Protective effects of berberine on radiation-induced lung injury via intercellular adhesion molecular-1 and transforming growth factor-beta-1 in patients with lung cancer

European Journal of Cancer

Volumn 44, Issue 16, 2008, Pages 2425-2432

  Liu, Yunfang ^a   Yu, Huiming ^b   Zhang, Cheng ^a   Cheng, Yufeng ^b   Hu, Likuan ^b   Meng, Xiaohui ^a   Zhao, Yuxia ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Berberine; Intercellular adhesion molecular 1; Non small cell lung cancer; Radiation induced lung injury; Transforming growth factor beta 1

Indexed keywords

BERBERINE; INTERCELLULAR ADHESION MOLECULE 1; PLACEBO; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ARTICLE; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOUBLE BLIND PROCEDURE; ESOPHAGITIS; FORCED EXPIRATORY VOLUME; HUMAN; LEUKOPENIA; LUNG FUNCTION; LUNG INJURY; LUNG NON SMALL CELL CANCER; NAUSEA; NAUSEA AND VOMITING; PRIORITY JOURNAL; RADIATION INDUCED EMESIS; RADIATION INJURY; RANDOMIZED CONTROLLED TRIAL; STUDENT T TEST;

AGED; BERBERINE; CARCINOMA, NON-SMALL-CELL LUNG; COMBINED MODALITY THERAPY; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LUNG; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RADIATION INJURIES; RADIATION-PROTECTIVE AGENTS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 54249159100     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2008.07.040     Document Type: Article

References (38)

