The lectin ERGIC-53 is a cargo transport receptor for glycoproteins

Nature Cell Biology

Volumn 1, Issue 6, 1999, Pages 330-334

  Appenzeller, Christian ^a   Andersson, Helena ^a,b   Kappeler, Felix ^a   Hauri, Hans Peter ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b Novum Research Center   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; CATHEPSIN; CATHEPSIN K; GLYCOPROTEIN; LECTIN; LMAN1 PROTEIN, HUMAN; MANNOSE BINDING LECTIN; MEMBRANE PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CARBOHYDRATE METABOLISM; CELL LINE; ENDOPLASMIC RETICULUM; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; RABBIT;

AMINO ACID SEQUENCE; ANIMALS; CARBOHYDRATE METABOLISM; CARRIER PROTEINS; CATHEPSINS; CELL LINE; ENDOPLASMIC RETICULUM; GLYCOPROTEINS; HUMANS; LECTINS; MANNOSE-BINDING LECTINS; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; RABBITS;

EID: 0033202958     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/14020     Document Type: Article

References (33)

1. Schekman, R. & Orci, L. Coat proteins and vesicle budding. Science 271, 1526-1533 (1996).
2. Hauri, H.-P. & Schweizer, A. in Handbook of Physiology: Cell Physiology (eds Hoffman, J. F. & Jamieson, J. D.) 605-647 (Oxford Univ. Press, Oxford, 1997).
3. Glick, B. S. & Malhotra, V. The curious status of the Golgi apparatus. Cell 95, 883-889 (1998).
4. Bannykh, S. I. & Balch, W. E. Membrane dynamics at the endoplasmic reticulum - Golgi interface. J. Cell Biol. 138, 1-4 (1997).
5. Mitsuno, M. & Singer, S. J. A soluble secretory protein is first concentrated in the endoplasmic reticulum before transfer to the Golgi apparatus. Proc. Natl Acad. Sci. USA 90, 5732-5736 (1993).
6. Balch, W. E., McCaffery, J. M., Plutner, H. & Farquhar, M. G. Vesicular stomatitis virus glycoprotein is sorted and concentrated during export from the endoplasmic reticulum. Cell 76, 841-852 (1994).
7. Rexach, M. F., Latterich, M. & Schekman, R. W. Characteristics of endoplasmic reticulum-derived transport vesicles. J. Cell Biol. 126, 1133-1148 (1994).
8. Herrmann, J. M., Malkus, P. & Schekman, R. Out of the ER - outfitters, escorts and guides. Trends Cell Biol. 9, 5-7 (1999).
9. Klumperman, J. et al. The recycling pathway of protein ERGIC-53 and dynamics of the ER-Golgi intermediate compartment. J. Cell Sci. 111, 3411-3425 (1998).
10. Fiedler, K. & Simons, K. A putative novel class of animal lectins in the secretory pathway homologous to leguminous lectins. Cell 77, 625-626 (1994).
11. Itin, C., Roche, A. C., Monsigny, M. & Hauri, H.-P. ERGIC-53 is a functional mannose-selective and calcium-dependent human homologue of leguminous lectins. Mol. Biol. Cell 7, 483-493 (1996).
12. Kappeler, F., Klopfenstein, D., Foguet, M., Paccaud, J.-P. & Hauri, H.-P. The recycling of ERGIC-53 in the early secretory pathway. J. Biol. Chem. 272, 31801-31808 (1997).
13. Tisdale, E. J., Plutner, H., Matteson, J. & Balch, W. E. p53/p58 binds COPI and is required for selective transport through the early secretory pathway. J. Cell Biol. 137, 581-593 (1997).
14. Vollenweider, F., Kappeler, F., Itin, C. & Hauri, H.-P. Mistargeting of the lectin ERGIC-53 to the endoplasmic reticulum of HeLa cells impairs the secretion of a lysosomal enzyme. J. Cell Biol. 142, 377-389 (1998).
15. Nichols, W. C. et al. Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII. Cell 93, 61-70 (1998).
