-
1
-
-
72949093335
-
From pathogenesis to treatment of chronic lymphocytic leukaemia
-
An excellent review of the genetic and molecular mechanisms involved in the pathogenesis of the disease and their clinical implications
-
Zenz T, Mertens D, Kuppers R, et al. From pathogenesis to treatment of chronic lymphocytic leukaemia. Nat Rev Cancer 2010; 10:37-50. An excellent review of the genetic and molecular mechanisms involved in the pathogenesis of the disease and their clinical implications.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 37-50
-
-
Zenz, T.1
Mertens, D.2
Kuppers, R.3
-
2
-
-
84867154468
-
Molecular pathogenesis of chronic lymphocytic leukemia
-
An excellent review of the genetic and molecular mechanisms involved in the pathogenesis of the disease and their clinical implications
-
Gaidano G, Foa R, Dalla-Favera R. Molecular pathogenesis of chronic lymphocytic leukemia. J Clin Invest 2012; 122:3432-3438. An excellent review of the genetic and molecular mechanisms involved in the pathogenesis of the disease and their clinical implications.
-
(2012)
J Clin Invest
, vol.122
, pp. 3432-3438
-
-
Gaidano, G.1
Foa, R.2
Dalla-Favera, R.3
-
3
-
-
0034727833
-
Genomic aberrations and survival in chronic lymphocytic leukemia
-
Dohner H, Stilgenbauer S, Benner A, et al. Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med 2000; 343:1910-1916.
-
(2000)
N Engl J Med
, vol.343
, pp. 1910-1916
-
-
Dohner, H.1
Stilgenbauer, S.2
Benner, A.3
-
4
-
-
80053144962
-
A decade of exploring the cancer epigenome: Biological and translational implications
-
Baylin SB, Jones PA. A decade of exploring the cancer epigenome: biological and translational implications. Nat Rev Cancer 2011; 11:726-734.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 726-726
-
-
Baylin, S.B.1
Jones, P.A.2
-
5
-
-
75649133610
-
Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia
-
Kanduri M, Cahill N, Goransson H, et al. Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia. Blood 2010; 115:296-305.
-
(2010)
Blood
, vol.115
, pp. 296-305
-
-
Kanduri, M.1
Cahill, N.2
Goransson, H.3
-
6
-
-
77956838065
-
Advances in understanding cancer genomes through second-generation sequencing
-
Meyerson M, Gabriel S, Getz G. Advances in understanding cancer genomes through second-generation sequencing. Nat Rev Genet 2010; 11:685-696.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 685-696
-
-
Meyerson, M.1
Gabriel, S.2
Getz, G.3
-
7
-
-
79960036578
-
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
-
This is the first whole-genome
-
Puente XS, Pinyol M, Quesada V, et al. Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature 2011; 475: 101-105. This is the first whole-genome sequence analysis of CLL, which identifies several recurrent mutations and reveals their functional and clinical impact highlighting the relevance of next-generation sequencing studies in understanding this disease
-
(2011)
Nature
, vol.475
, pp. 101-105
-
-
Puente, X.S.1
Pinyol, M.2
Quesada, V.3
-
8
-
-
79960353160
-
Analysis of the chronic lymphocytic leukemia coding genome: Role of NOTCH1 mutational activation
-
Fabbri G, Rasi S, Rossi D, et al. Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation. J Exp Med 2011; 208:1389-1401. This study offers the first comprehensive catalog of recurrent somatic mutations in CLL and discovers new mechanisms in the pathogenesis of the disease.