1. Fan M., Marks L.B., Hollis D., et al. Can we predict radiation-induced changes in pulmonary function based on the sum of predicted regional dysfunction?. J Clin Oncol 19 (2001) 543-550
2. Kong F.M., Ten Haken R., Eisbruch A., and Lawrence T.S. Non-small cell lung cancer therapy-related pulmonary toxicity: an update on radiation pneumonitis and fibrosis. Semin Oncol 32 (2005) S42-S54
3. Hallahan D.E., and Virudachalam S. Ionizing radiation mediates expression of cell adhesion molecules in distinct histological patterns within the lung. Cancer Res 57 (1997) 2096-2099
4. Burger A., Löffler H., Bamberg M., and Rodemann H.P. Molecular and cellular basis of radiation fibrosis. Int J Radiat Biol 73 (1998) 401-408
5. Tsoutsou P.G., and Koukourakis M.I. Radiation pneumonitis and fibrosis: mechanisms underlying its pathogenesis and implications for future research. Int J Radiat Oncol Biol Phys 66 (2006) 1281-1293
6. Fleckenstein K., Gauter-Fleckenstein B., Jackson I.L., Rabbani Z., Anscher M., and Vujaskovic Z. Using biological markers to predict risk of radiation injury. Semin Radiat Oncol 17 (2007) 89-98
7. Luscinskas F.W., Cybulsky M.I., Kiely J.M., Peckins C.S., Davis V.M., and Gimbrone Jr. M.A. Cytokine-activated human endothelial monolayers support enhanced neutrophil transmigration via a mechanism involving both endothelial-leukocyte adhesion molecule-1 and intercellular adhesion molecule-1. J Immunol 146 (1991) 1617-1625
8. Hallahan D., Kuchibhotla J., and Wyble C. Cell adhesion molecules mediate radiation-induced leukocyte adhesion to the vascular endothelium. Cancer Res 56 (1996) 5150-5155
9. Kawana A., Shioya S., Katoh H., Tsuji C., Tsuda M., and Ohta Y. Expression of intercellular adhesion molecule-1 and lymphocyte function-associated antigen-1 on alveolar macrophages in the acute stage of radiation-induced lung injury in rats. Radiat Res 147 (1997) 431-436
10. Hallahan D.E., and Virudachalam S. Intercellular adhesion molecule 1 knockout abrogates radiation induced pulmonary inflammation. Proc Natl Acad Sci USA 94 (1997) 6432-6437
11. Vujaskovic Z., Feng Q.F., Rabbani Z.N., Samulski T.V., Anscher M.S., and Brizel D.M. Assessment of the protective effect of amifostine on radiation-induced pulmonary toxicity. Exp Lung Res 28 (2002) 577-590
12. Ishii Y., and Kitamura S. Soluble intercellular adhesion molecule-1 as an early detection marker for radiation pneumonitis. Eur Respir J 13 (1999) 733-738
13. Kosaka Y., Mitsumori M., Araki N., et al. Avascular necrosis of bilateral femoral head as a result of long-term steroid administration for radiation pneumonitis after tangential irradiation of the breast. Int J Clin Oncol 11 (2006) 482-486
14. Yesilada E., and Kupeli E. Berberis crataegina DC root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats. J Ethnopharmacol 79 (2002) 237-248
15. Lee D.U., Kang Y.J., Park M.K., et al. Effects of 13-alkyl-substituted berberine alkaloids on the expression of COX-II, TNF-a, iNOS, and IL-12 production in LPS-stimulated macrophages. Life Sci 73 (2003) 1401-1412
16. Lee C.H., Chen J.C., Hsiang C.Y., Wu S.L., Wu H.C., and Ho T.Y. Berberine suppresses inflammatory agents-induced interleukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells. Pharmacol Res 56 (2007) 193-201
17. Zhang B.J., Xu D., Guo Y., Ping J., Chen L.B., and Wang H. Protection by and anti-oxidant mechanism of berberine against rat liver fibrosis induced by multiple hepatotoxic factors. Clin Exp Pharmacol Physiol 35 (2008) 303-309
18. Yeşilada E., and Küpeli E. Berberis crataegina DC root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats. J Ethnopharmacol 79 (2002) 237-248
19. Shirwaikar A., Shirwaikar A., Rajendran K., and Punitha I.S. In vitro antioxidant studies on the benzyl tetra isoquinoline alkaloid berberine. Biol Pharm Bull 29 (2006) 1906-1910
20. ICRU-50: Prescribing, Recording, Reporting, Photon Beam Therapy. Washington, DC: International Commission on Radiation Units and Measurements; 1994.
21. LENT SOMA tables. Radiother Oncol 1995;35:17-60.
22. Anscher M.S. The irreversibility of radiation-induced fibrosis: fact or folklore?. J Clin Oncol 23 (2005) 8551-8552
23. Lujun Z., Kerby S., Ming C., et al. The predictive role of plasma TGF-β1 during radiation therapy for radiation-induced lung toxicity deserves further study in patients with non-small cell lung cancer. Lung Cancer 59 (2008) 232-239
24. Evans E.S., Kocak Z., Zhou S.M., et al. Does transforming growth factor-beta1 predict for radiation-induced pneumonitis in patients treated for lung cancer?. Cytokine 35 (2006) 186-192
25. Xavier S., Piek E., Fujii M., et al. Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone. J Biol Chem 279 (2004) 15167-15176
26. Anscher M.S., Marks L.B., Shafman T.D., et al. Risk of long-term complications after TFG-beta1-guided very-high-dose thoracic radiotherapy. Int J Radiat Oncol Biol Phys 56 (2003) 988-995
27. Novakova-Jiresova A., Van Gameren M.M., Coppes R.P., Kampinga H.H., and Groen H.J. Transforming growth factor-beta plasma dynamics and post-irradiation lung injury in lung cancer patients. Radiother Oncol 71 (2004) 183-189
28. Haiping Z., Takayama K., Uchino J., et al. Prevention of radiation-induced pneumonitis by recombinant adenovirus-mediated transferring of soluble TGF-beta type II receptor gene. Cancer Gene Ther 13 (2006) 864-872
29. Anscher M.S., Thrasher B., Rabbani Z., Teicher B., and Vujaskovic Z. Antitransforming growth factor-β antibody 1D11 ameliorates normal tissue damage caused by high-dose radiation. Int J Radiat Oncol Biol Phys 65 (2006) 876-881
30. Fakler C.R., Wu B., McMicken H.W., Geske R.S., and Welty S.E. Molecular mechanisms of lipopolysaccharide induced ICAM-1 expression in A549 cells. Inflam Res 49 (2000) 63-72
31. Marlin S.D., and Springer T.A. Purified intercellular adhesion molecule 1 (ICAM-1) is a ligand for lymphocyte function associated antigen-1 (LFA-1). Cell 51 (1987) 813-819
32. Butcher E.C. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67 (1991) 1033-1036
33. Komaki R., Lee J.S., Milas L., et al. Effects of amifostine on acute toxicity from concurrent chemotherapy and radiotherapy for inoperable non-small-cell lung cancer: report of a randomized comparative trial. Int J Radiat Oncol Biol Phys 58 (2004) 1369-1377
34. Murshed H., Liu H.H., Liao Z., et al. Dose and volume reduction for normal lung using intensity-modulated radiotherapy for advanced-stage non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 58 (2004) 1258-1267
35. Kuo C.L., Chi C.W., and Liu T.Y. The anti-inflammatory potential of berberine in vitro and in vivo. Cancer Lett 203 (2004) 127-137
36. Peng P.L., Hsieh Y.S., Wang C.J., Hsu J.L., and Chou F.P. Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2. Toxicol Appl Pharmacol 214 (2006) 8-15
37. Peng P.L., Kuo W.H., Tseng H.C., and Chou F.P. Synergistic tumor-killing effect of radiation and berberine combined treatment in lung cancer: the contribution of autophagic cell death. Int J Radiat Oncol Biol Phys 70 (2008) 529-542
38. Hu J.P., Nishishita K., Sakai E., et al. Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-kappaB and Akt pathways. Eur J Pharmacol 580 (2008) 70-79