Rac1 signaling regulates sepsis-induced pathologic inflammation in the lung via attenuation of Mac-1 expression and CXC chemokine formation

Journal of Surgical Research

Volumn 183, Issue 2, 2013, Pages 798-807

  Hwaiz, Rundk ^a   Hasan, Zirak ^a   Rahman, Milladur ^a   Zhang, Su ^a   Palani, Karzan ^a   Syk, Ingvar ^a   Jeppsson, Bengt ^a   Thorlacius, Henrik ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Adhesion; Inflammation; Leukocytes; Migration and platelets

Indexed keywords

4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; ALPHA CHEMOKINE; CD11B ANTIGEN; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 6; RAC1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; GENE EXPRESSION; IN VITRO STUDY; LUNG EDEMA; LUNG INFECTION; LUNG INJURY; LUNG LAVAGE; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADHESION; INFLAMMATION; LEUKOCYTES; MIGRATION AND PLATELETS;

AMINOQUINOLINES; ANIMALS; CECUM; CELL MOVEMENT; CHEMOKINES, CXC; DISEASE MODELS, ANIMAL; HMGB1 PROTEIN; LIGATION; MACROPHAGE-1 ANTIGEN; MALE; MICE; MICE, INBRED C57BL; NEUROPEPTIDES; NEUTROPHILS; PNEUMONIA; PUNCTURES; PYRIMIDINES; RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN; SEPSIS; SIGNAL TRANSDUCTION;

EID: 84880299117     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.02.045     Document Type: Article

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