Long runs of homozygosity are enriched for deleterious variation

American Journal of Human Genetics

Volumn 93, Issue 1, 2013, Pages 90-102

  Szpiech, Zachary A ^a,b   Xu, Jishu ^c   Pemberton, Trevor J ^b,d   Peng, Weiping ^c   Zöllner, Sebastian ^e,f   Rosenberg, Noah A ^b   Li, Jun Z ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF MANITOBA   (Canada)

^e UNIVERSITY OF MICHIGAN   (United States)

^f UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONSANGUINITY; CONTROLLED STUDY; EXOME; GENE DELETION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOME; GENOMICS; GENOTYPE; HOMOZYGOSITY; HOMOZYGOTE; HUMAN; HYPOTHESIS; INBREEDING; NATURAL SELECTION; POPULATION SIZE; PREDICTION; PRIORITY JOURNAL; RUNS OF HOMOZYGOSITY;

ALLELES; COMPUTATIONAL BIOLOGY; CONSANGUINITY; EXOME; GENETICS, POPULATION; GENOME, HUMAN; GENOMIC STRUCTURAL VARIATION; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MUTATION, MISSENSE; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDICTIVE VALUE OF TESTS;

EID: 84880260767     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2013.05.003     Document Type: Article

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