메뉴 건너뛰기




Volumn 73, Issue 13, 2013, Pages 3951-3962

SENP1 deSUMOylates and regulates pin1 protein activity and cellular function

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDYLPROLYL ISOMERASE PIN1; SUMO PROTEASE 1; SUMO PROTEIN; UNCLASSIFIED DRUG;

EID: 84880063596     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-4360     Document Type: Article
Times cited : (71)

References (50)
  • 1
    • 80053304845 scopus 로고    scopus 로고
    • Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease
    • Lee TH, Pastorino L, Lu KP. Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease. Expert Rev Mol Med 2011;13: e21.
    • (2011) Expert Rev Mol Med , vol.13
    • Lee, T.H.1    Pastorino, L.2    Lu, K.P.3
  • 2
    • 80053299231 scopus 로고    scopus 로고
    • Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins
    • Liou YC, Zhou XZ, Lu KP. Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins. Trends Biochem Sci 2011;36: 501-14.
    • (2011) Trends Biochem Sci , vol.36 , pp. 501-514
    • Liou, Y.C.1    Zhou, X.Z.2    Lu, K.P.3
  • 3
    • 35448945269 scopus 로고    scopus 로고
    • The prolyl isomerase PIN1: A pivotal new twist in phosphorylation signalling and disease
    • Lu KP, Zhou XZ. The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease. Nat Rev Mol Cell Biol 2007; 8: 904-16.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 904-916
    • Lu, K.P.1    Zhou, X.Z.2
  • 4
    • 84859185373 scopus 로고    scopus 로고
    • Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease
    • Nakamura K, Greenwood A, Binder L, Bigio EH, Denial S, Nicholson L, et al. Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease. Cell 2012;149: 232-44.
    • (2012) Cell , vol.149 , pp. 232-244
    • Nakamura, K.1    Greenwood, A.2    Binder, L.3    Bigio, E.H.4    Denial, S.5    Nicholson, L.6
  • 5
    • 80051583598 scopus 로고    scopus 로고
    • A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression
    • Yuan WC, Lee YR, Huang SF, Lin YM, Chen TY, Chung HC, et al. A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression. Cancer Cell 2011;20: 214-28.
    • (2011) Cancer Cell , vol.20 , pp. 214-228
    • Yuan, W.C.1    Lee, Y.R.2    Huang, S.F.3    Lin, Y.M.4    Chen, T.Y.5    Chung, H.C.6
  • 7
    • 84863000735 scopus 로고    scopus 로고
    • Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase
    • Min SH, Lau AW, Lee TH, Inuzuka H, Wei S, Huang P, et al. Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase. Mol Cell 2012;46: 771-83.
    • (2012) Mol Cell , vol.46 , pp. 771-783
    • Min, S.H.1    Lau, A.W.2    Lee, T.H.3    Inuzuka, H.4    Wei, S.5    Huang, P.6
  • 8
    • 84884812052 scopus 로고    scopus 로고
    • The prolyl isomerase Pin1 interacts with and downregulates the activity of AMPK leading to induction of tumorigenicity of hepatocarcinoma cells
    • Apr 30. [Epub ahead of print].
    • Khanal P, Kim G, Yun HJ, Cho HG, Choi HS. The prolyl isomerase Pin1 interacts with and downregulates the activity of AMPK leading to induction of tumorigenicity of hepatocarcinoma cells. Mol Carcinog 2012 Apr 30. [Epub ahead of print].
    • (2012) Mol Carcinog
    • Khanal, P.1    Kim, G.2    Yun, H.J.3    Cho, H.G.4    Choi, H.S.5
  • 9
    • 84870598190 scopus 로고    scopus 로고
    • ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
    • Yang W, Zheng Y, Xia Y, Ji H, Chen X, Guo F, et al. ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect. Nat Cell Biol 2012;14: 1295-304.
