Glucose-6-phosphatase-(3, implicated in a congenital neutropenia syndrome, is essential for macrophage energy homeostasis and functionality

Blood

Volumn 119, Issue 17, 2012, Pages 4047-4055

  Jun, Hyun Sik ^a   Cheung, YukYin ^a   Lee, Young Mok ^a   Mansfield, Brian C ^a   Chou, Janice Y ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE 6 PHOSPHATASE; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CHEMOTAXIS; CONTROLLED STUDY; DOWN REGULATION; ENERGY; FEMALE; FERTILITY; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HOMEOSTASIS; HUMAN; IMMUNE DEFICIENCY; IN VIVO STUDY; INFLAMMATION; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PHAGOCYTE; PREGNANCY; PRIORITY JOURNAL; RESPIRATORY BURST; SEVERE CONGENITAL NEUTROPENIA; UTERUS;

EID: 84860336487     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-09-377820     Document Type: Article

References (46)

1. Chou JY, Jun HS, Mansfield BC. Glycogen storage disease type I and G6Pase-beta deficiency: etiology and therapy. Nat Rev Endocrinol. 2010; 6(12):676-688.
2. Boztug K, Appaswamy G, Ashikov A, et al. Asyndrome with congenital neutropenia and mutations in G6PC3. N Engl J Med. 2009; 360(1):32-43.
3. McDermott DH, DeRavin SS, Jun HS, et al. Severe congenital neutropenia due to G6PC3 deficiency with increased neutrophil CXCR4 expression and myelokathexis. Blood. 2010; 116(15): 2793-2802.
4. Banka S, Chervinsky E, Newman WG, et al. Further delineation of the phenotype of severe congenital neutropenia type 4 due to mutations in G6PC3. Eur J Hum Genet. 2011; 19(1):18-22.
5. Shieh J-J, Pan C-J, Mansfield BC, Chou JY. Glucose-6-phosphate hydrolase, widely expressed outside the liver, can explain age-dependent resolution of hypoglycemia in glycogen storage disease type Ia. J Biol Chem. 2003; 278(47):47098-47103. (Pubitemid 37452295)
6. Ghosh A, Shieh J-J, Pan C-J, Chou JY. Histidine-167 is the phosphate acceptor in glucose-6-phosphatase-beta forming a phosphohistidine-enzyme intermediate during catalysis. J Biol Chem. 2004; 279(13):12479-12483. (Pubitemid 38445817)
7. Cheung YY, Kim SY, Yiu WH, et al. Impaired neutrophil activity and increased susceptibility to bacterial infection in mice lacking glucose-6-phosphatase-beta. J Clin Invest. 2007; 117(3): 784-793.
8. Jun HS, Lee YM, McDermott DH, et al. Lack of glucose recycling between endoplasmic reticulum and cytoplasm underlies cellular dysfunction in glucose-6-phosphatase-beta-deficient neutrophils in a congenital neutropenia syndrome. Blood. 2010; 116(15):2783-2792.
9. Chou JY, Matern D, Mansfield BC, Chen Y-T. Type I glycogen storage diseases: disorders of the glucose-6-phosphatase complex. Curr Mol Med. 2002; 2(2):121-143. (Pubitemid 34649836)
10. Chou JY, Jun HS, Mansfield BC. Neutropenia in type Ib glycogen storage disease. Curr Opin Hematol. 2010; 17(1):36-42.
11. Lei K-J, Shelly LL, Pan C-J, Sidbury JB, Chou JY. Mutations in the glucose-6-phosphatase gene that cause glycogen storage disease type 1a. Science. 1993; 262(5133):580-583. (Pubitemid 23350674)
12. Kilpatrick L, Garty BZ, Lundquist KF, et al. Impaired metabolic function and signaling defects in phagocytic cells in glycogen storage disease type 1b. J Clin Invest. 1990; 86(1):196-202. (Pubitemid 20226992)
13. McCawley LJ McCawley LJ, Korchak HM, et al. Interferon-gamma corrects the respiratory burst defect in vitro in monocyte-derived macrophages from glycogen storage disease type 1b patients. Pediatr Res. 1993; 34(3):265-269. (Pubitemid 23254540)
14. Gonzalez-Mejia ME, Doseff AI. Regulation of monocytes and macrophages cell fate. Front Bio. sci. 2009; 14:2413-2431.
15. Valledor AF, Comalada M, Santamaría-Babi LF, Lloberas J, Celada A. Macrophage proinflammatory activation and deactivation: a question of balance. Adv Immunol. 2010; 108:1-20.
16. Straszewski-Chavez SL, Abrahams VM, Mor G. The role of apoptosis in the regulation of trophoblast survival and differentiation during pregnancy. Endocr Rev. 2005; 26(7):877-997.
17. Renaud SJ, Graham CH. The role of macro-phages in utero-placental interactions during normal and pathological pregnancy. Immunol Invest. 2008; 37(5):535-564.
18. Nagamatsu T, Schust DJ. The immunomodulatory roles of macrophages at the maternal-fetal interface. Reprod Sci. 2010; 17(3):209-218.
19. Singh RK, Gupta S, Dastidar S, Ray A. Cysteinyl leukotrienes and their receptors: molecular and functional characteristics. Pharmacology. 2010; 85(6):336-349.
20. Wan CP, Park CS, Lau BH.A rapid and simple microfluorometric phagocytosis assay. J Immunol Methods. 1993; 162(1):1-7.
