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Volumn 83, Issue 6, 2009, Pages 2663-2674

Treatment of chronic viral hepatitis in woodchucks by prolonged intrahepatic expression of interleukin-12

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; GAMMA INTERFERON; INTERLEUKIN 12; MEMBRANE ANTIGEN; MIFEPRISTONE; TRANSCRIPTION FACTOR FOXP3; VIRUS ANTIGEN; VIRUS DNA; FORKHEAD TRANSCRIPTION FACTOR;

EID: 62749092550     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02384-08     Document Type: Article
Times cited : (37)

References (33)
  • 2
    • 20844440410 scopus 로고    scopus 로고
    • IFN-alpha gene therapy for woodchuck hepatitis with adeno-associated virus: Differences in duration of gene expression and antiviral activity using intra-portal or intramuscular routes
    • Berraondo, P., L. Ochoa, J. Crettaz, F. Rotellar, A. Vales, E. Martinez-Anso, M. Zaratiegui, J. Ruiz, G. Gonzalez-Aseguinolaza, and J. Prieto. 2005. IFN-alpha gene therapy for woodchuck hepatitis with adeno-associated virus: differences in duration of gene expression and antiviral activity using intra-portal or intramuscular routes. Mol. Ther. 12:68-76.
    • (2005) Mol. Ther , vol.12 , pp. 68-76
    • Berraondo, P.1    Ochoa, L.2    Crettaz, J.3    Rotellar, F.4    Vales, A.5    Martinez-Anso, E.6    Zaratiegui, M.7    Ruiz, J.8    Gonzalez-Aseguinolaza, G.9    Prieto, J.10
  • 3
    • 33744808242 scopus 로고    scopus 로고
    • The immune response during hepatitis B virus infection
    • Bertoletti, A., and A. J. Gehring. 2006. The immune response during hepatitis B virus infection. J. Gen. Virol. 87:1439-1449.
    • (2006) J. Gen. Virol , vol.87 , pp. 1439-1449
    • Bertoletti, A.1    Gehring, A.J.2
  • 8
    • 0030997139 scopus 로고    scopus 로고
    • Interleukin-12 inhibits hepatitis B virus replication in transgenic mice
    • Cavanaugh, V. J., L. G. Guidotti, and F. V. Chisari. 1997. Interleukin-12 inhibits hepatitis B virus replication in transgenic mice. J. Virol. 71:3236-3243.
    • (1997) J. Virol , vol.71 , pp. 3236-3243
    • Cavanaugh, V.J.1    Guidotti, L.G.2    Chisari, F.V.3
  • 11
    • 0033617583 scopus 로고    scopus 로고
    • Viral clearance without destruction of infected cells during acute HBV infection
    • Guidotti, L. G., R. Rochford, J. Chung, M. Shapiro, R. Purcell, and F. V. Chisari. 1999. Viral clearance without destruction of infected cells during acute HBV infection. Science 284:825-829.
    • (1999) Science , vol.284 , pp. 825-829
    • Guidotti, L.G.1    Rochford, R.2    Chung, J.3    Shapiro, M.4    Purcell, R.5    Chisari, F.V.6
  • 12
    • 47049114816 scopus 로고    scopus 로고
    • Aberrant lymphocyte activation precedes delayed virus-specific T-cell response after both primary infection and secondary exposure to hepadnaviras in the woodchuck model of hepatitis B virus infection
    • Gujar, S. A., A. K. Jenkins, C. S. Guy, J. Wang, and T. I. Michalak. 2008. Aberrant lymphocyte activation precedes delayed virus-specific T-cell response after both primary infection and secondary exposure to hepadnaviras in the woodchuck model of hepatitis B virus infection. J. Virol. 82:6992-7008.
    • (2008) J. Virol , vol.82 , pp. 6992-7008
    • Gujar, S.A.1    Jenkins, A.K.2    Guy, C.S.3    Wang, J.4    Michalak, T.I.5
  • 14
    • 0036268305 scopus 로고    scopus 로고
    • Long-term transgene expression in the RPE after gene transfer with a high-capacity adenoviral vector
    • Kreppel, F., T. T. Luther, I. Semkova, U. Schraermeyer, and S. Kochanek. 2002. Long-term transgene expression in the RPE after gene transfer with a high-capacity adenoviral vector. Investig. Ophthalmol. Vis. Sci. 43:1965-1970.
    • (2002) Investig. Ophthalmol. Vis. Sci , vol.43 , pp. 1965-1970
    • Kreppel, F.1    Luther, T.T.2    Semkova, I.3    Schraermeyer, U.4    Kochanek, S.5
