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Volumn 5, Issue 11, 2010, Pages

Decreased Ratio of Treg Cells to Th17 Cells Correlates with HBV DNA Suppression in Chronic Hepatitis B Patients Undergoing Entecavir Treatment

Author keywords

[No Author keywords available]

Indexed keywords

ENTECAVIR; HEPATITIS B CORE ANTIGEN; HEPATITIS B(E) ANTIGEN; INTERLEUKIN 17; ALANINE AMINOTRANSFERASE; ANTIVIRUS AGENT; DRUG DERIVATIVE; GUANINE; VIRUS DNA;

EID: 78249257780     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013869     Document Type: Article
Times cited : (80)

References (32)
  • 1
    • 14944375587 scopus 로고    scopus 로고
    • Immunology of hepatitis B virus and hepatitis C virus infection
    • Rehermann B, Nascimbeni M (2005) Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol 5: 215-229.
    • (2005) Nat Rev Immunol , vol.5 , pp. 215-229
    • Rehermann, B.1    Nascimbeni, M.2
  • 2
    • 35348838379 scopus 로고    scopus 로고
    • Clinical immune characterization of hepatitis B virus infection and implications for immune intervention: Progress and challenges
    • Wang FS (2007) Clinical immune characterization of hepatitis B virus infection and implications for immune intervention: progress and challenges. Hepatol Res 37: S339-346.
    • (2007) Hepatol Res , vol.37
    • Wang, F.S.1
  • 3
    • 70449724811 scopus 로고    scopus 로고
    • Host immunity influences disease progression and antiviral efficacy in humans infected with hepatitis B virus
    • Wang FS, Zhang Z (2009) Host immunity influences disease progression and antiviral efficacy in humans infected with hepatitis B virus. Expert Rev Gastroenterol Hepatol 3: 499-512.
    • (2009) Expert Rev Gastroenterol Hepatol , vol.3 , pp. 499-512
    • Wang, F.S.1    Zhang, Z.2
  • 4
    • 54849146600 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Dienstag JL (2008) Hepatitis B virus infection. N Engl J Med 359: 1486-1500.
    • (2008) N Engl J Med , vol.359 , pp. 1486-1500
    • Dienstag, J.L.1
  • 5
    • 77950681821 scopus 로고    scopus 로고
    • Differential effects of interferon and lamivudine on serum HBV RNA inhibition in patients with chronic hepatitis B
    • Huang YW, Chayama K, Tsuge M, Takahashi S, Hatakeyama T, et al. (2010) Differential effects of interferon and lamivudine on serum HBV RNA inhibition in patients with chronic hepatitis B. Antivir Ther 15: 177-184.
    • (2010) Antivir Ther , vol.15 , pp. 177-184
    • Huang, Y.W.1    Chayama, K.2    Tsuge, M.3    Takahashi, S.4    Hatakeyama, T.5
  • 6
    • 2442484053 scopus 로고    scopus 로고
    • +regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • +regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 22: 531-562.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 7
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver CT, Hatton RD, Mangan PR, Harrington LE (2007) IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol 25: 821-852.
    • (2007) Annu Rev Immunol , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 8
    • 0029957570 scopus 로고    scopus 로고
    • Impact of complete inhibition of viral replication on the cellular immune response in chronic hepatitis B virus infection
    • Marinos G, Naoumov NV, Williams R (1996) Impact of complete inhibition of viral replication on the cellular immune response in chronic hepatitis B virus infection. Hepatology 24: 991-995.
    • (1996) Hepatology , vol.24 , pp. 991-995
    • Marinos, G.1    Naoumov, N.V.2    Williams, R.3
  • 9
    • 17744383748 scopus 로고    scopus 로고
    • Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B: New perspectives for immune therapy
    • Boni C, Penna A, Ogg GS, Bertoletti A, Pilli M, et al. (2001) Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B: new perspectives for immune therapy. Hepatology 33: 963-971.
    • (2001) Hepatology , vol.33 , pp. 963-971
    • Boni, C.1    Penna, A.2    Ogg, G.S.3    Bertoletti, A.4    Pilli, M.5
  • 10
    • 16244385911 scopus 로고    scopus 로고
    • Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection
    • Stoop JN, van der Molen RG, Baan CC, van der Laan LJ, Kuipers EJ, et al. (2005) Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection. Hepatology 41: 771-778.
    • (2005) Hepatology , vol.41 , pp. 771-778
    • Stoop, J.N.1    van der Molen, R.G.2    Baan, C.C.3    van der Laan, L.J.4    Kuipers, E.J.5
  • 11
    • 33745323050 scopus 로고    scopus 로고
    • +regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B
    • +regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B. J Immunol 177: 739-747.
    • (2006) J Immunol , vol.177 , pp. 739-747
    • Xu, D.1    Fu, J.2    Jin, L.3    Zhang, H.4    Zhou, C.5
  • 12
    • 36148986445 scopus 로고    scopus 로고
    • Induction of regulatory T-cells and interleukin-10-producing cells in nonresponders to pegylated interferon-alpha therapy for chronic hepatitis B
    • Sprengers D, Stoop JN, Binda RS, Kusters JG, Haagmans BL, et al. (2007) Induction of regulatory T-cells and interleukin-10-producing cells in nonresponders to pegylated interferon-alpha therapy for chronic hepatitis B. Antivir Ther 12: 1087-1096.
    • (2007) Antivir Ther , vol.12 , pp. 1087-1096
    • Sprengers, D.1    Stoop, J.N.2    Binda, R.S.3    Kusters, J.G.4    Haagmans, B.L.5
  • 13
    • 34047266620 scopus 로고    scopus 로고
    • Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B
    • Stoop JN, van der Molen RG, Kuipers EJ, Kusters JG, Janssen HL (2007) Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B. Virology 361: 141-148.
    • (2007) Virology , vol.361 , pp. 141-148
    • Stoop, J.N.1    van der Molen, R.G.2    Kuipers, E.J.3    Kusters, J.G.4    Janssen, H.L.5
  • 15
    • 73449125874 scopus 로고    scopus 로고
    • +T cells increase with severity of liver damage in patients with chronic hepatitis B
    • +T cells increase with severity of liver damage in patients with chronic hepatitis B. Hepatology 51: 81-91.
    • (2010) Hepatology , vol.51 , pp. 81-91
    • Zhang, J.Y.1    Zhang, Z.2    Lin, F.3    Zou, Z.S.4    Xu, R.N.5
  • 16
    • 32244442562 scopus 로고    scopus 로고
    • TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B (2006) TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24: 179-189.
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 17
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells
    • Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, et al. (2006) Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells. Nature 441: 235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5
  • 18
    • 43449135305 scopus 로고    scopus 로고
    • TGF-betainduced FoxP3 inhibits TH17 cell differentiation by antagonizing RORct function
    • Zhou L, Lopes JE, Chong MM, Ivanov II, Min R, et al. (2008) TGF-betainduced FoxP3 inhibits TH17 cell differentiation by antagonizing RORct function. Nature 453: 236-240.
    • (2008) Nature , vol.453 , pp. 236-240
    • Zhou, L.1    Lopes, J.E.2    Chong, M.M.3    Ivanov, I.I.4    Min, R.5
  • 19
    • 77949655510 scopus 로고    scopus 로고
    • Efficacy and resistance of entecavir following 3 years of treatment of Japanese patients with lamivudine-refractory chronic hepatitis B
    • Karino Y, Toyota J, Kumada H, Katano Y, Izumi N, et al. (2010) Efficacy and resistance of entecavir following 3 years of treatment of Japanese patients with lamivudine-refractory chronic hepatitis B. Hepatol Int 4: 414-422.
    • (2010) Hepatol Int , vol.4 , pp. 414-422
    • Karino, Y.1    Toyota, J.2    Kumada, H.3    Katano, Y.4    Izumi, N.5
  • 20
    • 77952430906 scopus 로고    scopus 로고
    • Long-term use of entecavir in nucleoside-naïve Japanese patients with chronic hepatitis B infection
    • Yokosuka O, Takaguchi K, Fujioka S, Shindo M, Chayama K, et al. (2010) Long-term use of entecavir in nucleoside-naïve Japanese patients with chronic hepatitis B infection. J Hepatol 52: 791-799.
    • (2010) J Hepatol , vol.52 , pp. 791-799
    • Yokosuka, O.1    Takaguchi, K.2    Fujioka, S.3    Shindo, M.4    Chayama, K.5
  • 21
    • 72249122581 scopus 로고    scopus 로고
    • Evolution of hepatitis B virus mutation during entecavir rescue therapy in patients with antiviral resistance to lamivudine and adefovir