    • (2012) Nat Cell Biol , vol.14 , pp. 1295-1304
    • Yang, W.1    Zheng, Y.2    Xia, Y.3    Ji, H.4    Chen, X.5    Guo, F.6
  • 10
    • 0036315162 scopus 로고    scopus 로고
    • PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cells
    • Ryo A, Liou YC, Wulf G, Nakamura M, Lee SW, Lu KP. PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cells. Mol Cell Biol 2002;22: 5281-95.
    • (2002) Mol Cell Biol , vol.22 , pp. 5281-5295
    • Ryo, A.1    Liou, Y.C.2    Wulf, G.3    Nakamura, M.4    Lee, S.W.5    Lu, K.P.6
  • 11
    • 32044460171 scopus 로고    scopus 로고
    • Pin1 regulates centrosome duplication and its overexpression induces centrosome amplification, chromosome instability and oncogenesis
    • Suizu F, Ryo A, Wulf G, Lim J, Lu KP. Pin1 regulates centrosome duplication and its overexpression induces centrosome amplification, chromosome instability and oncogenesis. Mol Cell Biol 2006;26: 1463-79.
    • (2006) Mol Cell Biol , vol.26 , pp. 1463-1479
    • Suizu, F.1    Ryo, A.2    Wulf, G.3    Lim, J.4    Lu, K.P.5
  • 12
    • 4444309643 scopus 로고    scopus 로고
    • Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis
    • Wulf G, Garg P, Liou YC, Iglehart D, Lu KP. Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis. EMBO J 2004;23: 3397-407.
    • (2004) EMBO J , vol.23 , pp. 3397-3407
    • Wulf, G.1    Garg, P.2    Liou, Y.C.3    Iglehart, D.4    Lu, K.P.5
  • 13
    • 79954456974 scopus 로고    scopus 로고
    • Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function
    • Lee TH, Chen CH, Suizu F, Huang P, Schiene-Fischer C, Daum S, et al. Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function. Mol Cell 2011;42: 147-59.
    • (2011) Mol Cell , vol.42 , pp. 147-159
    • Lee, T.H.1    Chen, C.H.2    Suizu, F.3    Huang, P.4    Schiene-Fischer, C.5    Daum, S.6
  • 14
    • 78649396592 scopus 로고    scopus 로고
    • The SUMO pathway: Emerging mechanisms that shape specificity, conjugation and recognition
    • Gareau JR, Lima CD. The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition. Nat Rev Mol Cell Biol 2010;11: 861-71.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 861-871
    • Gareau, J.R.1    Lima, C.D.2
  • 17
    • 33845696665 scopus 로고    scopus 로고
    • Genetic and functional evidence supporting SUMO4 as a type 1 diabetes susceptibility gene
    • Wang CY, Podolsky R, She JX. Genetic and functional evidence supporting SUMO4 as a type 1 diabetes susceptibility gene. Ann N Y Acad Sci 2006;1079: 257-67.
    • (2006) Ann N y Acad Sci , vol.1079 , pp. 257-267
    • Wang, C.Y.1    Podolsky, R.2    She, J.X.3
  • 18
    • 79952846685 scopus 로고    scopus 로고
    • SUMO losing balance: SUMO proteases disrupt SUMO homeostasis to facilitate cancer development and progression
    • Bawa-Khalfe T, Yeh ET. SUMO losing balance: SUMO proteases disrupt SUMO homeostasis to facilitate cancer development and progression. Genes Cancer 2010;1: 748-52.
    • (2010) Genes Cancer , vol.1 , pp. 748-752
    • Bawa-Khalfe, T.1    Yeh, E.T.2
  • 19
    • 33748525164 scopus 로고    scopus 로고
    • Role of desumoylation in the development of prostate cancer
    • Cheng J, Bawa T, Lee P, Gong L, Yeh ET. Role of desumoylation in the development of prostate cancer. Neoplasia 2006;8: 667-76.