  • 15
    • 0036378341 scopus 로고    scopus 로고
    • Reduced virus specific T helper cell induction by autologous dendritic cells in patients with chronic hepatitis B-restoration by exogenous interleukin-12
    • Lohr, H. F., S. Pingel, W. O. Bocher, H. Bernhard, S. Herzog-Hauff, S. Rose-John, and P. R. Galle. 2002. Reduced virus specific T helper cell induction by autologous dendritic cells in patients with chronic hepatitis B-restoration by exogenous interleukin-12. Clin. Exp. Immunol. 130:107-114.
    • (2002) Clin. Exp. Immunol , vol.130 , pp. 107-114
    • Lohr, H.F.1    Pingel, S.2    Bocher, W.O.3    Bernhard, H.4    Herzog-Hauff, S.5    Rose-John, S.6    Galle, P.R.7
  • 16
    • 34247268523 scopus 로고    scopus 로고
    • Navigating the maze of hepatitis B treatments
    • Lok, A. S. 2007. Navigating the maze of hepatitis B treatments. Gastroen-terology 132:1586-1594.
    • (2007) Gastroen-terology , vol.132 , pp. 1586-1594
    • Lok, A.S.1
  • 17
    • 33847406557 scopus 로고    scopus 로고
    • PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver
    • Maier, H., M. Isogawa, G. J. Freeman, and F. V. Chisari. 2007. PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver. J. Immunol. 178:2714- 2720.
    • (2007) J. Immunol , vol.178 , pp. 2714-2720
    • Maier, H.1    Isogawa, M.2    Freeman, G.J.3    Chisari, F.V.4
  • 18
    • 33846534236 scopus 로고    scopus 로고
    • The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infection
    • Menne, S., and P. J. Cote. 2007. The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infection. World J. Gastroenterology 13:104-124.
    • (2007) World J. Gastroenterology , vol.13 , pp. 104-124
    • Menne, S.1    Cote, P.J.2
  • 19
    • 64249142159 scopus 로고    scopus 로고
    • Chemo-immu-notherapy of chronic hepatitis B virus infection in the woodchuck model breaks immunologic tolerance and restores T-cell responses to PreS and S regions of the viral envelope protein
    • Menne, S., B. C. Tennant, J. L. Gerin, and P. J. Cote. 2007. Chemo-immu-notherapy of chronic hepatitis B virus infection in the woodchuck model breaks immunologic tolerance and restores T-cell responses to PreS and S regions of the viral envelope protein. J. Virol. 51:3177-3184.
    • (2007) J. Virol , vol.51 , pp. 3177-3184
    • Menne, S.1    Tennant, B.C.2    Gerin, J.L.3    Cote, P.J.4
  • 20
    • 0033054559 scopus 로고    scopus 로고
    • Down-regulation of the pharmacokinetic-pharmacody-namic response to interleukin-12 during long-term administration to patients with renal cell carcinoma and evaluation of the mechanism of this "adaptive response" in mice
    • Rakhit, A., M. M. Yeon, J. Ferrante, S. Fettner, R. Nadeau, R. Motzer, R. Bukowski, D. M. Carvajal, V. L. Wilkinson, D. H. Presky, J. Magram, and M. K. Gately. 1999. Down-regulation of the pharmacokinetic-pharmacody-namic response to interleukin-12 during long-term administration to patients with renal cell carcinoma and evaluation of the mechanism of this "adaptive response" in mice. Clin. Pharmacol. Ther. 65:615-629.
    • (1999) Clin. Pharmacol. Ther , vol.65 , pp. 615-629
    • Rakhit, A.1    Yeon, M.M.2    Ferrante, J.3    Fettner, S.4    Nadeau, R.5    Motzer, R.6    Bukowski, R.7    Carvajal, D.M.8    Wilkinson, V.L.9    Presky, D.H.10    Magram, J.11    Gately, M.K.12
  • 21
    • 30944449094 scopus 로고    scopus 로고
    • Lamivudine plus interleukin-12 combination therapy in chronic hepatitis B: Antiviral and immunological activity
    • Rigopoulou, E. I., D. Suri, S. Chokshi, I. Mullerova, S. Rice, R. S. Tedder, R. Williams, and N. V. Naoumov. 2005. Lamivudine plus interleukin-12 combination therapy in chronic hepatitis B: antiviral and immunological activity. Hepatology 42:1028-1036.
    • (2005) Hepatology , vol.42 , pp. 1028-1036
