, R.J.2    Fox, T.B.3
  • 35
    • 66749183436 scopus 로고    scopus 로고
    • Monitoring angiogenesis in human melanoma xenograft model using contrast-enhanced ultrasound imaging
    • Forsberg F, Ro RJ, Liu JB, et al. Monitoring angiogenesis in human melanoma xenograft model using contrast-enhanced ultrasound imaging. Ultrason Imaging. 2008;30:237-246.
    • (2008) Ultrason Imaging. , vol.30 , pp. 237-246
    • Forsberg, F.1    Ro, R.J.2    Liu, J.B.3
  • 36
    • 38449111806 scopus 로고    scopus 로고
    • Dose-response relationship of ultrasound contrast agent in an in vivo murine melanoma model
    • Seiler GS, Ziemer LS, Schultz S, et al. Dose-response relationship of ultrasound contrast agent in an in vivo murine melanoma model. Cancer Imaging. 2007;7:216-223.
    • (2007) Cancer Imaging. , vol.7 , pp. 216-223
    • Seiler, G.S.1    Ziemer, L.S.2    Schultz, S.3
  • 37
    • 69049107408 scopus 로고    scopus 로고
    • Ultrasonic characterization of ultrasound contrast agents
    • de Jong N, Emmer M, van Wamel A, et al. Ultrasonic characterization of ultrasound contrast agents. Med Biol Eng Comput. 2009;47:861-873.
    • (2009) Med Biol Eng Comput. , vol.47 , pp. 861-873
    • De Jong, N.1    Emmer, M.2    Van Wamel, A.3
  • 38
    • 38549138696 scopus 로고    scopus 로고
    • Molecular imaging of vascular endothelial growth factor receptor 2 expression using targeted contrast-enhanced high-frequency ultrasonography
    • Lyshchik A, Fleischer AC, Huamani J, et al. Molecular imaging of vascular endothelial growth factor receptor 2 expression using targeted contrast-enhanced high-frequency ultrasonography. J UltrasoundMed. 2007;26:1575-1586.
    • (2007) J UltrasoundMed. , vol.26 , pp. 1575-1586
    • Lyshchik, A.1    Fleischer, A.C.2    Huamani, J.3
  • 39
    • 34547580851 scopus 로고    scopus 로고
    • Molecular imaging of inflammation in atherosclerosis with targeted ultrasound detection of vascular cell adhesion molecule-1
    • Kaufmann BA, Sanders JM, Davis C, et al. Molecular imaging of inflammation in atherosclerosis with targeted ultrasound detection of vascular cell adhesion molecule-1. Circulation. 2007;116:276-284.
    • (2007) Circulation. , vol.116 , pp. 276-284
    • Kaufmann, B.A.1    Sanders, J.M.2    Davis, C.3
  • 40
    • 0034154869 scopus 로고    scopus 로고
    • Detection procedures of ultrasound contrast agents
    • de Jong N, Frinking PJ, Bouakaz A, et al. Detection procedures of ultrasound contrast agents. Ultrasonics. 2000;38:87-92.
    • (2000) Ultrasonics. , vol.38 , pp. 87-92
    • De Jong, N.1    Frinking, P.J.2    Bouakaz, A.3
  • 41
    • 0034233024 scopus 로고    scopus 로고
    • Ultrasound contrast imaging: Current and new potential methods
    • Frinking PJ, Bouakaz A, Kirkhorn J, et al. Ultrasound contrast imaging: Current and new potential methods. Ultrasound Med Biol. 2000;26:965-975.
    • (2000) Ultrasound Med Biol. , vol.26 , pp. 965-975
    • Frinking, P.J.1    Bouakaz, A.2    Kirkhorn, J.3
  • 42
    • 33746821518 scopus 로고    scopus 로고
    • A new formalism for the quantification of tissue perfusion by the destruction-replenishment method in contrast ultrasound imaging
    • Arditi M, Frinking PJ, Zhou X, et al. A new formalism for the quantification of tissue perfusion by the destruction-replenishment method in contrast ultrasound imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2006; 53:1118-1129.
    • (2006) IEEE Trans Ultrason Ferroelectr Freq Control. , vol.53 , pp. 1118-1129
    • Arditi, M.1    Frinking, P.J.2    Zhou, X.3
  • 43
    • 44949227010 scopus 로고    scopus 로고
    • Evaluation of early response to antiangiogenic treatment with dynamic contrast enhanced ultrasound [in French]
    • Lassau N, Brule A, Chami L, et al. Evaluation of early response to antiangiogenic treatment with dynamic contrast enhanced ultrasound [in French]. J Radiol. 2008;89:549-555.