-
(2011)
J Exp Med
, vol.208
, pp. 1389-1401
-
-
Fabbri, G.1
Rasi, S.2
Rossi, D.3
-
9
-
-
84555171449
-
Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukaemia
-
Quesada V, Conde L, Villamor N, et al. Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia. Nat Genet 2011; 44:47-52.This study offers the first comprehensive catalog of recurrent somatic mutations in CLL and discovers new mechanisms in the pathogenesis of the disease
-
(2011)
Nat Genet
, vol.44
, pp. 47-52
-
-
Quesada, V.1
Conde, L.2
Villamor, N.3
-
10
-
-
84855370035
-
SF3B1 and other novel cancer genes in chronic lymphocytic leukaemia
-
Wang L, Lawrence MS, Wan Y, et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med 2011; 365:2497-2506.
-
(2011)
N Engl J Med
, vol.365
, pp. 2497-2506
-
-
Wang, L.1
Lawrence, M.S.2
Wan, Y.3
-
11
-
-
84855597743
-
Simple genetic diagnosis of hairy cell leukemia by sensitive detection of the BRAF-V600E mutation
-
Tiacci E, Schiavoni G, Forconi F, et al. Simple genetic diagnosis of hairy cell leukemia by sensitive detection of the BRAF-V600E mutation. Blood 2012; 119:192-195.
-
(2012)
Blood
, vol.119
, pp. 192-195
-
-
Tiacci, E.1
Schiavoni, G.2
Forconi, F.3
-
12
-
-
80052029516
-
Frequent mutation of histonemodifying genes in non-Hodgkin lymphoma
-
Morin RD, Mendez-Lago M, Mungall AJ, et al. Frequent mutation of histonemodifying genes in non-Hodgkin lymphoma. Nature 2011; 476:298-303.
-
(2011)
Nature
, vol.476
, pp. 298-303
-
-
Morin, R.D.1
Mendez-Lago, M.2
Mungall, A.J.3
-
13
-
-
84857942952
-
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
-
Lohr JG, Stojanov P, Lawrence MS, et al. Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. Proc Natl Acad Sci USA 2012; 109:3879-3884.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 3879-3884
-
-
Lohr, J.G.1
Stojanov, P.2
Lawrence, M.S.3
-
14
-
-
84872856782
-
Genetic heterogeneity of diffuse large B-cell lymphoma
-
Zhang J, Grubor V, Love CL, et al. Genetic heterogeneity of diffuse large B-cell lymphoma. Proc Natl Acad Sci USA 2013; 110:1398-1403.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 1398-1403
-
-
Zhang, J.1
Grubor, V.2
Love, C.L.3
-
15
-
-
80052269038
-
Analysis of the coding genome of diffuse large B-cell lymphoma
-
Pasqualucci L, Trifonov V, Fabbri G, et al. Analysis of the coding genome of diffuse large B-cell lymphoma. Nat Genet 2011; 43:830-837.
-
(2011)
Nat Genet
, vol.43
, pp. 830-837
-
-
Pasqualucci, L.1
Trifonov, V.2
Fabbri, G.3
-
16
-
-
84867051939
-
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
-
Schmitz R, Young RM, Ceribelli M, et al. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature 2012; 490:116-120.
-
(2012)
Nature
, vol.490
, pp. 116-120
-
-
Schmitz, R.1
Young, R.M.2
Ceribelli, M.3
-
17
-
-
84870544677
-
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing
-
Richter J, Schlesner M, Hoffmann S, et al. Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing. Nat Genet 2012; 44:1316-1320.
-
(2012)
Nat Genet
, vol.44
, pp. 1316-1320
-
-
Richter, J.1
Schlesner, M.2
Hoffmann, S.3
-
18
-
-
84870538715
-
The genetic landscape of mutations in Burkitt lymphoma
-
Love C, Sun Z, Jima D, et al. The genetic landscape of mutations in Burkitt lymphoma. Nat Genet 2012; 44:1321-1325.
-
(2012)
Nat Genet
, vol.44
, pp. 1321-1325
-
-
Love, C.1
Sun, Z.2
Jima, D.3
-
19
-
-
79951494668
-
Initial genome sequencing and analysis of multiple myeloma
-
Chapman MA, Lawrence MS, Keats JJ, et al. Initial genome sequencing and analysis of multiple myeloma. Nature 2011; 471:467-472.