16. Schimmöller, F. et al. The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi. EMBO J. 14, 1329-1339 (1995).
17. Fiedler, K., Veit, M., Stamnes, M. A. & Rothman, J. E. Bimodal interaction of coatomer with the p24 family of putative cargo receptors. Science 273, 1396-1399 (1996).
18. Dominguez, M. et al. gp25L/emp24/p24 protein family members of the cis-Golgi network bind both COP I and II coatomer. J. Cell Biol. 140, 751-765 (1998).
19. Bremser, M. et al. Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors. Cell 96, 495-506 (1999).
20. Andersson, H., Kappeler, K. & Hauri, H.-P. Protein targeting to endoplasmic reticulum by dilysine signals involves direct retention in addition to retrieval. J. Biol Chem. 274, 15080-15084 (1999).
21. Santamaria, I., Velasco, G., Pendas, A. M., Fueyo, A. & Lopez-Otin, C. Cathepsin Z, a novel human cysteine proteinase with a short propeptide domain and a unique chromosomal location. J. Biol Chem. 273, 16816-16823 (1998).
22. Klopfenstein, D. R. C., Kappeler, F. & Hauri, H.-P. A novel direct interaction of endoplasmic reticulum with microtubules. EMBO J. 17, 6168-6177 (1998).
23. Trombetta, E. S. & Helenius, A. Lectins as chaperones in glycoprotein folding. Curr. Opin. Struct. Biol. 8, 587-592 (1998).
24. Cacan, R. & Verbert, A. Free and N-linked oligomannosides as markers of the quality control of newly synthesized glycoproteins. Biochem. Biophys. Res. Commun. 258, 1-5 (1999).
25. Lahtinen, U., Svensson, K. & Pettersson, R. F. Mapping of structural determinants for the oligomerization of p58, a lectin-like protein of the intermediate compartment and cis-Golgi. Eur. J. Biochem. 260, 392-397 (1999).
26. Zhang, T., Wong, S. H., Tang, B. L., Xu, Y. & Hong, W. Morphological and functional association of Sec22b/ERS-24 with the pre-Golgi intermediate compartment. Mol. Biol. Cell 10, 435-453 (1999).
27. Powers, J. & Barlowe, C. Transport of ax12p depends on erv14p, an ER-vesicle protein related to the Drosophila cornichon gene product. J. Cell Biol. 142, 1209-1222 (1998).
28. Schröder, S., Schimmöller, F., Singer-Krüger, B. & Riezman, H. The Golgi-localization of yeast Emp47p depends on its di-lysine motif but is not affected by the ret1-1 mutation in alpha-COP. J. Cell Biol. 131, 895-912 (1995).
29. Fiedler, K., Parton, R. G., Kellner, R., Etzold, T. & Simons, K. VIP36, a novel component of glycolipid rafts and exocytic carrier vesicles in epithelial cells. EMBO J 13, 1729-1740 (1994).
30. Hara-Kuge, S., Ohkura, T., Seko A, & Yamashita, K. Vesicular-integral membrane protein, VIP36, recognizes high-mannose type glycans containing alpha 1-2 mannosyl residues in MDCK cells. Glycobiology 9, 833-839 (1999).
31. Wieland, F. T., Gleason, M. L., Serafini, T. A. & Rothman, J. E. The rate of bulk flow from the endoplasmic reticulum to the cell surface. Cell 50, 289-300 (1987).
32. Itin, C., Schindler, R. & Hauri, H.-P. Targeting of protein ERGIC-53 to the ER/ERGIC/cis-Golgi recycling pathway. J. Cell Biol. 131, 57-67 (1995).
33. Schweizer, A., Fransen, J. A. M., Bächi, T., Ginsel L. & Hauri H.-P. Identification, by a monoclonal antibody, of a 53 kD protein associated with a tubulo-vesicular compartment at the cis-side of the Golgi apparatus. J. Cell Biol. 107, 1643-1653 (1988).