    • Rigopoulou, E.I.1    Suri, D.2    Chokshi, S.3    Mullerova, I.4    Rice, S.5    Tedder, R.S.6    Williams, R.7    Naoumov, N.V.8
  • 22
    • 0030959049 scopus 로고    scopus 로고
    • Interleukin-12 induction of Thl cytokines is important for viral clearance in chronic hepatitis B
    • Rossol, S., G. Marinos, P. Carucci, M. V. Singer, R. Williams, and N. V. Naoumov. 1997. Interleukin-12 induction of Thl cytokines is important for viral clearance in chronic hepatitis B. J. Clin. Investig. 99:3025-3033.
    • (1997) J. Clin. Investig , vol.99 , pp. 3025-3033
    • Rossol, S.1    Marinos, G.2    Carucci, P.3    Singer, M.V.4    Williams, R.5    Naoumov, N.V.6
  • 23
    • 36048996837 scopus 로고    scopus 로고
    • T-regulatory lymphocytes and chronic viral hepatitis
    • Rushbrook, S. M., M. Hoare, and G. J. Alexander. 2007. T-regulatory lymphocytes and chronic viral hepatitis. Exp. Opin. Biol. Ther. 7:1689-1703.
    • (2007) Exp. Opin. Biol. Ther , vol.7 , pp. 1689-1703
    • Rushbrook, S.M.1    Hoare, M.2    Alexander, G.J.3
  • 24
    • 0032992117 scopus 로고    scopus 로고
    • The presence of high amounts of HBV-DNA in serum is associated with suppressed costimulatory effects of interleukin 12 on HBV-induced immune response
    • Schlaak, J. F., G. Tully, H. F. Lohr, G. Gerken, and K. H. Meyer zum Biischenfelde. 1999. The presence of high amounts of HBV-DNA in serum is associated with suppressed costimulatory effects of interleukin 12 on HBV-induced immune response. J. Hepatol. 30:353-358.
    • (1999) J. Hepatol , vol.30 , pp. 353-358
    • Schlaak, J.F.1    Tully, G.2    Lohr, H.F.3    Gerken, G.4    Meyer zum Biischenfelde, K.H.5
  • 25
    • 1842735646 scopus 로고    scopus 로고
    • Quantitation of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) in the liver of HBV-infected patients by LightCycler real-time PCR
    • Singh, M, A. Dicaire, A. E. Wakil, C. Luscombe, and S. L. Sacks. 2004. Quantitation of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) in the liver of HBV-infected patients by LightCycler real-time PCR. J. Virol. Methods 118:159-167.
    • (2004) J. Virol. Methods , vol.118 , pp. 159-167
    • Singh, M.1    Dicaire, A.2    Wakil, A.E.3    Luscombe, C.4    Sacks, S.L.5
  • 26
  • 27
    • 34047266620 scopus 로고    scopus 로고
    • Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B
    • Stoop, J. N., R. G. van der Molen, E. J. Kuipers, J. G. Kusters, and H. L. Janssen. 2007. Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B. Virology 361:141-148.
    • (2007) Virology , vol.361 , pp. 141-148
    • Stoop, J.N.1    van der Molen, R.G.2    Kuipers, E.J.3    Kusters, J.G.4    Janssen, H.L.5
  • 29
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri, G. 2003. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3:133-146.
    • (2003) Nat. Rev. Immunol , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 31
    • 33947397924 scopus 로고    scopus 로고
    • IL-12 promotes HBV-specific central memory CD8+ T cell responses by PBMCs from chronic hepatitis B virus carriers
    • Xiong, S. Q., B. L. Lin, X. Gao, H. Tang, and C. Y. Wu. 2007. IL-12 promotes HBV-specific central memory CD8+ T cell responses by PBMCs from chronic hepatitis B virus carriers. Int. Immunopharmacol. 7:578-587.
    • (2007) Int. Immunopharmacol , vol.7 , pp. 578-587
    • Xiong, S.Q.1    Lin, B.L.2    Gao, X.3    Tang, H.4    Wu, C.Y.5
  • 32
    • 33947699267 scopus 로고    scopus 로고
    • Molecular mechanisms of resistance to antiviral therapy in patients with chronic hepatitis B
    • Yuan, H. J., and W. M. Lee. 2007. Molecular mechanisms of resistance to antiviral therapy in patients with chronic hepatitis B. Curr. Mol. Med. 7:185-197.
    • (2007) Curr. Mol. Med , vol.7 , pp. 185-197
    • Yuan, H.J.1    Lee, W.M.2


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