Helper-dependent adenoviral liver gene therapy protects against induced attacks and corrects protein folding stress in acute intermittent porphyria mice

Human Molecular Genetics

Volumn 22, Issue 14, 2013, Pages 2929-2940

  Unzu, Carmen ^a   Sampedro, Ana ^a   Mauleón, Itsaso ^a   González Aparicio, Manuela ^a   De Salamanca, Rafael Enríquez ^b   Prieto, Jesús ^a   Aragón, Tomás ^a   Fontanellas, Antonio ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CHAPERONE; HELPER DEPENDENT ADENOVIRUS VECTOR; PORPHOBILINOGEN DEAMINASE; UNCLASSIFIED DRUG;

ACUTE INTERMITTENT PORPHYRIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELL ORGANELLE; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; DOSE RESPONSE; DRUG EFFICACY; ENDOPLASMIC RETICULUM; FEMALE; GENE EXPRESSION; HOMEOSTASIS; LIVER CELL; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; VIRAL GENE THERAPY;

ADENOVIRIDAE; ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; GENETIC THERAPY; GENETIC VECTORS; HEPATOCYTES; HUMANS; HYDROXYMETHYLBILANE SYNTHASE; LIVER; MALE; MICE; MICE, INBRED C57BL; PORPHYRIA, ACUTE INTERMITTENT; PROTEIN FOLDING;

EID: 84880276950     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt148     Document Type: Article

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