    • (2008) J Radiol. , vol.89 , pp. 549-555
    • Lassau, N.1    Brule, A.2    Chami, L.3
  • 44
    • 40349113040 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced ultrasonography (DCE-US) with quantification of tumor perfusion: A new diagnostic tool to evaluate the early effects of antiangiogenic treatment
    • Lassau N, Chami L, Benatsou B, et al. Dynamic contrast-enhanced ultrasonography (DCE-US) with quantification of tumor perfusion: A new diagnostic tool to evaluate the early effects of antiangiogenic treatment. Eur Radiol. 2007; 17(suppl 6):F89-F98.
    • (2007) Eur Radiol. , vol.17 , Issue.SUPPL. 6
    • Lassau, N.1    Chami, L.2    Benatsou, B.3
  • 45
    • 78149274559 scopus 로고    scopus 로고
    • Parametric imaging for characterizing focal liver lesions in contrast-enhanced ultrasound
    • Rognin NG, Arditi M, Mercier L, et al. Parametric imaging for characterizing focal liver lesions in contrast-enhanced ultrasound. IEEE Trans Ultrason Ferroelectr Freq Control. 2010;57:2503-2511.
    • (2010) IEEE Trans Ultrason Ferroelectr Freq Control. , vol.57 , pp. 2503-2511
    • Rognin, N.G.1    Arditi, M.2    Mercier, L.3
  • 46
    • 84859142311 scopus 로고    scopus 로고
    • Use of intravital microscopy to study the microvascular behavior of microbubble-based ultrasound contrast agents
    • Schneider M, Broillet A, Tardy I, et al. Use of intravital microscopy to study the microvascular behavior of microbubble-based ultrasound contrast agents. Microcirculation. 2012;19:245-259.
    • (2012) Microcirculation. , vol.19 , pp. 245-259
    • Schneider, M.1    Broillet, A.2    Tardy, I.3
  • 47
    • 11144327114 scopus 로고    scopus 로고
    • Sensitive particle acoustic quantification (SPAQ): A new ultrasound-based approach for the quantification of ultrasound contrast media in high concentrations
    • Reinhardt M, Hauff P, Briel A, et al. Sensitive particle acoustic quantification (SPAQ): A new ultrasound-based approach for the quantification of ultrasound contrast media in high concentrations. Invest Radiol. 2005;40:2-7.
    • (2005) Invest Radiol. , vol.40 , pp. 2-7
    • Reinhardt, M.1    Hauff, P.2    Briel, A.3
  • 48
    • 79956158987 scopus 로고    scopus 로고
    • Characterizing the subharmonic response of phospholipid-coated microbubbles for carotid imaging
    • Faez T, Emmer M, Docter M, et al. Characterizing the subharmonic response of phospholipid-coated microbubbles for carotid imaging. Ultrasound Med Biol. 2011;37:958-970.
    • (2011) Ultrasound Med Biol. , vol.37 , pp. 958-970
    • Faez, T.1    Emmer, M.2    Docter, M.3
  • 49
    • 80053195512 scopus 로고    scopus 로고
    • Dynamic manipulation of the subharmonic scattering of phospholipid-coated microbubbles
    • Faez T, Renaud G, Defontaine M, et al. Dynamic manipulation of the subharmonic scattering of phospholipid-coated microbubbles. Phys Med Biol. 2011;56:6459-6473.
    • (2011) Phys Med Biol. , vol.56 , pp. 6459-6473
    • Faez, T.1    Renaud, G.2    Defontaine, M.3
  • 50
    • 84855300532 scopus 로고    scopus 로고
    • Assessment of molecular imaging of angiogenesis with three-dimensional ultrasonography
    • Streeter JE, Gessner RC, Tsuruta J, et al. Assessment of molecular imaging of angiogenesis with three-dimensional ultrasonography. Mol Imaging. 2011; 10:460-468.
    • (2011) Mol Imaging. , vol.10 , pp. 460-468
    • Streeter, J.E.1    Gessner, R.C.2    Tsuruta, J.3
  • 51
    • 84868108537 scopus 로고    scopus 로고
    • Volumetric contrast-enhanced ultrasound imaging to assess early response to apoptosis-inducing anti-death receptor 5 antibody therapy in a breast cancer animal model
    • Hoyt K, Sorace A, Saini R. Volumetric contrast-enhanced ultrasound imaging to assess early response to apoptosis-inducing anti-death receptor 5 antibody therapy in a breast cancer animal model. J Ultrasound Med. 2012;31: 1759-1766.
