A resolution of the mutation load paradox in humans

Genetics

Volumn 191, Issue 4, 2012, Pages 1321-1330

  Lesecque, Yann ^a,b,d   Keightley, Peter D ^c   Eyre Walker, Adam ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UNIVERSITÉ DE LYON   (France)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d LABORATOIRE DE BIOMÉTRIE ET BIOLOGIE EVOLUTIVE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DELETION MUTANT; FITNESS; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENETIC MODEL; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN GENOME; POPULATION SIZE; PREDICTIVE VALUE; PRIORITY JOURNAL; RECESSIVE INHERITANCE; SIMULATION;

ALGORITHMS; COMPUTER SIMULATION; EVOLUTION, MOLECULAR; FEMALE; GENES, RECESSIVE; GENETIC FITNESS; GENETICS, POPULATION; HUMANS; MALE; MODELS, GENETIC; MUTATION; MUTATION RATE; REPRODUCTION; SELECTION, GENETIC;

EID: 84865096270     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.112.140343     Document Type: Article

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