Antidiabetic, Antihyperlipidemic and Antioxidant Activities of a Novel Proteoglycan from Ganoderma Lucidum Fruiting Bodies on db/db Mice and the Possible Mechanism

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Pan, Deng ^a   Zhang, Dang ^b   Wu, Jiasheng ^b   Chen, Congheng ^a   Xu, Zhixue ^a   Yang, Hongjie ^b   Zhou, Ping ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ANTIDIABETIC AGENT; ANTIOXIDANT; C PEPTIDE; CATALASE; FUDAN YUEYANG GANODERMA LUCIDUM; GLUCOKINASE; GLUCOSE TRANSPORTER 2; GLUCOSE TRANSPORTER 4; GLUTATHIONE PEROXIDASE; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C; INSULIN; MALONALDEHYDE; METFORMIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ANTIHYPERLIPIDEMIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; DRUG ACTIVITY; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVITY; FRUITING BODY; GANODERMA LUCIDUM; GLUCAGON BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN SENSITIVITY; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS FUNCTION; PANCREAS ISLET; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; ANTIOXIDANTS; BIOLOGICAL FACTORS; BLOOD GLUCOSE; C-PEPTIDE; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GLUCOKINASE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 2; GLUCOSE TRANSPORTER TYPE 4; HEMOGLOBIN A, GLYCOSYLATED; HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; INSULIN; INSULIN RESISTANCE; ISLETS OF LANGERHANS; LIVER; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; OXIDATIVE STRESS; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PROTEOGLYCANS; REISHI;

EID: 84880078678     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068332     Document Type: Article

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