A systematic approach to mapping recessive disease genes in individuals from outbred populations

PLoS Genetics

Volumn 5, Issue 1, 2009, Pages

  Hildebrandt, Friedhelm ^a   Heeringa, Saskia F ^a   Rüschendorf, Franz ^b   Attanasio, Massimo ^a   Nürnberg, Gudrun ^c,d   Becker, Christian ^c,d   Seelow, Dominik ^c,d,e   Huebner, Norbert ^e   Chernin, Gil ^a   Vlangos, Christopher N ^a   Zhou, Weibin ^a   O'Toole, John F ^a   Hoskins, Bethan E ^a   Wolf, Matthias T F ^a   Hinkes, Bernward G ^a   Chaib, Hassan ^a   Ashraf, Shazia ^a   Allen, Susan J ^a   Vega Warner, Virginia ^a   Wise, Eric ^a   Harville, Heather M ^a   Lyons, Robert H ^a   Washburn, Joseph ^f   MacDonald, James ^a,f   Nürnberg, Peter ^c,d   Otto, Edgar A ^a   more..

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d UNIVERSITY OF COLOGNE   (Germany)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^f UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONSANGUINITY; CONTROLLED STUDY; FALSE POSITIVE RESULT; GENE MAPPING; GENE MUTATION; GENETIC DISORDER; GENOME; HOMOZYGOSITY; HUMAN; INBREEDING; RECESSIVE GENE; RECESSIVE INHERITANCE; SINGLE NUCLEOTIDE POLYMORPHISM; BIOLOGICAL MODEL; FAMILY HEALTH; FEMALE; GENETIC MARKER; GENETICS; HOMOZYGOTE; KIDNEY POLYCYSTIC DISEASE; LABORATORY DIAGNOSIS; MALE; NEPHROTIC SYNDROME; NUCLEOTIDE SEQUENCE; PEDIGREE; POPULATION GENETICS;

STEROID;

DNA MUTATIONAL ANALYSIS; FALSE POSITIVE REACTIONS; FAMILY HEALTH; FEMALE; GENES, RECESSIVE; GENETIC MARKERS; GENETICS, POPULATION; HOMOZYGOTE; HUMANS; KIDNEY DISEASES, CYSTIC; MALE; MODELS, GENETIC; NEPHROTIC SYNDROME; PEDIGREE; STEROIDS;

EID: 59249092391     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000353     Document Type: Article

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