    • (2006) Neoplasia , vol.8 , pp. 667-676
    • Cheng, J.1    Bawa, T.2    Lee, P.3    Gong, L.4    Yeh, E.T.5
  • 20
    • 35548935098 scopus 로고    scopus 로고
    • SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia
    • Cheng J, Kang X, Zhang S, Yeh ET. SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia. Cell 2007;131: 584-95.
    • (2007) Cell , vol.131 , pp. 584-595
    • Cheng, J.1    Kang, X.2    Zhang, S.3    Yeh, E.T.4
  • 21
    • 84863393395 scopus 로고    scopus 로고
    • SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation
    • Van Nguyen T, Angkasekwinai P, Dou H, Lin FM, Lu LS, Cheng J, et al. SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation. Mol Cell 2012;45: 210-21.
    • (2012) Mol Cell , vol.45 , pp. 210-221
    • Van Nguyen, T.1    Angkasekwinai, P.2    Dou, H.3    Lin, F.M.4    Lu, L.S.5    Cheng, J.6
  • 22
    • 20244380938 scopus 로고    scopus 로고
    • Two-step differential expression analysis reveals a new set of genes involved in thyroid oncocytic tumors
    • Jacques C, Baris O, Prunier-Mirebeau D, Savagner F, Rodien P, Rohmer V, et al. Two-step differential expression analysis reveals a new set of genes involved in thyroid oncocytic tumors. J Clin Endocrinol Metab 2005;90: 2314-20.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2314-2320
    • Jacques, C.1    Baris, O.2    Prunier-Mirebeau, D.3    Savagner, F.4    Rodien, P.5    Rohmer, V.6
  • 23
    • 0031438929 scopus 로고    scopus 로고
    • Sequence-specific and phosphorylation-dependent proline isomerization: A potential mitotic regulatory mechanism
    • Yaffe MB, Schutkowski M, Shen M, Zhou XZ, Stukenberg PT, Rahfeld J, et al. Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism. Science 1997;278: 1957-60.
    • (1997) Science , vol.278 , pp. 1957-1960
    • Yaffe, M.B.1    Schutkowski, M.2    Shen, M.3    Zhou, X.Z.4    Stukenberg, P.T.5    Rahfeld, J.6
  • 24
    • 84861434071 scopus 로고    scopus 로고
    • Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function
    • Rangasamy V, Mishra R, Sondarva G, Das S, Lee TH, Bakowska JC, et al. Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function. Proc Natl Acad Sci U S A 2012;109: 8149-54.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 8149-8154
    • Rangasamy, V.1    Mishra, R.2    Sondarva, G.3    Das, S.4    Lee, T.H.5    Bakowska, J.C.6
  • 25
    • 55249109587 scopus 로고    scopus 로고
    • Binding STAT2 by the acidic domain of human cytomegalovirus IE1 promotes viral growth and is negatively regulated by SUMO
    • Huh YH, Kim YE, Kim ET, Park JJ, Song MJ, Zhu H, et al. Binding STAT2 by the acidic domain of human cytomegalovirus IE1 promotes viral growth and is negatively regulated by SUMO. J Virol 2008; 82: 10444-54.
    • (2008) J Virol , vol.82 , pp. 10444-10454
    • Huh, Y.H.1    Kim, Y.E.2    Kim, E.T.3    Park, J.J.4    Song, M.J.5    Zhu, H.6
  • 26
    • 77955999636 scopus 로고    scopus 로고
    • Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif
    • Matic I, Schimmel J, Hendriks IA, van Santen MA, van de Rijke F, van Dam H, et al. Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif. Mol Cell 2010;39: 641-52.
