Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation

Journal of Biological Chemistry

Volumn 288, Issue 27, 2013, Pages 19958-19972

  Tashiro, Erika ^a   Zako, Tamotsu ^b   Muto, Hideki ^a   Itoo, Yoshinori ^b,c   Sörgjerd, Karin ^b   Terada, Naofumi ^a   Abe, Akira ^a   Miyazawa, Makoto ^a   Kitamura, Akira ^a   Kitaura, Hirotake ^a   Kubota, Hiroshi ^d   Maeda, Mizuo ^b   Momoi, Takashi ^e   Iguchi Ariga, Sanae M M ^a   Kinjo, Masataka ^a   Ariga, Hiroyoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b RIKEN   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d AKITA UNIVERSITY   (Japan)

^e INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENCE CORRELATION SPECTROSCOPY; HUNTINGTON DISEASE; INCLUSION FORMATION; MOLECULAR CHAPERONES; NEURONAL CELL; POLYGLUTAMINE; POLYGLUTAMINE (POLYQ); SINGLE-MOLECULE OBSERVATION;

DIMERS; FLUORESCENCE SPECTROSCOPY;

CELL DEATH;

CHAPERONE; HUNTINGTIN; POLYGLUTAMINE; PREFOLDIN; PREFOLDIN 1; PREFOLDIN 2; PREFOLDIN 3; PREFOLDIN 4; PREFOLDIN 5; PREFOLDIN 6; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; ENZYME INDUCTION; ENZYME INHIBITION; FLUORESCENCE CORRELATION SPECTROSCOPY; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; NERVE CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FUNCTION;

CELL DEATH; CHAPERONE CHAPERONIN; NEURODEGENERATION; POLYGLUTAMINE DISEASE; PROTEIN AGGREGATION;

CELL DEATH; CELL LINE, TUMOR; HUMANS; MOLECULAR CHAPERONES; NERVE TISSUE PROTEINS; NEURONS; PEPTIDES; REPRESSOR PROTEINS; SOLUBILITY;

EID: 84880070798     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.477984     Document Type: Article

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