21. Lee MJ, Park JY, Lee SY, et al. Modulation of constitutive and delayed apoptosis by brefeldin A in human neutrophils. Int Immunopharmacol. 2003; 3(6):835-843.
22. Lin H-Y, Masso-Welch P, Di Y-P, et al. The 170-kDa glucose-regulated stress protein is an endoplasmic reticulum protein that binds immunoglobulin. Mol Biol Cell. 1993; 4(11):1109-1119. (Pubitemid 24007574)
23. Stein O, Dabach Y, Ben-Naim M, et al. Lower macrophage recruitment and atherosclerosis resistance in FVB mice. Atherosclerosis. 2006; 189(2):336-341. (Pubitemid 44634498)
24. Lu B, Rutledge BJ, Gu L, et al. Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J Exp Med. 1998; 187(4):601-608. (Pubitemid 28093362)
25. Deshmane SL, Kremlev S, Amini S, Sawaya BE. Monocyte chemoattractant protein-1 (MCP-1): an overview. J Interferon Cytokine Res. 2009; 29(6): 313-326.
26. Barreda DR, Hanington PC, Belosevic M. Regulation of myeloid development and function by colony stimulating factors. Dev Comp Immunol. 2004; 28(5):509-554. (Pubitemid 38177451)
27. Visser CE, Tekstra J, Brouwer-Steenbergen JJ, et al. Chemokines produced by mesothelial cells: huGRO-alpha, IP-10, MCP-1 and RANTES. Clin Exp Immunol. 1998; 112(2):270-275. (Pubitemid 28266686)
28. Witowski J, Thiel A, Dechend R, et al. Synthesis of C-X-C and C-C chemokines by human peritoneal fibroblasts: induction by macrophagederived cytokines. Am J Pathol. 2001; 158(4): 1441-1450. (Pubitemid 32281308)
29. Lanfrancone L, Boraschi D, Ghiara P, et al. Human peritoneal mesothelial cells produce many cytokines (granulocyte colony-stimulating factor [CSF], granulocyte-monocyte-CSF, macro-phage-CSF, interleukin-1 [IL-1], and IL-6) and are activated and stimulated to grow by IL-1. Blood. 1992; 80(11):2835-2842.
30. Colotta F, Borré A, Wang JM, et al. Expression of a monocyte chemotactic cytokine by human mononuclear phagocytes. J Immunol. 1992; 148(3):760-765.
31. Nathan CF. Secretory products of macrophages. J Clin Invest. 1987; 79(2):319-26. (Pubitemid 17009661)
32. Schroder M, Kaufman RJ. The mammalian unfolded protein response. Annu Rev Biochem. 2005; 74:739-789. (Pubitemid 40995523)
33. Perlman H, Pagliari LJ, Georganas C, et al. FLICE-inhibitory protein expression during macrophage differentiation confers resistance to fasmediated apoptosis. J Exp Med. 1999; 190(11): 1679-1688. (Pubitemid 30002349)
34. Liu H, Perlman H, Pagliari LJ, et al. Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages. Role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation. J Exp Med. 2001; 194(2):113-126.
35. Siegel RM. Caspases at the crossroads of immune-cell life and death. Nat Rev Immunol. 2006; 6(4):308-317.
36. Calder PC, Dimitriadis G, Newsholme P. Glucose metabolism in lymphoid and inflammatory cells and tissues. Curr Opin Clin Nutr Metab Care. 2007; 10(4):531-540. (Pubitemid 46934126)
37. Forman HJ, Torres M. Redox signaling in macro-phages. Mol Aspects Med. 2001; 22(4-5):189-216.
38. Babior BM. NADPH oxidase. Curr Opin Immunol. 2004; 16(1):42-47. (Pubitemid 38198116)
39. El-Benna J, Dang PM, Gougerot-Pocidalo MA. Priming of the neutrophil NADPH oxidase activation: role of p47phox phosphorylation and NOX2 mobilization to the plasma membrane. Semin Immunopathol. 2008; 30(3):279-289.
40. Wood GW, Hausmann E, Choudhuri R. Relative role of CSF-1, MCP-1/JE, and RANTES in macrophage recruitment during successful pregnancy. Mol Reprod Dev. 1997; 46(1):62-69.
41. Wood GW, Hausmann EH, Kanakaraj K. Expression and regulation of chemokine genes in the mouse uterus during pregnancy. Cytokine. 1999; 11(12):1038-1045. (Pubitemid 30045343)
42. Medina RA, Southworth R, Fuller W, Garlick PB. Lactate-induced translocation of GLUT1 and GLUT4 is not mediated by the phosphatidyl-inositol-3- kinase pathway in the rat heart. Basic Res Cardiol. 2002; 97(2):168-176. (Pubitemid 34223508)
43. Kim MS, Lee J, Ha J, et al. ATP stimulates glucose transport through activation of P2 purinergic receptors in C2C12 skeletal muscle cells. Arch Biochem Biophys. 2002; 401(2):205-214. (Pubitemid 34848623)
44. Salamonsen LA, Dimitriadis E, Robb L. Cytokines in implantation. Semin Reprod Med. 2000; 18(3): 299-310. (Pubitemid 32240061)
45. Bartocci A, Pollard JW, Stanley ER. Regulation of colony-stimulating factor 1 during pregnancy. J Exp Med. 1986; 164(3):956-961. (Pubitemid 16024849)
46. Pollard JW, Hunt JS, Wiktor-Jedrzejczak W, et al. A pregnancy defect in the osteopetrotic (op/op) mouse demonstrates the requirement for CSF-1 in female fertility. Dev Biol. 1991; 148(1):273-283. (Pubitemid 121004766)