Genetic disruption of Abl nuclear import reduces renal apoptosis in a mouse model of cisplatin-induced nephrotoxicity

Cell Death and Differentiation

Volumn 20, Issue 7, 2013, Pages 953-962

  Sridevi, P ^a   Nhiayi, M K ^a   Wang, J Y J ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Nephrotoxicity; p53; Proximal renal tubule cells; PUMA a; Tyrosine kinase

Indexed keywords

ABELSON KINASE; CISPLATIN; IMATINIB; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; EMBRYONIC STEM CELL; FEMALE; FIBROBLAST; GENOTYPE; IMMUNOBLOTTING; KIDNEY PARENCHYMA; KIDNEY PROXIMAL TUBULE; MALE; MOUSE; NEPHROTOXICITY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ANALYSIS; UREA NITROGEN BLOOD LEVEL;

ACUTE KIDNEY INJURY; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BENZAMIDES; CISPLATIN; DISEASE MODELS, ANIMAL; FEMALE; KIDNEY TUBULES, PROXIMAL; MALE; MICE; MICE, KNOCKOUT; MUTATION; NUCLEAR LOCALIZATION SIGNALS; PIPERAZINES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-ABL; PYRIMIDINES; STAT1 TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

MUS;

EID: 84880309528     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.42     Document Type: Article

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