-
(2011)
Nature
, vol.471
, pp. 467-472
-
-
Chapman, M.A.1
Lawrence, M.S.2
Keats, J.J.3
-
20
-
-
79951498701
-
Cellular origin(s) of chronic lymphocytic leukemia: Cautionary notes and additional considerations and possibilities
-
Chiorazzi N, Ferrarini M. Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities. Blood 2011; 117:1781-1791.
-
(2011)
Blood
, vol.117
, pp. 1781-1791
-
-
Chiorazzi, N.1
Ferrarini, M.2
-
21
-
-
0035803464
-
Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells
-
Klein U, Tu Y, Stolovitzky GA, et al. Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells. J Exp Med 2001; 194:1625-1638.
-
(2001)
J Exp Med
, vol.194
, pp. 1625-1638
-
-
Klein, U.1
Tu, Y.2
Stolovitzky, G.A.3
-
22
-
-
84868198427
-
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukaemia
-
This is the first genome-wide methylome study in CLL including the whole-genome bisulfite sequencing of several subpopulations of normal B-lymphocytes and tumor samples. The study reveals the complex epigenetic reprogramming of the methylome profile in the development of CLL
-
Kulis M, Heath S, Bibikova M, et al. Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia. Nat Genet 2012; 44:1236-1242. This is the first genome-wide methylome study in CLL including the whole-genome bisulfite sequencing of several subpopulations of normal B-lymphocytes and tumor samples. The study reveals the complex epigenetic reprogramming of the methylome profile in the development of CLL
-
(2012)
Nat Genet
, vol.44
, pp. 1236-1242
-
-
Kulis Heath M, S.1
Bibikova, M.2
-
23
-
-
84872342533
-
Cellular origin and pathophysiology of chronic lymphocytic leukaemia
-
Seifert M, Sellmann L, Bloehdorn J, et al. Cellular origin and pathophysiology of chronic lymphocytic leukemia. J Exp Med 2012; 209:2183- 2198. This elegant study identifies mature CD5(Ã) B and a previously unrecognized CD5(Ã)CD27(Ã) postgerminal center B cell as the cells of origin of CLL with unmutated and mutated IGHV, respectively
-
(2012)
J Exp Med
, vol.209
, pp. 2183-2183
-
-
Seifert, M.1
Sellmann, L.2
Bloehdorn, J.3
-
24
-
-
80051589767
-
Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukaemia
-
Kikushige Y, Ishikawa F, Miyamoto T, et al. Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia. Cancer Cell 2011; 20:246-259 This study presents intriguing observations, suggesting that hematopoietic stem cells may be already primed to develop clonal proliferation of mature B-cells with CLL features.
-
(2011)
Cancer Cell
, vol.20
, pp. 246-259
-
-
Kikushige, Y.1
Ishikawa, F.2
Miyamoto, T.3
-
25
-
-
84877106592
-
The genomic landscape of chronic lymphocytic leukemia
-
Quesada V, Ramsay AJ, Rodriguez D, et al. The genomic landscape of chronic lymphocytic leukemia. BMC Med 2013; 11:124.
-
(2013)
BMC Med
, vol.11
, pp. 124
-
-
Quesada, V.1
Ramsay, A.J.2
Rodriguez, D.3
-
26
-
-
84880322359
-
Frequent somatic mutations in components of the RNA processing machinery in chronic lymphocytic leukemia
-
Epub ahead of print
-
Ramsay AJ, Rodriguez D, Villamor N, et al. Frequent somatic mutations in components of the RNA processing machinery in chronic lymphocytic leukemia. Leukemia 2012. [Epub ahead of print].
