-
1
-
-
35349016429
-
Antigen-induced regulatory T cells in HBV chronically infected patients
-
Barboza, L., S. Salmen, L. Goncalves, M. Colmenares, D. Peterson, H. Montes, R. Cartagirone, M. C. Gutierrez, and L. Berrueta. 2007. Antigen-induced regulatory T cells in HBV chronically infected patients. Virology 368:41-49.
-
(2007)
Virology
, vol.368
, pp. 41-49
-
-
Barboza, L.1
Salmen, S.2
Goncalves, L.3
Colmenares, M.4
Peterson, D.5
Montes, H.6
Cartagirone, R.7
Gutierrez, M.C.8
Berrueta, L.9
-
2
-
-
20844440410
-
IFN-alpha gene therapy for woodchuck hepatitis with adeno-associated virus: Differences in duration of gene expression and antiviral activity using intra-portal or intramuscular routes
-
Berraondo, P., L. Ochoa, J. Crettaz, F. Rotellar, A. Vales, E. Martinez-Anso, M. Zaratiegui, J. Ruiz, G. Gonzalez-Aseguinolaza, and J. Prieto. 2005. IFN-alpha gene therapy for woodchuck hepatitis with adeno-associated virus: differences in duration of gene expression and antiviral activity using intra-portal or intramuscular routes. Mol. Ther. 12:68-76.
-
(2005)
Mol. Ther
, vol.12
, pp. 68-76
-
-
Berraondo, P.1
Ochoa, L.2
Crettaz, J.3
Rotellar, F.4
Vales, A.5
Martinez-Anso, E.6
Zaratiegui, M.7
Ruiz, J.8
Gonzalez-Aseguinolaza, G.9
Prieto, J.10
-
3
-
-
33744808242
-
The immune response during hepatitis B virus infection
-
Bertoletti, A., and A. J. Gehring. 2006. The immune response during hepatitis B virus infection. J. Gen. Virol. 87:1439-1449.
-
(2006)
J. Gen. Virol
, vol.87
, pp. 1439-1449
-
-
Bertoletti, A.1
Gehring, A.J.2
-
4
-
-
0032169470
-
Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B
-
Boni, C., A. Bertoletti, A. Penna, A. Cavalli, M. Pilli, S. Urbani, P. Scog-namiglio, R. Boehme, R. Panebianco, F. Fiaccadori, and C. Ferrari. 1998. Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B. J. Clin. Investig. 102:968-975.
-
(1998)
J. Clin. Investig
, vol.102
, pp. 968-975
-
-
Boni, C.1
Bertoletti, A.2
Penna, A.3
Cavalli, A.4
Pilli, M.5
Urbani, S.6
Scog-namiglio, P.7
Boehme, R.8
Panebianco, R.9
Fiaccadori, F.10
Ferrari, C.11
-
5
-
-
34247117935
-
Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection
-
Boni, C., P. Fisicaro, C. Valdatta, B. Amadei, P. Di Vincenzo, T. Giuberti, D. Laccabue, A. Zerbini, A. Cavalli, G. Missale, A. Bertoletti, and C. Ferrari. 2007. Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection. J. Virol. 81:4215-4225.
-
(2007)
J. Virol
, vol.81
, pp. 4215-4225
-
-
Boni, C.1
Fisicaro, P.2
Valdatta, C.3
Amadei, B.4
Di Vincenzo, P.5
Giuberti, T.6
Laccabue, D.7
Zerbini, A.8
Cavalli, A.9
Missale, G.10
Bertoletti, A.11
Ferrari, C.12
-
6
-
-
17744383748
-
Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B: New perspectives for immune therapy
-
Boni, C., A Penna, G. S. Ogg, A. Bertoletti, M. Pilli, C. Cavallo, A. Cavalli, S. Urbani, R. Boehme, R. Panebianco, F. Fiaccadori, and C. Ferrari. 2001. Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B: new perspectives for immune therapy. Hepatology 33:963-971.