    • (2010) Mol Cell , vol.39 , pp. 641-652
    • Matic, I.1    Schimmel, J.2    Hendriks, I.A.3    Van Santen, M.A.4    Van De Rijke, F.5    Van Dam, H.6
  • 27
    • 15444380557 scopus 로고    scopus 로고
    • Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4
    • Chang CC, Lin DY, Fang HI, Chen RH, Shih HM. Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4. J Biol Chem 2005;280: 10164-73.
    • (2005) J Biol Chem , vol.280 , pp. 10164-10173
    • Chang, C.C.1    Lin, D.Y.2    Fang, H.I.3    Chen, R.H.4    Shih, H.M.5
  • 28
    • 0008233581 scopus 로고    scopus 로고
    • Structural and functional analysis of the mitotic peptidyl-prolyl isomerase Pin1 suggests that substrate recognition is phosphorylation dependent
    • Ranganathan R, Lu KP, Hunter T, Noel JP. Structural and functional analysis of the mitotic peptidyl-prolyl isomerase Pin1 suggests that substrate recognition is phosphorylation dependent. Cell 1997;89: 875-86.
    • (1997) Cell , vol.89 , pp. 875-886
    • Ranganathan, R.1    Lu, K.P.2    Hunter, T.3    Noel, J.P.4
  • 29
    • 0347955360 scopus 로고    scopus 로고
    • Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA
    • Ryo A, Suizu F, Yoshida Y, Perrem K, Liou YC, Wulf G, et al. Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Mol Cell 2003;12: 1413-26.
    • (2003) Mol Cell , vol.12 , pp. 1413-1426
    • Ryo, A.1    Suizu, F.2    Yoshida, Y.3    Perrem, K.4    Liou, Y.C.5    Wulf, G.6
  • 30
    • 0035796405 scopus 로고    scopus 로고
    • Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1
    • Wulf GM, Ryo A, Wulf GG, Lee SW, Niu T, Petkova V, et al. Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1. EMBO J 2001;20: 3459-72.
    • (2001) EMBO J , vol.20 , pp. 3459-3472
    • Wulf, G.M.1    Ryo, A.2    Wulf, G.G.3    Lee, S.W.4    Niu, T.5    Petkova, V.6
  • 31
    • 0037205460 scopus 로고    scopus 로고
    • Association of the human SUMO-1 protease SENP2 with the nuclear pore
    • Hang J, Dasso M. Association of the human SUMO-1 protease SENP2 with the nuclear pore. J Biol Chem 2002;277: 19961-6.
    • (2002) J Biol Chem , vol.277 , pp. 19961-19966
    • Hang, J.1    Dasso, M.2
  • 32
    • 0346422441 scopus 로고    scopus 로고
    • Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1
    • Bailey D, O'Hare P. Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1. J Biol Chem 2004;279: 692-703.
    • (2004) J Biol Chem , vol.279 , pp. 692-703
    • Bailey, D.1    O'Hare, P.2
  • 33
    • 84877621274 scopus 로고    scopus 로고
    • SUMO-specific protease 1 promotes prostate cancer progression and metastasis
    • Wang Q, Xia N, Li T, Xu Y, Zou Y, Zuo Y, et al. SUMO-specific protease 1 promotes prostate cancer progression and metastasis. Oncogene 2013;32: 2493-8.
    • (2013) Oncogene , vol.32 , pp. 2493-2498
    • Wang, Q.1    Xia, N.2    Li, T.3    Xu, Y.4    Zou, Y.5    Zuo, Y.6
  • 34
    • 84861452914 scopus 로고    scopus 로고
    • A redox-regulated SUMO/acetylation switch of HIPK2 controls the survival threshold to oxidative stress
    • de la Vega L, Grishina I, Moreno R, Kruger M, Braun T, Schmitz ML. A redox-regulated SUMO/acetylation switch of HIPK2 controls the survival threshold to oxidative stress. Mol Cell 2012;46: 472-83.
