Evaluating the effect of lycopene from Lycopersicum esculentum on apoptosis during NDEA induced hepatocarcinogenesis

Biochemical and Biophysical Research Communications

Volumn 434, Issue 3, 2013, Pages 479-485

  Gupta, Prachi ^a   Bansal, Mohinder Pal ^a   Koul, Ashwani ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Apoptosis; Hepatocarcinogenesis; Lycopene; N nitrosodiethylamine; Redox environment

Indexed keywords

CASPASE 3; CASPASE 9; DIETHYLNITROSAMINE; GLUTATHIONE; LYCOPENE; MESSENGER RNA; OLIVE OIL; PROTEIN BCL 2; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; COMET ASSAY; COMPARATIVE STUDY; CONTROLLED STUDY; DNA DAMAGE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; LIPID PEROXIDATION; LIVER; LIVER CARCINOGENESIS; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOMATO; GENE; GENE EXPRESSION; RAT;

ANIMALIA; LYCOPERSICON ESCULENTUM; MUS;

EID: 84880205200     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.03.099     Document Type: Article

References (40)

1. S. Bharati, P. Rishi, A. Koul, Azadirachta indica exhibits chemopreventive action against hepatic cancer: studies on associated histopathological and ultrastructural changes, Microsc. Res. Tech. 75 (2012) 586-595.
2. K. Kawajiri, Y. Fujii-Kuriyama, P450 and human cancer, Jpn. J. Cancer Res. 82 (2005) 1325-1335.
3. A. Jemal, F. Bray, J. Ferlay, E. Ward, D. Forman, Global cancer statistics, CA Cancer J. Clin. 61 (2011) 69-90.
4. S.C. Ganger, R. Sandhir, A. Koul, Anti-clastogenic activity of Azadirachta indica against benzo(a)pyrene in murine forestomach tumorigenesis bioassay, Acta Pol. Pharm. 67 (2010) 381-390.
5. Y. Wang, L.M. Ausman, A.S. Greenberg, R.M. Russell, X.D. Wang, Dietary lycopene and tomato extract supplementations inhibit non-alcoholic steatohepatitis-promoted hepatocarcinogenesis in rats, Int. J. Cancer 15 (2010) 1788-1796.
6. S.K. Clinton, Lycopene: chemistry, biology, and implications for human health and disease, Nutr. Rev. 56 (1998) 35-51.
7. A. Koul, N. Arora, L. Tanwar, Lycopene mediated modulation of 7,12 dimethylbenz(A)anthracene induced hepatic clastogenicity in male Balb/c mice, Nutr. Hosp. 5 (2010) 304-310.
8. D. Heber, Q.Y. Lu, Overview of mechanisms of action of lycopene, Exp. Biol. Med. 227 (2002) 920-923.
9. G. Riccioni, B. Mancini, E. Di Ilio, T. Bucciarelli, N. D'Orazio, Protective effect of lycopene in cardiovascular disease, Eur. Rev. Med. Pharmacol. Sci. 12 (2008) 183-190.
10. S. Seren, R. Liberman, U.D. Bayraktar, E. Heath, K. Sahin, F. Andic, O. Kucuk, Lycopene in cancer prevention and treatment, Am. J.Ther. 15 (2008) 66-81.
11. Y. Dai, T.S. Lawrence, L. Xu, Overcoming cancer therapy resistance by targeting inhibitors of apoptosis proteins and nuclear factor-kappa B, Am. J. Transl. Res. 1 (2009) 1-15.
12. S. Fulda, Evasion of apoptosis as a cellular stress response in cancer, Int. J. Cell Biol. (2010) 370835.
13. P. Gupta, M.P. Bansal, A. Koul, Spectroscopic characterization of lycopene extract from Lycopersicum esculentum (tomato) and its evaluation as a chemopreventive agent against experimental hepatocarcinogenesis in mice, Phytother. Res. (2012), http://dx.doi.org/10.1002/ptr.4741.
14. R.R. Tice, E. Agurell, D. Anderson, B. Burlinson, A. Hartmann, H. Kobayashi, Y. Miyamae, E. Rojas, J.C. Ryu, Y.F. Sasaki, Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing, Environ. Mol. Mutagen. 35 (2000) 206-221.
15. P. Moldeus, J. Hogberg, S. Orrenius, Isolation and use of liver cells, Methods Enzymol. 52 (1978) 60-71.
16. N. Arora, A. Koul, M.P. Bansal, Chemopreventive activity of Azadirachta indica on two-stage skin carcinogenesis in murine model, Phytother. Res. 25 (2011) 408-416.
17. E.D. Wills, Mechanism of lipid peroxide formation in animal tissue, J. Biochem. 99 (1966) 667-676.
18. W.L. Zahler, W.W. Cleland, A specific and sensitive assay for disulfides, J. Biol. Chem. 243 (1968) 716-719.
19. M.S. Moron, J.W. Depierre, B. Mannervik, Levels of glutathione, glutathione reductase and glutathione Stransferase activities in rat lung and liver, Biochem. Biophys. Acta 582 (1979) 67-78.
