Targeting of the c-Abl Tyrosine Kinase to Mitochondria in the Necrotic Cell Death Response to Oxidative Stress

Journal of Biological Chemistry

Volumn 276, Issue 20, 2001, Pages 17281-17285

  Kumar, Shailendra ^a   Bharti, Ajit ^a   Mishra, Neerad C ^b   Raina, Deepak ^a   Kharbanda, Surender ^a   Saxena, Satya ^b   Kufe, Donald ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; CHEMICAL ACTIVATION; CYTOLOGY; OXIDATION;

NECROTIC CELL DEATH;

ENZYMES;

ABELSON KINASE; ADENOSINE TRIPHOSPHATE; MITOCHONDRIAL PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C DELTA; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; HYBRID PROTEIN; HYDROGEN PEROXIDE; ISOENZYME; PRKCD PROTEIN, HUMAN; PRKCD PROTEIN, MOUSE;

ARTICLE; CELL DEATH; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; GENOTOXICITY; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NECROSIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; ANIMAL; CELL CULTURE; CELL MEMBRANE POTENTIAL; CELL STRAIN U937; DRUG EFFECT; GENETIC TRANSFECTION; INTRACELLULAR MEMBRANE; METABOLISM; MITOCHONDRION; MOUSE; MOUSE MUTANT; ONCOGENE; PHYSIOLOGY;

ANIMALS; CELL DEATH; GENES, ABL; HUMANS; HYDROGEN PEROXIDE; INTRACELLULAR MEMBRANES; ISOENZYMES; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; NECROSIS; OXIDATIVE STRESS; PROTEIN KINASE C; PROTEIN KINASE C-DELTA; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-ABL; REACTIVE OXYGEN SPECIES; RECOMBINANT FUSION PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED; U937 CELLS;

EID: 0035907396     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101414200     Document Type: Article

References (28)

1. Sundaresan, M., Yu, Z.-X., Ferrans, V., Irani, K., and Finkel, T. (1995) Science 270, 296-299
2. Irani, K., Xia, Y., Zweier, J. L., Sollott, S. J., Der, C. J., Fearon, E. R., Sundaresan, M., Finkel, T., and Goldschmidt-Clermont, P. J. (1997) Science 275, 1649-1652
3. Croteau, D., and Bohr, V. (1997) J. Biol. Chem. 272, 25409-25412
4. Berlett, S., and Stadtman, E. (1997) J. Biol. Chem. 272, 20313-20316
5. Li, T., Chen, A., Yu, C., Mao, Y., Wang, H., and Liu, L. (1999) Genes Dev. 13, 1553-1560
6. Migliaccio, E., Giorgio, M., Mele, S., Pelicci, G., Reboldi, P., Pandolfi, P. P., Lanfrancone, L., and Pelicci, P. G. (1999) Nature 402, 309-313
7. Yin, Y., Terauchi, Y., Solomon, G., Aizawa, S., Rangarajan, P., Yazaki, Y., Kadowaki, T., and Barrett, J. (1998) Nature 391, 707-710
8. Johnson, T., Yu, Z., Ferrans, V., Lowenstein, R., and Finkel, T. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 11848-11852
9. Polyak, K., Xia, Y., Zweier, J., Kinzler, K., and Vogelstein, B. (1997) Nature 389, 300-305
10. Kharbanda, S., Ren, R., Pandey, P., Shafman, T. D., Feller, S. M., Weichselbaum, R. R., and Kufe, D. W. (1995) Nature 376, 785-788
11. Yuan, Z. M., Huang, Y., Whang, Y., Sawyers, C., Weichselbaum, R., Kharbanda, S., and Kufe, D. (1996) Nature 382, 272-274
12. Yuan, Z., Huang, Y., Fan, M.-m., Sawers, C., Kharbanda, s., and Kufe, D. (1996) J. Biol. Chem. 271, 26457-26460
13. Yuan, Z. M., Shioya, H., Ishiko, T., Sun, X., Huang, Y., Lu, H., Kharbanda, S., Weichselbaum, R., and Kufe, D. (1999) Nature 399, 814-817
14. Gong, J., Costanzo, A., Yang, H., Melino, G., Kaelin JR, W., Levrero, M., and Wang, J. Y. J. (1999) Nature 399, 806-809
15. Agami, R., Blandino, G., Oren, M., and Shaul, Y. (1999) Nature 399, 809-813
16. Kharbanda, S., Pandey, P., Ren, R., Feller, S., Mayer, B., Zon, L., and Kufe, D. (1995) J. Biol. Chem. 270, 30278-30281
17. Pandey, P., Raingeaud, J., Kaneki, M., Weichselbaum, R., Davis, R., Kufe, D., and Kharbanda, S. (1996) J. Biol. Chem. 271, 23775-23779
18. Kharbanda, S., Pandey, P., Yamauchi, T., Kumar, S., Kaneki, M., Kumar, V., Bharti, A., Yuan, Z., Ghanem, L., Rana, A., Weichselbaum, R., Johnson, G., and Kufe, D. (2000) Mol. Cell. Biol. 20, 4979-4989
19. Sun, X., Majumder, P., Shioya, H., Wu, F., Kumar, S., Weichselbaum, R., Kharbanda, S., and Kufe, D. (2000) J. Biol. Chem. 275, 17237-17240
20. Sun, X., Wu, F., Datta, R., Kharbanda, S., and Kufe, D. (2000) J. Biol. Chem. 275, 7470-7473
21. Tybulewicz, V. L. J., Crawford, C. E., Jackson, P. K., Bronson, R. T., and Mulligan, R. C. (1991) Cell 65, 1153-1163
22. Roederer, M., Staal, F. J., Raju, P. A., Ela, S. W., and Herzenberg, L. A. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 4884-4888
23. Staal, F. J., Roederer, M., Herzenberg, L. A. and Herzenberg, L. A. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 9943-9947
24. Gschwendt, M., Kielbassa, K., Kittstein, W., and Marks, F. (1994) FEBS Lett. 347, 773-779
25. Zamzami, N., Marchetti, P., Castedo, M., Decaudin, D., Macho, A., Hirsch, T., Susin, S. A., Petit, P. X., Mignotte, B., and Kroemer, G. (1995) J. Exp. Med. 182, 367-377
26. Leist, M., Single, B., Castoldi, A. F., Kuhnle, S., and Nicotera, P. (1997) J. Exp. Med. 185, 1481-1486
27. Nicotera, P., Leist, M., and Ferrando-May, E. (1998) Toxicology Letters 102-103, 139-142
28. Ha, H. C., and Snyder, S. H. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 13978-13982