-
(2001)
Hepatology
, vol.33
, pp. 963-971
-
-
Boni, C.1
Penna, A.2
Ogg, G.S.3
Bertoletti, A.4
Pilli, M.5
Cavallo, C.6
Cavalli, A.7
Urbani, S.8
Boehme, R.9
Panebianco, R.10
Fiaccadori, F.11
Ferrari, C.12
-
7
-
-
0033951496
-
A phase I/II study of recombinant human interleukin-12 in patients with chronic hepatitis B
-
Carreno, V., S. Zeuzem, U. Hopf, P. Marcellin, W. G. Cooksley, J. Fevery, M. Diago, R. Reddy, M. Peters, K. Rittweger, A. Rakhit, and M. Pardo. 2000. A phase I/II study of recombinant human interleukin-12 in patients with chronic hepatitis B. J. Hepatol. 32:317-324.
-
(2000)
J. Hepatol
, vol.32
, pp. 317-324
-
-
Carreno, V.1
Zeuzem, S.2
Hopf, U.3
Marcellin, P.4
Cooksley, W.G.5
Fevery, J.6
Diago, M.7
Reddy, R.8
Peters, M.9
Rittweger, K.10
Rakhit, A.11
Pardo, M.12
-
8
-
-
0030997139
-
Interleukin-12 inhibits hepatitis B virus replication in transgenic mice
-
Cavanaugh, V. J., L. G. Guidotti, and F. V. Chisari. 1997. Interleukin-12 inhibits hepatitis B virus replication in transgenic mice. J. Virol. 71:3236-3243.
-
(1997)
J. Virol
, vol.71
, pp. 3236-3243
-
-
Cavanaugh, V.J.1
Guidotti, L.G.2
Chisari, F.V.3
-
9
-
-
33748943615
-
Intrahepatic injection of adenovirus reduces inflammation and increases gene transfer and therapeutic effect in mice
-
Crettaz, J., P. Berraondo, I. Mauleon, L. Ochoa, V. Shankar, M. Barajas, N. van Rooijen, S. Kochanek, C. Qian, J. Prieto, R. Hernández-Alcoceba, and G. Gonzalez-Aseguinolaza. 2006. Intrahepatic injection of adenovirus reduces inflammation and increases gene transfer and therapeutic effect in mice. Hepatology 44:623-632.
-
(2006)
Hepatology
, vol.44
, pp. 623-632
-
-
Crettaz, J.1
Berraondo, P.2
Mauleon, I.3
Ochoa, L.4
Shankar, V.5
Barajas, M.6
van Rooijen, N.7
Kochanek, S.8
Qian, C.9
Prieto, J.10
Hernández-Alcoceba, R.11
Gonzalez-Aseguinolaza, G.12
-
11
-
-
0033617583
-
Viral clearance without destruction of infected cells during acute HBV infection
-
Guidotti, L. G., R. Rochford, J. Chung, M. Shapiro, R. Purcell, and F. V. Chisari. 1999. Viral clearance without destruction of infected cells during acute HBV infection. Science 284:825-829.
-
(1999)
Science
, vol.284
, pp. 825-829
-
-
Guidotti, L.G.1
Rochford, R.2
Chung, J.3
Shapiro, M.4
Purcell, R.5
Chisari, F.V.6
-
12
-
-
47049114816
-
Aberrant lymphocyte activation precedes delayed virus-specific T-cell response after both primary infection and secondary exposure to hepadnaviras in the woodchuck model of hepatitis B virus infection
-
Gujar, S. A., A. K. Jenkins, C. S. Guy, J. Wang, and T. I. Michalak. 2008. Aberrant lymphocyte activation precedes delayed virus-specific T-cell response after both primary infection and secondary exposure to hepadnaviras in the woodchuck model of hepatitis B virus infection. J. Virol. 82:6992-7008.
