Dissolution of multicomponent microbubbles in the bloodstream: 1. Theory

Ultrasound in Medicine and Biology

Volumn 24, Issue 5, 1998, Pages 739-749

  Kabalnov, Alexey ^a   Klein, David ^a   Pelura, Timothy ^a   Schutt, Ernest ^a   Weers, Jeffry ^a  

^a Alliance Pharmaceutical Corporation   (United States)

Author keywords

Dissolution kinetics; Echocardiography; Epstein Plesset theory; Microballoons; Microbubbles; Microshells; Molecular diffusion; Ostwald coefficient; Ultrasound contrast media; Ultrasound scattering

Indexed keywords

BLOOD; BUBBLES (IN FLUIDS); DIFFUSION IN GASES; DISSOLUTION; METABOLISM; MOLECULAR DYNAMICS; OSMOSIS; SURFACE TESTING; SWELLING; ULTRASONIC SCATTERING; VAPOR PRESSURE;

EPSTEIN-PLESSET THEORY; MICROBUBBLES; OSTWALD COEFFICIENT;

ECHOCARDIOGRAPHY;

CONTRAST MEDIUM; MICROSPHERE; OSMOTIC AGENT;

AIR; ARTICLE; BLOOD PRESSURE; CONTRAST ENHANCEMENT; DIFFUSION COEFFICIENT; DISSOLUTION; ECHOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; OXYGEN CONSUMPTION; PARTICLE SIZE; PRIORITY JOURNAL; SOLUBILITY; SURFACE TENSION; ULTRASOUND;

EID: 0032100726     PISSN: 03015629     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-5629(98)00034-9     Document Type: Article

References (35)

1. F.G. Balen C.M. Allen W.R. Lees Ultrasound contrast agents Clin Radiol 49 1994 77 82
2. Bernstein H, Straub JA, Brush HT, Wing Richard E. Microencapsulated fluorinated gases for use as imaging agents. US Patent No. 5611344, 1997.
3. M.E. Burkard H.D. Van Liew Simulation of exchanges of multiple gases in bubbles in the body Resp Physiol 95 1994 131 145
4. J.M. Correas S.D. Quay EchoGen emulsion A new ultrasound contrast agent based on phase shift colloids Clin Radiol 51 Suppl 1 1996 11 14
5. J. Crank The Mathematics of Diffusion 1975 Clarendon Press Oxford
6. de Jong N. Acoustic Properties of Ultrasound Contrast Agents, Ph.D. thesis. Rotterdam, The Netherlands; Erasmus University, 1993.
7. P.S. Epstein M.S. Plesset On the stability of gas bubbles in liquid-gas solutions J Chem Phys 18 1950 1505 1509
8. D.F. Evans H. Wennerström Colloidal domain 1994 VCH Publishers New York
9. T. Fritzsch R. Schlief Future prospects for echo-enhancing agents Clin Radiol 51 Suppl 1 1996 56 58
10. B.B. Goldberg J.-B. Liu F. Forsberg Ultrasound contrast agents A review Ultrasound Med Biol 20 1994 319
11. R. Gramiak P.M. Shah Echocardiography of the aortic root Invest Radiol 3 1968 356 366
12. W. Hayduk H. Laudie Prediction of diffusion coefficients for nonelectrolytes in dilute aqueous solutions AIChE J 20 1974 611 615
13. A.S. Kabalnov A.V. Pertsov E.D. Shchukin Ostwald ripening in two-component disperse phase systems application to emulsion stability Coll Surf 24 1987 19 32
14. A.S. Kabalnov K.N. Makarov O.V. Shcherbakova Solubility of fluorocarbon in water as a key parameter determining fluorocarbon emulsion stability J Fluor Chem 50 1990 271 284
15. Kabalnov A, Weers JG, Schutt EA. Gas emulsions stabilized with fluorinated ethers having low ostwald coefficients. US Patent Application No. 08/479,621, 1995.
16. R.G. Laughlin The Aqueous Phase Behavior of Surfactants 1996 Academic Press San Diego
17. D.D. Lawson J. Moacanin K.V. Scherer Jr T.F. Terranova J.D. Ingham Methods for the estimation of vapor properties and oxygen solubilities of fluorochemicals for possible application in artificial blood formulations J Fluor Chem 12 1978 221 236
18. D.R. Lide CRC Handbook of Chemistry and Physics 1991 CRC Press Boca Raton
19. Lohrmann R. Gas-filled microspheres with fluorine-containing shells. US Patent No 5562893, 1996.
20. R.F. Mattrey R. Wrigley G.C. Steinbach E.G. Schutt D.P. Evitts Gas emulsions as ultrasound contrast agents Preliminary results in rabbits and dogs Invest Radiol 29 1994 S139 S141
21. R.S. Meltzer E.G. Tickner R.L. Popp Why do the lungs clear ultrasonic contrast? Ultrasound Med Biol 6 1980 263 269
22. P.M. Morse K.U. Ingard Theoretical Acoustics 1968 McGraw Hill New York
23. PCR Research Chemicals Catalog 1992 PCR Inc Gainesville, FL
24. U. Pison R. Herold S. Schurch The pulmonary surfactant system Biological functions, components, physico-chemical properties and alterations during lung disease Coll Surf A 114 1996 165 184
25. T.R. Porter F. Xie D. Kricsfeld R.W. Armbruster Improved myocardial contrast with second harmonic transient ultrasound response imaging in humans using intravenous perfluorocarbon-exposed sonicated dextrose albumin J Am Coll Clin Cardiol 27 1996 1497 1501
26. Quay SC. Methods for selecting and using gases as ultrasound contrast media. US Patent No. 5,393,524, 1995.
27. Reed TM. Physical chemistry of fluorocarbons. In: Simons JH, ed. Fluorine chemistry, vol. 5. New York: Academic Press, 1964:••–••.
28. R. Schlief Developments in echo-enhancing agents Clin Radiol 51 Suppl 1 1996 5 7
29. Schneider M, Yan F, Grenier P, Puginier J, Barrau, M-B. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for preparation thereof. US Patent No. 5,413,774, 1995.
30. Schutt EA, Evitts DP, Kinner RA, Weers JG, Anderson CD. Stabilized microbubble compositions for ultrasound. US Patent No. 5639443, 1997.
31. Unger EC, Matsunaga T, Ramaswami V, Yellowhair D, Wu G. Methods of preparing gas and gaseous precursor-filled microspheres. International Patent Application No. PCT/US94/05792, 1994.
32. H.D. Van Liew M.E. Burkard Bubbles in circulating blood Stabilization and simulations of cyclic changes of size and content J Appl Physiol 79 1995 1379 1385
33. H.D. Van Liew M.E. Burkard Behavior of bubbles of slowly permeating gas used for ultrasonic imaging contrast Invest Radiol 30 1995 315 321
34. E. Wilhelm R. Battino R.J. Wilcock Low-pressure solubility of gases in liquid water Chem Rev 77 1977 219 262
35. W.-J. Yang Dynamics of gas bubbles in whole blood and plasma J Biomech 4 1971 119 125