Crystal structure of the LMAN1-CRD/MCFD2 transport receptor complex provides insight into combined deficiency of factor V and factor VIII

FEBS Letters

Volumn 584, Issue 5, 2010, Pages 878-882

  Wigren, Edvard ^a   Bourhis, Jean Marie ^a   Kursula, Inari ^a   Guy, Jodie E ^a   Lindqvist, Ylva ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Crystal structure; ER quality control; ERGIC 53; Glycoprotein transport; Protein complex

Indexed keywords

BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 8; GLYCOPROTEIN; PROTEIN LMAN1; PROTEIN MCFD2; UNCLASSIFIED DRUG;

ARTICLE; BLOOD CLOTTING FACTOR 5 DEFICIENCY; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; GENE MUTATION; HEMOPHILIA A; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; PROTEIN TRANSPORT; STRUCTURE ANALYSIS;

BLOOD COAGULATION DISORDERS, INHERITED; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; FACTOR V; FACTOR V DEFICIENCY; FACTOR VIII; HUMANS; MANNOSE-BINDING LECTINS; MEMBRANE PROTEINS; MUTATION; PROTEIN STRUCTURE, SECONDARY; VESICULAR TRANSPORT PROTEINS;

EID: 76749118043     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.02.009     Document Type: Article

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