Survival and differentiation defects contribute to neutropenia in glucose-6-phosphatase-β (G6PC3) deficiency in a model of mouse neutrophil granulocyte differentiation

Cell Death and Differentiation

Volumn 20, Issue 8, 2013, Pages 1068-1079

  Gautam, S ^a,b   Kirschnek, S ^a   Gentle, I E ^a   Kopiniok, C ^a   Henneke, P ^a   Hacker H ^c   Malleret, L ^d   Belaaouaj, A ^d   Hacker G ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d REIMS UNIVERSITY HOSPITAL   (France)

Author keywords

Apoptosis; Differentiation; Neutropenia

Indexed keywords

BIM PROTEIN; CD11B ANTIGEN; GLUCOSE 6 PHOSPHATASE; GLUCOSE 6 PHOSPHATASE BETA; INTERLEUKIN 6; LEUKOCYTE ELASTASE; PROTEIN BAX; PROTEIN BCL XL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; EFFECTOR CELL; ENDOPLASMIC RETICULUM STRESS; FLOW CYTOMETRY; GLUCOSE METABOLISM; GLUCOSE UTILIZATION; GLYCOSYLATION; IN VIVO STUDY; MACROPHAGE; MOUSE; NEUTROPENIA; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; PROMYELOCYTE; PROTEIN EXPRESSION; STEM CELL; UPREGULATION; WILD TYPE;

ANIMALS; APOPTOSIS; BCL-X PROTEIN; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; ENDOPLASMIC RETICULUM STRESS; GLUCOSE; GLUCOSE-6-PHOSPHATASE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, ANIMAL; NEUTROPENIA; NEUTROPHILS;

MUS;

EID: 84880306733     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.39     Document Type: Article

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