The cigarette smoke constituent benzo[a]pyrene disrupts metabolic enzyme, and apoptosis pathway member gene expression in ovarian follicles

Reproductive Toxicology

Volumn 40, Issue , 2013, Pages 52-59

  Sadeu, Jean Clair ^a   Foster, Warren G ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Benzo a pyrene; Folliculogenesis; Ovary; PAHs; Polyhalogenated hydrocarbons; Toxicology

Indexed keywords

AROMATASE; AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; CIGARETTE SMOKE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; HEAT SHOCK PROTEIN 90; MESSENGER RNA; PROTEIN BAX;

ANIMAL TISSUE; APOPTOSIS; APOPTOTIC GENE; AROMATASE GENE; ARTICLE; ARYL HYDROCARBON RECEPTOR GENE; ARYL HYDROXYLASE STEROIDOGENIC ENZYME GENE; CCND2 GENE; CDK2 GENE; CDK4 GENE; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOCHROME P450 1A1 GENE; FEMALE; GENE; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; GROWTH INHIBITION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARY FOLLICLE; QUANTITATIVE ANALYSIS; RNA SEQUENCE; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; STAR GENE;

BENZO[A]PYRENE; FOLLICULOGENESIS; OVARY; PAHS; POLYHALOGENATED HYDROCARBONS; TOXICOLOGY;

ANIMALS; APOPTOSIS; ARYL HYDROCARBON HYDROXYLASES; BCL-2-ASSOCIATED X PROTEIN; BENZO(A)PYRENE; CYTOCHROME P-450 CYP1A1; FEMALE; GENE EXPRESSION REGULATION; HSP90 HEAT-SHOCK PROTEINS; MICE; OVARIAN FOLLICLE; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; SMOKE; TOBACCO;

EID: 84880143367     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2013.05.008     Document Type: Article

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