-
(2008)
J. Virol
, vol.82
, pp. 6992-7008
-
-
Gujar, S.A.1
Jenkins, A.K.2
Guy, C.S.3
Wang, J.4
Michalak, T.I.5
-
14
-
-
0036268305
-
Long-term transgene expression in the RPE after gene transfer with a high-capacity adenoviral vector
-
Kreppel, F., T. T. Luther, I. Semkova, U. Schraermeyer, and S. Kochanek. 2002. Long-term transgene expression in the RPE after gene transfer with a high-capacity adenoviral vector. Investig. Ophthalmol. Vis. Sci. 43:1965-1970.
-
(2002)
Investig. Ophthalmol. Vis. Sci
, vol.43
, pp. 1965-1970
-
-
Kreppel, F.1
Luther, T.T.2
Semkova, I.3
Schraermeyer, U.4
Kochanek, S.5
-
15
-
-
0036378341
-
Reduced virus specific T helper cell induction by autologous dendritic cells in patients with chronic hepatitis B-restoration by exogenous interleukin-12
-
Lohr, H. F., S. Pingel, W. O. Bocher, H. Bernhard, S. Herzog-Hauff, S. Rose-John, and P. R. Galle. 2002. Reduced virus specific T helper cell induction by autologous dendritic cells in patients with chronic hepatitis B-restoration by exogenous interleukin-12. Clin. Exp. Immunol. 130:107-114.
-
(2002)
Clin. Exp. Immunol
, vol.130
, pp. 107-114
-
-
Lohr, H.F.1
Pingel, S.2
Bocher, W.O.3
Bernhard, H.4
Herzog-Hauff, S.5
Rose-John, S.6
Galle, P.R.7
-
16
-
-
34247268523
-
Navigating the maze of hepatitis B treatments
-
Lok, A. S. 2007. Navigating the maze of hepatitis B treatments. Gastroen-terology 132:1586-1594.
-
(2007)
Gastroen-terology
, vol.132
, pp. 1586-1594
-
-
Lok, A.S.1
-
17
-
-
33847406557
-
PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver
-
Maier, H., M. Isogawa, G. J. Freeman, and F. V. Chisari. 2007. PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver. J. Immunol. 178:2714- 2720.
-
(2007)
J. Immunol
, vol.178
, pp. 2714-2720
-
-
Maier, H.1
Isogawa, M.2
Freeman, G.J.3
Chisari, F.V.4
-
18
-
-
33846534236
-
The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infection
-
Menne, S., and P. J. Cote. 2007. The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infection. World J. Gastroenterology 13:104-124.
-
(2007)
World J. Gastroenterology
, vol.13
, pp. 104-124
-
-
Menne, S.1
Cote, P.J.2
-
19
-
-
64249142159
-
Chemo-immu-notherapy of chronic hepatitis B virus infection in the woodchuck model breaks immunologic tolerance and restores T-cell responses to PreS and S regions of the viral envelope protein
-
Menne, S., B. C. Tennant, J. L. Gerin, and P. J. Cote. 2007. Chemo-immu-notherapy of chronic hepatitis B virus infection in the woodchuck model breaks immunologic tolerance and restores T-cell responses to PreS and S regions of the viral envelope protein. J. Virol. 51:3177-3184.
-
(2007)
J. Virol
, vol.51
, pp. 3177-3184
-
-
Menne, S.1
Tennant, B.C.2
Gerin, J.L.3
Cote, P.J.4
-
20
-
-
0033054559
-
Down-regulation of the pharmacokinetic-pharmacody-namic response to interleukin-12 during long-term administration to patients with renal cell carcinoma and evaluation of the mechanism of this "adaptive response" in mice
-
Rakhit, A., M. M. Yeon, J. Ferrante, S. Fettner, R. Nadeau, R. Motzer, R. Bukowski, D. M. Carvajal, V. L. Wilkinson, D. H. Presky, J. Magram, and M. K. Gately. 1999. Down-regulation of the pharmacokinetic-pharmacody-namic response to interleukin-12 during long-term administration to patients with renal cell carcinoma and evaluation of the mechanism of this "adaptive response" in mice. Clin. Pharmacol. Ther. 65:615-629.