    • (2012) Mol Cell , vol.46 , pp. 472-483
    • De La Vega, L.1    Grishina, I.2    Moreno, R.3    Kruger, M.4    Braun, T.5    Schmitz, M.L.6
  • 35
    • 77956186783 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes
    • Hamanaka RB, Chandel NS. Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes. Trends Biochem Sci 2010;35: 505-13.
    • (2010) Trends Biochem Sci , vol.35 , pp. 505-513
    • Hamanaka, R.B.1    Chandel, N.S.2
  • 36
    • 31544432283 scopus 로고    scopus 로고
    • Regulation of SUMOylation by reversible oxidation of SUMO conjugating enzymes
    • Bossis G, Melchior F. Regulation of SUMOylation by reversible oxidation of SUMO conjugating enzymes. Mol Cell 2006;21: 349-57.
    • (2006) Mol Cell , vol.21 , pp. 349-357
    • Bossis, G.1    Melchior, F.2
  • 37
    • 77951235215 scopus 로고    scopus 로고
    • SENP3- mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress
    • Han Y, Huang C, Sun X, Xiang B, Wang M, Yeh ET, et al. SENP3- mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress. J Biol Chem 2010;285: 12906-15.
    • (2010) J Biol Chem , vol.285 , pp. 12906-12915
    • Han, Y.1    Huang, C.2    Sun, X.3    Xiang, B.4    Wang, M.5    Yeh, E.T.6
  • 38
    • 78650650374 scopus 로고    scopus 로고
    • The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-alpha-induced priming of the NADPH oxidase in human neutrophils
    • Boussetta T, Gougerot-Pocidalo MA, Hayem G, Ciappelloni S, Raad H, Arabi Derkawi R, et al. The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-alpha-induced priming of the NADPH oxidase in human neutrophils. Blood 2010;116: 5795-802.
    • (2010) Blood , vol.116 , pp. 5795-5802
    • Boussetta, T.1    Gougerot-Pocidalo, M.A.2    Hayem, G.3    Ciappelloni, S.4    Raad, H.5    Arabi Derkawi, R.6
  • 39
    • 77952674474 scopus 로고    scopus 로고
    • Role of Pin1 in neointima formation: Down-regulation of Nrf2-dependent heme oxygenase- 1 expression by Pin1
    • Kim SE, Lee MY, LimSC, Hien TT, Kim JW, Ahn SG, et al. Role of Pin1 in neointima formation: down-regulation of Nrf2-dependent heme oxygenase- 1 expression by Pin1. Free Radic Biol Med 2010;48: 1644-53.
    • (2010) Free Radic Biol Med , vol.48 , pp. 1644-1653
    • Kim, S.E.1    Lee, M.Y.2    Limsc Hien, T.T.3    Kim, J.W.4    Ahn, S.G.5
  • 40
    • 77953535030 scopus 로고    scopus 로고
    • The functional promoter polymorphism (-842G>C) in the PIN1 gene is associated with decreased risk of breast cancer in non-Hispanic white women 55 years and younger
    • Han CH, Lu J, Wei Q, Bondy ML, Brewster AM, Yu TK, et al. The functional promoter polymorphism (-842G>C) in the PIN1 gene is associated with decreased risk of breast cancer in non-Hispanic white women 55 years and younger. Breast Cancer Res Treat 2010;122: 243-9.
    • (2010) Breast Cancer Res Treat , vol.122 , pp. 243-249
    • Han, C.H.1    Lu, J.2    Wei, Q.3    Bondy, M.L.4    Brewster, A.M.5    Yu, T.K.6
  • 41
    • 70350028604 scopus 로고    scopus 로고
    • A novel functional variant (-842G>C) in the PIN1 promoter contributes to decreased risk of squamous cell carcinoma of the head and neck by diminishing the promoter activity
    • Lu J, Hu Z, Wei S, Wang LE, Liu Z, El-Naggar AK, et al. A novel functional variant (-842G>C) in the PIN1 promoter contributes to decreased risk of squamous cell carcinoma of the head and neck by diminishing the promoter activity. Carcinogenesis 2009;30: 1717-21.
