Structural characterization of carbohydrate binding by LMAN1 protein provides new insight into the endoplasmic reticulum export of factors V (FV) and VIII (FVIII)

Journal of Biological Chemistry

Volumn 288, Issue 28, 2013, Pages 20499-20509

  Zheng, Chunlei ^a   Page, Richard C ^a   Das, Vaijayanti ^a   Nix, Jay C ^b   Wigren, Edvard ^c   Misra, Saurav ^a   Zhang, Bin ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING AND RELEASE; CARBOHYDRATE BINDING; CARBOHYDRATE-RECOGNITION DOMAINS; COAGULATION FACTOR; ENDOPLASMIC RETICULUM; SECRETORY PATHWAYS; SOLVED CRYSTAL STRUCTURES; STRUCTURAL CHARACTERIZATION;

AMINO ACIDS; BINDING SITES; CALCIUM; CARBOHYDRATES; GLYCOPROTEINS; MAMMALS;

CELL MEMBRANES;

BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 8; CALCIUM ION; CARBOHYDRATE; ENDOPLASMIC RETICULUM GOLGI INTERMEDIATE COMPARTMENT PROTEIN 53; GLUCORECEPTOR; GLYCINE; HISTIDINE; MANNOSE; PROTEIN MCFD2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING KINETICS; CALCIUM CELL LEVEL; CARBOHYDRATE ANALYSIS; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; IN VITRO STUDY; LECTIN BINDING SITE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REGULATORY MECHANISM; STRUCTURE ANALYSIS;

CALCIUM-BINDING PROTEINS; CARBOHYDRATE-BINDING PROTEIN; COAGULATION FACTORS; ENDOPLASMIC RETICULUM (ER); ERGIC; GOLGI; HEMORRHAGIC DISORDERS; HEMOSTASIS; MEMBRANE TRAFFICKING; PROTEIN SECRETION;

ANIMALS; BINDING SITES; BLOTTING, WESTERN; CALCIUM; CARBOHYDRATE SEQUENCE; CERCOPITHECUS AETHIOPS; COS CELLS; CRYSTALLOGRAPHY, X-RAY; ENDOPLASMIC RETICULUM; FACTOR V; FACTOR VIII; GLYCINE; GOLGI APPARATUS; HISTIDINE; HUMANS; MANNOSE; MANNOSE-BINDING LECTINS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; VESICULAR TRANSPORT PROTEINS;

EID: 84880070996     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.461434     Document Type: Article

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