-
(1999)
Clin. Pharmacol. Ther
, vol.65
, pp. 615-629
-
-
Rakhit, A.1
Yeon, M.M.2
Ferrante, J.3
Fettner, S.4
Nadeau, R.5
Motzer, R.6
Bukowski, R.7
Carvajal, D.M.8
Wilkinson, V.L.9
Presky, D.H.10
Magram, J.11
Gately, M.K.12
-
21
-
-
30944449094
-
Lamivudine plus interleukin-12 combination therapy in chronic hepatitis B: Antiviral and immunological activity
-
Rigopoulou, E. I., D. Suri, S. Chokshi, I. Mullerova, S. Rice, R. S. Tedder, R. Williams, and N. V. Naoumov. 2005. Lamivudine plus interleukin-12 combination therapy in chronic hepatitis B: antiviral and immunological activity. Hepatology 42:1028-1036.
-
(2005)
Hepatology
, vol.42
, pp. 1028-1036
-
-
Rigopoulou, E.I.1
Suri, D.2
Chokshi, S.3
Mullerova, I.4
Rice, S.5
Tedder, R.S.6
Williams, R.7
Naoumov, N.V.8
-
22
-
-
0030959049
-
Interleukin-12 induction of Thl cytokines is important for viral clearance in chronic hepatitis B
-
Rossol, S., G. Marinos, P. Carucci, M. V. Singer, R. Williams, and N. V. Naoumov. 1997. Interleukin-12 induction of Thl cytokines is important for viral clearance in chronic hepatitis B. J. Clin. Investig. 99:3025-3033.
-
(1997)
J. Clin. Investig
, vol.99
, pp. 3025-3033
-
-
Rossol, S.1
Marinos, G.2
Carucci, P.3
Singer, M.V.4
Williams, R.5
Naoumov, N.V.6
-
24
-
-
0032992117
-
The presence of high amounts of HBV-DNA in serum is associated with suppressed costimulatory effects of interleukin 12 on HBV-induced immune response
-
Schlaak, J. F., G. Tully, H. F. Lohr, G. Gerken, and K. H. Meyer zum Biischenfelde. 1999. The presence of high amounts of HBV-DNA in serum is associated with suppressed costimulatory effects of interleukin 12 on HBV-induced immune response. J. Hepatol. 30:353-358.
-
(1999)
J. Hepatol
, vol.30
, pp. 353-358
-
-
Schlaak, J.F.1
Tully, G.2
Lohr, H.F.3
Gerken, G.4
Meyer zum Biischenfelde, K.H.5
-
25
-
-
1842735646
-
Quantitation of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) in the liver of HBV-infected patients by LightCycler real-time PCR
-
Singh, M, A. Dicaire, A. E. Wakil, C. Luscombe, and S. L. Sacks. 2004. Quantitation of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) in the liver of HBV-infected patients by LightCycler real-time PCR. J. Virol. Methods 118:159-167.
-
(2004)
J. Virol. Methods
, vol.118
, pp. 159-167
-
-
Singh, M.1
Dicaire, A.2
Wakil, A.E.3
Luscombe, C.4
Sacks, S.L.5
-
26
-
-
16244385911
-
Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection
-
Stoop, J. N., R. G. van der Molen, C. C. Baan, L. J. van der Laan, E. J. Kuipers, J. G. Kusters, and H. L. Janssen. 2005. Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection. Hepatology 41:771-778.
-
(2005)
Hepatology
, vol.41
, pp. 771-778
-
-
Stoop, J.N.1
van der Molen, R.G.2
Baan, C.C.3
van der Laan, L.J.4
Kuipers, E.J.5
Kusters, J.G.6
Janssen, H.L.7
-
27
-
-
34047266620
-
Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B
-
Stoop, J. N., R. G. van der Molen, E. J. Kuipers, J. G. Kusters, and H. L. Janssen. 2007. Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B. Virology 361:141-148.