-
(2012)
Leukemia
-
-
Ramsay, A.J.1
Rodriguez, D.2
Villamor, N.3
-
27
-
-
84861541343
-
Mutational processes molding the genomes of 21 breast cancers
-
Nik-Zainal S, Alexandrov LB, Wedge DC, et al. Mutational processes molding the genomes of 21 breast cancers. Cell 2012; 149:979-993.
-
(2012)
Cell
, vol.149
, pp. 979-993
-
-
Nik-Zainal, S.1
Alexandrov, L.B.2
Wedge, D.C.3
-
28
-
-
84861550476
-
The life history of 21 breast cancers
-
Nik-Zainal S, Van LP, Wedge DC, et al. The life history of 21 breast cancers. Cell 2012; 149:994-1007.
-
(2012)
Cell
, vol.149
, pp. 994-1007
-
-
Nik-Zainal, S.1
Van Lp Wedge, D.C.2
-
29
-
-
74449085934
-
A small-cell lung cancer genome with complex signatures of tobacco exposure
-
Pleasance ED, Stephens PJ, O'Meara S, et al. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature 2010; 463: 184-190.
-
(2010)
Nature
, vol.463
, pp. 184-190
-
-
Pleasance, E.D.1
Stephens, P.J.2
O'meara, S.3
-
30
-
-
84861922114
-
Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia
-
Pei L, Choi JH, Liu J, et al. Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia. Epigenetics 2012; 7:567-578.
-
(2012)
Epigenetics
, vol.7
, pp. 567-578
-
-
Pei, L.1
Choi, J.H.2
Liu, J.3
-
31
-
-
84873570131
-
450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments
-
Cahill N, Bergh AC, Kanduri M, et al. 450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments. Leukemia 2013; 27:150-158.
-
(2013)
Leukemia
, vol.27
, pp. 150-158
-
-
Cahill, N.1
Bergh, A.C.2
Kanduri, M.3
-
32
-
-
77954126563
-
Large-scale analysis of DNA methylation in chronic lymphocytic leukemia
-
Rahmatpanah FB, Carstens S, Hooshmand SI, et al. Large-scale analysis of DNA methylation in chronic lymphocytic leukemia. Epigenomics 2009; 1: 39-61.
-
(2009)
Epigenomics
, vol.1
, pp. 39-61
-
-
Rahmatpanah, F.B.1
Carstens, S.2
Hooshmand, S.I.3
-
33
-
-
84864856010
-
Extensive promoter DNA hypermethylation and hypomethylation is associated with aberrant microRNA expression in chronic lymphocytic leukemia
-
Baer C, Claus R, Frenzel LP, et al. Extensive promoter DNA hypermethylation and hypomethylation is associated with aberrant microRNA expression in chronic lymphocytic leukemia. Cancer Res 2012; 72:3775-3785.
-
(2012)
Cancer Res
, vol.72
, pp. 3775-3785
-
-
Baer, C.1
Claus, R.2
Frenzel, L.P.3
-
34
-
-
84870735334
-
Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles
-
Kanduri M, Marincevic M, Halldorsdottir AM, et al. Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles. Epigenetics 2012; 7:1435-1442.
-
(2012)
Epigenetics
, vol.7
, pp. 1435-1442
-
-
Kanduri, M.1
Marincevic, M.2
Halldorsdottir, A.M.3
-
35
-
-
77957370748
-
Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact
-
Tong WG, Wierda WG, Lin E, et al. Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact. Epigenetics 2010; 5:499-508.
-
(2010)
Epigenetics
, vol.5
, pp. 499-508
-
-
Tong, W.G.1
Wierda, W.G.2
Lin, E.3
-
36
-
-
84874347712
-
Uncovering the DNA methylome in chronic lymphocytic leukemia
-
Cahill N, Rosenquist R. Uncovering the DNA methylome in chronic lymphocytic leukemia. Epigenetics 2013; 8:138-148.
-
(2013)
Epigenetics
, vol.8
, pp. 138-148
-
-
Cahill, N.1
Rosenquist, R.2
-
37
-
-
79951499200
-
Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemia
-
Fabris S, Bollati V, Agnelli L, et al. Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemia. Epigenetics 2011; 6:188-194.