20. A.K. Bansal, M. Bansal, G. Soni, D. Bhatnagar, Protective role of vitamin E pretreatment on N-nitrosodiethylamine induced oxidative stress in rat liver, Chem. Biol. Interact. 156 (2005) 101-111.
21. H. Salman, M. Bergman, M. Djaldetti, H. Bessler, Lycopene affects proliferation and apoptosis of four malignant cell lines, Biomed. Pharmacother. 61 (2007) 366-369.
22. S.M. Shaarawy, A.A. Tohamy, S.M. Elgendy, Z.Y.A. Elmageed, A. Bahnasy, M.S. Mohamed, E. Kandil, K. Matrougui, Protective effects of garlic and silymarin on NDEA induced rats hepatoxicity, Int. J. Biol. Sci. 5 (2009) 549-557.
23. S.Y. Sun, Apoptosis induction by chemopreventive agents, Drug News Perspect. 14 (2001) 75-80.
24. L. Verna, J. Whysner, G.M. Williams, N-Nitrodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation, Pharmacol. Ther. 71 (1996) 57-81.
25. H. Salman, M. Bergam, M. Djaldetti, H. Bessler, Lycopene affects proliferation and apoptosis of four malignant cell lines, Biomed. Pharmacother. 62 (2007) 579-582.
26. C.L. Zhang, T. Zeng, X.L. Zhao, L.H. Yu, Z.P. Zhu, K.Q. Xie, Protective effects of garlic oil on hepatocarcinoma induced by N-Nitrosodiethylamine in rats, Int. J. Biol. Sci. 8 (2012) 363-374.
27. H. Zhang, E. Kotake-Nara, H. Ono, A. Nagao, A novel cleavage product formed by autoxidation of lycopene induces apoptosis in hl-60 cells, Free Radic. Biol. Med. 35 (2003) 1653-1663.
28. C. Liu, R.M. Russell, X.D. Wang, Lycopene supplementation prevents smokeinduced changes in p53, P53 phosphorylation, cell proliferation, and apoptosis in the gastric mucosa of ferrets, J. Nutr. 136 (2005) 106-111.
29. V.R. Vasquez-Garzon, J. Arellanes-Robledo, R. Garcia-Roman, D.I. Aparicio-Rautistia, S. Villa-Trevino, Inhibition of reactive oxygen species and preneoplastic le-sions by quercetin through an antioxidant defense mechanism, Free Radic. Res. 43 (2009) 128-137.
30. L.L. de Zwart, J.H. Meerman, J.N. Commandeur, N.P. Vermeulen, Biomarkers of free radical damage applications in experimental animals and in humans, Free Radic. Biol. Med. 26 (1999) 202-226.
31. P.V. Jeyabal, M.B. Syed, M. Venkataraman, J.K. Sambandham, D. Sakthisekaran, Apigenin inhibits oxidative stress-induced macromolecular damage in Nnitrosodiethylamine (NDEA)-induced hepatocellular carcinogenesis in Wistar albino rats Mol, Carcinogenesis 44 (2005) 11-20.
32. K. Pradeep, C.V. Mohan, K. Gobianand, S. Karthiken, Silymarin modulates the oxidant-antioxidant imbalance during diethylnitrosamine induced oxidative stress in rats, Eur. J. Pharmacol. 560 (2007) 110-116.
33. P. Astrog, S. Gradelet, R. Berges, M. Suschetet, Dietary lycopene decreases the initiation of liver preneoplastic foci by diethylnitrosamine in the rat, Nutr. Cancer 29 (1997) 60-68.
34. R.M. Kluck, E. Bossy-Wetzel, D.R. Green, D.D. Newmeyer, The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis, Science 275 (1997) 1132-1136.
35. A.K. Zimmermann, F.A. Loucks, E.K. Schroeder, R.J. Bouchard, K.L. Tyler, D.A. Linseman, Glutathione binding to the Bcl-2 homology-3 domain groove: a molecular basis for Bcl-2 antioxidant function at mitochondria, J. Biol. Chem. 282 (2007) 29296-29304.
36. C. Grimm, A. Wenzel, F. Hafezi, C.E. Reme, Gene expression in the mouse retina: the effect of damaging light, Mol. Vis. 6 (2000) 252-260.
37. X. Huang, L.D. Hazlett, Analysis of Pseudomonas aeruginosa corneal infection using an oligonucleotide, Invest. Ophthalmol. Vis. Sci. 44 (2003) 3409-3416.
38. B. Levine, Q. Huang, J.T. Isaacs, J.C. Reed, D.E. Griffin, J.M. Hardwick, Conversion of lytic to persistant alphavirus infection by the bcl-2 cellular oncogene, Nature 361 (1993) 739-742.
39. B.P. Chew, M.B. Cynthia, S.P. Jean, F.M. Philip, Dietary lutein inhibits mouse mammary tumor growth by regulating angiogenesis and apoptosis, Anticancer Res. 23 (2003) 333-334.
40. K. Yamada, N. Takane-Gyotoku, X. Yuan, F. Ichikawa, C. Inada, K. Nonaka, Mouse islet cell lysis mediated by interlukein-1-induced Fas, Diabetologia 39 (1996) 1306-1312.