    • (2009) Carcinogenesis , vol.30 , pp. 1717-1721
    • Lu, J.1    Hu, Z.2    Wei, S.3    Wang, L.E.4    Liu, Z.5    El-Naggar, A.K.6
  • 42
    • 80054699155 scopus 로고    scopus 로고
    • The polymorphism and haplotypes of PIN1 gene are associated with the risk of lung cancer in Southern and Eastern Chinese populations
    • Lu J, Yang L, Zhao H, Liu B, Li Y, Wu H, et al. The polymorphism and haplotypes of PIN1 gene are associated with the risk of lung cancer in Southern and Eastern Chinese populations. Hum Mutat 2011;32: 1299-308.
    • (2011) Hum Mutat , vol.32 , pp. 1299-1308
    • Lu, J.1    Yang, L.2    Zhao, H.3    Liu, B.4    Li, Y.5    Wu, H.6
  • 45
    • 84856069665 scopus 로고    scopus 로고
    • A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis
    • Kessler JD, Kahle KT, Sun T, Meerbrey KL, Schlabach MR, Schmitt EM, et al. A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. Science 2012;335: 348-53.
    • (2012) Science , vol.335 , pp. 348-353
    • Kessler, J.D.1    Kahle, K.T.2    Sun, T.3    Meerbrey, K.L.4    Schlabach, M.R.5    Schmitt, E.M.6
  • 46
    • 73449119972 scopus 로고    scopus 로고
    • Sumoylation of p68 and p72RNAhelicases affects protein stability and transactivation potential
    • Mooney SM, Grande JP, Salisbury JL, Janknecht R. Sumoylation of p68 and p72RNAhelicases affects protein stability and transactivation potential. Biochemistry 2010;49: 1-10.
    • (2010) Biochemistry , vol.49 , pp. 1-10
    • Mooney, S.M.1    Grande, J.P.2    Salisbury, J.L.3    Janknecht, R.4
  • 47
    • 77951010059 scopus 로고    scopus 로고
    • The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome
    • Driscoll JJ, Pelluru D, Lefkimmiatis K, Fulciniti M, Prabhala RH, Greipp PR, et al. The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome. Blood 2010; 115: 2827-34.
    • (2010) Blood , vol.115 , pp. 2827-2834
    • Driscoll, J.J.1    Pelluru, D.2    Lefkimmiatis, K.3    Fulciniti, M.4    Prabhala, R.H.5    Greipp, P.R.6
  • 48
    • 84867909849 scopus 로고    scopus 로고
    • SUMO PTEN and tumor suppression
    • Jul 31. [Epub ahead of print].
    • Matunis MJ, Guzzo CM. SUMO, PTEN and tumor suppression. Pigment Cell Melanoma Res 2012 Jul 31. [Epub ahead of print].
    • (2012) Pigment Cell Melanoma Res
    • Matunis, M.J.1    Guzzo, C.M.2
  • 49
    • 44649135155 scopus 로고    scopus 로고
    • Regulation of the sumoylation system in gene expression
    • Liu B, Shuai K. Regulation of the sumoylation system in gene expression. Curr Opin Cell Biol 2008;20: 288-93.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 288-293
    • Liu, B.1    Shuai, K.2
  • 50
    • 27144524092 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by Pin1-targeted RNA interference in prostate cancer
    • Ryo A, Uemura H, Ishiguro H, Saitoh T, Yamaguchi A, Perrem K, et al. Stable suppression of tumorigenicity by Pin1-targeted RNA interference in prostate cancer. Clin Cancer Res 2005;11: 7523-31.
    • (2005) Clin Cancer Res , vol.11 , pp. 7523-7531
    • Ryo, A.1    Uemura, H.2    Ishiguro, H.3    Saitoh, T.4    Yamaguchi, A.5    Perrem, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.