-
(2011)
Epigenetics
, vol.6
, pp. 188-194
-
-
Fabris, S.1
Bollati, V.2
Agnelli, L.3
-
38
-
-
84855854025
-
Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia
-
Rossi D, Rasi S, Fabbri G, et al. Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia. Blood 2012; 119:521-529.
-
(2012)
Blood
, vol.119
, pp. 521-529
-
-
Rossi, D.1
Rasi, S.2
Fabbri, G.3
-
39
-
-
84255160977
-
Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: Association with progression and fludarabine-refractoriness
-
Rossi D, Bruscaggin A, Spina V, et al. Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness. Blood 2011; 118:6904-6908.
-
(2011)
Blood
, vol.118
, pp. 6904-6908
-
-
Rossi, D.1
Bruscaggin, A.2
Spina, V.3
-
40
-
-
84877635463
-
NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome
-
Villamor N, Conde L, Martinez-Trillos A, et al. NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome. Leukemia 2013; 27:1100-1106.
-
(2013)
Leukemia
, vol.27
, pp. 1100-1106
-
-
Villamor, N.1
Conde, L.2
Martinez-Trillos, A.3
-
41
-
-
84855860383
-
NOTCH1 mutations in CLL associated with trisomy
-
Balatti V, Bottoni A, Palamarchuk A, et al. NOTCH1 mutations in CLL associated with trisomy Blood 2012; 119:329-331.
-
(2012)
Blood
, vol.119
, pp. 329-331
-
-
Balatti, V.1
Bottoni, A.2
Palamarchuk, A.3
-
42
-
-
84857739865
-
NOTCH1 mutations in Ã12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of Ã12 CLL
-
Del Giudice I, Rossi D, Chiaretti S, et al. NOTCH1 mutations in Ã12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of Ã12 CLL. Haematologica 2012; 97:437-441.
-
(2012)
Haematologica
, vol.97
, pp. 437-441
-
-
Del Giudice, I.1
Rossi, D.2
Chiaretti, S.3
-
43
-
-
84863580564
-
Different distribution of NOTCH1 mutations in chronic lymphocytic leukemia with isolated trisomy 12 or associated with other chromosomal alterations
-
Lopez C, Delgado J, Costa D, et al. Different distribution of NOTCH1 mutations in chronic lymphocytic leukemia with isolated trisomy 12 or associated with other chromosomal alterations. Genes Chromosomes Cancer 2012; 51:881-889.
-
(2012)
Genes Chromosomes Cancer
, vol.51
, pp. 881-889
-
-
Lopez, C.1
Delgado, J.2
Costa, D.3
-
44
-
-
84863833162
-
Different impact of NOTCH1 and SF3B1 mutations on the risk of chronic lymphocytic leukemia transformation to Richter syndrome
-
Rossi D, Rasi S, Spina V, et al. Different impact of NOTCH1 and SF3B1 mutations on the risk of chronic lymphocytic leukemia transformation to Richter syndrome. Br J Haematol 2012; 158:426-429.
-
(2012)
Br J Haematol
, vol.158
, pp. 426-429
-
-
Rossi, D.1
Rasi, S.2
Spina, V.3
-
45
-
-
84872469222
-
The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial
-
Oscier DG, Rose-Zerilli MJ, Winkelmann N, et al. The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial. Blood 2013; 121:468-475
-
(2013)
Blood
, vol.121
, pp. 468-475
-
-
Oscier, D.G.1
Rose-Zerilli, M.J.2
Winkelmann, N.3
-
46
-
-
84860705573
-
Characteristics of chronic lymphocytic leukemia with somatically acquired mutations in NOTCH1 exon
-
Shedden K, Li Y, Ouillette P, et al. Characteristics of chronic lymphocytic leukemia with somatically acquired mutations in NOTCH1 exon. Leukemia 2012; 26:1108-1110.