    • (2012) J Ultrasound Med. , vol.31 , pp. 1759-1766
    • Hoyt, K.1    Sorace, A.2    Saini, R.3
  • 52
    • 84864883881 scopus 로고    scopus 로고
    • Ultrasound molecular imaging contrast agent binding to both E- and P-selectin in different species
    • Bettinger T, Bussat P, Tardy I, et al. Ultrasound molecular imaging contrast agent binding to both E- and P-selectin in different species. Invest Radiol. 2012;47:516-523.
    • (2012) Invest Radiol. , vol.47 , pp. 516-523
    • Bettinger, T.1    Bussat, P.2    Tardy, I.3
  • 53
    • 79955049240 scopus 로고    scopus 로고
    • Quantitative assessment of tumor blood flow in mice after treatment with different doses of an antiangiogenic agent with contrast-enhanced destruction-replenishment US
    • Zhou JH, Cao LH, Liu JB, et al. Quantitative assessment of tumor blood flow in mice after treatment with different doses of an antiangiogenic agent with contrast-enhanced destruction-replenishment US. Radiology. 2011;259:406-413.
    • (2011) Radiology. , vol.259 , pp. 406-413
    • Zhou, J.H.1    Cao, L.H.2    Liu, J.B.3
  • 54
    • 33744821896 scopus 로고    scopus 로고
    • Angiogenesis: Noninvasive quantitative assessment with contrast-enhanced functional US in murine model
    • Lucidarme O, Kono Y, Corbeil J, et al. Angiogenesis: Noninvasive quantitative assessment with contrast-enhanced functional US in murine model. Radiology. 2006;239:730-739.
    • (2006) Radiology. , vol.239 , pp. 730-739
    • Lucidarme, O.1    Kono, Y.2    Corbeil, J.3
  • 55
    • 77953873752 scopus 로고    scopus 로고
    • Comparison of conventional time-intensity curves vs. maximum intensity over time for post-processing of dynamic contrast-enhanced ultrasound
    • Palmowski M, Lederle W, Gaetjens J, et al. Comparison of conventional time-intensity curves vs. maximum intensity over time for post-processing of dynamic contrast-enhanced ultrasound. Eur J Radiol. 2010;75:e149-e153.
    • (2010) Eur J Radiol. , vol.75
    • Palmowski, M.1    Lederle, W.2    Gaetjens, J.3
  • 56
    • 79751536352 scopus 로고    scopus 로고
    • Assessment and monitoring tumor vascularity with contrast-enhanced ultrasound maximum intensity persistence imaging
    • PyszMA, Foygel K, Panje CM, et al. Assessment and monitoring tumor vascularity with contrast-enhanced ultrasound maximum intensity persistence imaging. Invest Radiol. 2011;46:187-195.
    • (2011) Invest Radiol. , vol.46 , pp. 187-195
    • Pysz, M.A.1    Foygel, K.2    Panje, C.M.3
  • 57
    • 84864715062 scopus 로고    scopus 로고
    • Development and validation of an intrinsic landmark-based gating protocol applicable for functional and molecular ultrasound imaging
    • Grouls C, Hatting M, Tardy I, et al. Development and validation of an intrinsic landmark-based gating protocol applicable for functional and molecular ultrasound imaging. Eur Radiol. 2012;22:1789-1796.
    • (2012) Eur Radiol. , vol.22 , pp. 1789-1796
    • Grouls, C.1    Hatting, M.2    Tardy, I.3
  • 58
    • 84865137691 scopus 로고    scopus 로고
    • Quantitative assessment of tumor angiogenesis using real-time motion-compensated contrast-enhanced ultrasound imaging
    • PyszMA, Guracar I, Foygel K, et al. Quantitative assessment of tumor angiogenesis using real-time motion-compensated contrast-enhanced ultrasound imaging. Angiogenesis. 2012;15:433-442.
    • (2012) Angiogenesis. , vol.15 , pp. 433-442
    • Pysz, M.A.1    Guracar, I.2    Foygel, K.3
  • 59
    • 36048963222 scopus 로고    scopus 로고
    • Study of two devices used to maintain normothermia in rats and mice during general anesthesia
    • Taylor DK. Study of two devices used to maintain normothermia in rats and mice during general anesthesia. J Am Assoc Lab Anim Sci. 2007;46:37-41.
    • (2007) J Am Assoc Lab Anim Sci. , vol.46 , pp. 37-41
    • Taylor, D.K.1
  • 60
    • 0031833649 scopus 로고    scopus 로고
    • Localized hypothermia: Impact on oxygenation, microregional perfusion, metabolic and bioenergetic status of subcutaneous rat tumours
    • Kelleher DK, Nauth C, Thews O, et al. Localized hypothermia: Impact on oxygenation, microregional perfusion, metabolic and bioenergetic status of subcutaneous rat tumours. Br J Cancer. 1998;78:56-61.
