Deletion of the gene encoding the ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein (UGRP)/glucose-6- phosphatase catalytic subunit-β results in lowered plasma cholesterol and elevated glucagon

Journal of Biological Chemistry

Volumn 281, Issue 52, 2006, Pages 39982-39989

  Wang, Yingda ^a   Oeser, James K ^a   Yang, Chunmei ^b   Sarkar, Suparna ^c   Hackl, Seija I ^c   Hasty, Alyssa H ^a   McGuinness, Owen P ^a   Paradee, William ^b   Hutton, John C ^c   Powell, David R ^b   O'Brien, Richard M ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LEXICON PHARMACEUTICALS INC   (United States)

^c UNIVERSITY OF COLORADO DENVER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE HOMEOSTASIS; GLYCOGEN STORAGE DISEASE (GSD); PLASMA CHOLESTEROL;

BIOCHEMISTRY; CATALYSIS; CHOLESTEROL; HYDROLYSIS; PROTEINS;

GENETIC ENGINEERING;

CHOLESTEROL; GLUCAGON; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLUCOSE 6 PHOSPHATASE BETA; PROTEIN SUBUNIT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE DELETION; GENE EXPRESSION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLYCOGEN LIVER LEVEL; GLYCOGEN STORAGE DISEASE TYPE 1; GLYCOGENOLYSIS; GROWTH RETARDATION; HUMAN; HYDROLYSIS; HYPERCHOLESTEROLEMIA; HYPERTRIGLYCERIDEMIA; HYPOGLYCEMIA; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; CATALYTIC DOMAIN; CHOLESTEROL; DOWN-REGULATION; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; GLUCAGON; GLUCOSE; GLUCOSE-6-PHOSPHATASE; GLYCOGEN STORAGE DISEASE TYPE I; HOMEOSTASIS; ISOENZYMES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN SUBUNITS; PROTEINS; UP-REGULATION;

EID: 33845993648     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M605858200     Document Type: Article

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