Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Fu, Lingyi ^a   Chen, Wangbing ^a   Guo, Wei ^b   Wang, Jingshu ^a   Tian, Yun ^a   Shi, Dingbo ^a   Zhang, Xiaohong ^b   Qiu, Huijuan ^a   Xiao, Xiangsheng ^a   Kang, Tiebang ^a   Huang, Wenlin ^a,c   Wang, Shusen ^a   Deng, Wuguo ^a,b,c  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b DALIAN MEDICAL UNIVERSITY   (China)

^c Guangzhou Double Bioproduct Inc   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BERBERINE; CASPASE; CYCLOOXYGENASE 2; CYTOCHROME C; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; TELOMERASE REVERSE TRANSCRIPTASE; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR AP 2ALPHA; TRANSCRIPTION FACTOR AP 2BETA; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; VASCULOTROPIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; COLONY FORMATION; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; DRUG MECHANISM; DRUG TARGETING; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LUNG NON SMALL CELL CANCER; MITOCHONDRIAL MEMBRANE; PROMOTER REGION; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BERBERINE; CARCINOMA, NON-SMALL-CELL LUNG; CASPASES; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CYCLOOXYGENASE 2; CYTOCHROMES C; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LUNG NEOPLASMS; NF-KAPPA B; SIGNAL TRANSDUCTION; TELOMERASE; TRANSCRIPTION FACTOR AP-2; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84880252424     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069240     Document Type: Article

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