-
(2007)
Virology
, vol.361
, pp. 141-148
-
-
Stoop, J.N.1
van der Molen, R.G.2
Kuipers, E.J.3
Kusters, J.G.4
Janssen, H.L.5
-
28
-
-
4644351630
-
Cytotoxic T-lymphocyte antigen 4 gene and recovery from hepatitis B virus infection
-
Thio, C. L., T. L. Mosbruger, R. A. Kaslow, C. L. Karp, S. A. Strathdee, D. Vlahov, S. J. O'Brien, J. Astemborski, and D. L. Thomas. 2004. Cytotoxic T-lymphocyte antigen 4 gene and recovery from hepatitis B virus infection. J. Virol. 78:11258-11262.
-
(2004)
J. Virol
, vol.78
, pp. 11258-11262
-
-
Thio, C.L.1
Mosbruger, T.L.2
Kaslow, R.A.3
Karp, C.L.4
Strathdee, S.A.5
Vlahov, D.6
O'Brien, S.J.7
Astemborski, J.8
Thomas, D.L.9
-
29
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri, G. 2003. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3:133-146.
-
(2003)
Nat. Rev. Immunol
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
30
-
-
0347991866
-
Prolonged and induc-ible transgene expression in the liver using gutless adenovirus: A potential therapy for liver cancer
-
Wang, L., R. Hernandez-Alcoceba, V. Shankar, M. Zabala, S. Kochanek, B. Sangro, M. G. Kramer, J. Prieto, and C. Qian. 2004. Prolonged and induc-ible transgene expression in the liver using gutless adenovirus: a potential therapy for liver cancer. Gastroenterology 126:278-289.
-
(2004)
Gastroenterology
, vol.126
, pp. 278-289
-
-
Wang, L.1
Hernandez-Alcoceba, R.2
Shankar, V.3
Zabala, M.4
Kochanek, S.5
Sangro, B.6
Kramer, M.G.7
Prieto, J.8
Qian, C.9
-
31
-
-
33947397924
-
IL-12 promotes HBV-specific central memory CD8+ T cell responses by PBMCs from chronic hepatitis B virus carriers
-
Xiong, S. Q., B. L. Lin, X. Gao, H. Tang, and C. Y. Wu. 2007. IL-12 promotes HBV-specific central memory CD8+ T cell responses by PBMCs from chronic hepatitis B virus carriers. Int. Immunopharmacol. 7:578-587.
-
(2007)
Int. Immunopharmacol
, vol.7
, pp. 578-587
-
-
Xiong, S.Q.1
Lin, B.L.2
Gao, X.3
Tang, H.4
Wu, C.Y.5
-
32
-
-
33947699267
-
Molecular mechanisms of resistance to antiviral therapy in patients with chronic hepatitis B
-
Yuan, H. J., and W. M. Lee. 2007. Molecular mechanisms of resistance to antiviral therapy in patients with chronic hepatitis B. Curr. Mol. Med. 7:185-197.
-
(2007)
Curr. Mol. Med
, vol.7
, pp. 185-197
-
-
Yuan, H.J.1
Lee, W.M.2
-
33
-
-
0034467888
-
Combination therapy with lamivudine and adenovirus causes transient suppression of chronic woodchuck hepatitis virus infections
-
Zhou, T., J. T. Guo, F. A. Nunes, K. L. Molnar-Kimber, J. M. Wilson, C. E. Aldrich, J. Saputelli, S. Litwin, L. D. Condreay, C. Seeger, and W.S. Mason. 2000. Combination therapy with lamivudine and adenovirus causes transient suppression of chronic woodchuck hepatitis virus infections. J. Virol. 74: 11754-11763.
-
(2000)
J. Virol
, vol.74
, pp. 11754-11763
-
-
Zhou, T.1
Guo, J.T.2
Nunes, F.A.3
Molnar-Kimber, K.L.4
Wilson, J.M.5
Aldrich, C.E.6
Saputelli, J.7
Litwin, S.8
Condreay, L.D.9
Seeger, C.10
Mason, W.S.11
|