-
(2012)
Leukemia
, vol.26
, pp. 1108-1110
-
-
Shedden, K.1
Li, Y.2
Ouillette, P.3
-
47
-
-
84858859064
-
Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukaemia
-
Identification of BIRC3 as a recurrent mutation in CLL associated with chemorefractoriness
-
Rossi D, Fangazio M, Rasi S, et al. Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia. Blood 2012; 119:2854-2862. Identification of BIRC3 as a recurrent mutation in CLL associated with chemorefractoriness.
-
(2012)
Blood
, vol.119
, pp. 2854-2862
-
-
Rossi, D.1
Fangazio, M.2
Rasi, S.3
-
48
-
-
84878551940
-
POT1 mutations cause telomere dysfunction in chronic lymphocytic leukaemia
-
Functional characterization of POT1 mutations, the first gene of the shelterin complex identified mutated in cancer. The mutations found in CLL cause telomere fragility
-
Ramsay AJ, Quesada V, Foronda M, et al. POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia. Nat Genet 2013; 45:526-530. Functional characterization of POT1 mutations, the first gene of the shelterin complex identified mutated in cancer. The mutations found in CLL cause telomere fragility.
-
(2013)
Nat Genet
, vol.45
, pp. 526-530
-
-
Ramsay, A.J.1
Quesada, V.2
Foronda, M.3
-
49
-
-
84877894013
-
Functional analysis of sucraseisomaltase mutations from chronic lymphocytic leukemia patients
-
Rodriguez D, Ramsay AJ, Quesada V, et al. Functional analysis of sucraseisomaltase mutations from chronic lymphocytic leukemia patients. Hum Mol Genet 2013.
-
Hum Mol Genet 2013
-
-
Rodriguez, D.1
Ramsay, A.J.2
Quesada, V.3
-
50
-
-
84866870458
-
The down-regulation of miR-125b in chronic lymphocytic leukemias leads to metabolic adaptation of cells to a transformed state
-
Tili E, Michaille JJ, Luo Z, et al. The down-regulation of miR-125b in chronic lymphocytic leukemias leads to metabolic adaptation of cells to a transformed state. Blood 2012; 120:2631-2638.
-
(2012)
Blood
, vol.120
, pp. 2631-2638
-
-
Tili, E.1
Michaille, J.J.2
Luo, Z.3
-
51
-
-
84864071185
-
Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia
-
Claus R, Lucas DM, Stilgenbauer S, et al. Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia. J Clin Oncol 2012; 30:2483-2491.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2483-2491
-
-
Claus, R.1
Lucas, D.M.2
Stilgenbauer, S.3
-
52
-
-
79952389811
-
Methylation markers identify high risk patients in IGHV mutated chronic lymphocytic leukemia
-
Irving L, Mainou-Fowler T, Parker A, et al. Methylation markers identify high risk patients in IGHV mutated chronic lymphocytic leukemia. Epigenetics 2011; 6:300-306.
-
(2011)
Epigenetics
, vol.6
, pp. 300-306
-
-
Irving, L.1
Mainou-Fowler, T.2
Parker, A.3
-
54
-
-
84870502798
-
Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia
-
Lapalombella R, Sun Q, Williams K, et al. Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia. Blood 2012; 120:4621-4634.
-
(2012)
Blood
, vol.120
, pp. 4621-4634
-
-
Lapalombella, R.1
Sun, Q.2
Williams, K.3
-
55
-
-
84874652133
-
The evolutionary biography of chronic lymphocytic leukemia
-
Puente XS, Lopez-Otin C. The evolutionary biography of chronic lymphocytic leukemia. Nat Genet 2013; 45:229-231.
-
(2013)
Nat Genet
, vol.45
, pp. 229-231
-
-
Puente, X.S.1
Lopez-Otin, C.2
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