Protective effect of lycopene against ochratoxin A induced renal oxidative stress and apoptosis in rats

Experimental and Toxicologic Pathology

Volumn 65, Issue 6, 2013, Pages 853-861

  Palabiyik, S Sezin ^a,b   Erkekoglu, Pinar ^a   Zeybek, N Dilara ^a   Kizilgun, Murat ^c   Baydar, Dilek Ertoy ^a   Sahin, Gonul ^a,d   Giray, Belma Kocer ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

^b ATATÜRK UNIVERSITY   (Turkey)

^c AY Oncology Training and Research Hospital   (Turkey)

^d EASTERN MEDITERRANEAN UNIVERSITY   (Turkey)

Author keywords

Antioxidant enzymes; Apoptosis; Kidney; Lipid peroxidation; Ochratoxin A; Oxidative stress

Indexed keywords

CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE 1; LYCOPENE; MALONALDEHYDE; OCHRATOXIN; SUPEROXIDE DISMUTASE; THIOREDOXIN REDUCTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; HISTOPATHOLOGY; KIDNEY CORTEX; KIDNEY MASS; KIDNEY MEDULLA; LIPID PEROXIDATION; MALE; NEPHROTOXICITY; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; RAT; RENAL PROTECTION; TREATMENT DURATION;

(1)O(2); 5,5′-DITHIOBIS-(2-NITROBENZOIC) ACID; 5-THIO-2-NITROBENZOIC ACID; ANTIOXIDANT ENZYMES; APOPTOSIS; BALKAN ENDEMIC NEPHROPATHY; BEN; BLOOD UREA NITROGEN; BUN; CAT; CATALASE; DIETHYLENETRIAMINE PENTAACETIC ACID; DTNB; DTPA; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE REDUCTASE; GPX1; GR; GSH; GSSG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HPLC; KIDNEY; LIPID PEROXIDATION; LP; MALONDIALDEHYDE; MDA; NADP(+); NADPH; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE, REDUCED FORM; OCHRATOXIN A; OTA; OXIDATIVE STRESS; OXIDIZED GLUTATHIONE; PHENYLMETHANESULPHONYL FLUORIDE; PMSF; REACTIVE OXYGEN SPECIES; ROS; SD; SEM; SINGLET OXYGEN; SOD; SPRAGUE DAWLEY; SPSS; STANDARD ERROR OF MEAN; STATISTICAL PACKAGE FOR SOCIAL SCIENCES PROGRAM; SUPEROXIDE DISMUTASE; TDT; TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE; TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE-MEDIATED DEOXYURIDINE TRIPHOSPHATE NICK END-LABELING; THIOREDOXIN REDUCTASE; TNB; TOTAL GLUTATHIONE; TRXR; TUNEL;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BODY WEIGHT; CAROTENOIDS; IN SITU NICK-END LABELING; KIDNEY; KIDNEY DISEASES; LIPID PEROXIDATION; MALE; OCHRATOXINS; ORGAN SIZE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 84880037441     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2012.12.004     Document Type: Article

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