    • (1998) Br J Cancer. , vol.78 , pp. 56-61
    • Kelleher, D.K.1    Nauth, C.2    Thews, O.3
  • 61
    • 0032411005 scopus 로고    scopus 로고
    • Blood flow rate in normal and tumorbearing rats in conscious state, under urethane anesthesia, and during systemic hypothermia
    • Sakaeda T, Fukumura K, Takahashi K, et al. Blood flow rate in normal and tumorbearing rats in conscious state, under urethane anesthesia, and during systemic hypothermia. J Drug Target. 1998;6:261-272.
    • (1998) J Drug Target. , vol.6 , pp. 261-272
    • Sakaeda, T.1    Fukumura, K.2    Takahashi, K.3
  • 62
    • 17544391940 scopus 로고    scopus 로고
    • Dissolution of multicomponent microbubbles in the bloodstream: 2. Experiment
    • Kabalnov A, Bradley J, Flaim S, et al. Dissolution of multicomponent microbubbles in the bloodstream: 2. Experiment. Ultrasound Med Biol. 1998; 24:751-760.
    • (1998) Ultrasound Med Biol. , vol.24 , pp. 751-760
    • Kabalnov, A.1    Bradley, J.2    Flaim, S.3
  • 63
    • 0032100726 scopus 로고    scopus 로고
    • Dissolution of multicomponent microbubbles in the bloodstream: 1. Theory
    • Kabalnov A, Klein D, Pelura T, et al. Dissolution of multicomponent microbubbles in the bloodstream: 1. Theory. Ultrasound Med Biol. 1998;24:739-749.
    • (1998) Ultrasound Med Biol. , vol.24 , pp. 739-749
    • Kabalnov, A.1    Klein, D.2    Pelura, T.3
  • 64
    • 84861481631 scopus 로고    scopus 로고
    • The effect of inhaled gases on ultrasound contrast agent longevity in vivo
    • Itani M, Mattrey RF. The effect of inhaled gases on ultrasound contrast agent longevity in vivo. Mol Imaging Biol. 2012;14:40-46.
    • (2012) Mol Imaging Biol. , vol.14 , pp. 40-46
    • Itani, M.1    Mattrey, R.F.2
  • 65
    • 79959549137 scopus 로고    scopus 로고
    • Effect of anesthesia carrier gas on in vivo circulation times of ultrasound microbubble contrast agents in rats
    • Mullin L, Gessner R, Kwan J, et al. Effect of anesthesia carrier gas on in vivo circulation times of ultrasound microbubble contrast agents in rats. Contrast Media Mol Imaging. 2011;6:126-131.
    • (2011) Contrast Media Mol Imaging. , vol.6 , pp. 126-131
    • Mullin, L.1    Gessner, R.2    Kwan, J.3
  • 66
    • 77957945760 scopus 로고    scopus 로고
    • Perfusion quantification using dynamic contrast-enhanced ultrasound: The impact of dynamic range and gain on timeintensity curves
    • Gauthier TP, Averkiou MA, Leen EL. Perfusion quantification using dynamic contrast-enhanced ultrasound: The impact of dynamic range and gain on timeintensity curves. Ultrasonics. 2011;51:102-106.
    • (2011) Ultrasonics. , vol.51 , pp. 102-106
    • Gauthier, T.P.1    Averkiou, M.A.2    Leen, E.L.3
  • 67
    • 67649382721 scopus 로고    scopus 로고
    • In vivo perfusion quantification by contrast ultrasound: Validation of the use of linearized video data vs. raw RF data
    • Rognin NG, Frinking P, Costa M, et al. In vivo perfusion quantification by contrast ultrasound: Validation of the use of linearized video data vs. raw RF data. In Ultrasonics Symp IUS 2008 IEEE. 2008:1690-1693.
    • (2008) Ultrasonics Symp IUS 2008 IEEE. , pp. 1690-1693
    • Rognin, N.G.1    Frinking, P.2    Costa, M.3
  • 68
    • 84455206551 scopus 로고    scopus 로고
    • Quantification and monitoring of inflammation in murine inflammatory bowel disease with targeted contrast-enhanced US
    • Deshpande N, Lutz AM, Ren Y, et al. Quantification and monitoring of inflammation in murine inflammatory bowel disease with targeted contrast-enhanced US. Radiology. 2012;262:172-180.
    • (2012) Radiology. , vol.262 , pp. 172-180
    • Deshpande, N.1    Lutz, A.M.2    Ren, Y.3


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