    • Choe WH, Hong SP, Kim BK, Ko SY, Jung YK, et al. (2009) Evolution of hepatitis B virus mutation during entecavir rescue therapy in patients with antiviral resistance to lamivudine and adefovir. Antivir Ther 14: 985-993.
    • (2009) Antivir Ther , vol.14 , pp. 985-993
    • Choe, W.H.1    Hong, S.P.2    Kim, B.K.3    Ko, S.Y.4    Jung, Y.K.5
  • 22
    • 69849090825 scopus 로고    scopus 로고
    • Rescue monotherapy in lamivudine-resistant hepatitis B e antigen-positive chronic hepatitis B: Adefovir versus entecavir
    • Lee JM, Kim HJ, Park JY, Lee CK, Kim do Y, et al. (2009) Rescue monotherapy in lamivudine-resistant hepatitis B e antigen-positive chronic hepatitis B: adefovir versus entecavir. Antivir Ther 14: 705-712.
    • (2009) Antivir Ther , vol.14 , pp. 705-712
    • Lee, J.M.1    Kim, H.J.2    Park, J.Y.3    Lee, C.K.4    do Kim, Y.5
  • 24
    • 0032169470 scopus 로고    scopus 로고
    • Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B
    • Boni C, Bertoletti A, Penna A, Cavalli A, Pilli M, et al. (1998) Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B. J Clin Invest 102: 968-975.
    • (1998) J Clin Invest , vol.102 , pp. 968-975
    • Boni, C.1    Bertoletti, A.2    Penna, A.3    Cavalli, A.4    Pilli, M.5
  • 25
    • 12444252951 scopus 로고    scopus 로고
    • Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B
    • Boni C, Penna A, Bertoletti A, Lamonaca V, Rapti I, et al. (2003) Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B. J Hepatol 39: 595-605.
    • (2003) J Hepatol , vol.39 , pp. 595-605
    • Boni, C.1    Penna, A.2    Bertoletti, A.3    Lamonaca, V.4    Rapti, I.5
  • 26
    • 33947729690 scopus 로고    scopus 로고
    • Interleukin-17 as a new marker of severity of acute hepatic injury
    • Yasumi Y, Takikawa Y, Endo R, Suzuki K (2007) Interleukin-17 as a new marker of severity of acute hepatic injury. Hepatol Res 37: 248-254.
    • (2007) Hepatol Res , vol.37 , pp. 248-254
    • Yasumi, Y.1    Takikawa, Y.2    Endo, R.3    Suzuki, K.4
  • 27
    • 61949356502 scopus 로고    scopus 로고
    • The interleukin-17 pathway is involved in human alcoholic liver disease
    • Lemmers A, Moreno C, Gustot T, Maréchal R, Degré D, et al. (2008) The interleukin-17 pathway is involved in human alcoholic liver disease. Hepatology 49: 646-657.
    • (2008) Hepatology , vol.49 , pp. 646-657
    • Lemmers, A.1    Moreno, C.2    Gustot, T.3    Maréchal, R.4    Degré, D.5
  • 28
    • 58149311503 scopus 로고    scopus 로고
    • Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta
    • Rowan AG, Fletcher JM, Ryan EJ, Moran B, Hegarty JE, et al. (2008) Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta. J Immunol 181: 4485-4494.
    • (2008) J Immunol , vol.181 , pp. 4485-4494
    • Rowan, A.G.1    Fletcher, J.M.2    Ryan, E.J.3    Moran, B.4    Hegarty, J.E.5
  • 30
    • 77953255484 scopus 로고    scopus 로고
    • The cytokine milieu in the interplay of pathogenic Th1/Th17 cells and regulatory T cells in autoimmune disease
    • Leung S, Liu X, Fang L, Chen X, Guo T, et al. (2010) The cytokine milieu in the interplay of pathogenic Th1/Th17 cells and regulatory T cells in autoimmune disease. Cell Mol Immunol 7: 182-189.
    • (2010) Cell Mol Immunol , vol.7 , pp. 182-189
    • Leung, S.1    Liu, X.2    Fang, L.3    Chen, X.4    Guo, T.5
  • 31
    • 35649018292 scopus 로고    scopus 로고
    • Interplay between pathogenic Th17 and regulatory T cells
    • Oukka M (2007) Interplay between pathogenic Th17 and regulatory T cells. Ann Rheum Dis 66: iii87-90.
    • (2007) Ann Rheum Dis , vol.66
    • Oukka, M.1
  • 32
    • 72949106340 scopus 로고    scopus 로고
    • Interplay between the Th17 and Treg cell lineages: A (co-)evolutionary perspective
    • Weaver CT, Hatton RD (2009) Interplay between the Th17 and Treg cell lineages: a (co-)evolutionary perspective. Nat Rev Immunol 9: 883-889.
    • (2009) Nat Rev Immunol , vol.9 , pp. 883-889
    • Weaver, C.T.1    Hatton, R.D.2


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